Trifolin acetate-induced cell death in human leukemia cells is dependent on caspase-6 and activates the MAPK pathway

Apoptosis

Volumn 13, Issue 5, 2008, Pages 716-728

  Torres, Fernando ^a   Quintana, José ^a   Díaz, Jesús G ^b   Carmona, Armando J ^b   Estévez, Francisco ^a  

^a UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^b UNIVERSIDAD DE LA LAGUNA   (Spain)

Author keywords

Apoptosis; Extracellular signal regulated kinases; Flavonoids; Mitogen activated protein kinase; p38MAPK

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ALLOPURINOL; ALPHA TOCOPHEROL; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIOXIDANT; ASCORBIC ACID; CASPASE 3 INHIBITOR; CASPASE 6; CASPASE 9 INHIBITOR; CASPASE INHIBITOR; CYTOCHROME C; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TRIFOLIN ACETATE; TROLOX C; UNCLASSIFIED DRUG;

ACETYLATION; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; CASPASE 6; GALACTOSIDES; HL-60 CELLS; HUMANS; KAEMPFEROLS; MAP KINASE SIGNALING SYSTEM; REACTIVE OXYGEN SPECIES; U937 CELLS;

EID: 42149184054     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0202-0     Document Type: Article

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