Identification of seventeen novel KIR variants: Fourteen of them from two non-Caucasian donors

Tissue Antigens

Volumn 57, Issue 1, 2001, Pages 22-31

  Rajalingam, R ^a   Gardiner, C M ^a   Canavez, F ^a   Vilches, C ^a   Parham, P ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diversity; HLA class I receptor; Killer cell Ig like receptor; NK cells; Polymorphism

Indexed keywords

IMMUNOGLOBULIN RECEPTOR; NATURAL KILLER CELL PROTEIN; PROTEIN KIR; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME 19; GENETIC ANALYSIS; HUMAN; HUMAN CELL; NATURAL KILLER CELL; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN VARIANT; RACE DIFFERENCE;

ALLELES; CELL LINE, TRANSFORMED; EUROPEAN CONTINENTAL ANCESTRY GROUP; HUMANS; IMMUNOGLOBULINS; KILLER CELLS, NATURAL; MOLECULAR SEQUENCE DATA; RECEPTORS, IMMUNOLOGIC; VARIATION (GENETICS);

EID: 0035134574     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0039.2001.057001022.x     Document Type: Article

References (40)

1. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains
2. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells
3. Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes
4. Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes
5. Cytolytic T lymphocytes displaying natural killer (NK)-like activity: Expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production
6. NK cell receptors
7. Nucleotide and amino acid sequence alignment for human killer cell inhibitory receptors (KIR), 1998
8. NK cells, MHC class I antigens and missing self
9. KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains
10. Evidence for recombination as a mechanism for KIR diversification
11. Genomic organization and allelic polymorphism of the human killer cell inhibitory receptor gene KIR103
12. Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors
13. Alternatively spliced forms of human killer inhibitory receptors
14. Polymorphism and domain variability of human killer cell inhibitory receptors
15. NK cells receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains
16. The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions
17. A novel surface molecule homologous to the p58/p50 faimly of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation
18. The natural killer cell receptor specific for HLA-A allotypes: A novel member of the P58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer
19. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer
20. Multiple transcripts of the killer cell immunoglobulin-like receptor family, KIR3DL1 (NKB1), are expressed by natural killer cells of a single individual
21. Plasticity in the organization and sequences of human KIR/ILT gene families
22. Organization of the leukocyte receptor cluster (LRC) on human chromosome 19q13.4
23. A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors
24. Gene arrangement of the killer cell inhibitory receptor family on human chromosome 19q13.4 detected by fiber-FISH
25. The genomic organization and evolution of the natural killer immunoglobulin-like receptor (KIR) gene cluster
26. Human diversity in killer cell inhibitory receptor genes
27. Population frequencies and putative haplotypes of the killer cell immunoglobulin-like receptor sequences and evidence for recombination
28. Discovery of two novel variants of KIR2DS5 reveals this gene is a common component of human KIR 'BZ' haplotypes
29. Functionally and structurally distinct NK cell receptors repertoires in the peripheral blood of two human donors
30. Crystal structure of the human p58 killer cell inhibitory receptor (KIR2DL3) specific for HLA-Cw3-related MHC class I
31. Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors
32. Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor K1R2DL2
33. Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition
34. A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes
35. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
36. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor
37. Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases
38. Isotypic variation of novel immunoglobulin-like transcript/killer cell inhibitory receptor loci in the leukocyte receptor complex
39. Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans
40. Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand