Mutational analysis of the P-glycoprotein first intracellular loop and flanking transmembrane domains

Biochemistry

Volumn 37, Issue 10, 1998, Pages 3337-3350

  Kwan, Tony ^a   Gros, Philippe ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; COMPLEMENTARY DNA; DNA POLYMERASE; GLYCOPROTEIN P; IONOPHORE; MUTANT PROTEIN; TACROLIMUS; VALINOMYCIN;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME SPECIFICITY; GENETIC RECOMBINATION; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA PRIMERS; DRUG RESISTANCE, MULTIPLE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS; P-GLYCOPROTEIN; PICHIA; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID;

SACCHAROMYCES CEREVISIAE;

EID: 0032502326     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972680x     Document Type: Article

References (63)

1. Raymond, M., Gros, P., Whiteway, M., and Thomas, D. Y. (1992) Science 256, 232-4.
2. Shustik, C., Dalton, W., and Gros, P. (1995) Mol. Aspects Med. 16, 1-78.
3. Hanna, M., and Gros, P. (1996) in Multidrug Resistance in Cancer Cells: Molecular, Biochemical, Physiological and Biological Aspects (Gupta, S., and Tsuruo, T., Eds.) pp 5-28, John Wiley and Sons, New York.
4. Ruetz, S., and Gros, P. (1994) Cell 77, 1071-81.
5. Schinkel, A. H., Smit, J. J., van Tellingen, O., Beijnen, J. H., Wagenaar, E., van Deemter, L., Mol, C. A., van der Valk, M. A., Robanus-Maandag, E. C., te Riele, H. P. et al. (1994) Cell 77, 491-502.
6. Vanhelvoort, A., Smith, A. J., Sprang, H., Fritzsche, I., Schinkel, A. H., Borst, P., and Vanmeer, G. (1996) Cell 87, 507-517.
7. Kuchler, K., Sterne, R. H., and Thorner, J. (1989) EMBO J. 8, 3973-84.
8. Foote, S. J., Thompson, J. K., Cowman, A. F., and Kemp, D. J. (1989) Cell 57, 921-30.
9. Cole, S. P., Bhardwaj, G., Gerlach, J. H., Mackie, J. E., Grant, C. E., Almquist, K. C., Stewart, A. J., Kurz, E. U., Duncan, A. M., and Deeley, R. G. (1992) Science 258, 1650-4.
10. Shen, H. X., Paul, S., Breuninaer, L. M., Ciaccio, P. J., Laing, N. M., Helt, M., Tew, K. D., and Kruh, G. D. (1996) Biochemistry 35, 5719-5725.
11. Deverson, E. V., Gow, I. R., Coadwell, W. J., Monaco, J. J., Butcher, G. W., and Howard, J. C. (1990) Nature 348, 738- 41.
12. Monaco, J. J., Cho, S., and Attaya, M. (1990) Science 250, 1723-6.
13. Spies, T., Cerundolo, V., Colonna, M., Cresswell, P., Townsend, A., and DeMars, R. (1992) Nature 355, 644-6.
14. Trowsdale, J., Hanson, I., Mockridge, I., Beck, S., Townsend, A., and Kelly, A. (1990) Nature 348, 741-4.
15. Riordan, J. R., Rommens, J. M., Kerem, B., Alon, N., Rozmahel, R., Grzelczak, Z., Zielenski, J., Lok, S., Plavsic, N., Chou, J. L. et al. (1989) Science 245, 1066-73.
16. van Doorninck, J. H., French, P. J., Verbcek, E., Peters, R. H., Morreau, H., Bijman, J., and Scholte, B. J. (1995) EMBO J. 14, 4403-11.
17. Ruetz, S., Brault, M., Kast, C., Hemenway, C., Heitman, J., Grant, C. E., Cole, S. P., Deeley, R. G., and Gres, P. (1996) J. Biol. Chem. 271, 4154-60.
18. Ruetz, S., Delling, U., Brault, M., Schurr, E., and Gros, P. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 9942-7.
19. Volkman, S. K., Cowman, A. F., and Wirth, D. F. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 8921-8925.
20. Gros, P., Croop, J., and Housman, D. (1986) Cell 47, 371- 80.
21. Chen, C. J., Chin, J. E., Ueda, K., Clark, D. P., Pastan, I., Gottesman, M. M., and Roninson, I. B. (1986) Cell 4, 381- 9.
22. Yoshimura, A., Kuwazuru, Y., Sumizawa, T., Ichikawa, M., Ikeda, S., Uda, T., and Akiyama, S. (1989) J. Biol. Chem. 264, 16282-91.
23. Kartner, N., Evernden-Porelle, D., Bradley, G., and Ling, V. (1985) Nature 316, 820-3.
24. Kast, C., Canfield, V., Levenson, R., and Gros, P. (1996) J. Biol. Chem. 271, 9240-9248.
25. Kast, C., Canfield, V., Levenson, R., and Gros, P. (1995) Biochemistry 34, 4402-11.
26. Loo, T. W., and Clarke, D. M. (1995) J. Biol. Chem. 270 843-8.
27. Raviv, Y., Pollard, H. B., Bruggemann, E. P., Pastan, I., and Gottesman, M. M. (1990) J. Biol. Chem. 265, 3975-80.
28. Greenberger, L. M. (1993) J. Biol. Chem. 268, 11417-25.
29. Devine, S. E., Ling, V., and Melera, P. W. (1992) Proc Natl. Acad. Sci. U.S.A. 89, 4564-8.
30. Loo, T. W., and Clarke, D. M. (1994) Biochemistry 33 14049-57.
31. Loo, T. W., and Clarke, D. M. (1993) J. Biol. Chem. 268, 3143-9.
32. Loo, T. W., and Clarke, D. M. (1993) J. Biol. Chem. 268, 19965-72.
33. Gros, P., Dhir, R., Croop, J., and Talbot, F. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 7289-93.
34. Dhir, R., Grizzuti, K., Kajiji, S., and Gros, P. (1993) Biochemistry 32, 9492-9.
35. Loo, T. W., and Clarke, D. M. (1995) J. Biol. Chem. 270, 22957-61.
36. Homolya, L., Hollo, Z., Germann, U. A., Pastan, I., Gottesman M. M., and Sarkadi, B. (1993) J. Biol. Chem. 268, 21 93-6.
37. Rao, U. S., and Scarborough, G. A. (1994) Mol. Pharmacol. 45, 773-6.
38. Loo, T. W., and Clarke, D. M. (1994) J. Biol. Chem. 269, 7243-8.
39. Choi, K. H., Chen, C. J., Kriegler, M., and Roninson, I. B. (1988) Cell 53, 519-29.
40. Safa, A. R., Stern, R. K., Choi, K., Agresti, M., Tam I., Mehta, N. D., and Roninson, I. B. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 7225-9.
41. Rao, U. S. (1995) J. Biol. Chem. 270, 6686-90.
42. Beaudet, L., and Gros, P. (1995) J. Biol. Chem. 270, 17159- 70.
43. Muller, M., Bakos, E., Welker, H., Varadi, A., Germann, U. A., Gottesman, M. M., Morse, B. S., Roninson, I. B., and Sarkadi, B. (1996) J. Biol. Chem. 271, 1877-83.
44. Momburg, F., Armandola, E. A., Post, M., and Hammerlins, G. J. (1996) J. Immunol. 156, 1756-1763.
45. Currier, S. J., Kane, S. E., Willingham, M. C., Cardarelli, C. O., Pastan, I., and Gottesman, M. M. (1992) J. Biol. Chem. 267, 25153-9.
46. Cotten, J. F., Ostedgaard, L. S., Carson, M. R., and Welsh, M. J. (1996) J. Biol. Chem. 271, 21279-21284.
47. Seibert, F. S., Linsdell, P., Loo, T. W., Hanrahan, J. W., Clarke, D. M., and Riordan, J. R. (1996) J. Biol. Chem. 271, 15139- 45.
48. Devault, A., and Gros, P. (1990) Mol. Cell Biol. 10, 1652- 63.
49. Ruetz, S., and Gros, P. (1994) J. Biol. Chem. 269, 12277- 84.
50. Spec, J. H., de Vos, W. M., and Kuipers, O. P. (1993) Nucleic Acids Res. 21, 777-8.
51. Holton, T. A., and Graham, M. W. (1991) Nucleic Acids Res. 19, 1156.
52. Ishioka, C., Frebourg, T., Van, Y. X., Vidal, M., Friend,S. H., Schmidt, S., and Iggo, R. (1993) Nature Genet. 5, 124-9.
53. Raymond, M., Ruetz, S., Thomas, D. Y., and Gros, P. (1994) Mol. Cell. Biol. 14, 277-86.
54. Perlin, D. S., Harris, S. L., Seto-Young, D., and Haber, J. E. (1989) J. Biol. Chem. 264, 21857-64.
55. Van Veldhoven, P. P., and Mannaerts, G. P. (1987) Anal. Biochem. 161, 45-8.
56. Kuchler, K., and Thomer, J. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 2302-6.
57. Beaudet, L., Urbatsch, I. L., and Gros, P. (1997) Methods Enzymol., in press.
58. Loo, T. W., and Clarke, D. M. (1996) J. Biol. Chem. 271, 15414-9.
59. Myers, R. M., Lerman, L. S., and Maniatis, T. (1985) Science 229, 242-7.
60. Schaaper, R. M. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 8126-30.
61. Anderon, M. P., Gregory, R. J., Thompson S. Souza, D. W., Paul, S., Mulligan, R. C. Smith, A. E., and Welsh, M. J. (1991) Science 253, 202-5.
62. Hanna M., Brault, M., Kwan, T., Kast, C., and Gros, P. (1996) Biochemistry 35, 3625-35.
63. Schurr, E., Raymond, M., Bell, J. C., and Gros, P. (1989) Cancer Res 49, 2729-33.