Cytosolic region of TM6 in P-glycoprotein: Topographical analysis and functional perturbation by site directed labeling

Biochemistry

Volumn 47, Issue 12, 2008, Pages 3615-3624

  Storm, Janet ^a   Modok, Szabolcs ^a   O'Mara, Megan L ^b   Tieleman, D Peter ^b   Kerr, Ian D ^c   Callaghan, Richard ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DRUG DELIVERY; MOLECULAR MECHANICS; ONCOLOGY;

DRUG EFFLUX PUMP; INTRACELLULAR DRUG ACCUMULATION; P-GLYCOPROTEIN;

PROTEINS;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; COUMARIN; CYSTEINE; GLYCOPROTEIN P; MALEIMIDE; NICARDIPINE; VANADIC ACID; VINBLASTINE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG BINDING; ENZYME ACTIVITY; GENE TRANSLOCATION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PURIFICATION;

BORON COMPOUNDS; COUMARINS; CYSTEINE; CYTOSOL; FLUORESCEINS; MALEIMIDES; MODELS, MOLECULAR; P-GLYCOPROTEIN; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY;

EID: 41149140334     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7023089     Document Type: Article

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