Nicotinic receptor fourth transmembrane domain: Hydrogen bonding by conserved threonine contributes to channel gating kinetics

Journal of General Physiology

Volumn 115, Issue 5, 2000, Pages 663-671

  Bouzat, Cecilia ^a   Barrantes, Francisco ^a   Sine, Steven ^b  

^a UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

^b MAYO CLINIC   (United States)

Author keywords

Fourth transmembrane domain; Hydrogen bond; Kinetic analysis; Nicotinic acetylcholine receptor channel gating; Patch clamp

Indexed keywords

COMPLEMENTARY DNA; ION CHANNEL; NICOTINIC RECEPTOR;

ARTICLE; CHOLINERGIC SYSTEM; GENE MUTATION; HUMAN; HUMAN CELL; HYDROGEN BOND; KIDNEY CELL; KINETICS; LIPID BILAYER; MEMBRANE CHANNEL; PATCH CLAMP;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; ENERGY TRANSFER; HUMANS; HYDROGEN BONDING; ION CHANNEL GATING; KIDNEY; KINETICS; MICE; MOLECULAR SEQUENCE DATA; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NICOTINIC; THREONINE;

EID: 0034059664     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.115.5.663     Document Type: Article

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