Tryptophan scanning mutagenesis in TM4 of the GABAA receptor α1 subunit: Implications for modulation by inhaled anesthetics and ion channel structure

Neuropharmacology

Volumn 43, Issue 4, 2002, Pages 669-678

  Jenkins, Andrew ^a   Andreasen, Alyson ^a   Trudell, James R ^b   Harrison, Neil L ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; AMINO ACID; ASPARAGINE; CHLOROFORM; HALOTHANE; INHALATION ANESTHETIC AGENT; ION CHANNEL; ISOFLURANE; ISOLEUCINE; MEMBRANE PROTEIN; MUTANT PROTEIN; TRYPTOPHAN;

ALPHA CHAIN; ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; DRUG POTENTIATION; GENE MUTATION; HUMAN; HUMAN CELL; MODULATION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; VOLTAGE CLAMP; WILD TYPE;

AMINO ACID SEQUENCE; ANESTHETICS, INHALATION; CELLS, CULTURED; DNA; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; HUMANS; ION CHANNEL GATING; ION CHANNELS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; TRANSFECTION; TRYPTOPHAN;

EID: 0036754362     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00175-2     Document Type: Article

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