-
1
-
-
0031708266
-
Electrostatics and the ion selectivity of ligand-gated channels
-
Adcock, C., G. R. Smith, and M. S. P. Sansom. 1998. Electrostatics and the ion selectivity of ligand-gated channels. Biophys. J. 75:1211-1222.
-
(1998)
Biophys. J.
, vol.75
, pp. 1211-1222
-
-
Adcock, C.1
Smith, G.R.2
Sansom, M.S.P.3
-
2
-
-
0001513363
-
Synthetic peptides as models for ion channel proteins
-
Åkerfeldt, K. S., J. D. Lear, Z. R. Wasserman, L. A. Chung, and W. F. DeGrado. 1993. Synthetic peptides as models for ion channel proteins. Acc. Chem. Res. 26:191-197.
-
(1993)
Acc. Chem. Res.
, vol.26
, pp. 191-197
-
-
Åkerfeldt, K.S.1
Lear, J.D.2
Wasserman, Z.R.3
Chung, L.A.4
DeGrado, W.F.5
-
3
-
-
0026192274
-
Orientations of amphipathic helical peptides in membrane bilayers determined by solid-state NMR spectroscopy
-
Bechinger, B., Y. Kim, L. E. Chirlian, J. Gesell, J. M. Neumann, M. Montal, J. Tomich, M. Zasloff, and S. J. Opella. 1991. Orientations of amphipathic helical peptides in membrane bilayers determined by solid-state NMR spectroscopy. J. Biomol. NMR. 1:167-173.
-
(1991)
J. Biomol. NMR
, vol.1
, pp. 167-173
-
-
Bechinger, B.1
Kim, Y.2
Chirlian, L.E.3
Gesell, J.4
Neumann, J.M.5
Montal, M.6
Tomich, J.7
Zasloff, M.8
Opella, S.J.9
-
5
-
-
33750587438
-
Molecular dynamics with coupling to an external bath
-
Berendsen, H. J. C., J. P. M. Postma, W. F. van Gunsteren, A. DiNola, and J. R. Haak. 1984. Molecular dynamics with coupling to an external bath. J. Chem. Phys. 81:3684-3690.
-
(1984)
J. Chem. Phys.
, vol.81
, pp. 3684-3690
-
-
Berendsen, H.J.C.1
Postma, J.P.M.2
Van Gunsteren, W.F.3
DiNola, A.4
Haak, J.R.5
-
6
-
-
0004067382
-
-
Reidel, Dordrecht
-
Berendsen, H. J. C., J. P. M. Postma, W. F. van Gunsteren, and J. Hermans. 1981. Intermolecular Forces. Reidel, Dordrecht.
-
(1981)
Intermolecular Forces
-
-
Berendsen, H.J.C.1
Postma, J.P.M.2
Van Gunsteren, W.F.3
Hermans, J.4
-
7
-
-
0029633168
-
GROMACS: A message-passing parallel molecular dynamics implementation
-
Berendsen, H. J. C., D. van der Spoel, and R. van Drunen. 1995. GROMACS: A message-passing parallel molecular dynamics implementation. Comp. Phys. Comm. 95:43-56.
-
(1995)
Comp. Phys. Comm.
, vol.95
, pp. 43-56
-
-
Berendsen, H.J.C.1
Van der Spoel, D.2
Van Drunen, R.3
-
8
-
-
0030999097
-
Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidycholine at full hydration, constant pressure and constant temperature
-
Berger, O., O. Edholm, and F. Jahnig. 1997. Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidycholine at full hydration, constant pressure and constant temperature. Biophys. J. 72:2002-2013.
-
(1997)
Biophys. J.
, vol.72
, pp. 2002-2013
-
-
Berger, O.1
Edholm, O.2
Jahnig, F.3
-
9
-
-
0042213113
-
+ channel in a bilayer membrane
-
+ channel in a bilayer membrane. Biophys. J. 78:2900-2917.
-
(2000)
Biophys. J.
, vol.78
, pp. 2900-2917
-
-
Bernèche, S.1
Roux, B.2
-
10
-
-
0027279872
-
Stratification of the channel domain in neurotransmitter receptors
-
Bertrand, D., J. L. Galzi, A. Devillers-Thiéry, S. Bertrand, and J. P. Changeux. 1993. Stratification of the channel domain in neurotransmitter receptors. Curr. Opin. Cell Biol. 5:688-693.
-
(1993)
Curr. Opin. Cell Biol.
, vol.5
, pp. 688-693
-
-
Bertrand, D.1
Galzi, J.L.2
Devillers-Thiéry, A.3
Bertrand, S.4
Changeux, J.P.5
-
11
-
-
0035339231
-
Channel gating: Twist to open
-
Biggin, P. C., and M. S. P. Sansom. 2001. Channel gating: Twist to open. Curr. Biol. 11:R364-R366.
-
(2001)
Curr. Biol.
, vol.11
-
-
Biggin, P.C.1
Sansom, M.S.P.2
-
12
-
-
0036787715
-
Open-state models of a potassium channel
-
Biggin, P. C., and M. S. P. Sansom. 2002. Open-state models of a potassium channel. Biophys. J. 83:1867-1876.
-
(2002)
Biophys. J.
, vol.83
, pp. 1867-1876
-
-
Biggin, P.C.1
Sansom, M.S.P.2
-
13
-
-
0032853219
-
Cellular and molecular biology of the aquaporin water channels
-
Borgnia, M., S. Nielsen, A. Engel, and P. Agre. 1999. Cellular and molecular biology of the aquaporin water channels. Annu. Rev. Biochem. 68:425-458.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 425-458
-
-
Borgnia, M.1
Nielsen, S.2
Engel, A.3
Agre, P.4
-
14
-
-
0035956936
-
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli
-
Borgnia, M. J., and P. Agre. 2001. Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli. Proc. Natl. Acad. Sci. USA. 98:2888-2893.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2888-2893
-
-
Borgnia, M.J.1
Agre, P.2
-
15
-
-
0031563818
-
Helix packing in membrane proteins
-
Bowie, J. U. 1997. Helix packing in membrane proteins. J. Mol. Biol. 272:780-789.
-
(1997)
J. Mol. Biol.
, vol.272
, pp. 780-789
-
-
Bowie, J.U.1
-
16
-
-
0029863372
-
Molecular dynamics simulations of water within models of transbilayer pores
-
Breed, J., R. Sankararamakrishnan, I. D. Kerr, and M. S. P. Sansom. 1996. Molecular dynamics simulations of water within models of transbilayer pores. Biophys. J. 70:1643-1661.
-
(1996)
Biophys. J.
, vol.70
, pp. 1643-1661
-
-
Breed, J.1
Sankararamakrishnan, R.2
Kerr, I.D.3
Sansom, M.S.P.4
-
17
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc, K., W. J. van Dijk, R. V. Klaassen, M. Schuurmans, J. van der Oost, A. B. Smit, and T. K. Sixma. 2001. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature. 411:269-276.
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
Van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
Van der Oost, J.5
Smit, A.B.6
Sixma, T.K.7
-
19
-
-
0028226051
-
Alamethicin: A peptide model for voltage gating and protein membrane interactions
-
Cafiso, D. S. 1994. Alamethicin: A peptide model for voltage gating and protein membrane interactions. Annu. Rev. Biophys. Biomol. Struct. 23:141-165.
-
(1994)
Annu. Rev. Biophys. Biomol. Struct.
, vol.23
, pp. 141-165
-
-
Cafiso, D.S.1
-
20
-
-
0032545321
-
Structure of the MscL homolog from Mycobacterium tuberculosis: A gated mechanosensitive ion channel
-
Chang, G., R. H. Spencer, A. T. Lee, M. T. Barclay, and D. C. Rees. 1998. Structure of the MscL homolog from Mycobacterium tuberculosis: A gated mechanosensitive ion channel. Science. 282:2220-2226.
-
(1998)
Science
, vol.282
, pp. 2220-2226
-
-
Chang, G.1
Spencer, R.H.2
Lee, A.T.3
Barclay, M.T.4
Rees, D.C.5
-
21
-
-
0027057058
-
The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis
-
Changeux, J. P., J. I. Galzi, A. Devillers-Thiéry, and D. Bertrand. 1992. The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis. Quart. Rev. Biophys. 25:395-432.
-
(1992)
Quart. Rev. Biophys.
, vol.25
, pp. 395-432
-
-
Changeux, J.P.1
Galzi, J.I.2
Devillers-Thiéry, A.3
Bertrand, D.4
-
22
-
-
0025895720
-
Time-correlation analysis of simulated water motion in flexible and rigid gramicidin channels
-
Chiu, S. W., E. Jakobsson, S. Subramanian, and J. A. McCammon. 1991. Time-correlation analysis of simulated water motion in flexible and rigid gramicidin channels. Biophys. J. 60:273-285.
-
(1991)
Biophys. J.
, vol.60
, pp. 273-285
-
-
Chiu, S.W.1
Jakobsson, E.2
Subramanian, S.3
McCammon, J.A.4
-
23
-
-
0033037793
-
Simulation study of a gramicidin/lipid bilayer system in excess water and lipid. II. Rates and mechanisms of water transport
-
Chiu, S. W., S. Subramaniam, and E. Jakobsson. 1999. Simulation study of a gramicidin/lipid bilayer system in excess water and lipid. II. Rates and mechanisms of water transport. Biophys. J. 76:1939-1950.
-
(1999)
Biophys. J.
, vol.76
, pp. 1939-1950
-
-
Chiu, S.W.1
Subramaniam, S.2
Jakobsson, E.3
-
24
-
-
0026522550
-
+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region
-
+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region. J. Gen. Physiol. 99:545-572.
-
(1992)
J. Gen. Physiol.
, vol.99
, pp. 545-572
-
-
Cohen, B.N.1
Labarca, C.2
Czyzk, L.3
Davidson, N.4
Lester, H.5
-
26
-
-
33846823909
-
Particle mesh Ewald: An N.log(N) method for Ewald sums in large systems
-
Darden, T., D. York, and L. Pedersen. 1993. Particle mesh Ewald: An N.log(N) method for Ewald sums in large systems. J. Chem. Phys. 98:10089-10092.
-
(1993)
J. Chem. Phys.
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
27
-
-
0026124585
-
Electrostatics and diffusion of molecules in solution: Simulations with the University of Houston Brownian dynamics program
-
Davis, M. E., J. D. Madura, B. A. Luty, and J. A. McCammon. 1991. Electrostatics and diffusion of molecules in solution: Simulations with the University of Houston Brownian dynamics program. Comput. Phys. Comm. 62:187-197.
-
(1991)
Comput. Phys. Comm.
, vol.62
, pp. 187-197
-
-
Davis, M.E.1
Madura, J.D.2
Luty, B.A.3
McCammon, J.A.4
-
28
-
-
0035861454
-
Water permeation across biological membranes: Mechanism and dynamics of aquaporin-1 and GlpF
-
De Groot, B. L., and H. Grubmuller. 2001. Water permeation across biological membranes: Mechanism and dynamics of aquaporin-1 and GlpF. Science. 294:2353-2357.
-
(2001)
Science
, vol.294
, pp. 2353-2357
-
-
De Groot, B.L.1
Grubmuller, H.2
-
29
-
-
0034859342
-
Molecular dynamics simulations of wild-type and mutant forms of the Mycobacterium tuberculosis MscL channel
-
Elmore, D. E., and D. A. Dougherty. 2001. Molecular dynamics simulations of wild-type and mutant forms of the Mycobacterium tuberculosis MscL channel. Biophys. J. 81:1345-1359.
-
(2001)
Biophys. J.
, vol.81
, pp. 1345-1359
-
-
Elmore, D.E.1
Dougherty, D.A.2
-
30
-
-
33645961739
-
A smooth particle mesh Ewald method
-
Essmann, U., L. Perera, M. L. Berkowitz, T. Darden, H. Lee, and L. G. Pedersen. 1995. A smooth particle mesh Ewald method. J. Chem. Phys. 103:8577-8593.
-
(1995)
J. Chem. Phys.
, vol.103
, pp. 8577-8593
-
-
Essmann, U.1
Perera, L.2
Berkowitz, M.L.3
Darden, T.4
Lee, H.5
Pedersen, L.G.6
-
31
-
-
0032410913
-
Two models of the influenza A M2 channel domain: Verification by comparison
-
Forrest, L. R., W. F. DeGrado, G. R. Dieckmann, and M. S. P. Sansom. 1998. Two models of the influenza A M2 channel domain: Verification by comparison. Fold. Des. 3:443-448.
-
(1998)
Fold. Des.
, vol.3
, pp. 443-448
-
-
Forrest, L.R.1
DeGrado, W.F.2
Dieckmann, G.R.3
Sansom, M.S.P.4
-
32
-
-
0034030929
-
Exploring models of the influenza A M2 channel: MD Simulations in a lipid bilayer
-
Forrest, L. R., A. Kukol, I. T. Arkin, D. P. Tieleman, and M. S. P. Sansom. 2000. Exploring models of the influenza A M2 channel: MD Simulations in a lipid bilayer. Biophys. J. 78:55-69.
-
(2000)
Biophys. J.
, vol.78
, pp. 55-69
-
-
Forrest, L.R.1
Kukol, A.2
Arkin, I.T.3
Tieleman, D.P.4
Sansom, M.S.P.5
-
33
-
-
0032992048
-
Defining the transmembrane helix of M2 protein from influenza A by molecular dynamics simulations in a lipid bilayer
-
Forrest, L. R., D. P. Tieleman, and M. S. P. Sansom. 1999. Defining the transmembrane helix of M2 protein from influenza A by molecular dynamics simulations in a lipid bilayer. Biophys. J. 76:1886-1896.
-
(1999)
Biophys. J.
, vol.76
, pp. 1886-1896
-
-
Forrest, L.R.1
Tieleman, D.P.2
Sansom, M.S.P.3
-
34
-
-
0026656037
-
Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic
-
Galzi, J. L., A. Devillers-Thiery, N. Hussy, S. Bertrand, J. P. Changeux, and D. Bertrand. 1992. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. Nature. 359:500-505.
-
(1992)
Nature
, vol.359
, pp. 500-505
-
-
Galzi, J.L.1
Devillers-Thiery, A.2
Hussy, N.3
Bertrand, S.4
Changeux, J.P.5
Bertrand, D.6
-
35
-
-
0023277159
-
Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H] chlorpromazine labels homologous residues in the beta and delta chains
-
Giraudat, J., M. Dennis, T. Heidmann, P. Y. Haumont, F. Lederer, and J. P. Changeux. 1987. Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H] chlorpromazine labels homologous residues in the beta and delta chains. Biochemistry. 26:2410-2418.
-
(1987)
Biochemistry
, vol.26
, pp. 2410-2418
-
-
Giraudat, J.1
Dennis, M.2
Heidmann, T.3
Haumont, P.Y.4
Lederer, F.5
Changeux, J.P.6
-
36
-
-
0034677524
-
Mapping the conformational wave of acetylcholine receptor channel gating
-
Grosman, C., M. Zhou, and A. Auerbach. 2000. Mapping the conformational wave of acetylcholine receptor channel gating. Nature. 403:773-776.
-
(2000)
Nature
, vol.403
, pp. 773-776
-
-
Grosman, C.1
Zhou, M.2
Auerbach, A.3
-
39
-
-
0035039272
-
Structural determinants of MscL gating studied by molecular dynamics simulations
-
Gullingsrud, J., D. Kosztin, and K. Schulten. 2001. Structural determinants of MscL gating studied by molecular dynamics simulations. Biophys. J. 80:2074-2081.
-
(2001)
Biophys. J.
, vol.80
, pp. 2074-2081
-
-
Gullingsrud, J.1
Kosztin, D.2
Schulten, K.3
-
40
-
-
84990424072
-
A consistent empirical potential for water-protein interactions
-
Hermans, J., H. J. C. Berendsen, W. F. van Gunsteren, and J. P. M. Postma. 1984. A consistent empirical potential for water-protein interactions. Biopolymers. 23:1513-1518.
-
(1984)
Biopolymers
, vol.23
, pp. 1513-1518
-
-
Hermans, J.1
Berendsen, H.J.C.2
Van Gunsteren, W.F.3
Postma, J.P.M.4
-
41
-
-
0000388705
-
LINCS: A linear constraint solver for molecular simulations
-
Hess, B., H. Bekker, H. J. C. Berendsen, and J. G. E. M. Fraaije. 1997. LINCS: A linear constraint solver for molecular simulations. J. Comp. Chem. 18:1463-1472.
-
(1997)
J. Comp. Chem.
, vol.18
, pp. 1463-1472
-
-
Hess, B.1
Bekker, H.2
Berendsen, H.J.C.3
Fraaije, J.G.E.M.4
-
42
-
-
0024419883
-
The selectivity filter of a ligand-gated ion channel
-
Hucho, F., and R. Hilgenfeld. 1989. The selectivity filter of a ligand-gated ion channel. FEBS Lett. 257:17-23.
-
(1989)
FEBS Lett.
, vol.257
, pp. 17-23
-
-
Hucho, F.1
Hilgenfeld, R.2
-
43
-
-
0030011258
-
The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor
-
Hucho, F., V. I. Tsetlin, and J. Machold. 1996. The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor. Eur. J. Biochem. 239:539-557.
-
(1996)
Eur. J. Biochem.
, vol.239
, pp. 539-557
-
-
Hucho, F.1
Tsetlin, V.I.2
Machold, J.3
-
44
-
-
0035829539
-
Water conduction through the hydrophobic channel of a carbon nanotube
-
Hummer, G., J. C. Rasaiah, and J. P. Noworyta. 2001. Water conduction through the hydrophobic channel of a carbon nanotube. Nature. 414:188-190.
-
(2001)
Nature
, vol.414
, pp. 188-190
-
-
Hummer, G.1
Rasaiah, J.C.2
Noworyta, J.P.3
-
46
-
-
0023748825
-
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance
-
Imoto, K., C. Busch, B. Sakmann, M. Mishina, T. Konno, J. Nakai, H. Buyo, Y. Mori, K. Kukuda, and S. Numa. 1988. Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance. Nature. 335:645-648.
-
(1988)
Nature
, vol.335
, pp. 645-648
-
-
Imoto, K.1
Busch, C.2
Sakmann, B.3
Mishina, M.4
Konno, T.5
Nakai, J.6
Buyo, H.7
Mori, Y.8
Kukuda, K.9
Numa, S.10
-
47
-
-
0022975736
-
Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel
-
Imoto, K., C. Methfessel, B. Sakmann, M. Mishina, Y. Mori, T. Konno, K. Fukuda, M. Kurasaki, H. Bujo, Y. Fujita, and S. Numa. 1986. Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel. Nature. 324:670-674.
-
(1986)
Nature
, vol.324
, pp. 670-674
-
-
Imoto, K.1
Methfessel, C.2
Sakmann, B.3
Mishina, M.4
Mori, Y.5
Konno, T.6
Fukuda, K.7
Kurasaki, M.8
Bujo, H.9
Fujita, Y.10
Numa, S.11
-
48
-
-
0037198626
-
Crystal structure and mechanism of a calcium-gated potassium channel
-
Jiang, Y., A. Lee, J. Chen, M. Cadene, B. T. Chait, and R. MacKinnon. 2002a. Crystal structure and mechanism of a calcium-gated potassium channel. Nature. 417:515-522.
-
(2002)
Nature
, vol.417
, pp. 515-522
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Cadene, M.4
Chait, B.T.5
MacKinnon, R.6
-
49
-
-
0037198625
-
The open pore conformation of potassium channels
-
Jiang, Y., A. Lee, J. Chen, M. Cadene, B. T. Chait, and R. MacKinnon. 2002b. The open pore conformation of potassium channels. Nature. 417:523-526.
-
(2002)
Nature
, vol.417
, pp. 523-526
-
-
Jiang, Y.1
Lee, A.2
Chen, J.3
Cadene, M.4
Chait, B.T.5
MacKinnon, R.6
-
50
-
-
0020997912
-
Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
-
Kabsch, W., and C. Sander. 1983. Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features. Biopolymers. 22:2577-2637.
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
-
51
-
-
0028070549
-
Parallel helix bundles and ion channels: Molecular modeling via simulated annealing and restrained molecular dynamics
-
Kerr, I. D., R. Sankararamakrishnan, O. S. Smart, and M. S. P. Sansom. 1994. Parallel helix bundles and ion channels: Molecular modeling via simulated annealing and restrained molecular dynamics. Biophys. J. 67:1501-1515.
-
(1994)
Biophys. J.
, vol.67
, pp. 1501-1515
-
-
Kerr, I.D.1
Sankararamakrishnan, R.2
Smart, O.S.3
Sansom, M.S.P.4
-
52
-
-
0034284386
-
How proteins adapt to a membrane-water interface
-
Killian, J. A., and G. von Heijne. 2000. How proteins adapt to a membrane-water interface. Trends Biochem. Sci. 25:429-434.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 429-434
-
-
Killian, J.A.1
Von Heijne, G.2
-
53
-
-
0025802063
-
Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel
-
Konno, T., C. Busch, E. von Kitzing, K. Imoto, F. Wang, J. Nakai, M. Mishina, S. Numa, and B. Sakmann. 1991. Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel. Proc. R. Soc. Lond. 244:69-79.
-
(1991)
Proc. R. Soc. Lond.
, vol.244
, pp. 69-79
-
-
Konno, T.1
Busch, C.2
Von Kitzing, E.3
Imoto, K.4
Wang, F.5
Nakai, J.6
Mishina, M.7
Numa, S.8
Sakmann, B.9
-
54
-
-
0030777711
-
Transmembrane four-helix bundle of influenza A M2 protein channel: Structural implications from helix tilt and orientation
-
Kovacs, F. A., and T. A. Cross. 1997. Transmembrane four-helix bundle of influenza A M2 protein channel: Structural implications from helix tilt and orientation. Biophys. J. 73:2511-2517.
-
(1997)
Biophys. J.
, vol.73
, pp. 2511-2517
-
-
Kovacs, F.A.1
Cross, T.A.2
-
55
-
-
0026244229
-
MolScript: A program to produce both detailed and schematic plots of protein structures
-
Kraulis, P. J. 1991. MolScript: A program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24:946-950.
-
(1991)
J. Appl. Crystallogr.
, vol.24
, pp. 946-950
-
-
Kraulis, P.J.1
-
56
-
-
0029163027
-
Channel guting governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors
-
Labarca, C., M. W. Nowak, H. Y. Zhang, L. X. Tang, P. Deshpande, and H. A. Lester. 1995. Channel guting governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Nature. 376:514-516.
-
(1995)
Nature
, vol.376
, pp. 514-516
-
-
Labarca, C.1
Nowak, M.W.2
Zhang, H.Y.3
Tang, L.X.4
Deshpande, P.5
Lester, H.A.6
-
57
-
-
0033996292
-
Structure and dynamics of the pore-lining helix of the nicotinic receptor: MD simulations in water, lipid bilayers and transbilayer bundles
-
Law, R. J., L. R. Forrest, K. M. Ranatunga, P. La Rocca, D. P. Tieleman, and M. S. P. Sansom. 2000. Structure and dynamics of the pore-lining helix of the nicotinic receptor: MD simulations in water, lipid bilayers and transbilayer bundles. Proteins: Struct. Func. Genet. 39:47-55.
-
(2000)
Proteins: Struct. Func. Genet.
, vol.39
, pp. 47-55
-
-
Law, R.J.1
Forrest, L.R.2
Ranatunga, K.M.3
La Rocca, P.4
Tieleman, D.P.5
Sansom, M.S.P.6
-
58
-
-
0023907575
-
Synthetic amphiphilic peptide models for protein ion channels
-
Lear, J. D., Z. R. Wasserman, and W. F. DeGrado. 1988. Synthetic amphiphilic peptide models for protein ion channels. Science. 240:1177-1181.
-
(1988)
Science
, vol.240
, pp. 1177-1181
-
-
Lear, J.D.1
Wasserman, Z.R.2
DeGrado, W.F.3
-
59
-
-
0024213680
-
Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor
-
Leonard, R. J., C. G. Labarca, P. Chamet, N. Davidson, and H. A. Lester. 1988. Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor. Science. 242:1578-1581.
-
(1988)
Science
, vol.242
, pp. 1578-1581
-
-
Leonard, R.J.1
Labarca, C.G.2
Chamet, P.3
Davidson, N.4
Lester, H.A.5
-
60
-
-
0026684455
-
The permeation pathway of neurotransmitter-gated ion channels
-
Lester, H. 1992. The permeation pathway of neurotransmitter-gated ion channels. Annu. Rev. Biophys. Biomol. Struct. 21:267-292.
-
(1992)
Annu. Rev. Biophys. Biomol. Struct.
, vol.21
, pp. 267-292
-
-
Lester, H.1
-
61
-
-
0034817286
-
Structure of the KesA channel intracellular gate in the open state
-
Liu, Y. S., P. Sompornpisut, and E. Perozo. 2001. Structure of the KesA channel intracellular gate in the open state. Nature Struct. Biol. 8:883-887.
-
(2001)
Nature Struct. Biol.
, vol.8
, pp. 883-887
-
-
Liu, Y.S.1
Sompornpisut, P.2
Perozo, E.3
-
62
-
-
0031764019
-
NMR structural studies of membrane proteins
-
Marassi, F. M., and S. J. Opella. 1998. NMR structural studies of membrane proteins. Curr. Opin. Struct. Biol. 8:640-648.
-
(1998)
Curr. Opin. Struct. Biol.
, vol.8
, pp. 640-648
-
-
Marassi, F.M.1
Opella, S.J.2
-
63
-
-
0030457853
-
Molecular dynamics simulations of ion channels formed by bundles of amphipathic α-helical peptides
-
Mitton, P., and M. S. P. Sansom. 1996. Molecular dynamics simulations of ion channels formed by bundles of amphipathic α-helical peptides. Eur. Biophys. J. 25:139-150.
-
(1996)
Eur. Biophys. J.
, vol.25
, pp. 139-150
-
-
Mitton, P.1
Sansom, M.S.P.2
-
64
-
-
0032967642
-
Nicotinic acetylcholine receptor at 4.6 angstrom resolution: Transverse tunnels in the channel wall
-
Miyazawa, A., Y. Fujiyoshi, M. Stowell, and N. Unwin. 1999. Nicotinic acetylcholine receptor at 4.6 angstrom resolution: Transverse tunnels in the channel wall. J. Mol. Biol. 288:765-786.
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 765-786
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Stowell, M.3
Unwin, N.4
-
65
-
-
0029150299
-
Design of molecular function: Channels of communication
-
Montal, M. 1995. Design of molecular function: Channels of communication. Annu. Rev. Biophys. Biomol. Struct. 24:31-57.
-
(1995)
Annu. Rev. Biophys. Biomol. Struct.
, vol.24
, pp. 31-57
-
-
Montal, M.1
-
66
-
-
0027209828
-
Synthetic peptides and four-helix bundle proteins as model systems for the pore-forming structure of channel proteins. I. Transmembrane segment M2 of nicotinic cholinergic receptor channel is a key pore-lining structure
-
Montal, M. O., L. K. Buhler, T. Iwamoto, J. M. Tomich, and M. Montal. 1993a. Synthetic peptides and four-helix bundle proteins as model systems for the pore-forming structure of channel proteins. I. Transmembrane segment M2 of nicotinic cholinergic receptor channel is a key pore-lining structure. J. Biol. Chem. 268:14601-14607.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14601-14607
-
-
Montal, M.O.1
Buhler, L.K.2
Iwamoto, T.3
Tomich, J.M.4
Montal, M.5
-
67
-
-
0027403316
-
Design, synthesis and functional characterization of a pentameric channel protein that mimics the presumed pore structure of the nicotinic cholinergic receptor
-
Montal, M. O., T. Iwamoto, J. M. Tomich, and M. Montal. 1993b. Design, synthesis and functional characterization of a pentameric channel protein that mimics the presumed pore structure of the nicotinic cholinergic receptor. FEBS Lett. 320:261-266.
-
(1993)
FEBS Lett.
, vol.320
, pp. 261-266
-
-
Montal, M.O.1
Iwamoto, T.2
Tomich, J.M.3
Montal, M.4
-
68
-
-
0010528163
-
M2δ, a candidate for the structure lining the ionic channel of the nicotinic cholinergic receptor
-
Oiki, S., W. Danho, V. Madison, and M. Montal. 1988. M2δ, a candidate for the structure lining the ionic channel of the nicotinic cholinergic receptor. Proc. Natl. Acad. Sci. USA. 85:8703-8707.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 8703-8707
-
-
Oiki, S.1
Danho, W.2
Madison, V.3
Montal, M.4
-
69
-
-
0032919444
-
Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy
-
Opella, S. J., F. M. Marassi, J. J. Gesell, A. P. Valente, Y. Kim, M. OblattMontal, and M. Montal. 1999. Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy. Nat. Struct. Biol. 6:374-379.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 374-379
-
-
Opella, S.J.1
Marassi, F.M.2
Gesell, J.J.3
Valente, A.P.4
Kim, Y.5
OblattMontal, M.6
Montal, M.7
-
70
-
-
0034926431
-
Nuclear magnetic resonance of membrane-associated peptides and proteins
-
Opella, S. J., C. Ma, and F. M. Marassi. 2001. Nuclear magnetic resonance of membrane-associated peptides and proteins. Methods Enzymol. 339:285-313.
-
(2001)
Methods Enzymol.
, vol.339
, pp. 285-313
-
-
Opella, S.J.1
Ma, C.2
Marassi, F.M.3
-
71
-
-
0036522962
-
Evidence for a centrally located gate in the pore of a serotonin-gated ion channel
-
Panicker, S., H. Cruz, C. Arrabit, and P. A. Slesinger. 2002. Evidence for a centrally located gate in the pore of a serotonin-gated ion channel. J. Neurosci. 22:1629-1639.
-
(2002)
J. Neurosci.
, vol.22
, pp. 1629-1639
-
-
Panicker, S.1
Cruz, H.2
Arrabit, C.3
Slesinger, P.A.4
-
74
-
-
0032705715
-
Molecular dynamics of synthetic leucine-serine ion channels in a phospholipid membrane
-
Randa, H. S., L. R. Forrest, G. A. Voth, and M. S. P. Sansom. 1999. Molecular dynamics of synthetic leucine-serine ion channels in a phospholipid membrane. Biophys. J. 77:2400-2410.
-
(1999)
Biophys. J.
, vol.77
, pp. 2400-2410
-
-
Randa, H.S.1
Forrest, L.R.2
Voth, G.A.3
Sansom, M.S.P.4
-
75
-
-
0036117729
-
The molecular basis of the structure and function of the 5-HT3 receptor: A model ligand-gated ion channel
-
Reeves, D. C., and S. C. R. Lummis. 2002. The molecular basis of the structure and function of the 5-HT3 receptor: A model ligand-gated ion channel. Mol. Membr. Biol. 19:11-26.
-
(2002)
Mol. Membr. Biol.
, vol.19
, pp. 11-26
-
-
Reeves, D.C.1
Lummis, S.C.R.2
-
76
-
-
0026079817
-
Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor
-
Revah, F., D. Bertrand, J. L. Galzi, A. Devillers-Thiery, C. Mulle, N. Hussy, S. Bertrand, M. Ballivet, and J. P. Changeux. 1991. Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor. Nature. 353:846-849.
-
(1991)
Nature
, vol.353
, pp. 846-849
-
-
Revah, F.1
Bertrand, D.2
Galzi, J.L.3
Devillers-Thiery, A.4
Mulle, C.5
Hussy, N.6
Bertrand, S.7
Ballivet, M.8
Changeux, J.P.9
-
77
-
-
0030735981
-
Influence of the membrane potential on the free energy of an intrinsic protein
-
Roux, B. 1997. Influence of the membrane potential on the free energy of an intrinsic protein. Biophys. J. 73:2980-2989.
-
(1997)
Biophys. J.
, vol.73
, pp. 2980-2989
-
-
Roux, B.1
-
78
-
-
0036286655
-
Computer simulation studies of model biological membranes
-
Saiz, L., and M. L. Klein. 2002a. Computer simulation studies of model biological membranes. Acc. Chem. Res. 35:482-489.
-
(2002)
Acc. Chem. Res.
, vol.35
, pp. 482-489
-
-
Saiz, L.1
Klein, M.L.2
-
79
-
-
12244294104
-
Structure of the pore region of the nicotinic acetylcholine receptor ion channel: A molecular dynamics simulation study
-
Saiz, L., and M. L. Klein. 2002b. Structure of the pore region of the nicotinic acetylcholine receptor ion channel: A molecular dynamics simulation study. Biophys. J. 82:560a.
-
(2002)
Biophys. J.
, vol.82
-
-
Saiz, L.1
Klein, M.L.2
-
80
-
-
0027817476
-
Structure and function of channel-forming peptaibols
-
Sansom, M. S. P. 1993. Structure and function of channel-forming peptaibols. Quart. Rev. Biophys. 26:365-421.
-
(1993)
Quart. Rev. Biophys.
, vol.26
, pp. 365-421
-
-
Sansom, M.S.P.1
-
81
-
-
0035829580
-
Water at the nanoscale
-
Sansom, M. S. P., and M. S. P. Biggin. 2001. Water at the nanoscale. Nature. 414:156-159.
-
(2001)
Nature
, vol.414
, pp. 156-159
-
-
Sansom, M.S.P.1
Biggin, M.S.P.2
-
82
-
-
0032442211
-
Viral ion channels: Molecular modeling and simulation
-
Sansom, M. S. P., L. R. Forrest, and R. Bull. 1998. Viral ion channels: Molecular modeling and simulation. Bioessays. 20:992-1000.
-
(1998)
Bioessays
, vol.20
, pp. 992-1000
-
-
Sansom, M.S.P.1
Forrest, L.R.2
Bull, R.3
-
83
-
-
0030777710
-
The dielectric properties of water within model transbilayer pores
-
Sansom, M. S. P., G. R. Smith, C. Adcock, and P. C. Biggin. 1997. The dielectric properties of water within model transbilayer pores. Biophys. J. 73:2404-2415.
-
(1997)
Biophys. J.
, vol.73
, pp. 2404-2415
-
-
Sansom, M.S.P.1
Smith, G.R.2
Adcock, C.3
Biggin, P.C.4
-
84
-
-
0037133320
-
Intrinsic flexibility and gating mechanism of the potassium channel KcsA
-
Shen, Y. F., Y. F. Kong, and J. P. Ma. 2002. Intrinsic flexibility and gating mechanism of the potassium channel KcsA. Proc. Nat. Acad. Sci. USA. 99:1949-1953.
-
(2002)
Proc. Nat. Acad. Sci. USA
, vol.99
, pp. 1949-1953
-
-
Shen, Y.F.1
Kong, Y.F.2
Ma, J.P.3
-
85
-
-
0034036372
-
Simulations of ion permeation through a potassium channel: Molecular dynamics of KcsA in a phospholipid bilayer
-
Shrivastava, I. H., and M. S. P. Sansom. 2000. Simulations of ion permeation through a potassium channel: Molecular dynamics of KcsA in a phospholipid bilayer. Biophys. J. 78:557-570.
-
(2000)
Biophys. J.
, vol.78
, pp. 557-570
-
-
Shrivastava, I.H.1
Sansom, M.S.P.2
-
86
-
-
0036619450
-
Molecular dynamics simulations and KcsA channel gating
-
Shrivastava, I. H., and M. S. P. Sansom. 2002. Molecular dynamics simulations and KcsA channel gating. Eur. Biophys. J. 31:207-216.
-
(2002)
Eur. Biophys. J.
, vol.31
, pp. 207-216
-
-
Shrivastava, I.H.1
Sansom, M.S.P.2
-
87
-
-
0031042584
-
A novel method for structure-based prediction of ion channel conductance properties
-
Smart, O. S., J. Breed, G. R. Smith, and M. S. P. Sansom. 1997. A novel method for structure-based prediction of ion channel conductance properties. Biophys. J. 72:1109-1126.
-
(1997)
Biophys. J.
, vol.72
, pp. 1109-1126
-
-
Smart, O.S.1
Breed, J.2
Smith, G.R.3
Sansom, M.S.P.4
-
88
-
-
0032228375
-
Structure-based prediction of the conductance properties of ion channels
-
Smart, O. S., G. M. P. Coates, M. S. P. Sansom, G. M. Alder, and C. L. Bashford. 1998. Structure-based prediction of the conductance properties of ion channels. Faraday Discuss. 111:185-199.
-
(1998)
Faraday Discuss.
, vol.111
, pp. 185-199
-
-
Smart, O.S.1
Coates, G.M.P.2
Sansom, M.S.P.3
Alder, G.M.4
Bashford, C.L.5
-
90
-
-
0030404988
-
HOLE: A program for the analysis of the pore dimensions of ion channel structural models
-
Smart, O. S., J. G. Neduvelil, X. Wang, B. A. Wallace, and M. S. P. Sansom. 1996. HOLE: A program for the analysis of the pore dimensions of ion channel structural models. J. Mol. Graph. 14:354-360.
-
(1996)
J. Mol. Graph.
, vol.14
, pp. 354-360
-
-
Smart, O.S.1
Neduvelil, J.G.2
Wang, X.3
Wallace, B.A.4
Sansom, M.S.P.5
-
92
-
-
0035825634
-
The gating mechanism of the large mechanosensitive channel MscL
-
Sukharev, S., M. Betanzos, C. S. Chiang, and H. R. Guy. 2001. The gating mechanism of the large mechanosensitive channel MscL. Nature. 409:720-724.
-
(2001)
Nature
, vol.409
, pp. 720-724
-
-
Sukharev, S.1
Betanzos, M.2
Chiang, C.S.3
Guy, H.R.4
-
93
-
-
0037134267
-
Control of the selectivity of the aquaporin water channel family by global orientational tuning
-
Tajkhorshid, E., P. Nollert, M. O. Jensen, L. J. W. Miercke, J. O'Connell, R. M. Stroud, and K. Schulten. 2002. Control of the selectivity of the aquaporin water channel family by global orientational tuning. Science. 296:525-530.
-
(2002)
Science
, vol.296
, pp. 525-530
-
-
Tajkhorshid, E.1
Nollert, P.2
Jensen, M.O.3
Miercke, L.J.W.4
O'Connell, J.5
Stroud, R.M.6
Schulten, K.7
-
94
-
-
0036286167
-
1 subunit: Model of pore architecture and channel gating
-
1 subunit: Model of pore architecture and channel gating. Biophys. J. 83:252-262.
-
(2002)
Biophys. J.
, vol.83
, pp. 252-262
-
-
Tang, P.1
Mandal, P.K.2
Xu, Y.3
-
95
-
-
0000112789
-
Molecular dynamics simulations of a fully hydrated dipalmitoylphosphatidycholine bilayer with different macroscopic boundary conditions and parameters
-
Tieleman, D. P., and H. J. C. Berendsen. 1996. Molecular dynamics simulations of a fully hydrated dipalmitoylphosphatidycholine bilayer with different macroscopic boundary conditions and parameters. J. Chem. Phys. 105:4871-4880.
-
(1996)
J. Chem. Phys.
, vol.105
, pp. 4871-4880
-
-
Tieleman, D.P.1
Berendsen, H.J.C.2
-
96
-
-
0033035249
-
An alamethicin channel in a lipid bilayer: Molecular dynamics simulations
-
Tieleman, D. P., H. J. C. Berendsen, and M. S. P. Sansom. 1999a. An alamethicin channel in a lipid bilayer: Molecular dynamics simulations. Biophys. J. 76:1757-1769.
-
(1999)
Biophys. J.
, vol.76
, pp. 1757-1769
-
-
Tieleman, D.P.1
Berendsen, H.J.C.2
Sansom, M.S.P.3
-
97
-
-
0035705881
-
Simulation approaches to ion channel structure-function relationships
-
Tieleman, D. P., P. C. Biggin, G. R. Smith, and M. S. P. Sansom. 2001. Simulation approaches to ion channel structure-function relationships. Quart. Rev. Biophys. 34:473-561.
-
(2001)
Quart. Rev. Biophys.
, vol.34
, pp. 473-561
-
-
Tieleman, D.P.1
Biggin, P.C.2
Smith, G.R.3
Sansom, M.S.P.4
-
98
-
-
0036841855
-
Analysis and evaluation of channel models: Simulations of alamethicin
-
In press
-
Tieleman, D. P., B. Hess, and M. S. P. Sansom. 2002. Analysis and evaluation of channel models: Simulations of alamethicin. Biophys. J. In press.83:2393-2407.
-
(2002)
Biophys. J.
, vol.83
, pp. 2393-2407
-
-
Tieleman, D.P.1
Hess, B.2
Sansom, M.S.P.3
-
99
-
-
0032951553
-
Alamethicin helices in a bilayer and in solution: Molecular dynamics simulations
-
Tieleman, D. P., M. S. P. Sansom, and H. J. C. Berendsen. 1999b. Alamethicin helices in a bilayer and in solution: Molecular dynamics simulations. Biophys. J. 76:40-49.
-
(1999)
Biophys. J.
, vol.76
, pp. 40-49
-
-
Tieleman, D.P.1
Sansom, M.S.P.2
Berendsen, H.J.C.3
-
100
-
-
0035312897
-
Electrostatics calculations: Recent methodological advances and applications to membranes
-
Tobias, D. J. 2001. Electrostatics calculations: Recent methodological advances and applications to membranes. Curr. Opin. Struct. Biol. 11:253-261.
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 253-261
-
-
Tobias, D.J.1
-
102
-
-
0027506299
-
Nicotinic acetylcholine receptor at 9 Å resolution
-
Unwin, N. 1993. Nicotinic acetylcholine receptor at 9 Å resolution. J. Mol. Biol. 229:1101-1124.
-
(1993)
J. Mol. Biol.
, vol.229
, pp. 1101-1124
-
-
Unwin, N.1
-
103
-
-
0028921479
-
Acetylcholine receptor channel imaged in the open state
-
Unwin, N. 1995. Acetylcholine receptor channel imaged in the open state. Nature. 373:37-43.
-
(1995)
Nature
, vol.373
, pp. 37-43
-
-
Unwin, N.1
-
104
-
-
0034731271
-
The Croonian Lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission
-
Unwin, N. 2000. The Croonian Lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission. Phil. Trans. Roy. Soc. Lond. B. 355:1813-1829.
-
(2000)
Phil. Trans. Roy. Soc. Lond. B
, vol.355
, pp. 1813-1829
-
-
Unwin, N.1
-
105
-
-
0026082583
-
Location of a threonine residue in the α-subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel
-
Villarroel, A., S. Herlitze, M. Koenen, and B. Sakmann. 1991. Location of a threonine residue in the α-subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel. Proc. R. Soc. Lond. B Biol. Sci. 243:69-74.
-
(1991)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.243
, pp. 69-74
-
-
Villarroel, A.1
Herlitze, S.2
Koenen, M.3
Sakmann, B.4
-
106
-
-
0343005873
-
Molecular dynamics simulations of a polyalanine octapeptide under Ewald boundary conditions: Influence of artificial periodicity on peptide conformation
-
Weber, W., P. H. Hunenberger, and J. A. McCammon. 2000. Molecular dynamics simulations of a polyalanine octapeptide under Ewald boundary conditions: Influence of artificial periodicity on peptide conformation. J. Phys. Chem. B. 104:3668-3675.
-
(2000)
J. Phys. Chem. B
, vol.104
, pp. 3668-3675
-
-
Weber, W.1
Hunenberger, P.H.2
McCammon, J.A.3
-
107
-
-
0031961956
-
Molecular dynamics simulation of an ion channel
-
Zhong, Q., Q. Jiang, P. B. Moore, D. M. Newns, and M. L. Klein. 1998a. Molecular dynamics simulation of an ion channel. Biophys. J. 74:3-10.
-
(1998)
Biophys. J.
, vol.74
, pp. 3-10
-
-
Zhong, Q.1
Jiang, Q.2
Moore, P.B.3
Newns, D.M.4
Klein, M.L.5
-
108
-
-
0032496397
-
Molecular dynamics study of the LS3 voltage-gated ion channel
-
Zhong, Q., P. B. Moore, D. M. Newns, and M. L. Klein. 1998b. Molecular dynamics study of the LS3 voltage-gated ion channel. FEBS Lett. 427:267-270.
-
(1998)
FEBS Lett.
, vol.427
, pp. 267-270
-
-
Zhong, Q.1
Moore, P.B.2
Newns, D.M.3
Klein, M.L.4
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