메뉴 건너뛰기




Volumn 415, Issue 6868, 2002, Pages 187-192

Co-regulator recruitment and the mechanism of retinoic acid receptor synergy

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; CRYSTAL STRUCTURE; MOLECULAR BIOLOGY; PROTEINS;

EID: 0037050017     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/415187a     Document Type: Letter
Times cited : (272)

References (30)
  • 3
    • 0033515428 scopus 로고    scopus 로고
    • Increasing the complexity ofcoactivation in nuclear receptor signaling
    • (1999) Cell , vol.97 , pp. 5-8
    • Freedman, L.P.1
  • 4
    • 0028122988 scopus 로고
    • Regulation of retincid signalling by receptor polarity and allosteric control of ligand binding
    • (1994) Nature , vol.371 , pp. 528-531
    • Kurokawa, R.1
  • 6
    • 0029781068 scopus 로고    scopus 로고
    • Two distinct actions of retinoid-receptor ligands
    • (1996) Nature , vol.382 , pp. 819-822
    • Chen, J.Y.1
  • 7
    • 0030865548 scopus 로고    scopus 로고
    • A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers
    • (1997) EMBO J , vol.16 , pp. 5697-5709
    • Vivat, V.1
  • 8
    • 0028811341 scopus 로고
    • Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RARα)-, RARβ-, or RARγ-selective ligand in combination with a retinoid X receptor-specific ligand
    • (1995) Mol. Cell Biol , vol.15 , pp. 6481-6487
    • Roy, B.1    Taneja, R.2    Chambon, P.3
  • 9
    • 0032518944 scopus 로고    scopus 로고
    • The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways
    • (1998) EMBO J , vol.17 , pp. 507-519
    • Voegel, J.J.1
  • 10
    • 0027068077 scopus 로고
    • Retinoids selective for retinoid X receptor response pathways
    • (1992) Science , vol.258 , pp. 1944-1946
    • Lehmann, J.M.1
  • 12
    • 0032505066 scopus 로고    scopus 로고
    • Interactions controlling the assembly of nuclear-receptor heterodimers and coactivators
    • (1998) Nature , vol.395 , pp. 199-202
    • Westin, S.1
  • 13
    • 0029811878 scopus 로고    scopus 로고
    • Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists
    • (1996) J. Biol. Chem , vol.271 , pp. 22692-22696
    • Klein, E.S.1
  • 14
    • 0029097233 scopus 로고
    • A transcriptional co-repressor that interacts with nuclear hormone receptors
    • (1995) Nature , vol.377 , pp. 454-457
    • Chen, J.D.1    Evans, R.M.2
  • 15
    • 0033523917 scopus 로고    scopus 로고
    • The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors
    • (1999) Nature , vol.402 , pp. 93-96
    • Hu, X.1    Lazar, M.A.2
  • 16
    • 17544398986 scopus 로고    scopus 로고
    • Mechanism of corepressor binding and release from nuclear hormone receptors
    • (1999) Genes Dev , vol.13 , pp. 3209-3216
    • Nagy, L.1
  • 17
    • 0033572656 scopus 로고    scopus 로고
    • Molecular determinants of nuclear receptor-corepressor interaction
    • (1999) Genes Dev , vol.13 , pp. 3198-3208
    • Perissi, V.1
  • 19
    • 0034975063 scopus 로고    scopus 로고
    • The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains
    • (2001) Mol. Endocrinol , vol.15 , pp. 1049-1061
    • Cohen, R.N.1
  • 20
    • 0031688518 scopus 로고    scopus 로고
    • Transcriptional silencing is defined by isoform- and heterodimer-specific interactions between nuclear hormone receptors and corepressors
    • (1998) Mol. Cell. Biol , vol.18 , pp. 5724-5733
    • Wong, C.W.1    Privalsky, M.L.2
  • 21
    • 0033868825 scopus 로고    scopus 로고
    • Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains
    • (2000) Mol. Cell , vol.5 , pp. 289-298
    • Bourguet, W.1
  • 26
    • 0033546407 scopus 로고    scopus 로고
    • 20-Epi analogues of 1, 25-dihydroxyvitamin D 3 are highly potent inducers of DRIP coactivator complex binding to the vitamin D3 receptor
    • (1999) J. Biol. Chem , vol.274 , pp. 16838-16845
    • Yang, W.1    Freedman, L.P.2
  • 28
    • 0033166916 scopus 로고    scopus 로고
    • Versatile copurification procedure for rapid isolation of homogeneous RAR-RXR heterodimers
    • (1999) Protein Expr. Purif , vol.16 , pp. 308-314
    • Iyer, J.1
  • 29
    • 0033923621 scopus 로고    scopus 로고
    • Heterodimeric complex of RAR and RXR nuclear receptor ligand-binding domains: Purification, crystallization, and preliminary X-ray diffraction analysis
    • (2000) Protein Expr. Purif , vol.19 , pp. 284-288
    • Bourguet, W.1
  • 30
    • 0028967616 scopus 로고
    • RAR-specific agonist antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation
    • (1995) EMBO J , vol.14 , pp. 1187-1197
    • Chen, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.