메뉴 건너뛰기




Volumn 86, Issue 7, 2008, Pages 1538-1547

Ciliary neurotrophic factor and interleukin-6 differentially activate microglia

Author keywords

COX 2; GDNF; IL 6; Inflammation; Neurodegeneration; TNF

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CYCLOOXYGENASE 2; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 43149120225     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21620     Document Type: Article
Times cited : (58)

References (62)
  • 1
    • 0036144963 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor activates spinal cord astrocytes, stimulating their production and release of fibroblast growth factor-2, to increase motor neuron survival
    • Albrecht PJ, Dahl JP, Stoltzfus OK, Levenson R, Levison SW. 2002. Ciliary neurotrophic factor activates spinal cord astrocytes, stimulating their production and release of fibroblast growth factor-2, to increase motor neuron survival. Exp Neurol 173:46-62.
    • (2002) Exp Neurol , vol.173 , pp. 46-62
    • Albrecht, P.J.1    Dahl, J.P.2    Stoltzfus, O.K.3    Levenson, R.4    Levison, S.W.5
  • 2
    • 0038725881 scopus 로고    scopus 로고
    • Astrocytes produce CNTF during the remyelination phase of viral-induced spinal cord demyelination to stimulate FGF-2 production
    • Albrecht PJ, Murtie JC, Ness JK, Redwine JM, Enterline JR, Armstrong RC, Levison SW. 2003. Astrocytes produce CNTF during the remyelination phase of viral-induced spinal cord demyelination to stimulate FGF-2 production. Neurobiol Dis 13:89-101.
    • (2003) Neurobiol Dis , vol.13 , pp. 89-101
    • Albrecht, P.J.1    Murtie, J.C.2    Ness, J.K.3    Redwine, J.M.4    Enterline, J.R.5    Armstrong, R.C.6    Levison, S.W.7
  • 3
    • 33846911099 scopus 로고    scopus 로고
    • CNTF-activated astrocytes release a soluble trophic activity for oligodendrocyte progenitors
    • Albrecht PJ, Enterline JC, Cromer J, Levison SW. 2007. CNTF-activated astrocytes release a soluble trophic activity for oligodendrocyte progenitors. Neurochem Res 32:263-271.
    • (2007) Neurochem Res , vol.32 , pp. 263-271
    • Albrecht, P.J.1    Enterline, J.C.2    Cromer, J.3    Levison, S.W.4
  • 5
    • 0033999887 scopus 로고    scopus 로고
    • Regulation of T-cell responses by CNS antigen-presenting cells: Different roles for microglia and astrocytes
    • Aloisi F, Ria F, Adorini L. 2000. Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes. Immunol Today 21:141-147.
    • (2000) Immunol Today , vol.21 , pp. 141-147
    • Aloisi, F.1    Ria, F.2    Adorini, L.3
  • 6
    • 0025514410 scopus 로고
    • Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines
    • Arakawa Y, Sendtner M, Thoenen H. 1990. Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci 10:3507-3515.
    • (1990) J Neurosci , vol.10 , pp. 3507-3515
    • Arakawa, Y.1    Sendtner, M.2    Thoenen, H.3
  • 7
    • 0026602079 scopus 로고
    • Beta-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in semle plaques in Alzheimer's disease
    • Araujo DM, Cotman CW. 1992. Beta-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in semle plaques in Alzheimer's disease. Brain Res 569:141-145.
    • (1992) Brain Res , vol.569 , pp. 141-145
    • Araujo, D.M.1    Cotman, C.W.2
  • 8
    • 0025173499 scopus 로고
    • Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: Possible relationship to the regulation of nerve growth factor synthesis
    • Bandtlow CE, Meyer M, Lindholm D, Spranger M, Heumann R, Thoenen H. 1990. Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: possible relationship to the regulation of nerve growth factor synthesis. J Cell Biol 111:1701-1711.
    • (1990) J Cell Biol , vol.111 , pp. 1701-1711
    • Bandtlow, C.E.1    Meyer, M.2    Lindholm, D.3    Spranger, M.4    Heumann, R.5    Thoenen, H.6
  • 9
    • 0036794963 scopus 로고    scopus 로고
    • Transforming growth factor beta1 prevents IL-1beta-induced microglial activation, whereas TNFalpha- and IL-6-stimulated activation are not antagonized
    • Basu A, Krady JK, Enterline JR, Levison SW. 2002a. Transforming growth factor beta1 prevents IL-1beta-induced microglial activation, whereas TNFalpha- and IL-6-stimulated activation are not antagonized. Glia 40:109-120.
    • (2002) Glia , vol.40 , pp. 109-120
    • Basu, A.1    Krady, J.K.2    Enterline, J.R.3    Levison, S.W.4
  • 10
    • 0037101634 scopus 로고    scopus 로고
    • The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury
    • Basu A, Krady JK, O'Malley M, Styren SD, DeKosky ST, Levison SW. 2002b. The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury. J Neurosci 22:6071-6082.
    • (2002) J Neurosci , vol.22 , pp. 6071-6082
    • Basu, A.1    Krady, J.K.2    O'Malley, M.3    Styren, S.D.4    DeKosky, S.T.5    Levison, S.W.6
  • 11
    • 11844254511 scopus 로고    scopus 로고
    • Interleukin-1 and the interleukin-1 type 1 receptor are essential for the progressive neurodegeneration that ensues subsequent to a mild hypoxic/ischemic injury
    • Basu A, Lazovic J, Krady JK, Mauger DT, Rothstein RP, Smith MB, Levison SW. 2005. Interleukin-1 and the interleukin-1 type 1 receptor are essential for the progressive neurodegeneration that ensues subsequent to a mild hypoxic/ischemic injury. J Cereb Blood Flow Metab 25:17-29.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 17-29
    • Basu, A.1    Lazovic, J.2    Krady, J.K.3    Mauger, D.T.4    Rothstein, R.P.5    Smith, M.B.6    Levison, S.W.7
  • 12
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophages/microgha in multiple sclerosis and experimental allergic encephalomyelitis [see comments]
    • Benveniste EN. 1997. Role of macrophages/microgha in multiple sclerosis and experimental allergic encephalomyelitis [see comments]. J Mol Med 75:165-173.
    • (1997) J Mol Med , vol.75 , pp. 165-173
    • Benveniste, E.N.1
  • 13
    • 8644219904 scopus 로고    scopus 로고
    • Motoneurons crave glial cell line-derived neurotrophic factor
    • Bohn MC. 2004. Motoneurons crave glial cell line-derived neurotrophic factor. Exp Neurol 190:263-275.
    • (2004) Exp Neurol , vol.190 , pp. 263-275
    • Bohn, M.C.1
  • 15
    • 0346993600 scopus 로고    scopus 로고
    • Mediators of ischemic preconditioning identified by microarray analysis of rat spinal cord
    • Carmel JB, Kakinohana O, Mestril R, Young W, Marsala M, Hart RP. 2004. Mediators of ischemic preconditioning identified by microarray analysis of rat spinal cord. Exp Neurol 185:81-96.
    • (2004) Exp Neurol , vol.185 , pp. 81-96
    • Carmel, J.B.1    Kakinohana, O.2    Mestril, R.3    Young, W.4    Marsala, M.5    Hart, R.P.6
  • 16
    • 0028806045 scopus 로고
    • Corticospinal motor neurons in the adult rat: Degeneration after intracortical axotomy and protection by ciliary neurotrophic factor (CNTF)
    • Dale SM, Kuang RZ, Wei X, Varon S. 1995. Corticospinal motor neurons in the adult rat: degeneration after intracortical axotomy and protection by ciliary neurotrophic factor (CNTF). Exp Neurol 135:67-73.
    • (1995) Exp Neurol , vol.135 , pp. 67-73
    • Dale, S.M.1    Kuang, R.Z.2    Wei, X.3    Varon, S.4
  • 18
    • 0035983277 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia
    • Delgado M, Jonakait GM, Ganea D. 2002. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia. Glia 39:148-161.
    • (2002) Glia , vol.39 , pp. 148-161
    • Delgado, M.1    Jonakait, G.M.2    Ganea, D.3
  • 19
    • 0023618311 scopus 로고
    • Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells
    • Frei K, Siepl C, Groscurth P, Bodmer S, Schwerdel C, Fontana A. 1987. Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells. Eur J Immunol 17:1271-1278.
    • (1987) Eur J Immunol , vol.17 , pp. 1271-1278
    • Frei, K.1    Siepl, C.2    Groscurth, P.3    Bodmer, S.4    Schwerdel, C.5    Fontana, A.6
  • 20
    • 0035719745 scopus 로고    scopus 로고
    • Tumor necrosis factor and motoneuronal degeneration: An open problem
    • Ghezzi P, Mennini T. 2001. Tumor necrosis factor and motoneuronal degeneration: an open problem. Neuroimmunomodulation 9:178-182.
    • (2001) Neuroimmunomodulation , vol.9 , pp. 178-182
    • Ghezzi, P.1    Mennini, T.2
  • 22
    • 0032942060 scopus 로고    scopus 로고
    • Microglia as mediators of inflammatory and degenerative diseases
    • Gonzalez-Scarano F, Baltuch G. 1999. Microglia as mediators of inflammatory and degenerative diseases. Annu Rev Neurosci 22:219-240.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 219-240
    • Gonzalez-Scarano, F.1    Baltuch, G.2
  • 23
    • 0027276870 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo
    • Hagg T, Varon S. 1993. Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo. Proc Natl Acad Sci U S A 90:6315-6319.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 6315-6319
    • Hagg, T.1    Varon, S.2
  • 24
    • 0027134486 scopus 로고
    • Ciliary neurotrophic factor (CNTF) promotes low-affinity nerve growth factor receptor and CD4 expression by rat CNS microglia
    • Hagg T, Varon S, Louis JC. 1993. Ciliary neurotrophic factor (CNTF) promotes low-affinity nerve growth factor receptor and CD4 expression by rat CNS microglia. J Neuroimmunol 48:177-187.
    • (1993) J Neuroimmunol , vol.48 , pp. 177-187
    • Hagg, T.1    Varon, S.2    Louis, J.C.3
  • 26
    • 0031028141 scopus 로고    scopus 로고
    • Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain
    • Heyser CJ, Masliah E, Samimi A, Campbell IL, Gold LH. 1997. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc Natl Acad Sci U S A 94:1500-1505.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1500-1505
    • Heyser, C.J.1    Masliah, E.2    Samimi, A.3    Campbell, I.L.4    Gold, L.H.5
  • 27
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman FM, Hinton DR, Johnson K, Merrill JE. 1989. Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 170:607-612.
    • (1989) J Exp Med , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 28
    • 0029038493 scopus 로고
    • CNTF regulation of astrogliosis and the activation of microglia in the developing rat central nervous system
    • Kahn MA, Ellison JA, Speight GJ, de Vellis J. 1995. CNTF regulation of astrogliosis and the activation of microglia in the developing rat central nervous system. Brain Res 685:55-67.
    • (1995) Brain Res , vol.685 , pp. 55-67
    • Kahn, M.A.1    Ellison, J.A.2    Speight, G.J.3    de Vellis, J.4
  • 30
    • 0942287666 scopus 로고    scopus 로고
    • Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis
    • Klivenyi P, Kiaei M, Gardian G, Calingasan NY, Beal MF. 2004. Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurochem 88:576-582.
    • (2004) J Neurochem , vol.88 , pp. 576-582
    • Klivenyi, P.1    Kiaei, M.2    Gardian, G.3    Calingasan, N.Y.4    Beal, M.F.5
  • 31
    • 0033935847 scopus 로고    scopus 로고
    • Spreading depression-induced cyclooxygenase-2 expression in the cortex
    • Koistinaho J, Chan PH. 2000. Spreading depression-induced cyclooxygenase-2 expression in the cortex. Neurochem Res 25:645-651.
    • (2000) Neurochem Res , vol.25 , pp. 645-651
    • Koistinaho, J.1    Chan, P.H.2
  • 32
    • 0036795867 scopus 로고    scopus 로고
    • Differential expression of protein tyrosine kinase genes during microglial activation
    • Krady JK, Basu A, Levison SW, Milner RJ. 2002. Differential expression of protein tyrosine kinase genes during microglial activation. Glia 40:11-24.
    • (2002) Glia , vol.40 , pp. 11-24
    • Krady, J.K.1    Basu, A.2    Levison, S.W.3    Milner, R.J.4
  • 33
    • 1642554430 scopus 로고    scopus 로고
    • Microglia-derived glial cell line-derived neurotrophic factor could protect Sprague-Dawley rat astrocyte from in vitro ischemia-induced damage
    • Lee GA, Lin CH, Jiang HH, Chao HJ, Wu CL, Hsueh CM. 2004. Microglia-derived glial cell line-derived neurotrophic factor could protect Sprague-Dawley rat astrocyte from in vitro ischemia-induced damage. Neurosci Lett 356:111-114.
    • (2004) Neurosci Lett , vol.356 , pp. 111-114
    • Lee, G.A.1    Lin, C.H.2    Jiang, H.H.3    Chao, H.J.4    Wu, C.L.5    Hsueh, C.M.6
  • 35
    • 0000454477 scopus 로고
    • Astroglia in culture
    • Banker GA, Goslin K, editors, 1st ed. Cambridge, MA: MIT Press. p
    • Levison SW, McCarthy KD. 1991. Astroglia in culture. In: Banker GA, Goslin K, editors. Culturing nerve cells,1st ed. Cambridge, MA: MIT Press. p 309-336.
    • (1991) Culturing nerve cells , pp. 309-336
    • Levison, S.W.1    McCarthy, K.D.2
  • 37
    • 0033620679 scopus 로고    scopus 로고
    • The clinical potential of cyclooxygenase-2-specific inhibitors
    • Lipsky PE. 1999. The clinical potential of cyclooxygenase-2-specific inhibitors. Am J Med 106:51S-57S.
    • (1999) Am J Med , vol.106
    • Lipsky, P.E.1
  • 38
    • 0029117805 scopus 로고
    • Ciliary neurotrophic factor promotes the survival of spinal sensory neurons following axotomy but not during the period of programmed cell death
    • Lo AC, Li L, Oppenheim RW, Prevette D, Houenou LJ. 1995. Ciliary neurotrophic factor promotes the survival of spinal sensory neurons following axotomy but not during the period of programmed cell death. Exp Neurol 134:49-55.
    • (1995) Exp Neurol , vol.134 , pp. 49-55
    • Lo, A.C.1    Li, L.2    Oppenheim, R.W.3    Prevette, D.4    Houenou, L.J.5
  • 39
    • 0024467217 scopus 로고
    • Microglial cells in human brain have phenotypic characteristics related to possible function as dendritic antigen presenting cells
    • Lowe J, MacLennan KA, Powe DG, Pound JD, Palmer JB. 1989. Microglial cells in human brain have phenotypic characteristics related to possible function as dendritic antigen presenting cells. J Pathol 159:143-149.
    • (1989) J Pathol , vol.159 , pp. 143-149
    • Lowe, J.1    MacLennan, K.A.2    Powe, D.G.3    Pound, J.D.4    Palmer, J.B.5
  • 40
    • 9644272471 scopus 로고    scopus 로고
    • Molecular mechanisms responsible for microglia-derived protection of Sprague-Dawley rat brain cells during in vitro ischemia
    • Lu YZ, Lin CH, Cheng FC, Hsueh CM. 2005. Molecular mechanisms responsible for microglia-derived protection of Sprague-Dawley rat brain cells during in vitro ischemia. Neurosci Lett 373:159-164.
    • (2005) Neurosci Lett , vol.373 , pp. 159-164
    • Lu, Y.Z.1    Lin, C.H.2    Cheng, F.C.3    Hsueh, C.M.4
  • 41
    • 0030045757 scopus 로고    scopus 로고
    • Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system
    • MacLennan AJ, Vinson EN, Marks L, McLaurin DL, Pfeifer M, Lee N. 1996. Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system. J Neurosci 16:621-630.
    • (1996) J Neurosci , vol.16 , pp. 621-630
    • MacLennan, A.J.1    Vinson, E.N.2    Marks, L.3    McLaurin, D.L.4    Pfeifer, M.5    Lee, N.6
  • 42
    • 0038384081 scopus 로고    scopus 로고
    • Glial reactivity in ciliary neurotrophic factor-deficient mice after optic nerve lesion
    • Martin A, Hofmann HD, Kirsch M. 2003. Glial reactivity in ciliary neurotrophic factor-deficient mice after optic nerve lesion. J Neurosci 23:5416-5424.
    • (2003) J Neurosci , vol.23 , pp. 5416-5424
    • Martin, A.1    Hofmann, H.D.2    Kirsch, M.3
  • 43
    • 0032728897 scopus 로고    scopus 로고
    • In vivo expression of cyclooxygenase-2 in rat brain following intraparenchymal injection of bacterial endotoxin and inflammatory cytokines
    • Minghetti L, Walsh DT, Levi G, Perry VH. 1999. In vivo expression of cyclooxygenase-2 in rat brain following intraparenchymal injection of bacterial endotoxin and inflammatory cytokines. J Neuropathol Exp Neurol 58:1184-1191.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 1184-1191
    • Minghetti, L.1    Walsh, D.T.2    Levi, G.3    Perry, V.H.4
  • 45
    • 0033557201 scopus 로고    scopus 로고
    • Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice
    • Penkowa M, Moos T, Carrasco J, Hadberg H, Molinero A, Bluethmann H, Hidalgo J. 1999. Strongly compromised inflammatory response to brain injury in interleukin-6-deficient mice. Glia 25:343-357.
    • (1999) Glia , vol.25 , pp. 343-357
    • Penkowa, M.1    Moos, T.2    Carrasco, J.3    Hadberg, H.4    Molinero, A.5    Bluethmann, H.6    Hidalgo, J.7
  • 46
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. 2001. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 47
    • 0025313253 scopus 로고
    • Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity
    • Powell MB, Mitchell D, Lederman J, Buckmeier J, Zamvil SS, Graham M, Ruddle NH, Steinman L. 1990. Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity. Int Immunol 2:539-544.
    • (1990) Int Immunol , vol.2 , pp. 539-544
    • Powell, M.B.1    Mitchell, D.2    Lederman, J.3    Buckmeier, J.4    Zamvil, S.S.5    Graham, M.6    Ruddle, N.H.7    Steinman, L.8
  • 48
    • 1542396160 scopus 로고    scopus 로고
    • Inflammatory cell expression of cyclooxygenase-2 in the multiple sclerosis lesion
    • Rose JW, Hill KE, Watt HE, Carlson NG. 2004. Inflammatory cell expression of cyclooxygenase-2 in the multiple sclerosis lesion. J Neuroimmunol 149:40-49.
    • (2004) J Neuroimmunol , vol.149 , pp. 40-49
    • Rose, J.W.1    Hill, K.E.2    Watt, H.E.3    Carlson, N.G.4
  • 49
    • 0242403209 scopus 로고    scopus 로고
    • Spatiotemporal distribution of gp130 cytokines and their receptors after status epilepticus: Comparison with neuronal degeneration and microglial activation
    • Rosell DR, Nacher J, Akama KT, McEwen BS. 2003. Spatiotemporal distribution of gp130 cytokines and their receptors after status epilepticus: comparison with neuronal degeneration and microglial activation. Neuroscience 122:329-348.
    • (2003) Neuroscience , vol.122 , pp. 329-348
    • Rosell, D.R.1    Nacher, J.2    Akama, K.T.3    McEwen, B.S.4
  • 52
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj KW, Raine CS. 1988. Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23:339-346.
    • (1988) Ann Neurol , vol.23 , pp. 339-346
    • Selmaj, K.W.1    Raine, C.S.2
  • 53
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj K, Raine CS, Cannella B, Brosnan CF. 1991. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 87:949-954.
    • (1991) J Clin Invest , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 54
    • 0025325548 scopus 로고
    • Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
    • Sendtner M, Kreutzberg GW, Thoenen H. 1990. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345:440-441.
    • (1990) Nature , vol.345 , pp. 440-441
    • Sendtner, M.1    Kreutzberg, G.W.2    Thoenen, H.3
  • 55
    • 0026749255 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy [see comments]
    • Sendtner M, Schmalbruch H, Stockli KA, Carroll P, Kreutzberg GW, Thoenen H. 1992. Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy [see comments]. Nature 358:502-504.
    • (1992) Nature , vol.358 , pp. 502-504
    • Sendtner, M.1    Schmalbruch, H.2    Stockli, K.A.3    Carroll, P.4    Kreutzberg, G.W.5    Thoenen, H.6
  • 56
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM. 2000. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 69:145-182.
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 57
    • 0024281211 scopus 로고
    • Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin
    • Streit WJ, Kreutzberg GW. 1988. Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin. J Comp Neurol 268:248-263.
    • (1988) J Comp Neurol , vol.268 , pp. 248-263
    • Streit, W.J.1    Kreutzberg, G.W.2
  • 58
    • 0024340657 scopus 로고
    • Expression of Ia antigen on perivascular and microglial cells after sublethal and lethal motor neuron injury
    • Streit WJ, Graeber MB, Kreutzberg GW. 1989. Expression of Ia antigen on perivascular and microglial cells after sublethal and lethal motor neuron injury. Exp Neurol 105:115-126.
    • (1989) Exp Neurol , vol.105 , pp. 115-126
    • Streit, W.J.1    Graeber, M.B.2    Kreutzberg, G.W.3
  • 59
    • 0034234414 scopus 로고    scopus 로고
    • Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration
    • Streit WJ, Hurley SD, McGraw TS, Semple-Rowland SL. 2000. Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration. J Neurosci Res 61:10-20.
    • (2000) J Neurosci Res , vol.61 , pp. 10-20
    • Streit, W.J.1    Hurley, S.D.2    McGraw, T.S.3    Semple-Rowland, S.L.4
  • 61
    • 0035949799 scopus 로고    scopus 로고
    • Marked increase in cyclooxygenase-2 in ALS spinal cord: Implications for therapy
    • Yasojima K, Tourtellotte WW, McGeer EG, McGeer PL. 2001. Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy. Neurology 57:952-956.
    • (2001) Neurology , vol.57 , pp. 952-956
    • Yasojima, K.1    Tourtellotte, W.W.2    McGeer, E.G.3    McGeer, P.L.4
  • 62
    • 0027973511 scopus 로고
    • Cell death of spinal motoneurons in the chick embryo following deafferentation: Rescue effects of tissue extracts, soluble proteins, and neurotrophic agents
    • Yin QW, Johnson J, Prevette D, Oppenheim RW. 1994. Cell death of spinal motoneurons in the chick embryo following deafferentation: rescue effects of tissue extracts, soluble proteins, and neurotrophic agents. J Neurosci 14:7629-7640.
    • (1994) J Neurosci , vol.14 , pp. 7629-7640
    • Yin, Q.W.1    Johnson, J.2    Prevette, D.3    Oppenheim, R.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.