-
1
-
-
0344825356
-
P-glycoprotein: From genomics to mechanism
-
Ambudkar,S.V., Kimchi-Sarfaty,C., Sauna,Z.E. and Gottesman,M.M. (2003) P-glycoprotein: from genomics to mechanism. Oncogene, 22, 7468-7485.
-
(2003)
Oncogene
, vol.22
, pp. 7468-7485
-
-
Ambudkar, S.V.1
Kimchi-Sarfaty, C.2
Sauna, Z.E.3
Gottesman, M.M.4
-
2
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
Juliano,R.L. and Ling,V. (1976) A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta, 455, 152-162.
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
3
-
-
0028149617
-
P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells
-
Licht,T., Pastan,I., Gottesman,M. and Herrmann,F. (1994) P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells. Ann. Hematol., 69, 159-171.
-
(1994)
Ann. Hematol.
, vol.69
, pp. 159-171
-
-
Licht, T.1
Pastan, I.2
Gottesman, M.3
Herrmann, F.4
-
4
-
-
0028307740
-
P-glycoprotein, multidrug-resistance and tumor progression
-
Bradley,G. and Ling,V. (1994) P-glycoprotein, multidrug-resistance and tumor progression. Cancer Metastasis Rev., 13, 223-233.
-
(1994)
Cancer Metastasis Rev.
, vol.13
, pp. 223-233
-
-
Bradley, G.1
Ling, V.2
-
5
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar,S.V., Dey,S., Hrycyna,C.A., Ramachandra,M., Pastan,I. and Gottesman,M.M. (1999) Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu. Rev. Pharmacol. Toxicol., 39, 361-398.
-
(1999)
Annu. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
6
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut,F., Tsuruo,T., Hamada,H., Gottesman,M.M., Pastan,I. and Willingham,M.C. (1987) Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl Acad. Sci. USA, 84, 7735-7738.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
7
-
-
0036892827
-
MDR1 inhibition: Less resistance or less relevance?
-
Garraway,L.A. and Chabner,B. (2002) MDR1 inhibition: less resistance or less relevance? Eur. J. Cancer, 38, 2337-2340.
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 2337-2340
-
-
Garraway, L.A.1
Chabner, B.2
-
8
-
-
0031005627
-
Acute myeloid leukemia in the elderly: Assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy
-
A Southwest Oncology Group study
-
Leith,C.P., Kopecky,K.J., Godwin,J., McConnell,T., Slovak,M.L., Chen,I.M., Head,D.R., Appelbaum,F.R. and Willman,C.L. (1997) Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study. Blood, 89, 3323-3329.
-
(1997)
Blood
, vol.89
, pp. 3323-3329
-
-
Leith, C.P.1
Kopecky, K.J.2
Godwin, J.3
McConnell, T.4
Slovak, M.L.5
Chen, I.M.6
Head, D.R.7
Appelbaum, F.R.8
Willman, C.L.9
-
9
-
-
0031728267
-
Multidrug resistance: Clinical relevance in solid tumours and strategies for circumvention
-
Kaye,S.B. (1998) Multidrug resistance: clinical relevance in solid tumours and strategies for circumvention. Curr. Opin. Oncol., 10 (Suppl. 1), S15-S19.
-
(1998)
Curr. Opin. Oncol.
, vol.10
, Issue.SUPPL. 1
-
-
Kaye, S.B.1
-
10
-
-
10744231610
-
Effect of PSC 833, an inhibitor of P-glycoprotein on N-methyl-N-nitrosourea induced mammary carcinogenesis in rats
-
Kankesan,J., Vanama,R., Yusuf,A., Thiessen,J.J., Ling,V., Rao,P.M., Rajalakshmi,S. and Sarma,D.S. (2003) Effect of PSC 833, an inhibitor of P-glycoprotein on N-methyl-N-nitrosourea induced mammary carcinogenesis in rats. Carcinogenesis, 24, 1977-1984.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1977-1984
-
-
Kankesan, J.1
Vanama, R.2
Yusuf, A.3
Thiessen, J.J.4
Ling, V.5
Rao, P.M.6
Rajalakshmi, S.7
Sarma, D.S.8
-
11
-
-
0142058819
-
Effect of PSC 833, a potent inhibitor of P-glycoprotein, on the growth of astrocytoma cells in vitro
-
Sadanand, V., Kankesan,J., Yusuf,A., Stewart,C., Rutka,J.T., Thiessen,J.J., Ling,V., Rao,P.M., Rajalakshmi,S. and Sarma,D.S. (2003) Effect of PSC 833, a potent inhibitor of P-glycoprotein, on the growth of astrocytoma cells in vitro. Cancer Lett., 198, 21-27.
-
(2003)
Cancer Lett.
, vol.198
, pp. 21-27
-
-
Sadanand, V.1
Kankesan, J.2
Yusuf, A.3
Stewart, C.4
Rutka, J.T.5
Thiessen, J.J.6
Ling, V.7
Rao, P.M.8
Rajalakshmi, S.9
Sarma, D.S.10
-
12
-
-
0042167430
-
P-glycoprotein inhibitors and their screening: A perspective from bioavailability enhancement
-
Varma,M.V., Ashokraj,Y., Dey,C.S. and Panchagnula,R. (2003) P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement. Pharmacol. Res., 48, 347-359.
-
(2003)
Pharmacol. Res.
, vol.48
, pp. 347-359
-
-
Varma, M.V.1
Ashokraj, Y.2
Dey, C.S.3
Panchagnula, R.4
-
13
-
-
0034496578
-
Does P-glycoprotein play a role in anticancer drug pharmacokinetics?
-
Sparreboom,A. and Nooter,K. (2000) Does P-glycoprotein play a role in anticancer drug pharmacokinetics? Drug Resist. Updat., 3, 357-363.
-
(2000)
Drug Resist. Updat.
, vol.3
, pp. 357-363
-
-
Sparreboom, A.1
Nooter, K.2
-
14
-
-
0037733977
-
Antisense technologies. Improvement through novel chemical modifications
-
Kurreck,J. (2003) Antisense technologies. Improvement through novel chemical modifications. Eur. J. Biochem., 270, 1628-1644.
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1628-1644
-
-
Kurreck, J.1
-
15
-
-
1542269161
-
Progress in antisense technology
-
Crooke,S.T. (2004) Progress in antisense technology. Annu. Rev. Med., 55, 61-95.
-
(2004)
Annu. Rev. Med.
, vol.55
, pp. 61-95
-
-
Crooke, S.T.1
-
16
-
-
0035502598
-
Antisense and/or immunostimulatory oligonucleotide therapeutics
-
Agrawal,S. and Kandimalla,E.R. (2001) Antisense and/or immunostimulatory oligonucleotide therapeutics. Curr. Cancer Drug Targets, 1, 197-209.
-
(2001)
Curr. Cancer Drug Targets
, vol.1
, pp. 197-209
-
-
Agrawal, S.1
Kandimalla, E.R.2
-
17
-
-
0033958635
-
Antisense therapeutics: Is it as simple as complementary base recognition?
-
Agrawal,S. and Kandimalla,E.R. (2000) Antisense therapeutics: is it as simple as complementary base recognition? Mol. Med. Today, 6, 72-81.
-
(2000)
Mol. Med. Today
, vol.6
, pp. 72-81
-
-
Agrawal, S.1
Kandimalla, E.R.2
-
18
-
-
0000015743
-
Antisense oligonucleotides: Basic concepts and mechanisms
-
Dias,N. and Stein,C.A. (2002) Antisense oligonucleotides: basic concepts and mechanisms. Mol. Cancer Ther., 1, 347-355.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 347-355
-
-
Dias, N.1
Stein, C.A.2
-
19
-
-
0035433920
-
Antisense that comes naturally
-
Stein,C.A. (2001) Antisense that comes naturally. Nat. Biotechnol., 19, 737-738.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 737-738
-
-
Stein, C.A.1
-
20
-
-
1642430704
-
Antisense oligonucleotide-based therapeutics for cancer
-
Dean,N.M. and Bennett,C.F. (2003) Antisense oligonucleotide-based therapeutics for cancer. Oncogene, 22, 9087-9096.
-
(2003)
Oncogene
, vol.22
, pp. 9087-9096
-
-
Dean, N.M.1
Bennett, C.F.2
-
21
-
-
0038540242
-
Antisense therapeutics: From theory to clinical practice
-
Pirollo,K.F., Rait,A., Sleer,L.S. and Chang,E.H. (2003) Antisense therapeutics: from theory to clinical practice. Pharmacol. Ther., 99, 55-77.
-
(2003)
Pharmacol. Ther.
, vol.99
, pp. 55-77
-
-
Pirollo, K.F.1
Rait, A.2
Sleer, L.S.3
Chang, E.H.4
-
22
-
-
0033812002
-
Heterocyclic modifications of oligonucleotides and antisense technology
-
Herdewijn,P. (2000) Heterocyclic modifications of oligonucleotides and antisense technology. Antisense Nucleic Acid Drug Dev., 10, 297-310.
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, pp. 297-310
-
-
Herdewijn, P.1
-
23
-
-
0032473890
-
LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition
-
Koshkin,A.A., Singh,S.K., Nielsen,P., Rajwanshi,V.K., Kumar,R., Meldgaard,M., Olsen,C.E. and Wengel,J. (1998) LNA (Locked Nucleic Acids): synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition. Tetrahedron, 54, 3607-3630.
-
(1998)
Tetrahedron
, vol.54
, pp. 3607-3630
-
-
Koshkin, A.A.1
Singh, S.K.2
Nielsen, P.3
Rajwanshi, V.K.4
Kumar, R.5
Meldgaard, M.6
Olsen, C.E.7
Wengel, J.8
-
24
-
-
0026341239
-
Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide
-
Nielsen,P.E., Egholm,M., Berg,R.H. and Buchardt,O. (1991) Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science, 254, 1497-1500.
-
(1991)
Science
, vol.254
, pp. 1497-1500
-
-
Nielsen, P.E.1
Egholm, M.2
Berg, R.H.3
Buchardt, O.4
-
25
-
-
0034644387
-
Cyclohexene nucleic acids (CeNA): Serum stable oligonucleotides that activate RNase H and increase duplex stability with complementary RNA
-
Wang,J., Verbeure,B., Luyten,I., Lescrinier,E., Froeyen,M., Hendrix,C., Rosemeyer,H., Seela,F., Van Aerschot,A. and Herdewijn,P. (2000) Cyclohexene nucleic acids (CeNA): serum stable oligonucleotides that activate RNase H and increase duplex stability with complementary RNA. J. Am. Chem. Soc., 122, 8595-8602.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 8595-8602
-
-
Wang, J.1
Verbeure, B.2
Luyten, I.3
Lescrinier, E.4
Froeyen, M.5
Hendrix, C.6
Rosemeyer, H.7
Seela, F.8
Van Aerschot, A.9
Herdewijn, P.10
-
26
-
-
0023566958
-
A new approach to chemotherapy based on molecular biology and nucleic acid chemistry: Matagen (masking tape for gene expression)
-
Miller,P.S. and Ts'o,P.O. (1987) A new approach to chemotherapy based on molecular biology and nucleic acid chemistry: matagen (masking tape for gene expression). Anticancer Drug Des., 2, 117-128.
-
(1987)
Anticancer Drug Des.
, vol.2
, pp. 117-128
-
-
Miller, P.S.1
Ts'o, P.O.2
-
27
-
-
0032697942
-
A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides
-
Levin,A.A. (1999) A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim. Biophys. Acta, 1489, 69-84.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 69-84
-
-
Levin, A.A.1
-
28
-
-
0035962892
-
A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H
-
Zamaratski,E., Pradeepkumar,P.I. and Chattopadhyaya,J. (2001) A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H. J. Biochem. Biophys. Methods, 48, 189-208.
-
(2001)
J. Biochem. Biophys. Methods
, vol.48
, pp. 189-208
-
-
Zamaratski, E.1
Pradeepkumar, P.I.2
Chattopadhyaya, J.3
-
29
-
-
0032700357
-
Antisense properties of peptide nucleic acid
-
Larsen,H.J., Bentin,T. and Nielsen,P.E. (1999) Antisense properties of peptide nucleic acid. Biochim. Biophys. Acta, 1489, 159-166.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 159-166
-
-
Larsen, H.J.1
Bentin, T.2
Nielsen, P.E.3
-
30
-
-
0031948835
-
Mixed backbone oligonucleotides: Improvement in oligonucleotide-induced toxicity in vivo
-
Agrawal,S. and Zhao,Q. (1998) Mixed backbone oligonucleotides: improvement in oligonucleotide-induced toxicity in vivo. Antisense Nucleic Acid Drug Dev., 8, 135-139.
-
(1998)
Antisense Nucleic Acid Drug Dev.
, vol.8
, pp. 135-139
-
-
Agrawal, S.1
Zhao, Q.2
-
31
-
-
0030020391
-
Minimally modified oligonucleotides-combination of end-capping and pyrimidine-protection
-
Peyman,A. and Uhlmann,E. (1996) Minimally modified oligonucleotides-combination of end-capping and pyrimidine-protection. Biol. Chem. Hoppe-Seyler, 377, 67-70.
-
(1996)
Biol. Chem. Hoppe-Seyler
, vol.377
, pp. 67-70
-
-
Peyman, A.1
Uhlmann, E.2
-
32
-
-
0034121346
-
3′-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: Synthesis and anti-ras activity in radiation-resistant cells
-
Rait,A., Pirollo,K., Will,D.W., Peyman,A., Rait,V., Uhlmann,E. and Chang,E.H. (2000) 3′-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: synthesis and anti-ras activity in radiation-resistant cells. Bioconjug. Chem., 11, 153-160.
-
(2000)
Bioconjug. Chem.
, vol.11
, pp. 153-160
-
-
Rait, A.1
Pirollo, K.2
Will, D.W.3
Peyman, A.4
Rait, V.5
Uhlmann, E.6
Chang, E.H.7
-
33
-
-
0033576279
-
Syntheses of alternating oligo-2′-O-methylribonucleoside methylphosphonates and their interactions with HIV TAR RNA
-
Hamma,T. and Miller,P.S. (1999) Syntheses of alternating oligo-2′-O-methylribonucleoside methylphosphonates and their interactions with HIV TAR RNA. Biochemistry, 38, 15333-15342.
-
(1999)
Biochemistry
, vol.38
, pp. 15333-15342
-
-
Hamma, T.1
Miller, P.S.2
-
34
-
-
0031849610
-
Novel chemically modified oligonucleotides provide potent inhibition of P-glycoprotein expression
-
Alahari,S.K., DeLong,R., Fisher,M.H., Dean,N.M., Viliet,P. and Juliano,R.L. (1998) Novel chemically modified oligonucleotides provide potent inhibition of P-glycoprotein expression. J. Pharm. Exp. Ther., 286, 419-428.
-
(1998)
J. Pharm. Exp. Ther.
, vol.286
, pp. 419-428
-
-
Alahari, S.K.1
DeLong, R.2
Fisher, M.H.3
Dean, N.M.4
Viliet, P.5
Juliano, R.L.6
-
35
-
-
0029966767
-
Inhibition of expression of the multidrug resistance-associated P-glycoprotein of by phosphorothioate and 5′ cholesterol-conjugated phosphorothioate antisense oligonucleotides
-
Alahari,S.K., Dean,N.M., Fisher,M.H., Delong,R., Manoharan,M., Tivel,K.L. and Juliano,R.L. (1996) Inhibition of expression of the multidrug resistance-associated P-glycoprotein of by phosphorothioate and 5′ cholesterol-conjugated phosphorothioate antisense oligonucleotides. Mol. Pharmacol., 50, 808-819.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 808-819
-
-
Alahari, S.K.1
Dean, N.M.2
Fisher, M.H.3
Delong, R.4
Manoharan, M.5
Tivel, K.L.6
Juliano, R.L.7
-
36
-
-
0037383444
-
Ribozymes: Recent advances in the development of RNA tools
-
Puerta-Fernandez,E., Romero-Lopez,C., Barroso-delJesus,A. and Berzal-Herranz,A. (2003) Ribozymes: recent advances in the development of RNA tools. FEMS Microbiol. Rev., 27, 75-97.
-
(2003)
FEMS Microbiol. Rev.
, vol.27
, pp. 75-97
-
-
Puerta-Fernandez, E.1
Romero-Lopez, C.2
Barroso-del Jesus, A.3
Berzal-Herranz, A.4
-
37
-
-
0037062951
-
RNA interference
-
Hannon,G.J. (2002) RNA interference. Nature, 418, 244-251.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
38
-
-
0346024002
-
Therapeutic siRNAs
-
Sioud,M. (2004) Therapeutic siRNAs. Trends Pharmacol. Sci., 25, 22-28.
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, pp. 22-28
-
-
Sioud, M.1
-
39
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
Harborth,J., Elbashir,S.M., Vandenburgh,K., Manninga,H., Scaringe,S.A., Weber,K. and Tuschl,T. (2003) Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense Nucleic Acid Drug Dev., 13, 83-105.
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
Manninga, H.4
Scaringe, S.A.5
Weber, K.6
Tuschl, T.7
-
40
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire,A., Xu,S., Montgomery,M.K., Kostas,S.A., Driver,S.E. and Mello,C.C. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 391, 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
41
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir,S.M., Harborth,J., Lendeckel,W., Yalcin,A., Weber,K. and Tuschl,T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 411, 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
42
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub,T.R., Slonim,D.K., Tamayo,P., Huard,C., Gaasenbeek,M., Mesirov,J.P., Coller,H., Loh,M.L., Downing,J.R., Caligiuri,M.A. et al. (1999) Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science, 286, 531-537.
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
Slonim, D.K.2
Tamayo, P.3
Huard, C.4
Gaasenbeek, M.5
Mesirov, J.P.6
Coller, H.7
Loh, M.L.8
Downing, J.R.9
Caligiuri, M.A.10
-
43
-
-
0038121109
-
Specificity of short interfering RNA determined through gene expression signatures
-
Semizarov,D., Frost,L., Sarthy,A., Kroeger,P., Halbert,D.N. and Fesik,S.W. (2003) Specificity of short interfering RNA determined through gene expression signatures. Proc. Natl Acad. Sci. USA, 100, 6347-6352.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6347-6352
-
-
Semizarov, D.1
Frost, L.2
Sarthy, A.3
Kroeger, P.4
Halbert, D.N.5
Fesik, S.W.6
-
44
-
-
10744219688
-
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
-
Scacheri,P.C., Rozenblatt-Rosen,O., Caplen,N.J., Wolfsberg,T.G., Umayam,L., Lee,J.C., Hughes,C.M., Shanmugam,K.S., Bhattacharjee,A., Meyerson,M. et al. (2004) Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc. Natl Acad. Sci. USA, 101, 1892-1897.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1892-1897
-
-
Scacheri, P.C.1
Rozenblatt-Rosen, O.2
Caplen, N.J.3
Wolfsberg, T.G.4
Umayam, L.5
Lee, J.C.6
Hughes, C.M.7
Shanmugam, K.S.8
Bhattacharjee, A.9
Meyerson, M.10
-
45
-
-
0344926320
-
Cationic liposome-mediated delivery of siRNAs in adult mice
-
Sioud,M. and Sorensen,D.R. (2003) Cationic liposome-mediated delivery of siRNAs in adult mice. Biochem. Biophys. Res. Commun., 312, 1220-1225.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.312
, pp. 1220-1225
-
-
Sioud, M.1
Sorensen, D.R.2
-
46
-
-
0042872962
-
Effect of MDR1 phosphorothioate antisense oligodeoxynucleotides in multidrug-resistant human tumor cell lines and xenografts
-
Ramachandran,C. and Wellham,L.L. (2003) Effect of MDR1 phosphorothioate antisense oligodeoxynucleotides in multidrug-resistant human tumor cell lines and xenografts. Anticancer Res., 23, 2681-2690.
-
(2003)
Anticancer Res.
, vol.23
, pp. 2681-2690
-
-
Ramachandran, C.1
Wellham, L.L.2
-
47
-
-
0037336279
-
Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin
-
Pakunlu,R.I., Cook,T.J. and Minko,T. (2003) Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin. Pharm. Res., 20, 351-359.
-
(2003)
Pharm. Res.
, vol.20
, pp. 351-359
-
-
Pakunlu, R.I.1
Cook, T.J.2
Minko, T.3
-
48
-
-
0037333165
-
Minimally modified phosphodiester antisense oligodeoxyribonucleotide directed against the multidrug resistance gene mdr1
-
Brigui,I., Djavanbakht-Samani,T., Jolles,B., Pigaglio,S. and Laigle,A. (2003) Minimally modified phosphodiester antisense oligodeoxyribonucleotide directed against the multidrug resistance gene mdr1. Biochem. Pharmacol., 65, 747-754.
-
(2003)
Biochem. Pharmacol.
, vol.65
, pp. 747-754
-
-
Brigui, I.1
Djavanbakht-Samani, T.2
Jolles, B.3
Pigaglio, S.4
Laigle, A.5
-
49
-
-
0034807988
-
Reversing drug resistance in the ovarian carcinoma cell line SKOV3/mdr1 in vitro by antisense oligodeoxynucleotides
-
Pan,L., Tong,Y., Jin,Y., Zhou,S., Zhang,Y., Yang,X. and Mao,N. (2001) Reversing drug resistance in the ovarian carcinoma cell line SKOV3/mdr1 in vitro by antisense oligodeoxynucleotides. Chin. Med. J. (Engl), 114, 929-932.
-
(2001)
Chin. Med. J. (Engl)
, vol.114
, pp. 929-932
-
-
Pan, L.1
Tong, Y.2
Jin, Y.3
Zhou, S.4
Zhang, Y.5
Yang, X.6
Mao, N.7
-
50
-
-
0037151062
-
Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis
-
Fisher,A.A., Ye,D., Sergueev,D.S., Fisher,M.H., Shaw,B.R. and Juliano,R.L. (2002) Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis. J. Biol. Chem., 277, 22980-22984.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22980-22984
-
-
Fisher, A.A.1
Ye, D.2
Sergueev, D.S.3
Fisher, M.H.4
Shaw, B.R.5
Juliano, R.L.6
-
51
-
-
0028091989
-
Inhibition of MDR1 gene expression by antimessenger oligonucleotides lowers multiple drug resistance
-
Quattrone,A., Papucci,L., Morganti,M., Coronnello,M., Mini,E., Mazzei,T., Colonna,F.P., Garbesi,A. and Capaccioli,S. (1994) Inhibition of MDR1 gene expression by antimessenger oligonucleotides lowers multiple drug resistance. Oncol. Res., 6, 311-320.
-
(1994)
Oncol. Res.
, vol.6
, pp. 311-320
-
-
Quattrone, A.1
Papucci, L.2
Morganti, M.3
Coronnello, M.4
Mini, E.5
Mazzei, T.6
Colonna, F.P.7
Garbesi, A.8
Capaccioli, S.9
-
52
-
-
0035463543
-
Novel approaches to reversing anti-cancer drug resistance using gene-specific therapeutics
-
Kobayashi,H., Takemura,Y. and Miyachi,H. (2001) Novel approaches to reversing anti-cancer drug resistance using gene-specific therapeutics. Hum. Cell, 14, 172-184.
-
(2001)
Hum. Cell
, vol.14
, pp. 172-184
-
-
Kobayashi, H.1
Takemura, Y.2
Miyachi, H.3
-
53
-
-
0036834161
-
Reversal of drug resistance using hammerhead ribozymes against multidrug resistance-associated protein and multidrug resistance 1 gene
-
Nagata,J., Kijima,H., Hatanaka,H., Asai,S., Miyachi,H., Abe,Y., Yamazaki,H., Nakamura,M., Watanabe,N., Mine,T. et al. (2002) Reversal of drug resistance using hammerhead ribozymes against multidrug resistance-associated protein and multidrug resistance 1 gene. Int. J. Oncol., 21, 1021-1026.
-
(2002)
Int. J. Oncol.
, vol.21
, pp. 1021-1026
-
-
Nagata, J.1
Kijima, H.2
Hatanaka, H.3
Asai, S.4
Miyachi, H.5
Abe, Y.6
Yamazaki, H.7
Nakamura, M.8
Watanabe, N.9
Mine, T.10
-
54
-
-
0141484591
-
Catalytic DNA and RNA for targeting MDR1 mRNA
-
Kuznetsova,M., Fokina,A., Lukin,M., Repkova,M., Venyaminova,A. and Vlassov,V. (2003) Catalytic DNA and RNA for targeting MDR1 mRNA. Nucleosides Nucleotides Nucleic Acids, 22, 1521-1523.
-
(2003)
Nucleosides Nucleotides Nucleic Acids
, vol.22
, pp. 1521-1523
-
-
Kuznetsova, M.1
Fokina, A.2
Lukin, M.3
Repkova, M.4
Venyaminova, A.5
Vlassov, V.6
-
55
-
-
0027452745
-
Cleavage of human MDR1 mRNA by a hammerhead ribozyme
-
Kobayashi,H., Dorai,T., Holland,J.F. and Ohnuma,T. (1993) Cleavage of human MDR1 mRNA by a hammerhead ribozyme. FEBS Lett., 319, 71-74.
-
(1993)
FEBS Lett.
, vol.319
, pp. 71-74
-
-
Kobayashi, H.1
Dorai, T.2
Holland, J.F.3
Ohnuma, T.4
-
56
-
-
0029565726
-
Similar cleavage efficiencies of an oligoribonucleotide substrate and an mdr1 mRNA segment by a hammerhead ribozyme
-
Holm,P.S., Dietel,M. and Krupp,G. (1995) Similar cleavage efficiencies of an oligoribonucleotide substrate and an mdr1 mRNA segment by a hammerhead ribozyme. Gene, 167, 221-225.
-
(1995)
Gene
, vol.167
, pp. 221-225
-
-
Holm, P.S.1
Dietel, M.2
Krupp, G.3
-
57
-
-
0037380839
-
Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells
-
Wu,H., Hait,W.N. and Yang,J.M. (2003) Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res., 63, 1515-1519.
-
(2003)
Cancer Res.
, vol.63
, pp. 1515-1519
-
-
Wu, H.1
Hait, W.N.2
Yang, J.M.3
-
58
-
-
0037526598
-
Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi)
-
Nieth,C., Priebsch,A., Stege,A. and Lage,H. (2003) Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi). FEBS Lett., 545, 144-150.
-
(2003)
FEBS Lett.
, vol.545
, pp. 144-150
-
-
Nieth, C.1
Priebsch, A.2
Stege, A.3
Lage, H.4
-
59
-
-
0030805280
-
1′,5′-anhydrohexitol oligonucleotides: Hybridisation and strand displacement with oligoribonucleotides, interaction with RNase H and HIV reverse transcriptase
-
Hendrix,C., Rosemeyer,H., De Bouvere,B., Van Aerschot,A., Seela,F. and Herdewijn,P. (1997) 1′,5′-anhydrohexitol oligonucleotides: hybridisation and strand displacement with oligoribonucleotides, interaction with RNase H and HIV reverse transcriptase. Chemistry - A Eur. J., 3, 1513-1520.
-
(1997)
Chemistry - A Eur. J.
, vol.3
, pp. 1513-1520
-
-
Hendrix, C.1
Rosemeyer, H.2
De Bouvere, B.3
Van Aerschot, A.4
Seela, F.5
Herdewijn, P.6
-
60
-
-
0033826781
-
Solution structure of a HNA-RNA hybrid
-
Lescrinier,E., Esnouf,R., Schraml,J., Busson,R., Heus,H.A., Hilbers,C.W. and Herdewijn,P. (2000) Solution structure of a HNA-RNA hybrid. Chem. Biol., 7, 719-731.
-
(2000)
Chem. Biol.
, vol.7
, pp. 719-731
-
-
Lescrinier, E.1
Esnouf, R.2
Schraml, J.3
Busson, R.4
Heus, H.A.5
Hilbers, C.W.6
Herdewijn, P.7
-
61
-
-
17644444816
-
Biological activity of hexitol nucleic acids targeted at Ha-ras and intracellular adhesion molecule-1 mRNA
-
Vandermeeren,M., Preveral,S., Janssens,S., Geysen,J., Saison-Behmoaras,E., Van Aerschot,A. and Herdewijn,P. (2000) Biological activity of hexitol nucleic acids targeted at Ha-ras and intracellular adhesion molecule-1 mRNA. Biochem. Pharmacol., 59, 655-663.
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 655-663
-
-
Vandermeeren, M.1
Preveral, S.2
Janssens, S.3
Geysen, J.4
Saison-Behmoaras, E.5
Van Aerschot, A.6
Herdewijn, P.7
-
62
-
-
0032863109
-
Antimalarial antisense activity of hexitol nucleic acids
-
Flores,M.V., Atkins,D., Stewart,T.S., Van Aerschot,A. and Herdewijn,P. (1999) Antimalarial antisense activity of hexitol nucleic acids. Parasitol. Res., 85, 864-866.
-
(1999)
Parasitol. Res.
, vol.85
, pp. 864-866
-
-
Flores, M.V.1
Atkins, D.2
Stewart, T.S.3
Van Aerschot, A.4
Herdewijn, P.5
-
63
-
-
33748833320
-
Improved synthesis of anhydrohexitol building blocks for oligonucleotide synthesis
-
De Bouvere,B., Kerremans,L., Rozenski,J., Janssen,G., Van Aerschot,A., Claes,P., Busson,R. and Herdewijn,P. (1997) Improved synthesis of anhydrohexitol building blocks for oligonucleotide synthesis. Liebigs Ann.-Rec., 1453-1461.
-
(1997)
Liebigs Ann.-Rec.
, pp. 1453-1461
-
-
De Douvere, B.1
Kerremans, L.2
Rozenski, J.3
Janssen, G.4
Van Aerschot, A.5
Claes, P.6
Busson, R.7
Herdewijn, P.8
-
64
-
-
0032503508
-
Molecular dynamics simulation to investigate differences in minor groove hydration of HNA/RNA hybrids as compared to HNA/DNA complexes
-
DeWinter,H., Lescrinier,E., Van Aerschot,A. and Herdewijn,P. (1998) Molecular dynamics simulation to investigate differences in minor groove hydration of HNA/RNA hybrids as compared to HNA/DNA complexes. J. Am. Chem. Soc., 120, 5381-5394.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 5381-5394
-
-
DeWinter, H.1
Lescrinier, E.2
Van Aerschot, A.3
Herdewijn, P.4
-
65
-
-
0031037550
-
Antisense oligonucleotides targeting human protein kinase C-alpha inhibit phorbol ester-induced reduction of bradykinin-evoked calcium mobilization in A549 cells
-
Levesque,L., Dean,N.M., Sasmor,H. and Crooke,S.T. (1997) Antisense oligonucleotides targeting human protein kinase C-alpha inhibit phorbol ester-induced reduction of bradykinin-evoked calcium mobilization in A549 cells. Mol. Pharmacol., 51, 209-216.
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 209-216
-
-
Levesque, L.1
Dean, N.M.2
Sasmor, H.3
Crooke, S.T.4
-
66
-
-
0024787142
-
A new vector using the human multidrug resistance gene as a selectable marker enables overexpression of foreign genes in eukaryotic cells
-
Kane,S.E., Reinhard,D.H., Fordis,C.M., Pastan,I. and Gottesman,M.M. (1989) A new vector using the human multidrug resistance gene as a selectable marker enables overexpression of foreign genes in eukaryotic cells. Gene, 84, 439-446.
-
(1989)
Gene
, vol.84
, pp. 439-446
-
-
Kane, S.E.1
Reinhard, D.H.2
Fordis, C.M.3
Pastan, I.4
Gottesman, M.M.5
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