메뉴 건너뛰기




Volumn 263, Issue 1, 2008, Pages 14-25

TRAIL and cancer therapy

Author keywords

Apoptosis; Cancer; Kinases; Therapy; TRAIL

Indexed keywords

1 [5 HYDROXY 2 (2 THIENYL) 4 QUINAZOLINYLAMINO] 3 METHYL 2,5 PYRROLEDIONE; BORTEZOMIB; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUOROURACIL; GEFITINIB; GOSSYPOL; HISTONE DEACETYLASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; LEXATUMUMAB; MAPATUMUMAB; PROTEIN BCL 2; SORAFENIB; TOPOTECAN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

EID: 41049112098     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.02.003     Document Type: Review
Times cited : (155)

References (85)
  • 1
    • 13344285339 scopus 로고
    • Identification and characterization of a new member of the TNF family that induces apoptosis
    • Wiley S.R., Schooley K., Smolak P.J., Din W.S., Huang C.P., Nicholl J.K., et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 6 (1995) 673-682
    • (1995) Immunity , vol.6 , pp. 673-682
    • Wiley, S.R.1    Schooley, K.2    Smolak, P.J.3    Din, W.S.4    Huang, C.P.5    Nicholl, J.K.6
  • 2
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti R.M., Marsters S.A., Ruppert S., Donahue C.J., Moore A., and Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 271 (1996) 12687-12690
    • (1996) J. Biol. Chem. , vol.271 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5    Ashkenazi, A.6
  • 3
    • 0031905817 scopus 로고    scopus 로고
    • Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage
    • Mariani S.M., and Krammer P.H. Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage. Eur. J. Immonol. 28 (1998) 973-982
    • (1998) Eur. J. Immonol. , vol.28 , pp. 973-982
    • Mariani, S.M.1    Krammer, P.H.2
  • 4
    • 0037273848 scopus 로고    scopus 로고
    • Apo2L/TRAIL and its death and decoy receptors
    • LeBlanc H.N., and Ashkenazi A. Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ. 10 (2003) 66-75
    • (2003) Cell Death Differ. , vol.10 , pp. 66-75
    • LeBlanc, H.N.1    Ashkenazi, A.2
  • 5
    • 16644372319 scopus 로고    scopus 로고
    • Following a TRAIL: update on a ligand and its five receptors
    • Kimberley F.C., and Screaton G.R. Following a TRAIL: update on a ligand and its five receptors. Cell Res. 14 (2004) 359-372
    • (2004) Cell Res. , vol.14 , pp. 359-372
    • Kimberley, F.C.1    Screaton, G.R.2
  • 7
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • Degli-Esposti M.A., Dougall W.C., Smolak P.J., Waugh J.Y., Smith C.A., and Goodwin R.G. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 7 (1997) 813-820
    • (1997) Immunity , vol.7 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 9
    • 27544432516 scopus 로고    scopus 로고
    • Nonapoptotic functions of FADD-binding death receptors and their signaling molecules
    • Park S.M., Schickel R., and Peter M.E. Nonapoptotic functions of FADD-binding death receptors and their signaling molecules. Curr. Opion Cell Biol. 17 (2005) 1-7
    • (2005) Curr. Opion Cell Biol. , vol.17 , pp. 1-7
    • Park, S.M.1    Schickel, R.2    Peter, M.E.3
  • 10
    • 0036467427 scopus 로고    scopus 로고
    • Increased susceptibility to tumor initiation and metastasis in TNF-apoptosis-inducing ligand-deficient mice
    • Cretney E., Takeda K., Yagita H., Glaccum M., Peschon J.J., and Smyth M.J. Increased susceptibility to tumor initiation and metastasis in TNF-apoptosis-inducing ligand-deficient mice. J. Immunol. 168 (2002) 1356-1361
    • (2002) J. Immunol. , vol.168 , pp. 1356-1361
    • Cretney, E.1    Takeda, K.2    Yagita, H.3    Glaccum, M.4    Peschon, J.J.5    Smyth, M.J.6
  • 12
    • 33745854287 scopus 로고    scopus 로고
    • The role of TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology
    • Zauli G., and Secchiero P. The role of TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology. Cytokine Growth Factor Rev. 17 (2006) 245-257
    • (2006) Cytokine Growth Factor Rev. , vol.17 , pp. 245-257
    • Zauli, G.1    Secchiero, P.2
  • 13
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: critical control points
    • Danial N.N., and Korsmeyer S.J. Cell death: critical control points. Cell 116 (2004) 205-219
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 14
    • 25144489068 scopus 로고    scopus 로고
    • Overview of cell death signaling pathways
    • Jin Z., and El-Deiry W.S. Overview of cell death signaling pathways. Cancer Biol. Ther. 4 (2005) 139-163
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 139-163
    • Jin, Z.1    El-Deiry, W.S.2
  • 16
    • 0036859738 scopus 로고    scopus 로고
    • Defining characteristics of Types I and II apoptotic cells in response to TRAIL
    • Ozoren N., and El-Deiry W.S. Defining characteristics of Types I and II apoptotic cells in response to TRAIL. Neoplasia. 4 (2002) 551-557
    • (2002) Neoplasia. , vol.4 , pp. 551-557
    • Ozoren, N.1    El-Deiry, W.S.2
  • 17
    • 85047692516 scopus 로고    scopus 로고
    • Signaling pathways of the TNF superfamily: a double-edged sword
    • Aggarwal B.B. Signaling pathways of the TNF superfamily: a double-edged sword. Nat. Rev. Immunol. 3 (2003) 745-756
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 745-756
    • Aggarwal, B.B.1
  • 18
    • 28844441555 scopus 로고    scopus 로고
    • Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
    • Varfolomeev E., Maecker H., Sharp D., Lawrence D., Renz M., Vucic D., and Ashkenazi A. Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J. Biol. Chem. 280 (2005) 40599-40608
    • (2005) J. Biol. Chem. , vol.280 , pp. 40599-40608
    • Varfolomeev, E.1    Maecker, H.2    Sharp, D.3    Lawrence, D.4    Renz, M.5    Vucic, D.6    Ashkenazi, A.7
  • 19
    • 0034136792 scopus 로고    scopus 로고
    • The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis
    • Meng III R.D., McDonald E.R., Sheikh M.S., Fornace Jr. A.J., and El-Deiry W.S. The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis. Mol. Ther. 1 (2000) 130-144
    • (2000) Mol. Ther. , vol.1 , pp. 130-144
    • Meng III, R.D.1    McDonald, E.R.2    Sheikh, M.S.3    Fornace Jr., A.J.4    El-Deiry, W.S.5
  • 20
    • 35348948380 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins
    • Werneburg N.W., Guicciardi M.E., Bronk S.F., Kaufmann S.H., and Gores G.J. Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins. J. Biol. Chem. 282 39 (2007) 28960-28970
    • (2007) J. Biol. Chem. , vol.282 , Issue.39 , pp. 28960-28970
    • Werneburg, N.W.1    Guicciardi, M.E.2    Bronk, S.F.3    Kaufmann, S.H.4    Gores, G.J.5
  • 22
    • 29144496895 scopus 로고    scopus 로고
    • Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis
    • Clancy L., Mruk K., Archer K., Woelfel M., Mongkolsapaya J., Screaton G., et al. Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proc. Natl. Acad. Sci. USA 102 (2005) 18099-18104
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 18099-18104
    • Clancy, L.1    Mruk, K.2    Archer, K.3    Woelfel, M.4    Mongkolsapaya, J.5    Screaton, G.6
  • 24
    • 34948894931 scopus 로고    scopus 로고
    • Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
    • Wagner K.W., Punnoose E.A., Januario T., Lawrence D.A., Pitti R.M., Lancaster K., et al. Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat. Med. 13 (2007) 1070-1077
    • (2007) Nat. Med. , vol.13 , pp. 1070-1077
    • Wagner, K.W.1    Punnoose, E.A.2    Januario, T.3    Lawrence, D.A.4    Pitti, R.M.5    Lancaster, K.6
  • 25
    • 0037067678 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells
    • Xiao C., Yang B.F., Asadi N., Beguinot F., and Hao C. Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells. J. Biol. Chem. 277 (2002) 25020-25025
    • (2002) J. Biol. Chem. , vol.277 , pp. 25020-25025
    • Xiao, C.1    Yang, B.F.2    Asadi, N.3    Beguinot, F.4    Hao, C.5
  • 26
    • 34547123570 scopus 로고    scopus 로고
    • Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells
    • Song J.H., Tse M.C., Bellail A., Phuphanich S., Khuri F., Kneteman N.M., and Hao C. Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells. Cancer Res. 67 (2007) 6946-6955
    • (2007) Cancer Res. , vol.67 , pp. 6946-6955
    • Song, J.H.1    Tse, M.C.2    Bellail, A.3    Phuphanich, S.4    Khuri, F.5    Kneteman, N.M.6    Hao, C.7
  • 27
    • 0036131142 scopus 로고    scopus 로고
    • Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
    • LeBlanc H., Lawrence D., Varfolomeev E., Totpal K., Morlan J., Schow P., et al. Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax. Nat. Med. 8 (2002) 274-281
    • (2002) Nat. Med. , vol.8 , pp. 274-281
    • LeBlanc, H.1    Lawrence, D.2    Varfolomeev, E.3    Totpal, K.4    Morlan, J.5    Schow, P.6
  • 28
    • 0037018277 scopus 로고    scopus 로고
    • Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression
    • Fulda S., Meyer E., and Debatin K.M. Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression. Oncogene 21 (2002) 2283-2294
    • (2002) Oncogene , vol.21 , pp. 2283-2294
    • Fulda, S.1    Meyer, E.2    Debatin, K.M.3
  • 29
    • 12444288591 scopus 로고    scopus 로고
    • Type I and type II reactions in TRAIL-induced apoptosis - results from dose-response studies
    • Rudner J., Jendrossek V., Lauber K., Daniel P.T., Wesselborg S., and Belka C. Type I and type II reactions in TRAIL-induced apoptosis - results from dose-response studies. Oncogene 24 (2005) 130-140
    • (2005) Oncogene , vol.24 , pp. 130-140
    • Rudner, J.1    Jendrossek, V.2    Lauber, K.3    Daniel, P.T.4    Wesselborg, S.5    Belka, C.6
  • 30
    • 2442663096 scopus 로고    scopus 로고
    • Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells
    • Taniai M., Grambihler A., Higuchi H., Werneburg N., Bronk S.F., Farrugia D.J., et al. Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells. Cancer Res. 64 (2004) 3517-3524
    • (2004) Cancer Res. , vol.64 , pp. 3517-3524
    • Taniai, M.1    Grambihler, A.2    Higuchi, H.3    Werneburg, N.4    Bronk, S.F.5    Farrugia, D.J.6
  • 31
    • 33646846666 scopus 로고    scopus 로고
    • Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis
    • Clohessy J.G., Zhuang J., de Boer J., Gil-Gómez G., and Brady H.J. Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis. J. Biol. Chem. 281 (2006) 5750-5759
    • (2006) J. Biol. Chem. , vol.281 , pp. 5750-5759
    • Clohessy, J.G.1    Zhuang, J.2    de Boer, J.3    Gil-Gómez, G.4    Brady, H.J.5
  • 33
    • 2342495721 scopus 로고    scopus 로고
    • Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway
    • Wang Y., Engels I.H., Knee D.A., Nasoff M., Deveraux Q.L., and Quon K.C. Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway. Cancer Cell. 5 (2004) 501-512
    • (2004) Cancer Cell. , vol.5 , pp. 501-512
    • Wang, Y.1    Engels, I.H.2    Knee, D.A.3    Nasoff, M.4    Deveraux, Q.L.5    Quon, K.C.6
  • 34
    • 34347246278 scopus 로고    scopus 로고
    • Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death
    • Ricci M.S., Kim S.H., Ogi K., Plastaras J.P., Ling J., Wang W., et al. Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. Cancer Cell. 12 (2007) 66-80
    • (2007) Cancer Cell. , vol.12 , pp. 66-80
    • Ricci, M.S.1    Kim, S.H.2    Ogi, K.3    Plastaras, J.P.4    Ling, J.5    Wang, W.6
  • 35
    • 0030762815 scopus 로고    scopus 로고
    • An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    • Pan G., Ni J., Wei Y.F., Yu G., Gentz R., and Dixit V.M. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 277 (1997) 815-818
    • (1997) Science , vol.277 , pp. 815-818
    • Pan, G.1    Ni, J.2    Wei, Y.F.3    Yu, G.4    Gentz, R.5    Dixit, V.M.6
  • 36
    • 2542611366 scopus 로고    scopus 로고
    • Oncogenic Ras sensitizes normal human cells to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis
    • Nesterov A., Nikrad M., Johnson T., and Kraft A.S. Oncogenic Ras sensitizes normal human cells to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis. Cancer Res. 64 (2004) 3922-3927
    • (2004) Cancer Res. , vol.64 , pp. 3922-3927
    • Nesterov, A.1    Nikrad, M.2    Johnson, T.3    Kraft, A.S.4
  • 37
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H., Miller R.E., Ariail K., Gliniak K.B., Griffith T.S., Kubin M., et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med. 5 (1999) 157-163
    • (1999) Nat. Med. , vol.5 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3    Gliniak, K.B.4    Griffith, T.S.5    Kubin, M.6
  • 39
    • 34547819299 scopus 로고    scopus 로고
    • The promise of TRAIL-potential and risks of a novel anticancer therapy
    • Koschny R., Walczak H., and Ganten T.M. The promise of TRAIL-potential and risks of a novel anticancer therapy. J. Mol. Med. 85 (2007) 923-935
    • (2007) J. Mol. Med. , vol.85 , pp. 923-935
    • Koschny, R.1    Walczak, H.2    Ganten, T.M.3
  • 40
    • 21044441651 scopus 로고    scopus 로고
    • HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo
    • Pukac L., Kanakaraj P., Humphreys R., Alderson R., Bloom M., Sung C., et al. HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo. Br. J. Cancer 92 (2005) 1430-1441
    • (2005) Br. J. Cancer , vol.92 , pp. 1430-1441
    • Pukac, L.1    Kanakaraj, P.2    Humphreys, R.3    Alderson, R.4    Bloom, M.5    Sung, C.6
  • 41
    • 33646403907 scopus 로고    scopus 로고
    • Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo
    • Zeng Y., Wu X.X., Fiscella M., Shimada O., Humphreys R., Albert V., and Kakehi Y. Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo. Int. J. Oncol. 28 (2006) 421-430
    • (2006) Int. J. Oncol. , vol.28 , pp. 421-430
    • Zeng, Y.1    Wu, X.X.2    Fiscella, M.3    Shimada, O.4    Humphreys, R.5    Albert, V.6    Kakehi, Y.7
  • 42
    • 24944458177 scopus 로고    scopus 로고
    • Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death
    • Georgakis G.V., Li Y., Humphreys R., Andreeff M., O'Brien S., Younes M., Carbone A., Albert V., and Younes A. Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death. Br. J. Haematol. 130 (2005) 501-510
    • (2005) Br. J. Haematol. , vol.130 , pp. 501-510
    • Georgakis, G.V.1    Li, Y.2    Humphreys, R.3    Andreeff, M.4    O'Brien, S.5    Younes, M.6    Carbone, A.7    Albert, V.8    Younes, A.9
  • 43
    • 33747829837 scopus 로고    scopus 로고
    • Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo
    • Marini P., Denzinger S., Schiller D., Kauder S., Welz S., Humphreys R., et al. Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo. Oncogene 25 (2006) 5145-5154
    • (2006) Oncogene , vol.25 , pp. 5145-5154
    • Marini, P.1    Denzinger, S.2    Schiller, D.3    Kauder, S.4    Welz, S.5    Humphreys, R.6
  • 46
    • 12544255082 scopus 로고    scopus 로고
    • Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling
    • Kelley R.F., Totpal K., Lindstrom S.H., Mathieu M., Billeci K., Deforge L., Pai R., Hymowitz S.G., and Ashkenazi A. Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling. J. Biol. Chem. 280 (2005) 2205-2212
    • (2005) J. Biol. Chem. , vol.280 , pp. 2205-2212
    • Kelley, R.F.1    Totpal, K.2    Lindstrom, S.H.3    Mathieu, M.4    Billeci, K.5    Deforge, L.6    Pai, R.7    Hymowitz, S.G.8    Ashkenazi, A.9
  • 47
    • 29244483111 scopus 로고    scopus 로고
    • TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies
    • MacFarlane M., Kohlhaas S.L., Sutcliffe M.J., Dyer M.J., and Cohen G.M. TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies. Cancer Res. 65 (2005) 11265-11270
    • (2005) Cancer Res. , vol.65 , pp. 11265-11270
    • MacFarlane, M.1    Kohlhaas, S.L.2    Sutcliffe, M.J.3    Dyer, M.J.4    Cohen, G.M.5
  • 49
    • 3342950457 scopus 로고    scopus 로고
    • Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL
    • Abou El Hassan M.A., Mastenbroek D.C., Gerritsen W.R., Giaccone G., and Kruyt F.A. Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL. Br. J. Cancer 91 (2004) 171-177
    • (2004) Br. J. Cancer , vol.91 , pp. 171-177
    • Abou El Hassan, M.A.1    Mastenbroek, D.C.2    Gerritsen, W.R.3    Giaccone, G.4    Kruyt, F.A.5
  • 50
    • 25144433291 scopus 로고    scopus 로고
    • Radiotherapy sensitization by tumor-specific TRAIL gene targeting improves survival of mice bearing human non-small cell lung cancer
    • Zhang X., Cheung R.M., Komaki R., Fang B., and Chang J.Y. Radiotherapy sensitization by tumor-specific TRAIL gene targeting improves survival of mice bearing human non-small cell lung cancer. Clin. Cancer Res. 11 (2005) 6657-6668
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6657-6668
    • Zhang, X.1    Cheung, R.M.2    Komaki, R.3    Fang, B.4    Chang, J.Y.5
  • 51
    • 0035394722 scopus 로고    scopus 로고
    • Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers
    • Shin M.S., Kim H.S., Lee S.H., Park W.S., Kim S.Y., Park J.Y., et al. Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers. Cancer Res. 61 (2001) 4942-4946
    • (2001) Cancer Res. , vol.61 , pp. 4942-4946
    • Shin, M.S.1    Kim, H.S.2    Lee, S.H.3    Park, W.S.4    Kim, S.Y.5    Park, J.Y.6
  • 52
    • 0001130662 scopus 로고    scopus 로고
    • Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers
    • Lee S.H., Shin M.S., Kim H.S., Lee H.K., Park W.S., Kim S.Y., et al. Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers. Cancer Res. 59 (1999) 5683-5686
    • (1999) Cancer Res. , vol.59 , pp. 5683-5686
    • Lee, S.H.1    Shin, M.S.2    Kim, H.S.3    Lee, H.K.4    Park, W.S.5    Kim, S.Y.6
  • 54
    • 3142735020 scopus 로고    scopus 로고
    • Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand cooperates with chemotherapy to inhibit orthotopic lung tumor growth and improve survival
    • Jin H., Yang R., Fong S., Totpal K., Lawrence D., Zheng Z., et al. Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand cooperates with chemotherapy to inhibit orthotopic lung tumor growth and improve survival. Cancer Res 64 (2004) 4900-4905
    • (2004) Cancer Res , vol.64 , pp. 4900-4905
    • Jin, H.1    Yang, R.2    Fong, S.3    Totpal, K.4    Lawrence, D.5    Zheng, Z.6
  • 56
    • 0034899716 scopus 로고    scopus 로고
    • Shared pathways: death receptors and cytotoxic drugs in cancer therapy
    • Petak I., and Houghton J.A. Shared pathways: death receptors and cytotoxic drugs in cancer therapy. Pathol. Oncol. Res. 7 (2001) 95-106
    • (2001) Pathol. Oncol. Res. , vol.7 , pp. 95-106
    • Petak, I.1    Houghton, J.A.2
  • 57
    • 14844288360 scopus 로고    scopus 로고
    • Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy
    • Van Geelen C.M., de Vries E.G., and de Jong S. Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy. Drug. Resist. Updat. 7 (2004) 345-358
    • (2004) Drug. Resist. Updat. , vol.7 , pp. 345-358
    • Van Geelen, C.M.1    de Vries, E.G.2    de Jong, S.3
  • 59
    • 34147189664 scopus 로고    scopus 로고
    • Enhancement of death receptor 4 mediated apoptosis and cytotoxicity in renal cell carcinoma cells by subtoxic concentrations of doxorubicin
    • Jin X., Wu X.X., Abdel-Muneem Nouh M.A., and Kakehi Y. Enhancement of death receptor 4 mediated apoptosis and cytotoxicity in renal cell carcinoma cells by subtoxic concentrations of doxorubicin. J. Urol. 177 (2007) 1894-1899
    • (2007) J. Urol. , vol.177 , pp. 1894-1899
    • Jin, X.1    Wu, X.X.2    Abdel-Muneem Nouh, M.A.3    Kakehi, Y.4
  • 60
    • 0042710263 scopus 로고    scopus 로고
    • Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells
    • Deeb D., Xu Y.X., Jiang H., Gao X., Janakiraman N., Chapman R.A., and Gautam S.C. Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells. Mol. Cancer Ther. 2 (2003) 95-103
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 95-103
    • Deeb, D.1    Xu, Y.X.2    Jiang, H.3    Gao, X.4    Janakiraman, N.5    Chapman, R.A.6    Gautam, S.C.7
  • 61
    • 1642576201 scopus 로고    scopus 로고
    • Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol
    • Fulda S., and Debatin K.M. Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol. Cancer Res. 64 (2004) 337-346
    • (2004) Cancer Res. , vol.64 , pp. 337-346
    • Fulda, S.1    Debatin, K.M.2
  • 62
    • 10644246821 scopus 로고    scopus 로고
    • Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
    • Delmas D., Rébé C., Micheau O., Athias A., Gambert P., Grazide S., Laurent G., Latruffe N., and Solary E. Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene 23 (2004) 8979-8986
    • (2004) Oncogene , vol.23 , pp. 8979-8986
    • Delmas, D.1    Rébé, C.2    Micheau, O.3    Athias, A.4    Gambert, P.5    Grazide, S.6    Laurent, G.7    Latruffe, N.8    Solary, E.9
  • 63
    • 34648813877 scopus 로고    scopus 로고
    • Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells
    • Shankar S., Siddiqui I., and Srivastava R.K. Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells. Mol. Cell Biochem. 304 (2007) 273-285
    • (2007) Mol. Cell Biochem. , vol.304 , pp. 273-285
    • Shankar, S.1    Siddiqui, I.2    Srivastava, R.K.3
  • 64
    • 0034691130 scopus 로고    scopus 로고
    • Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
    • Wang J.-L., Liu D., Zhang Z.-J., Shan S., Han X., Srinivasula S.M., et al. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proc. Natl. Acad. Sci. USA 97 (2000) 7124-7129
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7124-7129
    • Wang, J.-L.1    Liu, D.2    Zhang, Z.-J.3    Shan, S.4    Han, X.5    Srinivasula, S.M.6
  • 65
    • 11144230279 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells
    • Sinicrope F.A., Penington R.C., and Tang X.M. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells. Clin. Cancer Res. 10 (2004) 8284-8292
    • (2004) Clin. Cancer Res. , vol.10 , pp. 8284-8292
    • Sinicrope, F.A.1    Penington, R.C.2    Tang, X.M.3
  • 66
    • 33751542949 scopus 로고    scopus 로고
    • Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
    • Yeow W.S., Baras A., Chua A., Nguyen D.M., Sehgal S.S., Schrump D.S., and Nguyen D.M. Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J. Thorac. Cardiovasc. Surg. 132 (2006) 1356-1362
    • (2006) J. Thorac. Cardiovasc. Surg. , vol.132 , pp. 1356-1362
    • Yeow, W.S.1    Baras, A.2    Chua, A.3    Nguyen, D.M.4    Sehgal, S.S.5    Schrump, D.S.6    Nguyen, D.M.7
  • 67
    • 0036341291 scopus 로고    scopus 로고
    • Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
    • Fulda S., Wick W., Weller M., and Debatin K.M. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat. Med. 8 (2002) 808-815
    • (2002) Nat. Med. , vol.8 , pp. 808-815
    • Fulda, S.1    Wick, W.2    Weller, M.3    Debatin, K.M.4
  • 68
    • 4444243683 scopus 로고    scopus 로고
    • A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death
    • Li L., Thomas R.M., Suzuki H., De Brabander J.K., Wang X., and Harran P.G. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 305 (2004) 1471-1474
    • (2004) Science , vol.305 , pp. 1471-1474
    • Li, L.1    Thomas, R.M.2    Suzuki, H.3    De Brabander, J.K.4    Wang, X.5    Harran, P.G.6
  • 69
    • 34447294826 scopus 로고    scopus 로고
    • TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib
    • Voortman J., Resende T.P., Abou El Hassan M.A., Giaccone G., and Kruyt F.A. TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib. Mol. Cancer Ther. 6 (2007) 2103-2112
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 2103-2112
    • Voortman, J.1    Resende, T.P.2    Abou El Hassan, M.A.3    Giaccone, G.4    Kruyt, F.A.5
  • 70
    • 34250332128 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells
    • Liu X., Yue P., Chen S., Hu L., Lonial S., Khuri F.R., and Sun S.Y. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells. Cancer Res. 67 (2007) 4981-4988
    • (2007) Cancer Res. , vol.67 , pp. 4981-4988
    • Liu, X.1    Yue, P.2    Chen, S.3    Hu, L.4    Lonial, S.5    Khuri, F.R.6    Sun, S.Y.7
  • 72
    • 35948980027 scopus 로고    scopus 로고
    • Canonical nuclear factor {kappa}B pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL
    • Romagnoli M., Desplanques G., Maiga S., Legouill S., Dreano M., Bataille R., and Barille-Nion S. Canonical nuclear factor {kappa}B pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL. Clin. Cancer Res. 13 (2007) 6010-6018
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6010-6018
    • Romagnoli, M.1    Desplanques, G.2    Maiga, S.3    Legouill, S.4    Dreano, M.5    Bataille, R.6    Barille-Nion, S.7
  • 73
    • 35648993596 scopus 로고    scopus 로고
    • Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization
    • Meng X.W., Lee S.D., Dai H., Loegering D., Yu C., Flatten K., et al. Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization. J. Biol. Chem. 282 (2007) 29831-29846
    • (2007) J. Biol. Chem. , vol.282 , pp. 29831-29846
    • Meng, X.W.1    Lee, S.D.2    Dai, H.3    Loegering, D.4    Yu, C.5    Flatten, K.6
  • 74
    • 35148900795 scopus 로고    scopus 로고
    • The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation
    • Rosato R.R., Almenara J.A., Coe S., and Grant S. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation. Cancer Res. 67 (2007) 9490-9500
    • (2007) Cancer Res. , vol.67 , pp. 9490-9500
    • Rosato, R.R.1    Almenara, J.A.2    Coe, S.3    Grant, S.4
  • 75
    • 22544441630 scopus 로고    scopus 로고
    • Z1839 (Gefitinib,'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma
    • Teraishi F., Kagawa S., Watanabe T., Tango Y., Kawashima T., Umeoka T., et al. Z1839 (Gefitinib,'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma. FEBS Lett. 549 (2005) 4069-4075
    • (2005) FEBS Lett. , vol.549 , pp. 4069-4075
    • Teraishi, F.1    Kagawa, S.2    Watanabe, T.3    Tango, Y.4    Kawashima, T.5    Umeoka, T.6
  • 76
    • 33847726589 scopus 로고    scopus 로고
    • Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression
    • Shrader M., Pino M.S., Lashinger L., Bar-Eli M., Adam L., Dinney C.P., and McConkey D.J. Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Cancer Res. 67 (2007) 1430-1435
    • (2007) Cancer Res. , vol.67 , pp. 1430-1435
    • Shrader, M.1    Pino, M.S.2    Lashinger, L.3    Bar-Eli, M.4    Adam, L.5    Dinney, C.P.6    McConkey, D.J.7
  • 77
    • 0035845541 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species
    • Ruefli A.A., Ausserlechner M.J., Bernhard D., Sutton V.R., Tainton K.M., Kofler R., Smyth M.J., and Johnstone R.W. The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. Proc. Natl. Acad. Sci. USA 98 (2001) 10833-10838
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10833-10838
    • Ruefli, A.A.1    Ausserlechner, M.J.2    Bernhard, D.3    Sutton, V.R.4    Tainton, K.M.5    Kofler, R.6    Smyth, M.J.7    Johnstone, R.W.8
  • 78
    • 13444274622 scopus 로고    scopus 로고
    • Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
    • Insinga A., Monestiroli S., Ronzoni S., Gelmetti V., Marches F., Viale A., et al. Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nat. Med. 11 (2005) 71-76
    • (2005) Nat. Med. , vol.11 , pp. 71-76
    • Insinga, A.1    Monestiroli, S.2    Ronzoni, S.3    Gelmetti, V.4    Marches, F.5    Viale, A.6
  • 80
    • 2942584501 scopus 로고    scopus 로고
    • Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells
    • Rosato R.R., Almenara J.A., Dai Y., and Grant S. Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells. Mol. Cancer Ther. 2 (2003) 273-1284
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 273-1284
    • Rosato, R.R.1    Almenara, J.A.2    Dai, Y.3    Grant, S.4
  • 81
    • 38449087548 scopus 로고    scopus 로고
    • Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo
    • Zopf S., Neureiter D., Bouralexis S., Abt T., Glaser K.B., Okamoto K., et al. Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo. Int. J. Oncol. 31 (2007) 391-1402
    • (2007) Int. J. Oncol. , vol.31 , pp. 391-1402
    • Zopf, S.1    Neureiter, D.2    Bouralexis, S.3    Abt, T.4    Glaser, K.B.5    Okamoto, K.6
  • 82
    • 33847167668 scopus 로고    scopus 로고
    • A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer
    • Herbst R.S., Mendelson D.S., Ebbinghaus S., Gordon M.S., O'Dwyer P., Lieberman G., et al. A phase I safety and pharmacokinetic (PK) study of recombinant Apo2L/TRAIL, an apoptosis-inducing protein in patients with advanced cancer. J. Clin. Oncol. ASCO Ann. Meeting Proc. 24 (2006) 3013
    • (2006) J. Clin. Oncol. ASCO Ann. Meeting Proc. , vol.24 , pp. 3013
    • Herbst, R.S.1    Mendelson, D.S.2    Ebbinghaus, S.3    Gordon, M.S.4    O'Dwyer, P.5    Lieberman, G.6
  • 83
    • 34248187996 scopus 로고    scopus 로고
    • Phase 1 pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor/related apoptosis-inducing ligand receptor-1
    • Tolcher A.W., Mita M., Meropol N.J., von Mehren M., Patnaik A., Padavic K., et al. Phase 1 pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor/related apoptosis-inducing ligand receptor-1. J. Clin. Oncol. 25 (2007) 1390-1396
    • (2007) J. Clin. Oncol. , vol.25 , pp. 1390-1396
    • Tolcher, A.W.1    Mita, M.2    Meropol, N.J.3    von Mehren, M.4    Patnaik, A.5    Padavic, K.6
  • 84
    • 33646390886 scopus 로고    scopus 로고
    • Results of a phase 2 trial of HGS-ETR 1 (Agonistic Human Monoclonal Antibody to TRAIL Receptor 1) in subjects with relapsed/refractory non-Hodgkin's Lymphoma (NHL)
    • 146-7A
    • Younes A., Vose J., Zelenetz A.D., et al. Results of a phase 2 trial of HGS-ETR 1 (Agonistic Human Monoclonal Antibody to TRAIL Receptor 1) in subjects with relapsed/refractory non-Hodgkin's Lymphoma (NHL). Blood 106 (2005) 146-7A
    • (2005) Blood , vol.106
    • Younes, A.1    Vose, J.2    Zelenetz, A.D.3
  • 85
    • 35948952826 scopus 로고    scopus 로고
    • Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers
    • Plummer R., Attard G., Pacey S., Li L., Razak A., Perrett R., et al. Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers. Clin. Cancer Res. 13 (2007) 6187-6194
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6187-6194
    • Plummer, R.1    Attard, G.2    Pacey, S.3    Li, L.4    Razak, A.5    Perrett, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.