-
1
-
-
11144311321
-
Antiretroviral therapy in previously untreated adults infected with the human immunodeficiency virus type I: Established and potential determinants of virological outcome
-
Lowe SH, Prins JM, Lange JM. Antiretroviral therapy in previously untreated adults infected with the human immunodeficiency virus type I: established and potential determinants of virological outcome. Neth J Med. 2004;62:424-40.
-
(2004)
Neth J Med
, vol.62
, pp. 424-440
-
-
Lowe, S.H.1
Prins, J.M.2
Lange, J.M.3
-
2
-
-
0034456413
-
Determinants of virological response to antiretroviral therapy: Implications for long-term strategies
-
Deeks SG. Determinants of virological response to antiretroviral therapy: implications for long-term strategies. Clin Infect Dis. 2000;30 Suppl 2: S177-84.
-
(2000)
Clin Infect Dis
, vol.30
, Issue.SUPPL. 2
-
-
Deeks, S.G.1
-
3
-
-
0036257012
-
Adherence to antiretroviral therapy by human immunodeficiency virus-infected patients
-
Turner BJ. Adherence to antiretroviral therapy by human immunodeficiency virus-infected patients. J Infect Dis. 2002;185 Suppl 2: S143-51.
-
(2002)
J Infect Dis
, vol.185
, Issue.SUPPL. 2
-
-
Turner, B.J.1
-
4
-
-
0037114851
-
Virologic and immunologic response, clinical progression, and highly active antiretroviral therapy adherence
-
Press N, Tyndall MW, Wood E, Hogg RS, Montaner JS. Virologic and immunologic response, clinical progression, and highly active antiretroviral therapy adherence. J Acquir Immune Defic Syndr. 2002;31:S112-7.
-
(2002)
J Acquir Immune Defic Syndr
, vol.31
-
-
Press, N.1
Tyndall, M.W.2
Wood, E.3
Hogg, R.S.4
Montaner, J.S.5
-
5
-
-
3042716048
-
The pharmacogenetics of antiretroviral therapy: A review of studies to date
-
Quirk E, McLeod H, Powderly W. The pharmacogenetics of antiretroviral therapy: a review of studies to date. Clin Infect Dis. 2004;39:98-106.
-
(2004)
Clin Infect Dis
, vol.39
, pp. 98-106
-
-
Quirk, E.1
McLeod, H.2
Powderly, W.3
-
7
-
-
7544219932
-
Pharmacogenetics-based new therapeutic concepts
-
Roots I, Gerloff T, Meisel C, Kirchheiner J, Goldammer M, Kaiser R, et al. Pharmacogenetics-based new therapeutic concepts. Drug Metab Rev. 2004;36:617-38.
-
(2004)
Drug Metab Rev
, vol.36
, pp. 617-638
-
-
Roots, I.1
Gerloff, T.2
Meisel, C.3
Kirchheiner, J.4
Goldammer, M.5
Kaiser, R.6
-
8
-
-
4544291786
-
Pharmacogenomics: The influence of genomic variation on drug response
-
Thomas FJ, McLeod HL, Watters JW. Pharmacogenomics: the influence of genomic variation on drug response. Curr Top Med Chem. 2004;4:1399-409.
-
(2004)
Curr Top Med Chem
, vol.4
, pp. 1399-1409
-
-
Thomas, F.J.1
McLeod, H.L.2
Watters, J.W.3
-
9
-
-
4544292592
-
Pharmacogenetics or the promise of a personalized medicine: Variability in drug metabolism and transport
-
Allorge D, Loriot MA. Pharmacogenetics or the promise of a personalized medicine: variability in drug metabolism and transport. Ann Biol Clin (Paris). 2004;62:499-511.
-
(2004)
Ann Biol Clin (Paris)
, vol.62
, pp. 499-511
-
-
Allorge, D.1
Loriot, M.A.2
-
10
-
-
1642523162
-
Polymorphism inhuman MDR1 (P-glycoprotein): Recent advances and clinical relevance
-
Marzolini C, Paus E, Buclin T, Kim RB. Polymorphism inhuman MDR1 (P-glycoprotein): recent advances and clinical relevance. Clin Pharmacol Ther. 2004;75:13-33.
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 13-33
-
-
Marzolini, C.1
Paus, E.2
Buclin, T.3
Kim, R.B.4
-
11
-
-
0031158805
-
The physiological function of drug-transporting P-glycoproteins
-
Schinkel AH. The physiological function of drug-transporting P-glycoproteins. Semin Cancer Biol. 1997;8:161-70.
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 161-170
-
-
Schinkel, A.H.1
-
12
-
-
0007544439
-
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
-
Van Helvoort A, Smith AJ, Sprong H, Fritzsche I, Schinkel AH, Borst P, et al. MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell. 1996;87:507-17.
-
(1996)
Cell
, vol.87
, pp. 507-517
-
-
Van Helvoort, A.1
Smith, A.J.2
Sprong, H.3
Fritzsche, I.4
Schinkel, A.H.5
Borst, P.6
-
13
-
-
4243801613
-
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
-
Schinkel A, Mayer U, Wagenaar E, Mol C, Van Deemter L, Smit J, et al. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc Natl Acad Sci U S A. 1997;94:4028-33.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 4028-4033
-
-
Schinkel, A.1
Mayer, U.2
Wagenaar, E.3
Mol, C.4
Van Deemter, L.5
Smit, J.6
-
14
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, Von Richter O, Arnold HP, Brockmoller J, Johne A, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A. 2000;97:3473-8.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
-
15
-
-
0032518290
-
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
-
Kim RB, Fromm MF, Wandel C, Leake B, Wood AJ, Roden DM, et al. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J Clin Invest. 1998;101:289-94.
-
(1998)
J Clin Invest
, vol.101
, pp. 289-294
-
-
Kim, R.B.1
Fromm, M.F.2
Wandel, C.3
Leake, B.4
Wood, A.J.5
Roden, D.M.6
-
16
-
-
17144432270
-
Renal tubular transporters and antiviral drugs: An update
-
Izzedine H, Launay-Vacher V, Deray G. Renal tubular transporters and antiviral drugs: an update. AIDS. 2005;19:455-62.
-
(2005)
AIDS
, vol.19
, pp. 455-462
-
-
Izzedine, H.1
Launay-Vacher, V.2
Deray, G.3
-
17
-
-
0031921312
-
Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption
-
Smit JW, Schinkel AH, Muller M, Weert B, Meijer DK. Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption. Hepatology. 1998;27:1056-63.
-
(1998)
Hepatology
, vol.27
, pp. 1056-1063
-
-
Smit, J.W.1
Schinkel, A.H.2
Muller, M.3
Weert, B.4
Meijer, D.K.5
-
19
-
-
0033562673
-
HIV protease inhibitor ritonavir: A more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833
-
Drewe J, Gutmann H, Fricker G, Torok M, Berlinger C, Huwyler J. HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833. Biochem Pharmacol. 1999;57:1147-52.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 1147-1152
-
-
Drewe, J.1
Gutmann, H.2
Fricker, G.3
Torok, M.4
Berlinger, C.5
Huwyler, J.6
-
20
-
-
2542612168
-
Ritonavir decreases the nonrenal clearance of digoxin in healthy volunteers with known MDR1 genotypes
-
Penzak SR, Shen JM, Alfaro RM, Remaley AT, Natarajan V, Falloon J. Ritonavir decreases the nonrenal clearance of digoxin in healthy volunteers with known MDR1 genotypes. Ther Drug Monit. 2004;26:322-30.
-
(2004)
Ther Drug Monit
, vol.26
, pp. 322-330
-
-
Penzak, S.R.1
Shen, J.M.2
Alfaro, R.M.3
Remaley, A.T.4
Natarajan, V.5
Falloon, J.6
-
21
-
-
0035958776
-
P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: Potential for accelerated viral drug resistance?
-
Jones K, Bray PG, Khoo SH, Davey RA, Meaden ER, Ward SA, et al. P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance? AIDS. 2001;15:1353-8.
-
(2001)
AIDS
, vol.15
, pp. 1353-1358
-
-
Jones, K.1
Bray, P.G.2
Khoo, S.H.3
Davey, R.A.4
Meaden, E.R.5
Ward, S.A.6
-
22
-
-
0035853376
-
Differences in the intracellular accumulation of HIV protease inhibitors in vitro and the effect of active transport
-
Jones K, Hoggard PG, Sales SD, Khoo, Davey R, Back DJ. Differences in the intracellular accumulation of HIV protease inhibitors in vitro and the effect of active transport. AIDS. 2001;15:675-81.
-
(2001)
AIDS
, vol.15
, pp. 675-681
-
-
Jones, K.1
Hoggard, P.G.2
Sales, S.D.3
Khoo4
Davey, R.5
Back, D.J.6
-
23
-
-
0034121122
-
Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes
-
Choo EF, Leake B, Wandel C, Inamura H, Wood AJ, Wilkinson Gr, et al. Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes. Drug Metab Dispos. 2000;28:655-60.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 655-660
-
-
Choo, E.F.1
Leake, B.2
Wandel, C.3
Inamura, H.4
Wood, A.J.5
Wilkinson, G.6
-
24
-
-
0035063261
-
P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir
-
Huisman MT, Smit JW, Wiltshire HR, Hoetelmans RM, Bejinen JH, Schinkel AH. P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir. Mol Pharmacol. 2001;59:806-13.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 806-813
-
-
Huisman, M.T.1
Smit, J.W.2
Wiltshire, H.R.3
Hoetelmans, R.M.4
Bejinen, J.H.5
Schinkel, A.H.6
-
25
-
-
0033827147
-
The disposition of saquinavir in normal and P-glycoprotein deficient mice, rats, and in cultured cells
-
Washington CB, Wiltshire HR, Man M, Moy T, Harris SR, Worth E, et al. The disposition of saquinavir in normal and P-glycoprotein deficient mice, rats, and in cultured cells. Drug Metab Dispos. 2000;28:1058-62.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1058-1062
-
-
Washington, C.B.1
Wiltshire, H.R.2
Man, M.3
Moy, T.4
Harris, S.R.5
Worth, E.6
-
26
-
-
0032701128
-
Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure
-
Smit JW, Huisman MT, Van Tellingen O, Wiltshire HR, Schinkel AH. Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure. J Clin Invest. 1999;104:1441-7.
-
(1999)
J Clin Invest
, vol.104
, pp. 1441-1447
-
-
Smit, J.W.1
Huisman, M.T.2
Van Tellingen, O.3
Wiltshire, H.R.4
Schinkel, A.H.5
-
27
-
-
0033936554
-
Enhanced penetration of indinavir in cerebrospinal fluid and semen after the addition of low-dose ritonavir
-
Van Praag RM, Weverling GJ, Portegies P, Jurriaans S, Zhou XJ, Turner-Foisy ML, et al. Enhanced penetration of indinavir in cerebrospinal fluid and semen after the addition of low-dose ritonavir. AIDS. 2000;14:1187-94.
-
(2000)
AIDS
, vol.14
, pp. 1187-1194
-
-
Van Praag, R.M.1
Weverling, G.J.2
Portegies, P.3
Jurriaans, S.4
Zhou, X.J.5
Turner-Foisy, M.L.6
-
28
-
-
27744562662
-
MRP3, BCRP, and P-glycoprotein activities are prognostic factors in adult acute myeloid leukemia
-
Benderra Z, Faussat AM, Sayada L, Perrot JY, Tang R, Chaoui D, et al. MRP3, BCRP, and P-glycoprotein activities are prognostic factors in adult acute myeloid leukemia. Clin Cancer Res. 2005;11:7764-72.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7764-7772
-
-
Benderra, Z.1
Faussat, A.M.2
Sayada, L.3
Perrot, J.Y.4
Tang, R.5
Chaoui, D.6
-
29
-
-
0032953920
-
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
-
Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, Pierson T, et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med. 1999;5:512-7.
-
(1999)
Nat Med
, vol.5
, pp. 512-517
-
-
Finzi, D.1
Blankson, J.2
Siliciano, J.D.3
Margolick, J.B.4
Chadwick, K.5
Pierson, T.6
-
30
-
-
0033609374
-
Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy
-
Furtado MR, Callaway DS, Phair JP, Kunstman KJ, Stanton JL, Macken CA, et al. Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy. N Engl J Med. 1999;340:1614-22.
-
(1999)
N Engl J Med
, vol.340
, pp. 1614-1622
-
-
Furtado, M.R.1
Callaway, D.S.2
Phair, J.P.3
Kunstman, K.J.4
Stanton, J.L.5
Macken, C.A.6
-
31
-
-
0038468339
-
Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo
-
Hermankova M, Siliciano JD, Zhou Y, Monie D, Chadwick K, Margolick JB, et al. Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo. J Virol. 2003;77:7383-92.
-
(2003)
J Virol
, vol.77
, pp. 7383-7392
-
-
Hermankova, M.1
Siliciano, J.D.2
Zhou, Y.3
Monie, D.4
Chadwick, K.5
Margolick, J.B.6
-
32
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among Europeans Americans and African Americans
-
Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI, et al. Identification of functionally variant MDR1 alleles among Europeans Americans and African Americans. Clin Pharmacol Ther. 2001;70:189-99.
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
Dresser, G.K.4
Kubba, S.V.5
Schwarz, U.I.6
-
33
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multi-drug resistance (MDR)-1 gene
-
Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, et al. Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multi-drug resistance (MDR)-1 gene. J Pharmacol Exp Ther. 2001;297:1137-43.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
Inoue, K.4
Ito, S.5
Kanamori, Y.6
-
34
-
-
0036104334
-
Functional polymorphisms of the human multidrug resistance (MDR1) gene: Correlation with P-glycoprotein expresion and activity in vivo
-
Brinkmann U. Functional polymorphisms of the human multidrug resistance (MDR1) gene: correlation with P-glycoprotein expresion and activity in vivo. Novartis Found Symp. 2002;243:207-10.
-
(2002)
Novartis Found Symp
, vol.243
, pp. 207-210
-
-
Brinkmann, U.1
-
35
-
-
33646840851
-
Differences in CYP3A5*3 Genotype Distribution and Combinations With Other Polymorphisms Between Spaniards and Other Caucasian Populations
-
Gervasini G, Vizcaíno S, Gasiba C, Carrillo JA, Benítez J. Differences in CYP3A5*3 Genotype Distribution and Combinations With Other Polymorphisms Between Spaniards and Other Caucasian Populations. Ther Drug Monit. 2005;27:819-21.
-
(2005)
Ther Drug Monit
, vol.27
, pp. 819-821
-
-
Gervasini, G.1
Vizcaíno, S.2
Gasiba, C.3
Carrillo, J.A.4
Benítez, J.5
-
36
-
-
0037431040
-
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1
-
Siddiqui A, Kerb R, Weale ME, Brinkmann U, Smith A, Goldstein DB, et al. Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. N Engl J Med. 2003;348:1442-8.
-
(2003)
N Engl J Med
, vol.348
, pp. 1442-1448
-
-
Siddiqui, A.1
Kerb, R.2
Weale, M.E.3
Brinkmann, U.4
Smith, A.5
Goldstein, D.B.6
-
37
-
-
0036729669
-
The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients
-
Zheng H, Webber S, Zeevi A, Schetz E, Zhang J, Lamba J, et al. The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients. Hum Immunol. 2002;63:765-70.
-
(2002)
Hum Immunol
, vol.63
, pp. 765-770
-
-
Zheng, H.1
Webber, S.2
Zeevi, A.3
Schetz, E.4
Zhang, J.5
Lamba, J.6
-
38
-
-
0037022006
-
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study
-
Fellay J, Marzolini C, Meaden ER, Back DJ, Buclin T, Chave JP, et al. Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet. 2002;359:30-6.
-
(2002)
Lancet
, vol.359
, pp. 30-36
-
-
Fellay, J.1
Marzolini, C.2
Meaden, E.R.3
Back, D.J.4
Buclin, T.5
Chave, J.P.6
-
39
-
-
0037462209
-
Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response
-
Brumme ZL, Dong WW, Chan KJ, Hogg RS, Montaner JS, O'Shaughnessy MV, et al. Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response. AIDS. 2003;17:201-8.
-
(2003)
AIDS
, vol.17
, pp. 201-208
-
-
Brumme, Z.L.1
Dong, W.W.2
Chan, K.J.3
Hogg, R.S.4
Montaner, J.S.5
O'Shaughnessy, M.V.6
-
40
-
-
0033737468
-
Cellular factors involved in the induction of resistance of HIV to antiretroviral agents
-
Turriziani O, Antonelli G, Dianzani F. Cellular factors involved in the induction of resistance of HIV to antiretroviral agents. Int J Antimicrob Agents. 2000;16:353-6.
-
(2000)
Int J Antimicrob Agents
, vol.16
, pp. 353-356
-
-
Turriziani, O.1
Antonelli, G.2
Dianzani, F.3
-
41
-
-
0034057157
-
Effect of ABC transporters on HIV-1 infection: Inhibition of virus production by the MDR1 transporter
-
Lee CG, Ramachandra M, Jeang KT, Martin MA, Pastan I, Gottesman MM. Effect of ABC transporters on HIV-1 infection: inhibition of virus production by the MDR1 transporter. FASEB J. 2000;14:516-22.
-
(2000)
FASEB J
, vol.14
, pp. 516-522
-
-
Lee, C.G.1
Ramachandra, M.2
Jeang, K.T.3
Martin, M.A.4
Pastan, I.5
Gottesman, M.M.6
-
42
-
-
0036681943
-
Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection
-
Speck RR, Yu XF, Hildreth J, Flexner C. Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection. J Infect Dis. 2002;186:332-40.
-
(2002)
J Infect Dis
, vol.186
, pp. 332-340
-
-
Speck, R.R.1
Yu, X.F.2
Hildreth, J.3
Flexner, C.4
-
43
-
-
0034012626
-
P-glycoprotein-overexpressing multidrug-resistant cells are resistant to infection by enveloped viruses that enter via the plasma membrane
-
Raviv Y, Puri A, Blumenthal R. P-glycoprotein-overexpressing multidrug-resistant cells are resistant to infection by enveloped viruses that enter via the plasma membrane. FASEB J. 2000;14:511-5.
-
(2000)
FASEB J
, vol.14
, pp. 511-515
-
-
Raviv, Y.1
Puri, A.2
Blumenthal, R.3
-
44
-
-
1442325336
-
MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment
-
Bleiber G, May M, Suárez C, Martínez R, Marzolini C, Egger M, et al. MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment. J Infect Dis. 2004;189:583-6.
-
(2004)
J Infect Dis
, vol.189
, pp. 583-586
-
-
Bleiber, G.1
May, M.2
Suárez, C.3
Martínez, R.4
Marzolini, C.5
Egger, M.6
-
45
-
-
6344294111
-
Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4
-
Owen A, Chandler B, Bray PG, Ward SA, Hart CA, Back DJ, et al. Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4. J Virol. 2004;78:12022-9.
-
(2004)
J Virol
, vol.78
, pp. 12022-12029
-
-
Owen, A.1
Chandler, B.2
Bray, P.G.3
Ward, S.A.4
Hart, C.A.5
Back, D.J.6
-
46
-
-
0034527653
-
Changes in lipid and protein constituents of rafts and caveolae in multidrug resistant cancer cells and their functional consequences
-
Lavie Y, Liscovitch M. Changes in lipid and protein constituents of rafts and caveolae in multidrug resistant cancer cells and their functional consequences. Glycoconj J. 2000;17:253-9.
-
(2000)
Glycoconj J
, vol.17
, pp. 253-259
-
-
Lavie, Y.1
Liscovitch, M.2
-
47
-
-
0037159922
-
Allele frequency of three functionally active polymorphisms of the MDR-1 gene in high-risk HIV-negative and HIV-positive Caucasians
-
Ifergan I, Bernard NF, Bruneau J, Alary M, Tsoukas CM, Roger M. Allele frequency of three functionally active polymorphisms of the MDR-1 gene in high-risk HIV-negative and HIV-positive Caucasians. AIDS. 2002;16:2340-2.
-
(2002)
AIDS
, vol.16
, pp. 2340-2342
-
-
Ifergan, I.1
Bernard, N.F.2
Bruneau, J.3
Alary, M.4
Tsoukas, C.M.5
Roger, M.6
-
48
-
-
0025145490
-
Human immunodeficiency virus I - induced expression of P-glycoprotein
-
Gollapudi S, Gupta S. Human immunodeficiency virus I - induced expression of P-glycoprotein. Biochem Biophys Res Común. 1990;171:1002-7.
-
(1990)
Biochem Biophys Res Común
, vol.171
, pp. 1002-1007
-
-
Gollapudi, S.1
Gupta, S.2
-
49
-
-
20144379266
-
HIV-Tat protein induces P-glycoprotein expression in brain microvascular endothelial cells
-
Hayashi K, Pu H, Tian J, Andras IE, Lee YW, Hennig B, et al. HIV-Tat protein induces P-glycoprotein expression in brain microvascular endothelial cells. J Neurochem. 2005;93:1231-41.
-
(2005)
J Neurochem
, vol.93
, pp. 1231-1241
-
-
Hayashi, K.1
Pu, H.2
Tian, J.3
Andras, I.E.4
Lee, Y.W.5
Hennig, B.6
-
50
-
-
0344059112
-
The expression of P-glycoprotein and cellular kinases is modulated at the transcriptional level by infection and highly active antiretroviral therapy in a primate model of AIDS
-
Jorajuria S, Clayette P, Dereuddre-Bosquet N, Benlhassan-Chahour K, Thiebot H, Vaslin B, et al. The expression of P-glycoprotein and cellular kinases is modulated at the transcriptional level by infection and highly active antiretroviral therapy in a primate model of AIDS. AIDS Res Hum Retroviruses. 2003;19:307-11.
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, pp. 307-311
-
-
Jorajuria, S.1
Clayette, P.2
Dereuddre-Bosquet, N.3
Benlhassan-Chahour, K.4
Thiebot, H.5
Vaslin, B.6
-
51
-
-
0029846735
-
Abnormal expression of a 170-kilodalton P-glycoprotein encoded by MDR1 gene, a metabolically active efflux pump, in CD4+ and CD8+ T cells from patients with human immunodeficiency virus type 1 infection
-
Andreana A, Aggarwal S, Gollapudi S, Wien D, Tsuruo T, Gupta S. Abnormal expression of a 170-kilodalton P-glycoprotein encoded by MDR1 gene, a metabolically active efflux pump, in CD4+ and CD8+ T cells from patients with human immunodeficiency virus type 1 infection. AIDS Res Hum Retroviruses. 1996;12:1457-62.
-
(1996)
AIDS Res Hum Retroviruses
, vol.12
, pp. 1457-1462
-
-
Andreana, A.1
Aggarwal, S.2
Gollapudi, S.3
Wien, D.4
Tsuruo, T.5
Gupta, S.6
-
52
-
-
0028978727
-
Transmembrane P-glycoprotein (PGP/P-170) in HIV infection: Analysis of lymphocyte surface expression and drug-unrelated function
-
Lucia MB, Cauda R, Landay AL, Malorni W, Donelli G, Ortona L. Transmembrane P-glycoprotein (PGP/P-170) in HIV infection: analysis of lymphocyte surface expression and drug-unrelated function. AIDS Res Hum Retroviruses. 1995;11:893-901.
-
(1995)
AIDS Res Hum Retroviruses
, vol.11
, pp. 893-901
-
-
Lucia, M.B.1
Cauda, R.2
Landay, A.L.3
Malorni, W.4
Donelli, G.5
Ortona, L.6
-
53
-
-
0034764807
-
Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients
-
Meaden ER, Hoggard PG, Maher B, Khoo SH, Back DJ. Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients. AIDS Res Hum Retroviruses. 2001;17:1329-32.
-
(2001)
AIDS Res Hum Retroviruses
, vol.17
, pp. 1329-1332
-
-
Meaden, E.R.1
Hoggard, P.G.2
Maher, B.3
Khoo, S.H.4
Back, D.J.5
-
54
-
-
0031882085
-
Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell subsets from healthy donors and HIV-infected patients
-
Malorni W, Lucia MB, Rainaldi G, Cauda R, Cianfriglia M, Donelli G, et al. Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell subsets from healthy donors and HIV-infected patients. Haematologica. 1998;83:13-20.
-
(1998)
Haematologica
, vol.83
, pp. 13-20
-
-
Malorni, W.1
Lucia, M.B.2
Rainaldi, G.3
Cauda, R.4
Cianfriglia, M.5
Donelli, G.6
-
55
-
-
18544403962
-
Detection of P-glycoprotein efflux activity on peripheral blood lymphocyte subsets from HIV + patients
-
Lucia MB, Rutella S, Rumi C, Ventura G, Caldarola G, Cauda R. Detection of P-glycoprotein efflux activity on peripheral blood lymphocyte subsets from HIV + patients. Eur J Histochem. 1997;41 Suppl 2:195-6.
-
(1997)
Eur J Histochem
, vol.41
, Issue.SUPPL. 2
, pp. 195-196
-
-
Lucia, M.B.1
Rutella, S.2
Rumi, C.3
Ventura, G.4
Caldarola, G.5
Cauda, R.6
-
56
-
-
0031293052
-
Surface P-glycoprotein expression on peripheral lymphocyte subpopulations from HIV-infected patients
-
Lucia MB, Rutella S, Rumi C, Cauda R. Surface P-glycoprotein expression on peripheral lymphocyte subpopulations from HIV-infected patients. Eur J Histochem. 1997;41 Suppl 2:33-4.
-
(1997)
Eur J Histochem
, vol.41
, Issue.SUPPL. 2
, pp. 33-34
-
-
Lucia, M.B.1
Rutella, S.2
Rumi, C.3
Cauda, R.4
-
57
-
-
0037264739
-
P-glycoprotein in blood CD4 cells of HIV-1-infected patients treated with protease inhibitors
-
Bossi P, Legrand O, Faussat AM, Legrand M, Bricaire F, Marie JP, et al. P-glycoprotein in blood CD4 cells of HIV-1-infected patients treated with protease inhibitors. HIV Med. 2003;4:67-71.
-
(2003)
HIV Med
, vol.4
, pp. 67-71
-
-
Bossi, P.1
Legrand, O.2
Faussat, A.M.3
Legrand, M.4
Bricaire, F.5
Marie, J.P.6
-
58
-
-
0036683035
-
In vitro and in vivo modulation of MDR1/P-glycoprotein in HIV-infected patients administered highly active antiretroviral therapy and liposomal doxorubicin
-
Lucia MB, Rutella S, Leone G, Larocca LM, Vella S, Cauda R. In vitro and in vivo modulation of MDR1/P-glycoprotein in HIV-infected patients administered highly active antiretroviral therapy and liposomal doxorubicin. J Acquir Immune Defic Syndr. 2002;30:369-78.
-
(2002)
J Acquir Immune Defic Syndr
, vol.30
, pp. 369-378
-
-
Lucia, M.B.1
Rutella, S.2
Leone, G.3
Larocca, L.M.4
Vella, S.5
Cauda, R.6
-
59
-
-
0035997339
-
Differential modulation of P-glycoprotein expression and activity by nonnucleoside HIV-1 reverse transcriptase inhibitors in cell culture
-
Stormer E, Von Moltke LL, Perloff MD, Greenblatt DJ. Differential modulation of P-glycoprotein expression and activity by nonnucleoside HIV-1 reverse transcriptase inhibitors in cell culture. Pharm Res. 2002;19:1038-45.
-
(2002)
Pharm Res
, vol.19
, pp. 1038-1045
-
-
Stormer, E.1
Von Moltke, L.L.2
Perloff, M.D.3
Greenblatt, D.J.4
-
60
-
-
23044446936
-
Pharmacogenetics of nevirapine and hepatoxicity: NWCS220, an ACTG collaborative study
-
Feb 22-25; Boston, Massachusetts. Abstract 833
-
Haas DW, Bartlett J, Anderson J, Sanne I, Wilkinson GR, Quinn J, et al. Pharmacogenetics of nevirapine and hepatoxicity: NWCS220, an ACTG collaborative study. In: Proceedings of the Twelfth Conference on Retroviruses and Opportunistic Infections; 2005 Feb 22-25; Boston, Massachusetts. Abstract 833.
-
(2005)
Proceedings of the Twelfth Conference on Retroviruses and Opportunistic Infections
-
-
Haas, D.W.1
Bartlett, J.2
Anderson, J.3
Sanne, I.4
Wilkinson, G.R.5
Quinn, J.6
-
61
-
-
0042627777
-
The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro
-
Chandler B, Almond L, Ford J, Owen A, Hoggard P, Khoo S, et al. The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro. J Acquir Immune Defic Syndr. 2003;15;33:551-6.
-
(2003)
J Acquir Immune Defic Syndr
, vol.15
, Issue.33
, pp. 551-556
-
-
Chandler, B.1
Almond, L.2
Ford, J.3
Owen, A.4
Hoggard, P.5
Khoo, S.6
-
62
-
-
0032765899
-
Interactions of HIV protease inhibitors with ATP-dependent drug export proteins
-
Gutman H, Fricker G, Drewe J, Toeroek M, Miller DS. Interactions of HIV protease inhibitors with ATP-dependent drug export proteins. Mol Pharmacol. 1999;56:383-9.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 383-389
-
-
Gutman, H.1
Fricker, G.2
Drewe, J.3
Toeroek, M.4
Miller, D.S.5
-
63
-
-
0032211902
-
Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (PGP) in human cultured cells
-
Washington CB, Duran GE, Man MC, Sikic BI, Blaschke TF. Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (PGP) in human cultured cells. J Acquir Immune Defic Syndr. 1998;19:203-9.
-
(1998)
J Acquir Immune Defic Syndr
, vol.19
, pp. 203-209
-
-
Washington, C.B.1
Duran, G.E.2
Man, M.C.3
Sikic, B.I.4
Blaschke, T.F.5
-
64
-
-
0033946706
-
Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture
-
Perloff MD, Von Moltke LL, Fahey JM, Daily JP, Greenblatt DJ. Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture. AIDS. 2000;14:1287-9.
-
(2000)
AIDS
, vol.14
, pp. 1287-1289
-
-
Perloff, M.D.1
Von Moltke, L.L.2
Fahey, J.M.3
Daily, J.P.4
Greenblatt, D.J.5
-
65
-
-
0035424103
-
HIV-protease inhibitors contribute to P-glycoprotein efflux function defect in peripheral blood lymphocytes from HIV-positive patients receiving HAART
-
Lucia MB, Rutella S, Leone G, Vella S, Cauda R. HIV-protease inhibitors contribute to P-glycoprotein efflux function defect in peripheral blood lymphocytes from HIV-positive patients receiving HAART. J Acquir Immune Defic Syndr. 2001;27:321-30.
-
(2001)
J Acquir Immune Defic Syndr
, vol.27
, pp. 321-330
-
-
Lucia, M.B.1
Rutella, S.2
Leone, G.3
Vella, S.4
Cauda, R.5
-
66
-
-
0037258996
-
Effects of nelfinavir and its M8 metabolite on lymphocyte P-glycoprotein activity during antiretroviral therapy
-
Donahue JP, Dowdy D, Ratnam KK, Hulgan T, Price J, Unutmaz D, et al. Effects of nelfinavir and its M8 metabolite on lymphocyte P-glycoprotein activity during antiretroviral therapy. Clin Pharmacol Ther. 2003;73:78-86.
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 78-86
-
-
Donahue, J.P.1
Dowdy, D.2
Ratnam, K.K.3
Hulgan, T.4
Price, J.5
Unutmaz, D.6
-
67
-
-
0033371825
-
Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors
-
Profit L, Eagling VA, Back DJ. Modulation of P-glycoprotein function in human lymphocytes and Caco-2 cell monolayers by HIV-1 protease inhibitors. AIDS. 1999;13:1623-7.
-
(1999)
AIDS
, vol.13
, pp. 1623-1627
-
-
Profit, L.1
Eagling, V.A.2
Back, D.J.3
-
68
-
-
0034528918
-
Inhibitory effect of human immunodeficiency virus protease inhibitors on multidrug resistance transporter P-glycoproteins
-
Shiraki N, Hamada A, Yasuda K, Fujii J, Arimori K, Nakano M. Inhibitory effect of human immunodeficiency virus protease inhibitors on multidrug resistance transporter P-glycoproteins. Biol Pharm Bull. 2000;23:1528-31.
-
(2000)
Biol Pharm Bull
, vol.23
, pp. 1528-1531
-
-
Shiraki, N.1
Hamada, A.2
Yasuda, K.3
Fujii, J.4
Arimori, K.5
Nakano, M.6
-
69
-
-
23244461676
-
Atazanavir inhibits P-glycoprotein and multidrug resistance-associated protein efflux activity
-
Lucia MB, Golotta C, Rutella S, Rastrelli E, Savarino A, Cauda R. Atazanavir inhibits P-glycoprotein and multidrug resistance-associated protein efflux activity. J Acquir Immune Defic Syndr. 2005;39:635-7.
-
(2005)
J Acquir Immune Defic Syndr
, vol.39
, pp. 635-637
-
-
Lucia, M.B.1
Golotta, C.2
Rutella, S.3
Rastrelli, E.4
Savarino, A.5
Cauda, R.6
-
70
-
-
18844409566
-
Atazanavir: Effects on P-glycoprotein transport and CYP3A metabolism in vitro
-
Perloff ES, Duan SX, Skolnik PR, Greenblatt DJ, Von Moltke LL. Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro. Drug Metab Dispos. 2005;33:764-70.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 764-770
-
-
Perloff, E.S.1
Duan, S.X.2
Skolnik, P.R.3
Greenblatt, D.J.4
Von Moltke, L.L.5
-
71
-
-
15944414161
-
An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children
-
Saitoh A, Singh KK, Powell CA, Fenton T, Fletcher CV, Brundage R, et al. An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children. AIDS. 2005;19:371-80.
-
(2005)
AIDS
, vol.19
, pp. 371-380
-
-
Saitoh, A.1
Singh, K.K.2
Powell, C.A.3
Fenton, T.4
Fletcher, C.V.5
Brundage, R.6
-
72
-
-
27244452745
-
Effect of efavirenz on intestinal p-glycoprotein and hepatic p450 function in rats
-
Berruet N, Sentenac S, Auchere D, Giménez F, Farinotti R, Fernández C. Effect of efavirenz on intestinal p-glycoprotein and hepatic p450 function in rats. J Pharm Pharm Sci. 2005;8:226-34.
-
(2005)
J Pharm Pharm Sci
, vol.8
, pp. 226-234
-
-
Berruet, N.1
Sentenac, S.2
Auchere, D.3
Giménez, F.4
Farinotti, R.5
Fernández, C.6
-
73
-
-
0141958217
-
Implications of T-cell P-glycoprotein activity during HIV-1 infection and its therapy
-
Hulgan T, Donahue JP, Hawkins C, Unutmaz D, D'Aquila RT, Raffanti S, et al. Implications of T-cell P-glycoprotein activity during HIV-1 infection and its therapy. J Acquir Immune Defic Syndr. 2003;34:119-26.
-
(2003)
J Acquir Immune Defic Syndr
, vol.34
, pp. 119-126
-
-
Hulgan, T.1
Donahue, J.P.2
Hawkins, C.3
Unutmaz, D.4
D'Aquila, R.T.5
Raffanti, S.6
-
74
-
-
85031382902
-
-
Owen A, Almond L, Hartkoorn R, Walsh T, Youle M, Bonington A, et al. Relevance of drug transporters and drug metabolism enzymes to nevirapine disposition: superimposition of host genotypes. In: Program and abstracts of the 12th Conference on Retroviruses and Opportunistic Infections; February 22-25, 2005; Boston, Massachusetts. Abstract 650.
-
Owen A, Almond L, Hartkoorn R, Walsh T, Youle M, Bonington A, et al. Relevance of drug transporters and drug metabolism enzymes to nevirapine disposition: superimposition of host genotypes. In: Program and abstracts of the 12th Conference on Retroviruses and Opportunistic Infections; February 22-25, 2005; Boston, Massachusetts. Abstract 650.
-
-
-
-
75
-
-
3142751539
-
No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment
-
Winzer R, Langmann P, Zilly M, Tollmann F, Schubert J, Klinker H, et al. No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment. Eur J Med Res. 2003;8:531-4.
-
(2003)
Eur J Med Res
, vol.8
, pp. 531-534
-
-
Winzer, R.1
Langmann, P.2
Zilly, M.3
Tollmann, F.4
Schubert, J.5
Klinker, H.6
-
76
-
-
27944466136
-
Absence of association between MDR1 genetic polymorphisms, indinavir pharmacokinetics and response to highly active antiretroviral therapy
-
Verstuyft C, Marcellin F, Morand-Joubert L, Launay O, Brendel K, Mentre F, et al. Absence of association between MDR1 genetic polymorphisms, indinavir pharmacokinetics and response to highly active antiretroviral therapy. AIDS. 2005;19:2127-31.
-
(2005)
AIDS
, vol.19
, pp. 2127-2131
-
-
Verstuyft, C.1
Marcellin, F.2
Morand-Joubert, L.3
Launay, O.4
Brendel, K.5
Mentre, F.6
-
77
-
-
27944460707
-
Pharmacogenetics of Long-Term Responses to Antiretroviral Regimens Containing Efavirenz and/or Nelfinavir: An Adult AIDS Clinical Trials Group Study
-
Haas DW, Smeaton LM, Shafer RW, Robbins GK, Morse GD, Labbe L, et al. Pharmacogenetics of Long-Term Responses to Antiretroviral Regimens Containing Efavirenz and/or Nelfinavir: An Adult AIDS Clinical Trials Group Study. J Infect Dis. 2005;192:1931-42.
-
(2005)
J Infect Dis
, vol.192
, pp. 1931-1942
-
-
Haas, D.W.1
Smeaton, L.M.2
Shafer, R.W.3
Robbins, G.K.4
Morse, G.D.5
Labbe, L.6
-
78
-
-
0026489591
-
Resistance of HIV-1 to AZT might also involve the cellular expression of multidrug resistance P-glycoprotein
-
Antonelli G, Turriziani O, Cianfriglia M, Riva E, Dong G, Fattorossi A, et al. Resistance of HIV-1 to AZT might also involve the cellular expression of multidrug resistance P-glycoprotein. AIDS Res Hum Retroviruses. 1992;8:1839-44.
-
(1992)
AIDS Res Hum Retroviruses
, vol.8
, pp. 1839-1844
-
-
Antonelli, G.1
Turriziani, O.2
Cianfriglia, M.3
Riva, E.4
Dong, G.5
Fattorossi, A.6
-
79
-
-
0036155184
-
Intracellular pharmacology of nucleoside analogues and protease inhibitors: Role of transporter molecules
-
Hoggard PG, Back DJ. Intracellular pharmacology of nucleoside analogues and protease inhibitors: role of transporter molecules. Curr Opin Infect Dis. 2002;15:3-8.
-
(2002)
Curr Opin Infect Dis
, vol.15
, pp. 3-8
-
-
Hoggard, P.G.1
Back, D.J.2
-
80
-
-
27944460405
-
Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, PGP and BCRP
-
Janneh O, Owen A, Chandler B, Hartkoorn RC, Hart CA, Bray PG, et al. Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, PGP and BCRP. AIDS. 2005;19:2097-102.
-
(2005)
AIDS
, vol.19
, pp. 2097-2102
-
-
Janneh, O.1
Owen, A.2
Chandler, B.3
Hartkoorn, R.C.4
Hart, C.A.5
Bray, P.G.6
-
81
-
-
0036864550
-
Intracellular concentration of protease inhibitors in HIV-1-infected patients: Correlation with MDR-1 gene expression and low dose of ritonavir
-
Chaillou S, Durant J, Garraffo R, Georgenthum E, Roptin C, Dunais B, et al. Intracellular concentration of protease inhibitors in HIV-1-infected patients: correlation with MDR-1 gene expression and low dose of ritonavir. HIV Clin Trials. 2002;3:493-501.
-
(2002)
HIV Clin Trials
, vol.3
, pp. 493-501
-
-
Chaillou, S.1
Durant, J.2
Garraffo, R.3
Georgenthum, E.4
Roptin, C.5
Dunais, B.6
-
82
-
-
1542288853
-
Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients
-
Hennessy M, Clarke S, Spiers JP, Kelleher D, Mulcahy F, Hoggard P, et al. Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients. Antivir Ther. 2004;9:115-22.
-
(2004)
Antivir Ther
, vol.9
, pp. 115-122
-
-
Hennessy, M.1
Clarke, S.2
Spiers, J.P.3
Kelleher, D.4
Mulcahy, F.5
Hoggard, P.6
-
83
-
-
3042631503
-
Intracellular and plasma pharmacokinetics of saquinavir-ritonavir, administered at 1,600/100 milligrams once daily in human immunodeficiency virus-infected patients
-
Ford J, Boffito M, Wildfire A, Hill A, Back D, Khoo S, et al. Intracellular and plasma pharmacokinetics of saquinavir-ritonavir, administered at 1,600/100 milligrams once daily in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother. 2004;48:2388-93.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2388-2393
-
-
Ford, J.1
Boffito, M.2
Wildfire, A.3
Hill, A.4
Back, D.5
Khoo, S.6
-
84
-
-
27144505125
-
Intracellular and plasma pharmacokinetics of efavirenz in HIV-infected individuals
-
Almond LM, Hoggard PG, Edirisinghe D, Khoo SH, Back DJ. Intracellular and plasma pharmacokinetics of efavirenz in HIV-infected individuals. J Antimicrob Chemother. 2005;56:738-44.
-
(2005)
J Antimicrob Chemother
, vol.56
, pp. 738-744
-
-
Almond, L.M.1
Hoggard, P.G.2
Edirisinghe, D.3
Khoo, S.H.4
Back, D.J.5
-
85
-
-
23444450261
-
Intracellular and plasma pharmacokinetics of nevirapine in human immunodeficiency virus-infected individuals
-
Almond LM, Edirisinghe D, Dalton M, Bonington A, Back DJ, Khoo SH. Intracellular and plasma pharmacokinetics of nevirapine in human immunodeficiency virus-infected individuals. Clin Pharmacol Ther. 2005;78:132-42.
-
(2005)
Clin Pharmacol Ther
, vol.78
, pp. 132-142
-
-
Almond, L.M.1
Edirisinghe, D.2
Dalton, M.3
Bonington, A.4
Back, D.J.5
Khoo, S.H.6
-
86
-
-
0242664934
-
MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: An adult AIDS Clinical Trials Group study
-
Haas DW, Wu H, Li H, Bosch RJ, Lederman MM, Kuritzkes D, et al. MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study. J Acquir Immune Defic Syndr. 2003;34:295-8.
-
(2003)
J Acquir Immune Defic Syndr
, vol.34
, pp. 295-298
-
-
Haas, D.W.1
Wu, H.2
Li, H.3
Bosch, R.J.4
Lederman, M.M.5
Kuritzkes, D.6
-
87
-
-
0042127239
-
MDR1 C3435T genetic polymorphism does not influence the response to antiretroviral therapy in drug-naive HIV-positive patients
-
Nasi M, Borghi V, Pinti M, Bellodi C, Lugli E, Maffei S, et al. MDR1 C3435T genetic polymorphism does not influence the response to antiretroviral therapy in drug-naive HIV-positive patients. AIDS. 2003;17:1696-8.
-
(2003)
AIDS
, vol.17
, pp. 1696-1698
-
-
Nasi, M.1
Borghi, V.2
Pinti, M.3
Bellodi, C.4
Lugli, E.5
Maffei, S.6
-
88
-
-
0035808574
-
Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients
-
Marzolini C, Telenti A, Decosterd LA, Greub G, Biollaz J, Buclin T. Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients. AIDS. 2001;15:71-5.
-
(2001)
AIDS
, vol.15
, pp. 71-75
-
-
Marzolini, C.1
Telenti, A.2
Decosterd, L.A.3
Greub, G.4
Biollaz, J.5
Buclin, T.6
-
89
-
-
28044459173
-
Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring
-
Gutiérrez F, Navarro A, Padilla S, Antón R, Masía M, Borrás J, et al. Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring. Clin Infect Dis. 2005;41:1648-53.
-
(2005)
Clin Infect Dis
, vol.41
, pp. 1648-1653
-
-
Gutiérrez, F.1
Navarro, A.2
Padilla, S.3
Antón, R.4
Masía, M.5
Borrás, J.6
-
90
-
-
19944428456
-
Pharmacogenetics of efavirenz and central nervous system side effects: An Adult AIDS Clinical Trials Group study
-
Haas DW, RiBbaudo HJ, Kim RB, Tierney C, Wilkinson GR, Gulick RM, et al. Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study. AIDS. 2004;18:2391-400.
-
(2004)
AIDS
, vol.18
, pp. 2391-2400
-
-
Haas, D.W.1
RiBbaudo, H.J.2
Kim, R.B.3
Tierney, C.4
Wilkinson, G.R.5
Gulick, R.M.6
-
91
-
-
85031373279
-
-
Ritchie M, Haas D, Motsinger A, Donahue J, Erdem H, Raffanti S, et al. Genetic variation in drug transporter and metabolizing enzyme genes may be associated with non-nucleoside reverse transcriptase inhibitor hepatotoxicity. In: Program and abstracts of the 12th Conference on Retroviruses and Opportunistic Infections; February 22-25, 2005; Boston, Massachussets. Abstract 832.
-
Ritchie M, Haas D, Motsinger A, Donahue J, Erdem H, Raffanti S, et al. Genetic variation in drug transporter and metabolizing enzyme genes may be associated with non-nucleoside reverse transcriptase inhibitor hepatotoxicity. In: Program and abstracts of the 12th Conference on Retroviruses and Opportunistic Infections; February 22-25, 2005; Boston, Massachussets. Abstract 832.
-
-
-
-
93
-
-
0031686969
-
Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP
-
Rowinsky EK, Smith L, Wang YM, Chaturvedi P, Villalona M, Campbell E, et al. Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP. J Clin Oncol. 1998;16:2964-76.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2964-2976
-
-
Rowinsky, E.K.1
Smith, L.2
Wang, Y.M.3
Chaturvedi, P.4
Villalona, M.5
Campbell, E.6
-
94
-
-
3242688711
-
A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma
-
Bates SE, Bakke S, Kang M, Robey RW, Zhai S, Thambi P, et al. A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma. Clin Cancer Res. 2004;10:4724-33.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4724-4733
-
-
Bates, S.E.1
Bakke, S.2
Kang, M.3
Robey, R.W.4
Zhai, S.5
Thambi, P.6
-
95
-
-
23044500423
-
Phase I study of pegylated liposomal doxorubicin and the multidrug-resistance modulator, valspodar
-
Fracasso PM, Blum KA, Ma MK, Tan BR, Wright LP, Goodner SA, et al. Phase I study of pegylated liposomal doxorubicin and the multidrug-resistance modulator, valspodar. Br J Cancer. 2005;93:46-53.
-
(2005)
Br J Cancer
, vol.93
, pp. 46-53
-
-
Fracasso, P.M.1
Blum, K.A.2
Ma, M.K.3
Tan, B.R.4
Wright, L.P.5
Goodner, S.A.6
-
96
-
-
33645097407
-
Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in rats
-
Anderson BD, May MJ, Jordan S, Song L, Roberts MJ, Leggas M. Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in rats. Drug Metab Dispos. 2006;34:653-9.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 653-659
-
-
Anderson, B.D.1
May, M.J.2
Jordan, S.3
Song, L.4
Roberts, M.J.5
Leggas, M.6
-
97
-
-
2542479863
-
A Phase I trial of a potent P-glycoprotein inhibitor, zosuquidar trihydrochloride (LY335979), administered intravenously in combination with doxorubicin in patients with advanced malignancy
-
Sandler A, Gordon M, De Alwis DP, Pouliquen I, Green L, Marder P, et al. A Phase I trial of a potent P-glycoprotein inhibitor, zosuquidar trihydrochloride (LY335979), administered intravenously in combination with doxorubicin in patients with advanced malignancy. Clin Cancer Res. 2004;10:3265-72.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3265-3272
-
-
Sandler, A.1
Gordon, M.2
De Alwis, D.P.3
Pouliquen, I.4
Green, L.5
Marder, P.6
-
98
-
-
22144457872
-
A phase I pharmacokinetic study of the P-glycoprotein inhibitor, ONT-093, in combination with paclitaxel in patients with advanced cancer
-
Chi KN, Chia SK, Dixon R, Newman MJ, Wacher VJ, Sikic B, et al. A phase I pharmacokinetic study of the P-glycoprotein inhibitor, ONT-093, in combination with paclitaxel in patients with advanced cancer. Invest New Drugs. 2005;23:311-5.
-
(2005)
Invest New Drugs
, vol.23
, pp. 311-315
-
-
Chi, K.N.1
Chia, S.K.2
Dixon, R.3
Newman, M.J.4
Wacher, V.J.5
Sikic, B.6
-
99
-
-
11244321887
-
Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093)
-
Kuppens IE, Bosch TM, Van Maanen MJ, Rosing H, Fitzpatrick A, Beijnen JH, et al. Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093). Cancer Chemother Pharmacol. 2005;55:72-8.
-
(2005)
Cancer Chemother Pharmacol
, vol.55
, pp. 72-78
-
-
Kuppens, I.E.1
Bosch, T.M.2
Van Maanen, M.J.3
Rosing, H.4
Fitzpatrick, A.5
Beijnen, J.H.6
-
101
-
-
0042872962
-
Effect of MDR1 phosphorothioate antisense oligodeoxynucleotides in multidrug-resistant human tumor cell lines and xenografts
-
Ramachandran C, Wellham LL. Effect of MDR1 phosphorothioate antisense oligodeoxynucleotides in multidrug-resistant human tumor cell lines and xenografts. Anticancer Res. 2003;23:2681-90.
-
(2003)
Anticancer Res
, vol.23
, pp. 2681-2690
-
-
Ramachandran, C.1
Wellham, L.L.2
-
102
-
-
4043059428
-
Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides
-
Kang H, Fisher MH, Xu D, Miyamoto YJ, Marchand A, Van Aerschot A, et al. Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides. Nucleic Acids Res. 2004;32:4411-9.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 4411-4419
-
-
Kang, H.1
Fisher, M.H.2
Xu, D.3
Miyamoto, Y.J.4
Marchand, A.5
Van Aerschot, A.6
-
104
-
-
0036721426
-
Selective inhibition of P-glycoprotein expression in multidrug-resistant tumor cells by a designed transcriptional regulator
-
Xu D, Ye D, Fisher M, Juliano RL. Selective inhibition of P-glycoprotein expression in multidrug-resistant tumor cells by a designed transcriptional regulator. J Pharmacol Exp Ther. 2002;302:963-71.
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 963-971
-
-
Xu, D.1
Ye, D.2
Fisher, M.3
Juliano, R.L.4
-
105
-
-
0032055522
-
Restoration of retinoid sensitivity by MDR1 ribozymes in retinoic acid-resistant myeloid leukemic cells
-
Matsushita H, Kizaki M, Kobayashi H, Ueno H, Muto A, Takayama N, et al. Restoration of retinoid sensitivity by MDR1 ribozymes in retinoic acid-resistant myeloid leukemic cells. Blood. 1998;91:2452-8.
-
(1998)
Blood
, vol.91
, pp. 2452-2458
-
-
Matsushita, H.1
Kizaki, M.2
Kobayashi, H.3
Ueno, H.4
Muto, A.5
Takayama, N.6
-
106
-
-
0028231401
-
Reversal of drug sensitivity in multidrug-resistant tumor cells by an MDR1 (PGY1) ribozyme
-
Kobayashi H, Dorai T, Holland JF, Ohnuma T. Reversal of drug sensitivity in multidrug-resistant tumor cells by an MDR1 (PGY1) ribozyme. Cancer Res. 1994;54:1271-5.
-
(1994)
Cancer Res
, vol.54
, pp. 1271-1275
-
-
Kobayashi, H.1
Dorai, T.2
Holland, J.F.3
Ohnuma, T.4
-
107
-
-
0033135323
-
Retrovirus-mediated transfer of anti-MDR1 ribozymes fully restores chemosensitivity of P-glycoprotein-expressing human lymphoma cells
-
Wang FS, Kobayashi H, Liang KW, Holland JF, Ohnuma T. Retrovirus-mediated transfer of anti-MDR1 ribozymes fully restores chemosensitivity of P-glycoprotein-expressing human lymphoma cells. Hum Gene Ther. 1999;10:1185-95.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 1185-1195
-
-
Wang, F.S.1
Kobayashi, H.2
Liang, K.W.3
Holland, J.F.4
Ohnuma, T.5
|