Haplotype frequency estimation in patient populations: The effect of departures from Hardy-Weinberg proportions and collapsing over a locus in the HLA region

Genetic Epidemiology

Volumn 22, Issue 2, 2002, Pages 186-195

  Single, Richard M ^a,b   Meyer, Diogo ^b   Hollenbach, Jill A ^c   Nelson, Mark P ^d   Noble, Janelle A ^b   Erlich, Henry A ^a   Thomson, Glenys ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^d ROCHE MOLECULAR SYSTEMS   (United States)

Author keywords

Estimation accuracy; Expectation maximization algorithm; Hardy Weinberg proportions; Linkage disequilibrium

Indexed keywords

ALGORITHM; ARTICLE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; INSULIN DEPENDENT DIABETES MELLITUS; STATISTICAL ANALYSIS;

ALGORITHMS; ALLELES; DIABETES MELLITUS, TYPE 1; GENE FREQUENCY; GENES, MHC CLASS I; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, STATISTICAL; POLYMORPHISM, GENETIC;

EID: 0036143316     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.0163     Document Type: Article

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