-
1
-
-
0027373982
-
Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism
-
Allegretto, E.A., M.R. McClurg, S.B. Lazarchik, D.L. Clemm, S.A. Kerner, M.G. Elgort, M.F. Boehm, S.K. White, J.W. Pike, and R.A. Heyman. 1993. Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism. J. biol. Chem. 268: 26625-26633.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26625-26633
-
-
Allegretto, E.A.1
McClurg, M.R.2
Lazarchik, S.B.3
Clemm, D.L.4
Kerner, S.A.5
Elgort, M.G.6
Boehm, M.F.7
White, S.K.8
Pike, J.W.9
Heyman, R.A.10
-
2
-
-
0027459082
-
Retinoic acid receptors and retinoid X receptors: Interactions with endogenous retinoic acids
-
Allenby, G., M.-T. Bocquel, M. Saunders, S. Kazmer, J. Speck, M. Rosenberger, A. Lovey, P. Kastner, J.F. Grippo, P. Chambon, and A.A. Levin. 1993. Retinoic acid receptors and retinoid X receptors: Interactions with endogenous retinoic acids. Proc. Natl. Acad. Sci. 90: 30-34.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 30-34
-
-
Allenby, G.1
Bocquel, M.-T.2
Saunders, M.3
Kazmer, S.4
Speck, J.5
Rosenberger, M.6
Lovey, A.7
Kastner, P.8
Grippo, J.F.9
Chambon, P.10
Levin, A.A.11
-
3
-
-
0026557594
-
A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and the retinoic acid receptor
-
Baniahmad, A., A.C. Kohne, and R. Renkawitz. 1992. A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and the retinoic acid receptor. EMBO J. 11: 1015-1023.
-
(1992)
EMBO J.
, vol.11
, pp. 1015-1023
-
-
Baniahmad, A.1
Kohne, A.C.2
Renkawitz, R.3
-
4
-
-
0029012163
-
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha
-
Bourguet, W., M. Ruff, P. Chambon, H. Gronemeyer, and D. Moras. 1995. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature 375: 377-382
-
(1995)
Nature
, vol.375
, pp. 377-382
-
-
Bourguet, W.1
Ruff, M.2
Chambon, P.3
Gronemeyer, H.4
Moras, D.5
-
5
-
-
0029763777
-
Identification of the first retinoid X receptor homodimer antagonist
-
Canan Koch, S.S., L.J. Dardashti, J.J. Hebert, G.E. Croston, K.S. Flatten, R.A. Heyman, and A.M. Nadzan. 1996. Identification of the first retinoid X receptor homodimer antagonist. J. Med. Chem. 39: 3229-3234.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 3229-3234
-
-
Canan Koch, S.S.1
Dardashti, L.J.2
Hebert, J.J.3
Croston, G.E.4
Flatten, K.S.5
Heyman, R.A.6
Nadzan, A.M.7
-
6
-
-
0028088730
-
Interaction of proteins with transcriptionally active estrogen receptors
-
Cavailles, V., S. Dauvois, P.S. Danielum, and M.G. Parker. 1994. Interaction of proteins with transcriptionally active estrogen receptors. Proc. Natl. Acad. Sci. 91: 10009-10013.
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 10009-10013
-
-
Cavailles, V.1
Dauvois, S.2
Danielum, P.S.3
Parker, M.G.4
-
7
-
-
0029817669
-
Role of CBP/P300 in nuclear receptor signaling
-
Chakravarti, D., V.J. LaMorte, M.C. Nelson, T. Nakajima, I.G. Schulman, H. Juguilon, M. Montminy, and R.M. Evans. 1996. Role of CBP/P300 in nuclear receptor signaling. Nature 383: 99-103.
-
(1996)
Nature
, vol.383
, pp. 99-103
-
-
Chakravarti, D.1
LaMorte, V.J.2
Nelson, M.C.3
Nakajima, T.4
Schulman, I.G.5
Juguilon, H.6
Montminy, M.7
Evans, R.M.8
-
8
-
-
0029097233
-
A transcriptional co-repressor that interacts with nuclear hormone receptors
-
Chen, J.D. and R.M. Evans. 1995. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377: 454-457.
-
(1995)
Nature
, vol.377
, pp. 454-457
-
-
Chen, J.D.1
Evans, R.M.2
-
9
-
-
0029794881
-
SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers
-
Chen, J.D., K. Umesono, and R.M. Evans. 1996. SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers. Proc. Natl. Acad. Sci. 93: 7567-7571.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 7567-7571
-
-
Chen, J.D.1
Umesono, K.2
Evans, R.M.3
-
10
-
-
0029655486
-
A shift in the ligand responsiveness of thyroid hormone receptor a induced by heterodimerization with retinoid X receptor a
-
Claret, F.-X., T. Antakly, M. Karin, and F. Saatcioglu. 1996. A shift in the ligand responsiveness of thyroid hormone receptor a induced by heterodimerization with retinoid X receptor a. Mol. Cell. Biol. 16: 219-227.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 219-227
-
-
Claret, F.-X.1
Antakly, T.2
Karin, M.3
Saatcioglu, F.4
-
11
-
-
0027526297
-
Functional inhibition of retinoic acid response by dominant negative retinoic receptor mutants
-
Damm, K., R.A. Heyman, K. Umesono, and R.A. Evans. 1993. Functional inhibition of retinoic acid response by dominant negative retinoic receptor mutants. Proc. Natl. Acad. Sci. 90: 2989-2993.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 2989-2993
-
-
Damm, K.1
Heyman, R.A.2
Umesono, K.3
Evans, R.A.4
-
12
-
-
0029002298
-
Unique response pathways are established by allosteric interactions among nuclear hormone receptors
-
Forman, B.M., K. Umesono, J. Chen, and and R.M. Evans. 1995. Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell 81: 541-550.
-
(1995)
Cell
, vol.81
, pp. 541-550
-
-
Forman, B.M.1
Umesono, K.2
Chen, J.3
Evans, R.M.4
-
13
-
-
0028233383
-
Estrogen receptor-associated proteins: Possible mediators of hormone induced transcription
-
Halachmi, S., E. Marden, G. Martin, H. MacKay, C. Abbondanza, and M. Brown. 1994. Estrogen receptor-associated proteins: Possible mediators of hormone induced transcription. Science 264: 1455-1458.
-
(1994)
Science
, vol.264
, pp. 1455-1458
-
-
Halachmi, S.1
Marden, E.2
Martin, G.3
MacKay, H.4
Abbondanza, C.5
Brown, M.6
-
14
-
-
0029132202
-
Hormone-independent repression by the thyroid hormone receptor is mediated by a nuclear receptor co-repressor N-COR
-
Hörlein, A.J., A.M. Naar, T. Heinzel, J. Torchia, B. Gloss, R. Kurokawa, A. Ryan, Y. Kamai, M. Soderstrom, C.K. Glass, and M.G. Rosenfeld. 1995. Hormone-independent repression by the thyroid hormone receptor is mediated by a nuclear receptor co-repressor N-COR. Nature 377: 397-404.
-
(1995)
Nature
, vol.377
, pp. 397-404
-
-
Hörlein, A.J.1
Naar, A.M.2
Heinzel, T.3
Torchia, J.4
Gloss, B.5
Kurokawa, R.6
Ryan, A.7
Kamai, Y.8
Soderstrom, M.9
Glass, C.K.10
Rosenfeld, M.G.11
-
15
-
-
54249116230
-
Genetic regulatory mechanisms in the synthesis of proteins
-
Jacob, F. and J. Monod. 1961. Genetic regulatory mechanisms in the synthesis of proteins. J. Mol. Biol. 3: 318-356.
-
(1961)
J. Mol. Biol.
, vol.3
, pp. 318-356
-
-
Jacob, F.1
Monod, J.2
-
16
-
-
0242587820
-
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
-
Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S.-C. Lin, R.A. Heyman, D.W. Rose, C.K. Glass, and M.G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85: 403-414.
-
(1996)
Cell
, vol.85
, pp. 403-414
-
-
Kamei, Y.1
Xu, L.2
Heinzel, T.3
Torchia, J.4
Kurokawa, R.5
Gloss, B.6
Lin, S.-C.7
Heyman, R.A.8
Rose, D.W.9
Glass, C.K.10
Rosenfeld, M.G.11
-
17
-
-
0029584593
-
Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
-
Kastner, P., M. Mark, and P. Chambon. 1995. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life? Cell 83: 859-869.
-
(1995)
Cell
, vol.83
, pp. 859-869
-
-
Kastner, P.1
Mark, M.2
Chambon, P.3
-
18
-
-
0028122988
-
Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding
-
Kurokawa, R., J. DiRenzo, M. Boehm, J. Sugarman, B. Gloss, M.G. Rosenfeld, R.A. Heyman, and C.K. Glass. 1994. Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature 371: 528-531.
-
(1994)
Nature
, vol.371
, pp. 528-531
-
-
Kurokawa, R.1
DiRenzo, J.2
Boehm, M.3
Sugarman, J.4
Gloss, B.5
Rosenfeld, M.G.6
Heyman, R.A.7
Glass, C.K.8
-
19
-
-
0029154931
-
A co-repressor specifies polarity-specific activities of retinoic acid receptors
-
Kurokawa, R., M. Soderstrom, A. Horlein, S. Halachmi, M. Brown, M.G. Rosenfeld, and C.K. Glass. 1995. A co-repressor specifies polarity-specific activities of retinoic acid receptors. Nature 377: 451-457.
-
(1995)
Nature
, vol.377
, pp. 451-457
-
-
Kurokawa, R.1
Soderstrom, M.2
Horlein, A.3
Halachmi, S.4
Brown, M.5
Rosenfeld, M.G.6
Glass, C.K.7
-
20
-
-
0029740183
-
Activation of specific RXR heterodimers by an antagonist of RXR homodimers
-
Lala, D.S., R. Mukherjee, I.G. Schulman, S.S. Canan-Koch, L.J. Dardashti, A.M. Nadzan, G.E. Croston, R.M. Evans, and R.A. Heyman. 1996. Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature 383: 450-453.
-
(1996)
Nature
, vol.383
, pp. 450-453
-
-
Lala, D.S.1
Mukherjee, R.2
Schulman, I.G.3
Canan-Koch, S.S.4
Dardashti, L.J.5
Nadzan, A.M.6
Croston, G.E.7
Evans, R.M.8
Heyman, R.A.9
-
21
-
-
0029115655
-
9-cis retinoic acid signaling: Changing partners causes some excitement
-
Leblanc, B.P. and H.G. Stunnenberg. 1995. 9-cis retinoic acid signaling: Changing partners causes some excitement. Genes & Dev. 9: 1811-1816.
-
(1995)
Genes & Dev.
, vol.9
, pp. 1811-1816
-
-
Leblanc, B.P.1
Stunnenberg, H.G.2
-
22
-
-
0028890361
-
Interaction of thyroid-hormone receptor with a conserved transcriptional mediator
-
Lee, J.W., F. Ryan, J.C. Swaffield, S.A. Johnston, and D.D. Moore. 1995. Interaction of thyroid-hormone receptor with a conserved transcriptional mediator. Nature 374: 91-94.
-
(1995)
Nature
, vol.374
, pp. 91-94
-
-
Lee, J.W.1
Ryan, F.2
Swaffield, J.C.3
Johnston, S.A.4
Moore, D.D.5
-
23
-
-
0028132140
-
Influence of a steroid receptor-DNA-binding domain on transcriptional regulatory functions
-
Lefstin, J.A., J.R. Thomas, and K.R. Yamamoto. 1994. Influence of a steroid receptor-DNA-binding domain on transcriptional regulatory functions. Genes & Dev. 8: 2842-2856.
-
(1994)
Genes & Dev.
, vol.8
, pp. 2842-2856
-
-
Lefstin, J.A.1
Thomas, J.R.2
Yamamoto, K.R.3
-
24
-
-
0028961189
-
Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region
-
Leng, X., J. Blanco, S.Y. Tsai, K. Ozato, B.W. O'Malley, and M.-J. Tsai. 1995. Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region. Mol. Cell. Biol. 15: 255-263.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 255-263
-
-
Leng, X.1
Blanco, J.2
Tsai, S.Y.3
Ozato, K.4
O'Malley, B.W.5
Tsai, M.-J.6
-
25
-
-
0030938085
-
Co-expression of nuclear receptor partners increases their solubility and biological activities
-
in press
-
Li, C., J.W.R. Schwabe, and R.M. Evans. 1997. Co-expression of nuclear receptor partners increases their solubility and biological activities. Proc. Natl. Acad. Sci. (in press).
-
(1997)
Proc. Natl. Acad. Sci.
-
-
Li, C.1
Schwabe, J.W.R.2
Evans, R.M.3
-
26
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
Mangelsdorf, D.J. and R.M. Evans. 1995. The RXR heterodimers and orphan receptors. Cell 83: 841-850.
-
(1995)
Cell
, vol.83
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
27
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
Mangelsdorf, D.J., C. Thummel, M. Beato, P. Herrlich, G. Schutz, K. Umesono, P. Kastner, M. Mark, P. Chambon, and R.M. Evans. 1995. The nuclear receptor superfamily: The second decade. Cell 83: 835-839.
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
Kastner, P.7
Mark, M.8
Chambon, P.9
Evans, R.M.10
-
28
-
-
0028846193
-
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
-
Oñate, S.A., S.Y. Tsai, M.-J. Tsai, and B.W. O'Malley. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270: 1354-1347.
-
(1995)
Science
, vol.270
, pp. 1354-11347
-
-
Oñate, S.A.1
Tsai, S.Y.2
Tsai, M.-J.3
O'Malley, B.W.4
-
29
-
-
0029643780
-
Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid
-
Renaud, J.-P., N. Rochel, M. Ruff, V. Vivat, P. Chambon, H. Gronemeyer, and D. Moras. 1995. Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid. Nature 378: 681-689.
-
(1995)
Nature
, vol.378
, pp. 681-689
-
-
Renaud, J.-P.1
Rochel, N.2
Ruff, M.3
Vivat, V.4
Chambon, P.5
Gronemeyer, H.6
Moras, D.7
-
30
-
-
0003529272
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Rose, M.D., F. Winston, and P. Hieter. 1990. Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
-
(1990)
Methods in Yeast Genetics
-
-
Rose, M.D.1
Winston, F.2
Hieter, P.3
-
31
-
-
0029085038
-
Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation
-
Schulman, I.G., D. Chakravarti, H. Juguilon, A. Romo, and R.M. Evans. 1995. Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation. Proc. Natl. Acad. Sci. 92: 8288-8292.
-
(1995)
Proc. Natl. Acad. Sci.
, vol.92
, pp. 8288-8292
-
-
Schulman, I.G.1
Chakravarti, D.2
Juguilon, H.3
Romo, A.4
Evans, R.M.5
-
32
-
-
0029938795
-
Activation and repression by nuclear hormone receptors: Hormone modulates an equilibrium between active and repressive states
-
Schulman, I.G., H. Juguilon, and R.M. Evans. 1996. Activation and repression by nuclear hormone receptors: Hormone modulates an equilibrium between active and repressive states. Mol. Cell. Biol. 16: 3807-3818.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3807-3818
-
-
Schulman, I.G.1
Juguilon, H.2
Evans, R.M.3
-
33
-
-
0030113441
-
Transcriptional control: How nuclear receptors get turned on
-
Schwabe, J.W.R. 1996. Transcriptional control: How nuclear receptors get turned on. Curr. Biol. 6: 372-374.
-
(1996)
Curr. Biol.
, vol.6
, pp. 372-374
-
-
Schwabe, J.W.R.1
-
34
-
-
0029894563
-
Intracellular receptors use a common mechanism to interpret signaling information at response elements
-
Starr, D.B., W. Matsui, J.R. Thomas, and K.R. Yamamoto. 1996. Intracellular receptors use a common mechanism to interpret signaling information at response elements. Genes & Dev. 10: 1271-1283.
-
(1996)
Genes & Dev.
, vol.10
, pp. 1271-1283
-
-
Starr, D.B.1
Matsui, W.2
Thomas, J.R.3
Yamamoto, K.R.4
-
35
-
-
0029050907
-
Mutagenesis of the ligand binding domain of the human retinoic acid receptor a identifies critical residues for 9-cis-retinoic acid binding
-
Tate, B.F. and J.F. Grippo. 1995. Mutagenesis of the ligand binding domain of the human retinoic acid receptor a identifies critical residues for 9-cis-retinoic acid binding. J. Biol. Chem. 270: 20258-20263.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20258-20263
-
-
Tate, B.F.1
Grippo, J.F.2
-
36
-
-
0028348240
-
Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptorα
-
Tate, B.F., G. Allenby, R. Janocha, S. Kazmer, J. Speck, L.J. Sturzenbecker, P. Abarzua, A.A. Levin, and J.F. Grippo. 1994. Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptorα. Mol. Cell. Biol. 14: 2323-2330.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2323-2330
-
-
Tate, B.F.1
Allenby, G.2
Janocha, R.3
Kazmer, S.4
Speck, J.5
Sturzenbecker, L.J.6
Abarzua, P.7
Levin, A.A.8
Grippo, J.F.9
-
37
-
-
0025812291
-
Direct repeats as selective response elements for the thyroid hormone, retinoic acid and vitamin D, receptors
-
Umesono, K., K.K. Murakami, C.C. Thompson, and R.M. Evans. 1991. Direct repeats as selective response elements for the thyroid hormone, retinoic acid and vitamin D, receptors. Cell 65: 1255-1266.
-
(1991)
Cell
, vol.65
, pp. 1255-1266
-
-
Umesono, K.1
Murakami, K.K.2
Thompson, C.C.3
Evans, R.M.4
-
38
-
-
0012316186
-
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and putative transcriptional intermediary factors mSUG1 and TIF1
-
vom Baur, E., C. Zechel, D. Heery, M.J.S. Heine, J.M. Garnier, V. Vivat, B. Le Douarin, H. Gronemeyer, P. Chambon, and R. Losson. 1996. Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J. 15: 110-124.
-
(1996)
EMBO J.
, vol.15
, pp. 110-124
-
-
Vom Baur, E.1
Zechel, C.2
Heery, D.3
Heine, M.J.S.4
Garnier, J.M.5
Vivat, V.6
Le Douarin, B.7
Gronemeyer, H.8
Chambon, P.9
Losson, R.10
-
39
-
-
0029643769
-
A structural role for hormone in the thyroid hormone receptor
-
Wagner, R.L., J.W. Apriletti, M.E. McGrath, B.L. West, J.D. Baxter, and R.J. Fletterick. 1995. A structural role for hormone in the thyroid hormone receptor. Nature 378: 690-697.
-
(1995)
Nature
, vol.378
, pp. 690-697
-
-
Wagner, R.L.1
Apriletti, J.W.2
McGrath, M.E.3
West, B.L.4
Baxter, J.D.5
Fletterick, R.J.6
-
40
-
-
0342616837
-
A canonical structure for the ligand-binding domain of nuclear receptors
-
Wurtz, J.-M., W. Bourguet, J.-P. Renaud, V. Vivat, P. Chambon, D. Moras, and H. Gronemeyer. 1996. A canonical structure for the ligand-binding domain of nuclear receptors. Nature Struct. Biol. 3: 87-94.
-
(1996)
Nature Struct. Biol.
, vol.3
, pp. 87-94
-
-
Wurtz, J.-M.1
Bourguet, W.2
Renaud, J.-P.3
Vivat, V.4
Chambon, P.5
Moras, D.6
Gronemeyer, H.7
-
41
-
-
0027741191
-
Functional ecdysone receptor is the product of EcR and Ultraspiracle genes
-
Yao, T.P., B.M. Forman, Z. Jiang, L. Cherbas, J.D. Chen, M. McKeown, P. Cherbas, and R.M. Evans. 1993. Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature 366: 476-479.
-
(1993)
Nature
, vol.366
, pp. 476-479
-
-
Yao, T.P.1
Forman, B.M.2
Jiang, Z.3
Cherbas, L.4
Chen, J.D.5
McKeown, M.6
Cherbas, P.7
Evans, R.M.8
|