메뉴 건너뛰기




Volumn 22, Issue 9, 2008, Pages 1174-1189

The role of the chromatin remodeler Mi-2β in hematopoietic stem cell self-renewal and multilineage differentiation

Author keywords

Chromatin; HSC; Lineage priming; Mi 2 ; Multipotency; Self renewal

Indexed keywords

ADENOSINE TRIPHOSPHATASE; MI 2BETA PROTEIN; PROTEIN; PROTEIN DERIVATIVE; SNF2 PROTEIN;

EID: 43249083123     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1642808     Document Type: Article
Times cited : (161)

References (76)
  • 2
    • 20244387299 scopus 로고    scopus 로고
    • Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
    • Adolfsson, J., Mansson, R., Buza-Vidas, N., Hultquist, A., Liuba, K., Jensen, C.T., Bryder, D., Yang, L., Borge, O.J., Thoren, L.A., et al. 2005. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121: 295-306.
    • (2005) Cell , vol.121 , pp. 295-306
    • Adolfsson, J.1    Mansson, R.2    Buza-Vidas, N.3    Hultquist, A.4    Liuba, K.5    Jensen, C.T.6    Bryder, D.7    Yang, L.8    Borge, O.J.9    Thoren, L.A.10
  • 3
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi, K., Traver, D., Miyamoto, T., and Weissman, I.L. 2000. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404: 193-197.
    • (2000) Nature , vol.404 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 4
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • Arai, F., Hirao, A., Ohmura, M., Sato, H., Matsuoka, S., Takubo, K., Ito, K., Koh, G.Y., and Suda, T. 2004. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118: 149-161.
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6    Ito, K.7    Koh, G.Y.8    Suda, T.9
  • 6
    • 33749452454 scopus 로고    scopus 로고
    • Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect
    • Bowie, M.B., McKnight, K.D., Kent, D.G., McCaffrey, L., Hoodless, P.A., and Eaves, C.J. 2006. Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. J. Clin. Invest. 116: 2808-2816.
    • (2006) J. Clin. Invest , vol.116 , pp. 2808-2816
    • Bowie, M.B.1    McKnight, K.D.2    Kent, D.G.3    McCaffrey, L.4    Hoodless, P.A.5    Eaves, C.J.6
  • 7
    • 34249711353 scopus 로고    scopus 로고
    • Steel factor responsiveness regulates the high self-renewal phenotype of fetal hematopoietic stem cells
    • Bowie, M.B., Kent, D.G., Copley, M.R., and Eaves, C.J. 2007. Steel factor responsiveness regulates the high self-renewal phenotype of fetal hematopoietic stem cells. Blood 109: 5043-5048.
    • (2007) Blood , vol.109 , pp. 5043-5048
    • Bowie, M.B.1    Kent, D.G.2    Copley, M.R.3    Eaves, C.J.4
  • 11
    • 0032980506 scopus 로고    scopus 로고
    • In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
    • Cheshier, S.H., Morrison, S.J., Liao, X., and Weissman, I.L. 1999. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc. Natl. Acad. Sci. 96: 3120-3125.
    • (1999) Proc. Natl. Acad. Sci , vol.96 , pp. 3120-3125
    • Cheshier, S.H.1    Morrison, S.J.2    Liao, X.3    Weissman, I.L.4
  • 12
    • 0035807964 scopus 로고    scopus 로고
    • Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells
    • Christensen, J.L. and Weissman, I.L. 2001. Flk-2 is a marker in hematopoietic stem cell differentiation: A simple method to isolate long-term stem cells. Proc. Natl. Acad. Sci. 98: 14541-14546.
    • (2001) Proc. Natl. Acad. Sci , vol.98 , pp. 14541-14546
    • Christensen, J.L.1    Weissman, I.L.2
  • 13
    • 33747608385 scopus 로고    scopus 로고
    • All in the family: IL-27 suppression of T(H)-17 cells
    • Colgan, J. and Rothman, P. 2006. All in the family: IL-27 suppression of T(H)-17 cells. Nat. Immunol. 7: 899-901.
    • (2006) Nat. Immunol , vol.7 , pp. 899-901
    • Colgan, J.1    Rothman, P.2
  • 14
    • 0030743240 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of hemopoietic stem cell numbers: Mapping of a stem cell gene
    • de Haan, G. and Van Zant, G. 1997. Intrinsic and extrinsic control of hemopoietic stem cell numbers: Mapping of a stem cell gene. J. Exp. Med. 186: 529-536.
    • (1997) J. Exp. Med , vol.186 , pp. 529-536
    • de Haan, G.1    Van Zant, G.2
  • 15
    • 0034665777 scopus 로고    scopus 로고
    • Transforming growth factor-β: Pleiotropic role in the regulation of hematopoiesis
    • Fortunel, N.O., Hatzfeld, A., and Hatzfeld, J.A. 2000. Transforming growth factor-β: Pleiotropic role in the regulation of hematopoiesis. Blood 96: 2022-2036.
    • (2000) Blood , vol.96 , pp. 2022-2036
    • Fortunel, N.O.1    Hatzfeld, A.2    Hatzfeld, J.A.3
  • 16
    • 0036519296 scopus 로고    scopus 로고
    • Haematopoietic cell-fate decisions, chromatin regulation and ikaros
    • Georgopoulos, K. 2002. Haematopoietic cell-fate decisions, chromatin regulation and ikaros. Nat. Rev. Immunol. 2: 162-174.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 162-174
    • Georgopoulos, K.1
  • 17
    • 12144291320 scopus 로고    scopus 로고
    • Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition
    • Gomez-del Arco, P., Maki, K., and Georgopoulos, K. 2004. Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition. Mol. Cell. Biol. 24: 2797-2807.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 2797-2807
    • Gomez-del Arco, P.1    Maki, K.2    Georgopoulos, K.3
  • 18
  • 21
    • 0026439076 scopus 로고
    • Activation of the β-globin locus control region precedes commitment to the erythroid lineage
    • Jimenez, G., Griffiths, S.D., Ford, A.M., Greaves, M.F., and Enver, T. 1992. Activation of the β-globin locus control region precedes commitment to the erythroid lineage. Proc. Natl. Acad. Sci. 89: 10618-10622.
    • (1992) Proc. Natl. Acad. Sci , vol.89 , pp. 10618-10622
    • Jimenez, G.1    Griffiths, S.D.2    Ford, A.M.3    Greaves, M.F.4    Enver, T.5
  • 22
    • 34548462072 scopus 로고    scopus 로고
    • Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors
    • Jude, C.D., Climer, L., Xu, D., Artinger, E., Fisher, J.K., and Ernst, P. 2007. Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. Cell Stem Cell 1: 324-337.
    • (2007) Cell Stem Cell , vol.1 , pp. 324-337
    • Jude, C.D.1    Climer, L.2    Xu, D.3    Artinger, E.4    Fisher, J.K.5    Ernst, P.6
  • 25
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • Kirstetter, P., Anderson, K., Porse, B.T., Jacobsen, S.E., and Nerlov, C. 2006. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat. Immunol. 7: 1048-1056.
    • (2006) Nat. Immunol , vol.7 , pp. 1048-1056
    • Kirstetter, P.1    Anderson, K.2    Porse, B.T.3    Jacobsen, S.E.4    Nerlov, C.5
  • 27
    • 0034663810 scopus 로고    scopus 로고
    • Chromatin fine structure profiles for a developmentally regulated gene: Reorganization of the lysozyme locus before trans-activator binding and gene expression
    • Kontaraki, J., Chen, H.H., Riggs, A., and Bonifer, C. 2000. Chromatin fine structure profiles for a developmentally regulated gene: Reorganization of the lysozyme locus before trans-activator binding and gene expression. Genes & Dev. 14: 2106-2122.
    • (2000) Genes & Dev , vol.14 , pp. 2106-2122
    • Kontaraki, J.1    Chen, H.H.2    Riggs, A.3    Bonifer, C.4
  • 28
    • 0029155706 scopus 로고
    • Inducible gene targeting in mice
    • Kuhn, R., Schwenk, F., Aguet, M., and Rajewsky, K. 1995. Inducible gene targeting in mice. Science 269: 1427-1429.
    • (1995) Science , vol.269 , pp. 1427-1429
    • Kuhn, R.1    Schwenk, F.2    Aguet, M.3    Rajewsky, K.4
  • 29
    • 33746906644 scopus 로고    scopus 로고
    • Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors
    • Lai, A.Y. and Kondo, M. 2006. Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. J. Exp. Med. 203: 1867-1873.
    • (2006) J. Exp. Med , vol.203 , pp. 1867-1873
    • Lai, A.Y.1    Kondo, M.2
  • 30
    • 0642282522 scopus 로고    scopus 로고
    • Stem cells: Interactive niches
    • Lemischka, I.R. and Moore, K.A. 2003. Stem cells: Interactive niches. Nature 425: 778-779.
    • (2003) Nature , vol.425 , pp. 778-779
    • Lemischka, I.R.1    Moore, K.A.2
  • 31
    • 33846594324 scopus 로고    scopus 로고
    • The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice
    • Liang, Y., Jansen, M., Aronow, B., Geiger, H., and Van Zant, G. 2007. The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice. Nat. Genet. 39: 178-188.
    • (2007) Nat. Genet , vol.39 , pp. 178-188
    • Liang, Y.1    Jansen, M.2    Aronow, B.3    Geiger, H.4    Van Zant, G.5
  • 32
    • 34247200413 scopus 로고    scopus 로고
    • CHD4/Mi-2β activity is required for the positioning of the mesoderm/neuroectoderm boundary in Xenopus
    • Linder, B., Mentele, E., Mansperger, K., Straub, T., Kremmer, E., and Rupp, R.A. 2007. CHD4/Mi-2β activity is required for the positioning of the mesoderm/neuroectoderm boundary in Xenopus. Genes & Dev. 21: 973-983.
    • (2007) Genes & Dev , vol.21 , pp. 973-983
    • Linder, B.1    Mentele, E.2    Mansperger, K.3    Straub, T.4    Kremmer, E.5    Rupp, R.A.6
  • 33
    • 34247092922 scopus 로고    scopus 로고
    • Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors
    • Mansson, R., Hultquist, A., Luc, S., Yang, L., Anderson, K., Kharazi, S., Al-Hashmi, S., Liuba, K., Thoren, L., Adolfsson, J., et al. 2007. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. Immunity 26: 407-419.
    • (2007) Immunity , vol.26 , pp. 407-419
    • Mansson, R.1    Hultquist, A.2    Luc, S.3    Yang, L.4    Anderson, K.5    Kharazi, S.6    Al-Hashmi, S.7    Liuba, K.8    Thoren, L.9    Adolfsson, J.10
  • 35
    • 21444450340 scopus 로고    scopus 로고
    • Lineage promiscuous expression of transcription factors in normal hematopoiesis
    • Miyamoto, T. and Akashi, K. 2005. Lineage promiscuous expression of transcription factors in normal hematopoiesis. Int. J. Hematol. 81: 361-367.
    • (2005) Int. J. Hematol , vol.81 , pp. 361-367
    • Miyamoto, T.1    Akashi, K.2
  • 36
    • 0036070180 scopus 로고    scopus 로고
    • Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment
    • Miyamoto, T., Iwasaki, H., Reizis, B., Ye, M., Graf, T., Weissman, I.L., and Akashi, K. 2002. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev. Cell 3: 137-147.
    • (2002) Dev. Cell , vol.3 , pp. 137-147
    • Miyamoto, T.1    Iwasaki, H.2    Reizis, B.3    Ye, M.4    Graf, T.5    Weissman, I.L.6    Akashi, K.7
  • 37
    • 33645469482 scopus 로고    scopus 로고
    • Stem cells and their niches
    • Moore, K.A. and Lemischka, I.R. 2006. Stem cells and their niches. Science 311: 1880-1885.
    • (2006) Science , vol.311 , pp. 1880-1885
    • Moore, K.A.1    Lemischka, I.R.2
  • 38
    • 0028534860 scopus 로고
    • The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
    • Morrison, S.J. and Weissman, I.L. 1994. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1: 661-673.
    • (1994) Immunity , vol.1 , pp. 661-673
    • Morrison, S.J.1    Weissman, I.L.2
  • 39
    • 36049032122 scopus 로고    scopus 로고
    • Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2β determine silencer activity and Cd4 gene expression
    • Naito, T., Gomez-Del Arco, P., Williams, C.J., and Georgopoulos, K. 2007. Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2β determine silencer activity and Cd4 gene expression. Immunity 27: 723-734.
    • (2007) Immunity , vol.27 , pp. 723-734
    • Naito, T.1    Gomez-Del Arco, P.2    Williams, C.J.3    Georgopoulos, K.4
  • 40
    • 0019982596 scopus 로고
    • Clonal origin of murine hemopoietic colonies with apparent restriction to granuclocyte-macrophage-megakaryocyte (GMM) differentiation
    • Nakahata, T. and Ogawa, M. 1982. Clonal origin of murine hemopoietic colonies with apparent restriction to granuclocyte-macrophage-megakaryocyte (GMM) differentiation. J. Cell. Physiol. 111: 239-246.
    • (1982) J. Cell. Physiol , vol.111 , pp. 239-246
    • Nakahata, T.1    Ogawa, M.2
  • 42
    • 33847607846 scopus 로고    scopus 로고
    • Ikaros and chromatin regulation in early hematopoiesis
    • Ng, S.Y., Yoshida, T., and Georgopoulos, K. 2007. Ikaros and chromatin regulation in early hematopoiesis. Curr. Opin. Immunol. 19: 116-122.
    • (2007) Curr. Opin. Immunol , vol.19 , pp. 116-122
    • Ng, S.Y.1    Yoshida, T.2    Georgopoulos, K.3
  • 43
    • 33749350639 scopus 로고    scopus 로고
    • Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice
    • Oguro, H., Iwama, A., Morita, Y., Kamijo, T., van Lohuizen, M., and Nakauchi, H. 2006. Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice. J. Exp. Med. 203: 2247-2253.
    • (2006) J. Exp. Med , vol.203 , pp. 2247-2253
    • Oguro, H.1    Iwama, A.2    Morita, Y.3    Kamijo, T.4    van Lohuizen, M.5    Nakauchi, H.6
  • 45
    • 33745549658 scopus 로고    scopus 로고
    • Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations
    • O'Neill, L.P., VerMilyea, M.D., and Turner, B.M. 2006. Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations. Nat. Genet. 38: 835-841.
    • (2006) Nat. Genet , vol.38 , pp. 835-841
    • O'Neill, L.P.1    VerMilyea, M.D.2    Turner, B.M.3
  • 47
    • 0036329807 scopus 로고    scopus 로고
    • New insights into the role of extracellular matrix during tumor onset and progression
    • Pupa, S.M., Menard, S., Forti, S., and Tagliabue, E. 2002. New insights into the role of extracellular matrix during tumor onset and progression. J. Cell. Physiol. 192: 259-267.
    • (2002) J. Cell. Physiol , vol.192 , pp. 259-267
    • Pupa, S.M.1    Menard, S.2    Forti, S.3    Tagliabue, E.4
  • 49
    • 0037131389 scopus 로고    scopus 로고
    • Stemness': Transcriptional profiling of embryonic and adult stem cells
    • Ramalho-Santos, M., Yoon, S., Matsuzaki, Y., Mulligan, R.C., and Melton, D.A. 2002. 'Stemness': Transcriptional profiling of embryonic and adult stem cells. Science 298: 597-600.
    • (2002) Science , vol.298 , pp. 597-600
    • Ramalho-Santos, M.1    Yoon, S.2    Matsuzaki, Y.3    Mulligan, R.C.4    Melton, D.A.5
  • 55
    • 0346434166 scopus 로고    scopus 로고
    • Mi-2 β associates with BRG1 and RET finger protein at the distinct regions with transcriptional activating and repressing abilities
    • Shimono, Y., Murakami, H., Kawai, K., Wade, P.A., Shimokata, K., and Takahashi, M. 2003. Mi-2 β associates with BRG1 and RET finger protein at the distinct regions with transcriptional activating and repressing abilities. J. Biol. Chem. 278: 51638-51645.
    • (2003) J. Biol. Chem , vol.278 , pp. 51638-51645
    • Shimono, Y.1    Murakami, H.2    Kawai, K.3    Wade, P.A.4    Shimokata, K.5    Takahashi, M.6
  • 58
    • 35649017133 scopus 로고    scopus 로고
    • Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes
    • Sridharan, R. and Smale, S.T. 2007. Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes. J. Biol. Chem. 282: 30227-30238.
    • (2007) J. Biol. Chem , vol.282 , pp. 30227-30238
    • Sridharan, R.1    Smale, S.T.2
  • 59
    • 0242411607 scopus 로고    scopus 로고
    • Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels
    • Suzuki, N., Suwabe, N., Ohneda, O., Obara, N., Imagawa, S., Pan, X., Motohashi, H., and Yamamoto, M. 2003. Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels. Blood 102: 3575-3583.
    • (2003) Blood , vol.102 , pp. 3575-3583
    • Suzuki, N.1    Suwabe, N.2    Ohneda, O.3    Obara, N.4    Imagawa, S.5    Pan, X.6    Motohashi, H.7    Yamamoto, M.8
  • 60
    • 14944355917 scopus 로고    scopus 로고
    • Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E)
    • Terszowski, G., Waskow, C., Conradt, P., Lenze, D., Koenigsmann, J., Carstanjen, D., Horak, I., and Rodewald, H.R. 2005. Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E). Blood 105: 1937-1945.
    • (2005) Blood , vol.105 , pp. 1937-1945
    • Terszowski, G.1    Waskow, C.2    Conradt, P.3    Lenze, D.4    Koenigsmann, J.5    Carstanjen, D.6    Horak, I.7    Rodewald, H.R.8
  • 61
    • 0032578762 scopus 로고    scopus 로고
    • Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex
    • Tong, J.K., Hassig, C.A., Schnitzler, G.R., Kingston, R.E., and Schreiber, S.L. 1998. Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. Nature 395: 917-921.
    • (1998) Nature , vol.395 , pp. 917-921
    • Tong, J.K.1    Hassig, C.A.2    Schnitzler, G.R.3    Kingston, R.E.4    Schreiber, S.L.5
  • 62
    • 33749000855 scopus 로고    scopus 로고
    • Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration
    • Trowbridge, J.J., Scott, M.P., and Bhatia, M. 2006. Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration. Proc. Natl. Acad. Sci. 103: 14134-14139.
    • (2006) Proc. Natl. Acad. Sci , vol.103 , pp. 14134-14139
    • Trowbridge, J.J.1    Scott, M.P.2    Bhatia, M.3
  • 63
    • 0032845039 scopus 로고    scopus 로고
    • Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
    • Wade, P.A., Gegonne, A., Jones, P.L., Ballestar, E., Aubry, F., and Wolffe, A.P. 1999. Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation. Nat. Genet. 23: 62-66.
    • (1999) Nat. Genet , vol.23 , pp. 62-66
    • Wade, P.A.1    Gegonne, A.2    Jones, P.L.3    Ballestar, E.4    Aubry, F.5    Wolffe, A.P.6
  • 64
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells: Units of development, units of regeneration, and units in evolution
    • Weissman, I.L. 2000. Stem cells: Units of development, units of regeneration, and units in evolution. Cell 100: 157-168.
    • (2000) Cell , vol.100 , pp. 157-168
    • Weissman, I.L.1
  • 66
    • 0032252209 scopus 로고    scopus 로고
    • NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities
    • Xue, Y., Wong, J., Moreno, G.T., Young, M.K., Cote, J., and Wang, W. 1998. NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol. Cell 2: 851-861.
    • (1998) Mol. Cell , vol.2 , pp. 851-861
    • Xue, Y.1    Wong, J.2    Moreno, G.T.3    Young, M.K.4    Cote, J.5    Wang, W.6
  • 67
    • 33747613351 scopus 로고    scopus 로고
    • Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
    • Yamazaki, S., Iwama, A., Takayanagi, S., Morita, Y., Eto, K., Ema, H., and Nakauchi, H. 2006. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells. EMBO J. 25: 3515-3523.
    • (2006) EMBO J , vol.25 , pp. 3515-3523
    • Yamazaki, S.1    Iwama, A.2    Takayanagi, S.3    Morita, Y.4    Eto, K.5    Ema, H.6    Nakauchi, H.7
  • 69
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • Yilmaz, O.H., Valdez, R., Theisen, B.K., Guo, W., Ferguson, D.O., Wu, H., and Morrison, S.J. 2006. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441: 475-482.
    • (2006) Nature , vol.441 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3    Guo, W.4    Ferguson, D.O.5    Wu, H.6    Morrison, S.J.7
  • 72
    • 31544463261 scopus 로고    scopus 로고
    • Hematopoietic stem cell exhaustion impacted by p18 INK4C and p21 Cip1/ Waf1 in opposite manners
    • Yu, H., Yuan, Y., Shen, H., and Cheng, T. 2006. Hematopoietic stem cell exhaustion impacted by p18 INK4C and p21 Cip1/ Waf1 in opposite manners. Blood 107: 1200-1206.
    • (2006) Blood , vol.107 , pp. 1200-1206
    • Yu, H.1    Yuan, Y.2    Shen, H.3    Cheng, T.4
  • 73
    • 2342601849 scopus 로고    scopus 로고
    • In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
    • Yuan, Y., Shen, H., Franklin, D.S., Scadden, D.T., and Cheng, T. 2004. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat. Cell Biol. 6: 436-442.
    • (2004) Nat. Cell Biol , vol.6 , pp. 436-442
    • Yuan, Y.1    Shen, H.2    Franklin, D.S.3    Scadden, D.T.4    Cheng, T.5
  • 74
    • 0032538293 scopus 로고    scopus 로고
    • The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities
    • Zhang, Y., LeRoy, G., Seelig, H.P., Lane, W.S., and Reinberg, D. 1998. The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities. Cell 95: 279-289.
    • (1998) Cell , vol.95 , pp. 279-289
    • Zhang, Y.1    LeRoy, G.2    Seelig, H.P.3    Lane, W.S.4    Reinberg, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.