Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype

Journal of Immunology

Volumn 168, Issue 5, 2002, Pages 2307-2315

  Shilling, Heather G ^a   Guethlein, Lisbeth A ^a   Cheng, Nathalie W ^a   Gardiner, Clair M ^a   Rodriguez, Roberto ^a   Tyan, Dolly ^a   Parham, Peter ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN RECEPTOR; KILLER IMMUNOGLOBULIN LIKE RECEPTOR; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ALLELISM; ARTICLE; CHROMOSOME 19; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MULTIGENE FAMILY; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

EID: 0036498793     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.5.2307     Document Type: Article

References (39)

1. NK cells, MHC class I antigens and missing self
2. Gene arrangement of the killer cell inhibitory receptor family on human chromosome 19q13.4 detected by fiber-FISH
3. Organization of the leukocyte receptor cluster (LRC) on human chromosome 19q13.4
4. The genomic organization and evolution of the natural killer immunoglobulin-like receptor (KIR) gene cluster
5. Plasticity in the organization and sequences of human KIR/ILT gene families
6. NK cell receptors
7. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors
8. The repertoire of killer cell Ig-like receptor and CD94:NKG2A receptors in T cells: Clones sharing identical alpha beta TCR rearrangement express highly diverse killer cell Ig-like receptor patterns
9. Regulation of inhibitory and activating killer-cell Ig-like receptor expression occurs in T cells after termination of TCR rearrangements
10. Regulation of immune responses through inhibitory receptors
11. Human diversity in killer cell inhibitory receptor genes
12. Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans
13. Diversity of the killer cell Ig-Iike receptors of rhesus monkeys
14. Short KIR haplotypes in pygmy chimpanzee (bonobo) resemble the conserved framework of diverse human KIR haplotypes
15. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells
16. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains
17. Identification of seventeen novel KIR variants: Fourteen of them from two non-Caucasian donors
18. Evidence for recombination as a mechanism for KIR diversification
19. Alternatively spliced forms of human killer inhibitory receptors
20. Polymorphism and domain variability of human killer cell inhibitory receptors
21. Killer cell receptors: Keeping pace with MHC class I evolution
22. The natural killer cell receptor specific for HLA-A allotypes: A novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer
23. Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism
24. Molecular cloning of NKB1: A natural killer cell receptor for HLA-B allotypes
25. A human killer inhibitory receptor specific for HLA-A1,2
26. Discovery of two novel variants of KIR2DS5 reveals this gene to be a common component of human KIR 'B' haplotypes
27. Development of a PCR-SSOP approach capable of defining the natural killer cell inhibitory receptor (KIR) gene sequence repertoires
28. Population frequencies and putative haplotypes of the killer cell immunoglobulin-like receptor sequences and evidence for recombination
29. Distribution of natural killer cell immunoglobulin-like receptor sequences in three ethnic groups
30. Genomic diversity of natural killer cell receptor genes in three populations
31. Inhibitory MHC class I receptors on NK and T cells: A standard nomenclature
32. New nomenclature for MHC receptors
33. KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains
34. HLA, 1991
35. The rise and fall of great class I genes
36. Population biology of antigen presentation by MHC class I molecules
37. Immunogenetics: Defence by diversity
38. The evolutionary dynamics of complex polymorphisms