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Volumn 36, Issue 12, 2003, Pages 1585-1592

A review of low-dose ritonavir in protease inhibitor combination therapy

Author keywords

[No Author keywords available]

Indexed keywords

AMPRENAVIR; CYTOCHROME P450 3A4; EFAVIRENZ; INDINAVIR; LOPINAVIR; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; CYP3A PROTEIN, HUMAN; CYTOCHROME P450;

EID: 0037871892     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/375233     Document Type: Review
Times cited : (144)

References (88)
  • 1
    • 15444377672 scopus 로고    scopus 로고
    • Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
    • Molla A, Korneyeva M, Gao Q, et al. Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nat Med 1996; 2:760-6.
    • (1996) Nat Med , vol.2 , pp. 760-766
    • Molla, A.1    Korneyeva, M.2    Gao, Q.3
  • 2
    • 0031035968 scopus 로고    scopus 로고
    • Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir
    • Kempf DJ, Marsh KC, Kumar G, et al. Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir. Antimicrob Agents Chemother 1997;41:654-60.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 654-660
    • Kempf, D.J.1    Marsh, K.C.2    Kumar, G.3
  • 3
    • 0031882580 scopus 로고    scopus 로고
    • The role of combinations of HIV protease inhibitors in the management of persons with HIV infection
    • Moyle G. The role of combinations of HIV protease inhibitors in the management of persons with HIV infection. Expert Opinion on Investigational Drugs 1998; 7:413-26.
    • (1998) Expert Opinion on Investigational Drugs , vol.7 , pp. 413-426
    • Moyle, G.1
  • 4
    • 0003352345 scopus 로고    scopus 로고
    • Saquinavir soft gel capsules (Fortovase): Pharmacokinetics and drug interactions
    • abstract 354. (Chicago). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Buss N. Saquinavir soft gel capsules (Fortovase): pharmacokinetics and drug interactions [abstract 354]. In: Program and abstracts of the 5th Conference on Retroviruses and Opportunistic Infections (Chicago). Alexandria, VA: Foundation for Retroviruses and Human Health, 1998: 145.
    • (1998) Program and Abstracts of the 5th Conference on Retroviruses and Opportunistic Infections , pp. 145
    • Buss, N.1
  • 6
    • 0035717630 scopus 로고    scopus 로고
    • Combination of protease inhibitors for the treatment of HIV-1-infected patients: A review of pharmacokinetics and clinical experience
    • van Heeswijk RP, Veldkamp A, Mulder JW, et al. Combination of protease inhibitors for the treatment of HIV-1-infected patients: a review of pharmacokinetics and clinical experience. Antivir Ther 2001; 6:201-29.
    • (2001) Antivir Ther , vol.6 , pp. 201-229
    • Van Heeswijk, R.P.1    Veldkamp, A.2    Mulder, J.W.3
  • 7
    • 0036204259 scopus 로고    scopus 로고
    • Low-dose ritonavir for protease inhibitor pharmacokinetic enhancement
    • Rathbun RC, Rossi DR. Low-dose ritonavir for protease inhibitor pharmacokinetic enhancement. Ann Pharmacother 2002; 36:702-6.
    • (2002) Ann Pharmacother , vol.36 , pp. 702-706
    • Rathbun, R.C.1    Rossi, D.R.2
  • 8
    • 0035198762 scopus 로고    scopus 로고
    • Principles and practice of HIV-protease inhibitor pharmacoenhancement
    • Moyle GJ, Back D. Principles and practice of HIV-protease inhibitor pharmacoenhancement. HIV Med 2001; 2:105-13.
    • (2001) HIV Med , vol.2 , pp. 105-113
    • Moyle, G.J.1    Back, D.2
  • 9
    • 0032971472 scopus 로고    scopus 로고
    • Ritonavir and saquinavir combination therapy for the treatment of HIV infection
    • Cameron DW, Japour AJ, Xu Y, et al. Ritonavir and saquinavir combination therapy for the treatment of HIV infection. AIDS 1999; 13:213-24.
    • (1999) AIDS , vol.13 , pp. 213-224
    • Cameron, D.W.1    Japour, A.J.2    Xu, Y.3
  • 10
    • 0038510303 scopus 로고    scopus 로고
    • Durability of ritonavir (RTV) plus saquinavir (SQV) dual protease inhibitor therapy in HIV infections: 5-Year follow-up
    • abstract 550-T. (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Cameron DW, Angel JB, Ryan J, et al. Durability of ritonavir (RTV) plus saquinavir (SQV) dual protease inhibitor therapy in HIV infections: 5-year follow-up [abstract 550-T]. In: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • Cameron, D.W.1    Angel, J.B.2    Ryan, J.3
  • 11
    • 0032732512 scopus 로고    scopus 로고
    • The relationship between ritonavir plasma levels and side-effects: Implications for therapeutic drug monitoring
    • Gatti G, Di Biagio A, Casazza R, et al. The relationship between ritonavir plasma levels and side-effects: implications for therapeutic drug monitoring. AIDS 1999; 13:2083-9.
    • (1999) AIDS , vol.13 , pp. 2083-2089
    • Gatti, G.1    Di Biagio, A.2    Casazza, R.3
  • 12
    • 0032710406 scopus 로고    scopus 로고
    • The steady-state plasma pharmacokinetics of indinavir alone and in combination with a low dose of ritonavir in twice daily dosing regimens in HIV-1-infected individuals
    • van Heeswijk RP, Veldkamp AI, Hoetelmans RM, et al. The steady-state plasma pharmacokinetics of indinavir alone and in combination with a low dose of ritonavir in twice daily dosing regimens in HIV-1-infected individuals. AIDS 1999; 13:F95-9.
    • (1999) AIDS , vol.13
    • Van Heeswijk, R.P.1    Veldkamp, A.I.2    Hoetelmans, R.M.3
  • 13
    • 0035424509 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of twice-daily dosing of saquinavir plus ritonavir in HIV-1-infected individuals
    • Veldkamp AI, van Heeswijk RP, Mulder JW, et al. Steady-state pharmacokinetics of twice-daily dosing of saquinavir plus ritonavir in HIV-1-infected individuals. J Acquir Immune Defic Syndr 2001; 27:344-9.
    • (2001) J Acquir Immune Defic Syndr , vol.27 , pp. 344-349
    • Veldkamp, A.I.1    Van Heeswijk, R.P.2    Mulder, J.W.3
  • 14
    • 0033802649 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of once-daily regimens of soft-gel capsule saquinavir plus minidose ritonavir in human immunodeficiency virus-negative adults
    • Kilby JM, Sfakianos G, Gizzi N, et al. Safety and pharmacokinetics of once-daily regimens of soft-gel capsule saquinavir plus minidose ritonavir in human immunodeficiency virus-negative adults. Antimicrob Agents Chemother 2000; 44:2672-8.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2672-2678
    • Kilby, J.M.1    Sfakianos, G.2    Gizzi, N.3
  • 15
    • 0037719325 scopus 로고    scopus 로고
    • Effect of simultaneous or staggered dosing of saquinavir (SQV), ritonavir (RTV), and neffinavir (NFV) on pharmacokinetic (PK) interactions
    • abstract 76. (San Francisco). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Blaschke T, Flexner C, Sheiner L, Rosenkranz S. Effect of simultaneous or staggered dosing of saquinavir (SQV), ritonavir (RTV), and neffinavir (NFV) on pharmacokinetic (PK) interactions [abstract 76]. In: Program and abstracts of the 7th Conference on Retroviruses and Opportunistic Infections (San Francisco). Alexandria, VA: Foundation for Retroviruses and Human Health, 2000.
    • (2000) Program and Abstracts of the 7th Conference on Retroviruses and Opportunistic Infections
    • Blaschke, T.1    Flexner, C.2    Sheiner, L.3    Rosenkranz, S.4
  • 16
    • 0036556381 scopus 로고    scopus 로고
    • Iatrogenic Cushing's syndrome in an HIV-infected patient treated with inhaled corticosteroids (fluticasone propionate) and low dose ritonavir enhanced PI containing regimen
    • Clevenbergh P, Corcostegui M, Gerard D, et al. Iatrogenic Cushing's syndrome in an HIV-infected patient treated with inhaled corticosteroids (fluticasone propionate) and low dose ritonavir enhanced PI containing regimen. J Infect 2002; 44:194-5.
    • (2002) J Infect , vol.44 , pp. 194-195
    • Clevenbergh, P.1    Corcostegui, M.2    Gerard, D.3
  • 17
    • 0036785221 scopus 로고    scopus 로고
    • Interactions between recreational drugs and antiretroviral agents
    • Antoniou T, Tseng AL. Interactions between recreational drugs and antiretroviral agents. Ann Pharmacother 2002; 36:1598-613.
    • (2002) Ann Pharmacother , vol.36 , pp. 1598-1613
    • Antoniou, T.1    Tseng, A.L.2
  • 18
    • 0035967245 scopus 로고    scopus 로고
    • Interactions among drugs for HIV and opportunistic infections
    • Piscitelli SC, Gallicano KD, Interactions among drugs for HIV and opportunistic infections. N Engl J Med 2001; 344:984-96.
    • (2001) N Engl J Med , vol.344 , pp. 984-996
    • Piscitelli, S.C.1    Gallicano, K.D.2
  • 19
    • 0036162141 scopus 로고    scopus 로고
    • The influence of efavirenz on the pharmacokinetics of a twice-daily combination of indinavir and low-dose ritonavir in healthy volunteers
    • Aarnoutse RE, Grintjes KJ, Telgt DS, et al. The influence of efavirenz on the pharmacokinetics of a twice-daily combination of indinavir and low-dose ritonavir in healthy volunteers. Clin Pharmacol Ther 2002; 71:57-67.
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 57-67
    • Aarnoutse, R.E.1    Grintjes, K.J.2    Telgt, D.S.3
  • 21
    • 0038733440 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of lopinavir associated or not with non-nucleoside reverse transcriptase inhibitors: When and why
    • abstract 7.2. (Washington, DC). Utrecht, The Netherlands: Virology Education BV
    • Solas C, Bosq I, Poizot-Martin I. Therapeutic drug monitoring of lopinavir associated or not with non-nucleoside reverse transcriptase inhibitors: when and why [abstract 7.2]. In: Program and abstracts of the 3rd International Workshop on Clinical Pharmacology of HIV Therapy (Washington, DC). Utrecht, The Netherlands: Virology Education BV, 2002.
    • (2002) Program and Abstracts of the 3rd International Workshop on Clinical Pharmacology of HIV Therapy
    • Solas, C.1    Bosq, I.2    Poizot-Martin, I.3
  • 22
    • 13644262930 scopus 로고    scopus 로고
    • Indinavir TID vs indinavir/ritonavir BID in combination with AZT/3TC for HIV infection in nucleoside pretreated patients: HIV-NAT 005 76-week follow-up
    • abstract 422-W. (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Boyd M, Duncombe C, Ruxrungtham K, et al. Indinavir TID vs indinavir/ritonavir BID in combination with AZT/3TC for HIV infection in nucleoside pretreated patients: HIV-NAT 005 76-week follow-up [abstract 422-W]. In: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • Boyd, M.1    Duncombe, C.2    Ruxrungtham, K.3
  • 23
    • 0037114806 scopus 로고    scopus 로고
    • Open-label study of a twice-daily indinavir 800-mg/ritonavir 100-mg regimen in protease inhibitor-naive HIV-infected adults
    • Young B, Fischl MA, Wilson HM, et al. Open-label study of a twice-daily indinavir 800-mg/ritonavir 100-mg regimen in protease inhibitor-naive HIV-infected adults. J Acquir Immune Defic Syndr 2002; 31:478-82.
    • (2002) J Acquir Immune Defic Syndr , vol.31 , pp. 478-482
    • Young, B.1    Fischl, M.A.2    Wilson, H.M.3
  • 24
    • 0038733439 scopus 로고    scopus 로고
    • Salvage therapy with twice daily indinavir (Crixlvan) 800 mg plus ritonavir (Norvir) 200 mg based regimen in clinical practice
    • abstract 27. (Chicago). London: International Medical Press
    • Grossman H, Luber AD, Butcher D, et al. Salvage therapy with twice daily indinavir (Crixlvan) 800 mg plus ritonavir (Norvir) 200 mg based regimen in clinical practice (abstract 27). In: Program and abstracts of the 3rd International Workshop on Salvage Therapy for HIV Infection (Chicago). London: International Medical Press, 2000.
    • (2000) Program and Abstracts of the 3rd International Workshop on Salvage Therapy for HIV Infection
    • Grossman, H.1    Luber, A.D.2    Butcher, D.3
  • 25
    • 0003318494 scopus 로고    scopus 로고
    • Plasma concentrations of saquinavir (SQV) determine HIV-1 response over a 48-week period
    • abstract 42261. (Geneva). Geneva: Marathon Multimedia
    • Hoetelmans RMW, van Heeswijk RP, Meenhorst PL. Plasma concentrations of saquinavir (SQV) determine HIV-1 response over a 48-week period [abstract 42261]. In: Conference record of the 12th World AIDS Conference (Geneva). Geneva: Marathon Multimedia, 1998.
    • (1998) Conference Record of the 12th World AIDS Conference
    • Hoetelmans, R.M.W.1    Van Heeswijk, R.P.2    Meenhorst, P.L.3
  • 26
    • 0038683438 scopus 로고    scopus 로고
    • Comparative pharmacokinetics and short-term safety of twice daily (BID) fortovase/ritonavir and invirase/ritonavir
    • abstract 432-W. (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Kurowski M, Sternfeld T, Hill A, Moecklinghoff C. Comparative pharmacokinetics and short-term safety of twice daily (BID) fortovase/ritonavir and invirase/ritonavir [abstract 432-W]. In: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • Kurowski, M.1    Sternfeld, T.2    Hill, A.3    Moecklinghoff, C.4
  • 27
    • 0038732493 scopus 로고    scopus 로고
    • Switch of saquinavir 400 mg/ritonavir 400 mg to saquinavir 1000 mg/ritonavir 100 mg during BID four drug antiretroviral therapy
    • abstract 2.1. (Washington, DC). Utrecht, The Netherlands: Virology Education BV
    • O'Brien J. Switch of saquinavir 400 mg/ritonavir 400 mg to saquinavir 1000 mg/ritonavir 100 mg during BID four drug antiretroviral therapy [abstract 2.1]. In: Program and abstracts of the 3rd International Workshop on Clinical Pharmacology of HIV Therapy (Washington, DC). Utrecht, The Netherlands: Virology Education BV, 2002.
    • (2002) Program and Abstracts of the 3rd International Workshop on Clinical Pharmacology of HIV Therapy
    • O'Brien, J.1
  • 28
    • 3142698887 scopus 로고    scopus 로고
    • Final analysis of a randomized trial to evaluate safety and efficacy of indinavir/ritonavir vs saquinavir/ritonavir in adult HIV-1 infection: The MaxCminl trial
    • abstract H-172. (San Diego). Washington, DC: American Society for Microbiology
    • Gerstoft J, Dragsted UB, Cahn P, et al. Final analysis of a randomized trial to evaluate safety and efficacy of indinavir/ritonavir vs saquinavir/ritonavir in adult HIV-1 infection: the MaxCminl trial [abstract H-172]. In: Program and abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy (San Diego). Washington, DC: American Society for Microbiology, 2002.
    • (2002) Program and Abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Gerstoft, J.1    Dragsted, U.B.2    Cahn, P.3
  • 29
    • 0031788930 scopus 로고    scopus 로고
    • ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease
    • Sham HL, Kempf DJ, Molla A, et al. ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease. Antimicrob Agents Chemother 1998;42:3218-24.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 3218-3224
    • Sham, H.L.1    Kempf, D.J.2    Molla, A.3
  • 30
    • 0242455882 scopus 로고    scopus 로고
    • Exploring theoretical mechanisms for lack of resistance to lopinavir/ritonavlr (LPV/r) in antiretroviral (ARV)-naive subjects
    • abstract 436-W. (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Hsu A, Kempf DJ, Granneman R, Sun E. Exploring theoretical mechanisms for lack of resistance to lopinavir/ritonavlr (LPV/r) in antiretroviral (ARV)-naive subjects [abstract 436-W]. In: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • Hsu, A.1    Kempf, D.J.2    Granneman, R.3    Sun, E.4
  • 31
    • 0037182766 scopus 로고    scopus 로고
    • Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection
    • Walmsley S, Bernstein B, King M, et al. Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection. N Engl J Med 2002; 346:2039-46.
    • (2002) N Engl J Med , vol.346 , pp. 2039-2046
    • Walmsley, S.1    Bernstein, B.2    King, M.3
  • 32
    • 17044457875 scopus 로고    scopus 로고
    • ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-Week results
    • Murphy RL, Brun S, Hicks C, et al. ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results. AIDS 2001; 15:F1-9.
    • (2001) AIDS , vol.15
    • Murphy, R.L.1    Brun, S.2    Hicks, C.3
  • 36
    • 0005678653 scopus 로고    scopus 로고
    • Kaletra (lopinavir/ritonavir) and efavirenz: 72-Week safety and efficacy evaluation and phenotypic/genotypic breakpoints in multiple PI-experienced patients
    • abstract 1-1925. (Chicago). Washington, DC: American Society for Microbiology
    • Danner S, Brun S, Sylte J, et al. Kaletra (lopinavir/ritonavir) and efavirenz: 72-week safety and efficacy evaluation and phenotypic/genotypic breakpoints in multiple PI-experienced patients [abstract 1-1925]. In: Program and abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (Chicago). Washington, DC: American Society for Microbiology, 2001.
    • (2001) Program and Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Danner, S.1    Brun, S.2    Sylte, J.3
  • 38
    • 22844434404 scopus 로고    scopus 로고
    • The normalized inhibitory quotient (NIQ) of lopinavir is predictive of viral load response over 48 weeks in a cohort of highly experienced HIV-1 infected individuals
    • abstract 128. (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Castagna A, Danise A, Hasson H, et al. The normalized inhibitory quotient (NIQ) of lopinavir is predictive of viral load response over 48 weeks in a cohort of highly experienced HIV-1 infected individuals [abstract 128]. In: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • Castagna, A.1    Danise, A.2    Hasson, H.3
  • 39
    • 0003351767 scopus 로고    scopus 로고
    • Amprenavir (APV) 600 mg/ritonavir (RTV) 100 mg BID or APV 1200 mg/RTV 200 mg QD given in combination with abacavir (ABC) and lamivudine (3TC) maintains efficacy in ART-naive HIV-1 infected adults over 12 weeks
    • abstract 332. (Chicago). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Wood R, Trepo C, Livrozet JM, et al. Amprenavir (APV) 600 mg/ritonavir (RTV) 100 mg BID or APV 1200 mg/RTV 200 mg QD given in combination with abacavir (ABC) and lamivudine (3TC) maintains efficacy in ART-naive HIV-1 infected adults over 12 weeks [abstract 332]. In: Program and abstracts of the 8th Conference on Retroviruses and Opportunistic Infections (Chicago). Alexandria, VA: Foundation for Retroviruses and Human Health, 2001.
    • (2001) Program and Abstracts of the 8th Conference on Retroviruses and Opportunistic Infections
    • Wood, R.1    Trepo, C.2    Livrozet, J.M.3
  • 40
    • 4644221931 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of amprenavir coadministered with ritonavir in human immunodeficiency virus type 1-infected patients
    • Goujard C, Vincent I, Meynard JL, et al. Steady-state pharmacokinetics of amprenavir coadministered with ritonavir in human immunodeficiency virus type 1-infected patients. Antimicrob Agents Chemother 2003; 47:118-23.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 118-123
    • Goujard, C.1    Vincent, I.2    Meynard, J.L.3
  • 41
    • 0036097178 scopus 로고    scopus 로고
    • Salvage therapy with amprenavir and ritonavir: Prospective study in 17 heavily pretreated patients
    • Arvieux C, Tattevin P, Souala FM, et al. Salvage therapy with amprenavir and ritonavir: prospective study in 17 heavily pretreated patients. HIV Clin Trials 2002; 3:125-32.
    • (2002) HIV Clin Trials , vol.3 , pp. 125-132
    • Arvieux, C.1    Tattevin, P.2    Souala, F.M.3
  • 42
    • 0038394467 scopus 로고    scopus 로고
    • An open-label steady state investigation of the pharmacokinetics (PK) of tipranavir (TPV) and ritonavir (RTV) and their effects on cytochrome P-450 (3A4) activity in normal healthy volunteers
    • abstract 434-W. (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health
    • McCallister S, Sabo J, Galkitz L, Mayers D. An open-label steady state investigation of the pharmacokinetics (PK) of tipranavir (TPV) and ritonavir (RTV) and their effects on cytochrome P-450 (3A4) activity in normal healthy volunteers [abstract 434-W]. In: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • McCallister, S.1    Sabo, J.2    Galkitz, L.3    Mayers, D.4
  • 43
    • 0038732497 scopus 로고    scopus 로고
    • A randomized trial comparing continued indinavir vs. switching to indinavir plus ritonavir in HIV patients having suppressed viral load with indinavir plus two nucleoside analogue reverse transcriptase inhibitors: The best study
    • abstract O-8. (Athens). Athens: Provoli Publicity SA
    • Gerstoft J, Mallolas J, Lundgren J, et al. A randomized trial comparing continued indinavir vs. switching to indinavir plus ritonavir in HIV patients having suppressed viral load with indinavir plus two nucleoside analogue reverse transcriptase inhibitors: the best study [abstract O-8]. In: Program and abstracts of the 8th European Conference on Clinical Aspects and Treatment of HIV Infection (Athens). Athens: Provoli Publicity SA, 2001:19.
    • (2001) Program and Abstracts of the 8th European Conference on Clinical Aspects and Treatment of HIV Infection , pp. 19
    • Gerstoft, J.1    Mallolas, J.2    Lundgren, J.3
  • 44
    • 0037718333 scopus 로고    scopus 로고
    • Combination indinavir/ritonavir in clinical practice
    • abstract WePeB4135. (Durban, South Africa). Rome: International AIDS Society
    • Matthews G, Gazzard B, Nelson M. Combination indinavir/ritonavir in clinical practice [abstract WePeB4135]. In: Program and abstracts of the XIII International AIDS Conference (Durban, South Africa). Rome: International AIDS Society, 2000.
    • (2000) Program and Abstracts of the XIII International AIDS Conference
    • Matthews, G.1    Gazzard, B.2    Nelson, M.3
  • 45
    • 0008433449 scopus 로고    scopus 로고
    • ABT-378/ritonavir (ABT-378/r) suppresses HIV RNA to <400 copies/mL in 84% of PI-experienced patients at 48 weeks
    • abstract 532. (San Francisco). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Deeks S, Brun S, Xu Y, et al. ABT-378/ritonavir (ABT-378/r) suppresses HIV RNA to <400 copies/mL in 84% of PI-experienced patients at 48 weeks [abstract 532]. In: Program and abstracts of the 7th Conference on Retroviruses and Opportunistic Infections (San Francisco). Alexandria, VA: Foundation for Retroviruses and Human Health, 2000.
    • (2000) Program and Abstracts of the 7th Conference on Retroviruses and Opportunistic Infections
    • Deeks, S.1    Brun, S.2    Xu, Y.3
  • 46
    • 33846526960 scopus 로고    scopus 로고
    • The interim analysis of a phase IV randomized, open-label, multicentre trial to evaluate safety and efficacy of indinavir/ritonavir (800/100 mg bid) vs saquinavir/ritonavir (1000/100 mg bid) in adult HIV-1 infection: The maxCmon1 Trial
    • abstract G1008e. (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Castagna A, Dragsted UB, Chave JP, et al. The interim analysis of a phase IV randomized, open-label, multicentre trial to evaluate safety and efficacy of indinavir/ritonavir (800/100 mg bid) vs saquinavir/ritonavir (1000/100 mg bid) in adult HIV-1 infection: the maxCmon1 Trial [abstract G1008e]. in: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • Castagna, A.1    Dragsted, U.B.2    Chave, J.P.3
  • 47
    • 0035455540 scopus 로고    scopus 로고
    • Indinavir crystallization around the loop of Henle: Experimental evidence
    • Dieleman JP, Salahuddin S, Hsu YS, et al. Indinavir crystallization around the loop of Henle: experimental evidence. J Acquir Immune Defic Syndr 2001; 28:9-13.
    • (2001) J Acquir Immune Defic Syndr , vol.28 , pp. 9-13
    • Dieleman, J.P.1    Salahuddin, S.2    Hsu, Y.S.3
  • 48
    • 0033545478 scopus 로고    scopus 로고
    • Urological complaints in relation to indinavir plasma concentrations in HIV-infected patients
    • Dieleman JP, Gyssens IC, van der Ende ME, de Marie S, Burger DM. Urological complaints in relation to indinavir plasma concentrations in HIV-infected patients. AIDS 1999; 13:473-8.
    • (1999) AIDS , vol.13 , pp. 473-478
    • Dieleman, J.P.1    Gyssens, I.C.2    Van Der Ende, M.E.3    De Marie, S.4    Burger, D.M.5
  • 49
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less
    • AIDS Clinical Trials Group 320 Study Team
    • Hammer SM, Squires KE, Hughes MD, et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. N Engl J Med 1997;337:725-33.
    • (1997) N Engl J Med , vol.337 , pp. 725-733
    • Hammer, S.M.1    Squires, K.E.2    Hughes, M.D.3
  • 50
    • 0034604265 scopus 로고    scopus 로고
    • 3-Year suppression of HIV viremia with indinavir, zidovudine, and lamivudine
    • Gulick RM, Mellors JW, Havlir D, et al. 3-Year suppression of HIV viremia with indinavir, zidovudine, and lamivudine. Ann Intern Med 2000; 133:35-9.
    • (2000) Ann Intern Med , vol.133 , pp. 35-39
    • Gulick, R.M.1    Mellors, J.W.2    Havlir, D.3
  • 52
    • 0035280509 scopus 로고    scopus 로고
    • A retrospective, cohort-based survey of patients using twice-daily indinavir plus ritonavir combinations: Pharmacokinetics, safety, and efficacy
    • Burger DM, Hugen PW, Aarnoutse RE, et al. A retrospective, cohort-based survey of patients using twice-daily indinavir plus ritonavir combinations: pharmacokinetics, safety, and efficacy. J Acquir Immune Defic Syndr Hum Retrovirol 2001; 26:218-24.
    • (2001) J Acquir Immune Defic Syndr Hum Retrovirol , vol.26 , pp. 218-224
    • Burger, D.M.1    Hugen, P.W.2    Aarnoutse, R.E.3
  • 53
    • 0003321011 scopus 로고    scopus 로고
    • A randomized study comparing continued indinavir (800mg tid) vs switching to indinavir/ritonavir (800/100mg bid) in HIV patients having achieved viral load suppression with indinavir plus 2 nucleoside analogues: The BID efficacy and safety trial (BEST)
    • abstract WeOrB484. (Durban, South Africa). Rome: International AIDS Society
    • Gatell JM, Lange J, Arnaiz JA. A randomized study comparing continued indinavir (800mg tid) vs switching to indinavir/ritonavir (800/100mg bid) in HIV patients having achieved viral load suppression with indinavir plus 2 nucleoside analogues: the BID efficacy and safety trial (BEST) [abstract WeOrB484]. In: Program and abstracts of the XIII International AIDS Conference (Durban, South Africa). Rome: International AIDS Society, 2000.
    • (2000) Program and Abstracts of the XIII International AIDS Conference
    • Gatell, J.M.1    Lange, J.2    Arnaiz, J.A.3
  • 54
    • 0038394470 scopus 로고    scopus 로고
    • A randomised, open label trial of indinavir/ritonavir vs indinavir in combination with AZT/3TC for the treatment of HIV infection in nucleoside experienced patients: Results of 112 weeks follow-up
    • abstract G30e. (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Boyd M, Duncombe C, Ruxrungthan K, et al. A randomised, open label trial of indinavir/ritonavir vs indinavir in combination with AZT/3TC for the treatment of HIV infection in nucleoside experienced patients: results of 112 weeks follow-up [abstract G30e]. In: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • Boyd, M.1    Duncombe, C.2    Ruxrungthan, K.3
  • 55
    • 0000692170 scopus 로고    scopus 로고
    • Indinavir/ritonavir vs indinavir in combination with AZT/3TC for the treatment of HIV infection in nucleoside experienced patients: A randomized, open label trial
    • abstract 335. (Chicago). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Boyd M, Duncombe C, Newell M, et al. Indinavir/ritonavir vs indinavir in combination with AZT/3TC for the treatment of HIV infection in nucleoside experienced patients: a randomized, open label trial [abstract 335]. In: Program and abstracts of the 8th Conference on Retroviruses and Opportunistic Infections (Chicago). Alexandria, VA: Foundation for Retroviruses and Human Health, 2001.
    • (2001) Program and Abstracts of the 8th Conference on Retroviruses and Opportunistic Infections
    • Boyd, M.1    Duncombe, C.2    Newell, M.3
  • 56
    • 0036857180 scopus 로고    scopus 로고
    • Experience of a combination including indinavir 400 mg plus ritonavir 200 mg twice daily in HIV-infected patients: Pharmacokinetic data
    • Solas C, Petit N, Orticoni M, Durand A, Gastaut JA, Lacarelle B. Experience of a combination including indinavir 400 mg plus ritonavir 200 mg twice daily in HIV-infected patients: pharmacokinetic data. Pathol Biol (Paris) 2002;50:565-7.
    • (2002) Pathol Biol (Paris) , vol.50 , pp. 565-567
    • Solas, C.1    Petit, N.2    Orticoni, M.3    Durand, A.4    Gastaut, J.A.5    Lacarelle, B.6
  • 57
    • 0038057055 scopus 로고    scopus 로고
    • Lipid profiles in patients on ritonavir/indinavir containing salvage regimens
    • abstract 24
    • Youle M, Mocroft A, Johnson M. Lipid profiles in patients on ritonavir/indinavir containing salvage regimens [abstract 24]. Antivir Ther 1999; 4(Suppl 2):22.
    • (1999) Antivir Ther , vol.4 , Issue.SUPPL. 2 , pp. 22
    • Youle, M.1    Mocroft, A.2    Johnson, M.3
  • 58
    • 3042702232 scopus 로고    scopus 로고
    • Final analysis of a randomised trial to evaluate safety and efficacy of indinavir/ritonavir versus saquinavir/ritonavir in adult HIV-1 infection: The MaxCmin1 trial
    • abstract P29. (Glasgow, UK). London: Lippincott Williams & Wilkins
    • Gerstoff J, Dragsted UB, Cahn P, et al. Final analysis of a randomised trial to evaluate safety and efficacy of indinavir/ritonavir versus saquinavir/ritonavir in adult HIV-1 infection: the MaxCmin1 trial [abstract P29]. In: Program and abstracts of the 6th International Congress on Drug Therapy in HIV Infection (Glasgow, UK). London: Lippincott Williams & Wilkins, 2002.
    • (2002) Program and Abstracts of the 6th International Congress on Drug Therapy in HIV Infection
    • Gerstoff, J.1    Dragsted, U.B.2    Cahn, P.3
  • 59
    • 0034606721 scopus 로고    scopus 로고
    • Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection
    • Sulkowski MS, Thomas DL, Chaisson RE, Moore RD. Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection. JAMA 2000; 283:74-80.
    • (2000) JAMA , vol.283 , pp. 74-80
    • Sulkowski, M.S.1    Thomas, D.L.2    Chaisson, R.E.3    Moore, R.D.4
  • 60
    • 6844240219 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease
    • The Advanced HIV Disease Ritonavir Study Group
    • Cameron DW, Heath-Chiozzi M, Danner S, et al. Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. The Advanced HIV Disease Ritonavir Study Group. Lancet 1998; 351:543-9.
    • (1998) Lancet , vol.351 , pp. 543-549
    • Cameron, D.W.1    Heath-Chiozzi, M.2    Danner, S.3
  • 61
    • 0003312485 scopus 로고    scopus 로고
    • Antiretroviral safety and durability of ritonavir-saquinavir in protease inhibitor-naive patients in year two of follow-up
    • abstract 388. (Chicago). Alexandria, VA: Foundation for Retroviruses and Human Health
    • Cameron DW, Japour A, Farthing C, et al. Antiretroviral safety and durability of ritonavir-saquinavir in protease inhibitor-naive patients in year two of follow-up [abstract 388]. In: Program and abstracts of the 5th Conference on Retroviruses and Opportunistic Infections (Chicago). Alexandria, VA: Foundation for Retroviruses and Human Health, 1998.
    • (1998) Program and Abstracts of the 5th Conference on Retroviruses and Opportunistic Infections
    • Cameron, D.W.1    Japour, A.2    Farthing, C.3
  • 62
    • 0032504922 scopus 로고    scopus 로고
    • Acute hepatitis in HIV-infected patients during ritonavir treatment
    • Arribas JR, Ibanez C, Ruiz-Antoran B, et al. Acute hepatitis in HIV-infected patients during ritonavir treatment. AIDS 1998; 12:1722-4.
    • (1998) AIDS , vol.12 , pp. 1722-1724
    • Arribas, J.R.1    Ibanez, C.2    Ruiz-Antoran, B.3
  • 63
    • 0036569989 scopus 로고    scopus 로고
    • Hepatotoxicity associated with antiretroviral therapy containing dual versus single protease inhibitors in individuals coinfected with hepatitis C virus and human immunodeficiency virus
    • Cooper CL, Parbhakar MA, Angel JB. Hepatotoxicity associated with antiretroviral therapy containing dual versus single protease inhibitors in individuals coinfected with hepatitis C virus and human immunodeficiency virus. Clin Infect Dis 2002;34:1259-63.
    • (2002) Clin Infect Dis , vol.34 , pp. 1259-1263
    • Cooper, C.L.1    Parbhakar, M.A.2    Angel, J.B.3
  • 64
    • 0037671721 scopus 로고    scopus 로고
    • Direct study: A multicenter, open-label, 24-wk pilot study with a 24-wk extension to evaluate the safety, tolerability and efficacy of indinavir-ritonavir 800/100 bid in combination with d4T plus 3TC in HIV-infected individuals
    • abstract I-1923. (Chicago). Washington, DC: American Society for Microbiology
    • Fischl MA, Young B, Watkins M, et al. Direct study: a multicenter, open-label, 24-wk pilot study with a 24-wk extension to evaluate the safety, tolerability and efficacy of indinavir-ritonavir 800/100 bid in combination with d4T plus 3TC in HIV-infected individuals [abstract I-1923]. In: Program and abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (Chicago). Washington, DC: American Society for Microbiology, 2001.
    • (2001) Program and Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Fischl, M.A.1    Young, B.2    Watkins, M.3
  • 65
    • 0038733436 scopus 로고    scopus 로고
    • Protocol 107: A multicenter, open-label, 24-week study to evaluate the efficacy and safety of indinavir sulfate 800 mg and ritonavir 200 mg BID plus 2 NRTIs bid in HIV-1 infected individuals who require early treatment intervention
    • abstract 1-1922. (Chicago). Washington, DC: American Society for Microbiology
    • Katner H, Dejesus E, Paar D, et al. Protocol 107: a multicenter, open-label, 24-week study to evaluate the efficacy and safety of indinavir sulfate 800 mg and ritonavir 200 mg BID plus 2 NRTIs bid in HIV-1 infected individuals who require early treatment intervention [abstract 1-1922]. In: Program and abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (Chicago). Washington, DC: American Society for Microbiology, 2001.
    • (2001) Program and Abstracts of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Katner, H.1    Dejesus, E.2    Paar, D.3
  • 66
    • 0006214620 scopus 로고    scopus 로고
    • Multiple dose pharmacokinetics and tolerability of once-daily nelfinavir and ritonavir combinations in healthy volunteers
    • abstract 1.3. (Noordwijk, The Netherlands). Utrecht, The Netherlands: Virology Education BV
    • Aarnoute R, Burger DM, van Oosterhout J. Multiple dose pharmacokinetics and tolerability of once-daily nelfinavir and ritonavir combinations in healthy volunteers [abstract 1.3]. In: Program and abstracts of the 2nd International Workshop on Clinical Pharmacology of HIV Therapy (Noordwijk, The Netherlands). Utrecht, The Netherlands: Virology Education BV, 2001.
    • (2001) Program and Abstracts of the 2nd International Workshop on Clinical Pharmacology of HIV Therapy
    • Aarnoute, R.1    Burger, D.M.2    Van Oosterhout, J.3
  • 68
    • 0036235089 scopus 로고    scopus 로고
    • Simplifying protease inhibitor therapy with once-daily dosing of saquinavir soft-gelatin capsules/ritonavir (1600/100 mg): HIVNAT 001.3 study
    • Cardiello PG, van Heeswijk RP, Hassink EA, et al. Simplifying protease inhibitor therapy with once-daily dosing of saquinavir soft-gelatin capsules/ritonavir (1600/100 mg): HIVNAT 001.3 study. J Acquir Immune Defic Syndr 2002;29:464-70.
    • (2002) J Acquir Immune Defic Syndr , vol.29 , pp. 464-470
    • Cardiello, P.G.1    Van Heeswijk, R.P.2    Hassink, E.A.3
  • 69
    • 0033730346 scopus 로고    scopus 로고
    • Once-daily indinavir plus ritonavir: Preliminary results of the PIPO study
    • Burger DM, Hugen PW, van der Ende ME, et al. Once-daily indinavir plus ritonavir: preliminary results of the PIPO study. AIDS 2000; 14:2621-3.
    • (2000) AIDS , vol.14 , pp. 2621-2623
    • Burger, D.M.1    Hugen, P.W.2    Van Der Ende, M.E.3
  • 73
    • 0006179308 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of amprenavir and ritonavir following multiple-dose, co-administration to healthy volunteers
    • Sadler BM, Piliero PJ, Preston SL, Lloyd PP, Lou Y, Stein DS. Pharmacokinetics and safety of amprenavir and ritonavir following multiple-dose, co-administration to healthy volunteers. AIDS 2001; 15:1009-18.
    • (2001) AIDS , vol.15 , pp. 1009-1018
    • Sadler, B.M.1    Piliero, P.J.2    Preston, S.L.3    Lloyd, P.P.4    Lou, Y.5    Stein, D.S.6
  • 76
    • 0008495319 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of once daily saquinavir soft gel capsules/ritonavir in HiV-infected antiretroviral naive patients
    • abstract 3.14. (Noordwijk, The Netherlands). Utrecht, The Netherlands: Virology Education BV
    • Acosta EP, Saag MS, Montaner JSG. Pharmacokinetics and safety of once daily saquinavir soft gel capsules/ritonavir in HiV-infected antiretroviral naive patients [abstract 3.14]. In: Program and abstracts of the 2nd International Workshop on Clinical Pharmacology of HIV Therapy (Noordwijk, The Netherlands). Utrecht, The Netherlands: Virology Education BV, 2001.
    • (2001) Program and Abstracts of the 2nd International Workshop on Clinical Pharmacology of HIV Therapy
    • Acosta, E.P.1    Saag, M.S.2    Montaner, J.S.G.3
  • 77
    • 0035029205 scopus 로고    scopus 로고
    • The role of therapeutic drug monitoring in treatment of HIV infection
    • Back DJ, Khoo SH, Gibbons SE, Merry C. The role of therapeutic drug monitoring in treatment of HIV infection. Br J Clin Pharmacol 2001; 51:301-8.
    • (2001) Br J Clin Pharmacol , vol.51 , pp. 301-308
    • Back, D.J.1    Khoo, S.H.2    Gibbons, S.E.3    Merry, C.4
  • 80
    • 33646808201 scopus 로고    scopus 로고
    • Saquinavir plasma and intracellular concentrations in a once daily dosing combinations Fortovase/low-dose ritonavir in a prospective study (IMEA 015) in HIV-infected patients
    • abstract 3.16. (Noordwijk, The Netherlands). Utrecht, The Netherlands: Virology Education BV
    • Peytavin G, Landman R, Lamotte C. Saquinavir plasma and intracellular concentrations in a once daily dosing combinations Fortovase/low-dose ritonavir in a prospective study (IMEA 015) in HIV-infected patients [abstract 3.16]. In: Program and abstracts of the 2nd International Workshop on Clinical Pharmacology of HIV Therapy (Noordwijk, The Netherlands). Utrecht, The Netherlands: Virology Education BV, 2001.
    • (2001) Program and Abstracts of the 2nd International Workshop on Clinical Pharmacology of HIV Therapy
    • Peytavin, G.1    Landman, R.2    Lamotte, C.3
  • 81
    • 0036864550 scopus 로고    scopus 로고
    • Intracellular concentration of protease inhibitors in HIV-1-infected patients: Correlation with MDR-1 gene expression and low dose of ritonavir
    • Chaillou S, Durant J, Garraffo R, et al. Intracellular concentration of protease inhibitors in HIV-1-infected patients: correlation with MDR-1 gene expression and low dose of ritonavir. HIV Clin Trials 2002; 3:493-501.
    • (2002) HIV Clin Trials , vol.3 , pp. 493-501
    • Chaillou, S.1    Durant, J.2    Garraffo, R.3
  • 82
    • 0037718335 scopus 로고    scopus 로고
    • The efficacy, safety, and immunological changes of qd saquinavir-soft gel capsule 1600 mg/ritonavir 100 mg plus dual nucleosides in patients who had an undetectable viral load after 3 years of treatment
    • abstract 549-T. (Seattle) Alexandria, VA: Foundation for Retroviruses and Human Health
    • Cardiello PG, Srasuebkul P, Hassink EA, et al. The efficacy, safety, and immunological changes of qd saquinavir-soft gel capsule 1600 mg/ritonavir 100 mg plus dual nucleosides in patients who had an undetectable viral load after 3 years of treatment [abstract 549-T]. In: Program and abstracts of the 9th Conference on Retroviruses and Opportunistic Infections (Seattle). Alexandria, VA: Foundation for Retroviruses and Human Health, 2002.
    • (2002) Program and Abstracts of the 9th Conference on Retroviruses and Opportunistic Infections
    • Cardiello, P.G.1    Srasuebkul, P.2    Hassink, E.A.3
  • 84
    • 0032839921 scopus 로고    scopus 로고
    • Efficacy of a five-drug combination including ritonavir, saqulnavir and efavirenz in patients who failed on a conventional triple-drug regimen: Phenotypic resistance to protease inhibitors predicts outcome of therapy
    • Piketty C, Race E, Castiel P, et al. Efficacy of a five-drug combination including ritonavir, saqulnavir and efavirenz in patients who failed on a conventional triple-drug regimen: phenotypic resistance to protease inhibitors predicts outcome of therapy. AIDS 1999; 13:F71-7.
    • (1999) AIDS , vol.13
    • Piketty, C.1    Race, E.2    Castiel, P.3
  • 86
    • 0004843529 scopus 로고    scopus 로고
    • Efficacy of indinavir (IDV)/ritonavir (RTV)-based regimens (IRBR) among patients with prior protease inhibitor failure
    • Campo R, Suarez G, Miller N. Efficacy of indinavir (IDV)/ritonavir (RTV)-based regimens (IRBR) among patients with prior protease inhibitor failure [abstract]. Antivir Ther 2000; 5(Suppl 2):27.
    • (2000) Antivir Ther , vol.5 , Issue.SUPPL. 2 , pp. 27
    • Campo, R.1    Suarez, G.2    Miller, N.3
  • 87
    • 0031849665 scopus 로고    scopus 로고
    • In vitro selection and characterization of human immunodeficiency virus type 1 variants with increased resistance to ABT-378, a novel protease inhibitor
    • Carrillo A, Stewart KD, Sham HL, et al. In vitro selection and characterization of human immunodeficiency virus type 1 variants with increased resistance to ABT-378, a novel protease inhibitor. J Virol 1998; 72:7532-41.
    • (1998) J Virol , vol.72 , pp. 7532-7541
    • Carrillo, A.1    Stewart, K.D.2    Sham, H.L.3
  • 88


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