Catalytic asymmetric alkylations of ketoimines. Enantioselective synthesis of N-substituted quaternary carbon stereogenic centers by Zr-catalyzed additions of dialkylzinc reagents to aryl-, alkyl-, and trifluoroalkyl-substituted ketoimines

Journal of the American Chemical Society

Volumn 130, Issue 16, 2008, Pages 5530-5541

  Fu, Peng ^a   Snapper, Marc L ^a   Hoveyda, Amir H ^a  

^a BOSTON COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; CARBON; CATALYST ACTIVITY; SUBSTITUTION REACTIONS;

CATALYTIC ENANTIOSELECTIVE ALKYLATIONS; DIALKYLZINC REAGENTS;

NITROGEN COMPOUNDS;

ALKYLATING AGENT; AMINO ACID; AMINO ACID DERIVATIVE; AMINOKETONE; CARBON; ESTER; KETONE; LIGAND; PHENYLALANINE; SODIUM CHLORIDE; TRIFLUOROKETOIMINE; VALINE; ZIRCONIUM;

ALKYLATION; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; ENANTIOSELECTIVITY; PROTEIN QUATERNARY STRUCTURE; STRUCTURE ANALYSIS; SYNTHESIS;

ALKANES; ALKENES; ALKYLATION; CATALYSIS; HYDROCARBONS, FLUORINATED; IMINES; KETONES; MODELS, CHEMICAL; ORGANOMETALLIC COMPOUNDS; STEREOISOMERISM; ZINC;

EID: 42949168465     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja8001343     Document Type: Article

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