Selective inhibition of P-glycoprotein expression in multidrug-resistant tumor cells by a designed transcriptional regulator

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 3, 2002, Pages 963-971

  Xu, Dong ^a   Ye, Dongjiu ^a   Fisher, Michael ^a   Juliano, R L ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PONASTERONE A; REPRESSOR PROTEIN; RHODAMINE 123; TRANSCRIPTION REGULATOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCHEMISTRY; BREAST CARCINOMA; CANCER GENETICS; CONTROLLED STUDY; DNA MICROARRAY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SELECTIVITY; DRUG TARGETING; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; INHIBITION KINETICS; MDR1 GENE; MOLECULAR CLONING; MULTIDRUG RESISTANCE; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRESSOR GENE; TRANSCRIPTION REGULATION; TUMOR CELL CULTURE;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; BLOTTING, NORTHERN; BLOTTING, WESTERN; DOXORUBICIN; FLOW CYTOMETRY; FLUORESCENT DYES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MDR; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; P-GLYCOPROTEINS; PLASMIDS; REPRESSOR PROTEINS; RHODAMINE 123; RNA, NEOPLASM; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036721426     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.033639     Document Type: Article

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