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Volumn 45, Issue 5, 2006, Pages 308-316

Oxidative and nitrosative stress in pediatric pulmonary hypertension: Roles of endothelin-1 and nitric oxide

Author keywords

Cell signaling; Gene expression; Nitrosylation; Pulmonary hypertension; Reactive oxygen species

Indexed keywords

CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; HYDROGEN PEROXIDE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

EID: 33751086463     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2006.08.005     Document Type: Article
Times cited : (37)

References (125)
  • 1
    • 0025963441 scopus 로고
    • Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia
    • Adnot S., Raffestin B., Eddahibi S., Braquet P., and Chabrier P.-E. Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J. Clin. Invest. 87 (1991) 155-162
    • (1991) J. Clin. Invest. , vol.87 , pp. 155-162
    • Adnot, S.1    Raffestin, B.2    Eddahibi, S.3    Braquet, P.4    Chabrier, P.-E.5
  • 2
    • 0025605345 scopus 로고
    • Cloning and expression of a cDNA encoding an endothelin receptor
    • Arai H., Hori S., Aramori I., Ohkubo H., and Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 348 (1990) 730-732
    • (1990) Nature , vol.348 , pp. 730-732
    • Arai, H.1    Hori, S.2    Aramori, I.3    Ohkubo, H.4    Nakanishi, S.5
  • 4
    • 0030559686 scopus 로고    scopus 로고
    • Rebound pulmonary hypertension after inhalation of nitric oxide
    • Atz A., Adatia I., and Wessel D. Rebound pulmonary hypertension after inhalation of nitric oxide. Ann. Thorac. Surg. 62 (1996) 1759-1764
    • (1996) Ann. Thorac. Surg. , vol.62 , pp. 1759-1764
    • Atz, A.1    Adatia, I.2    Wessel, D.3
  • 5
    • 0028802726 scopus 로고
    • Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms
    • Beavo J.A. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol. Rev. 75 (1995) 725-748
    • (1995) Physiol. Rev. , vol.75 , pp. 725-748
    • Beavo, J.A.1
  • 6
    • 0031755388 scopus 로고    scopus 로고
    • Coordinated regulation of genes of the nitric oxide and endothelin pathways during the development of pulmonary hypertension in fetal lambs
    • Black S.M., Johengen M.J., and Soifer S.J. Coordinated regulation of genes of the nitric oxide and endothelin pathways during the development of pulmonary hypertension in fetal lambs. Pediatr. Res. 44 (1998) 821-830
    • (1998) Pediatr. Res. , vol.44 , pp. 821-830
    • Black, S.M.1    Johengen, M.J.2    Soifer, S.J.3
  • 8
    • 0025100874 scopus 로고
    • Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide
    • Boulanger C., and Luscher T.F. Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide. J. Clin. Invest. 85 (1990) 587-590
    • (1990) J. Clin. Invest. , vol.85 , pp. 587-590
    • Boulanger, C.1    Luscher, T.F.2
  • 9
    • 0025149307 scopus 로고
    • Circulatory effects of endothelin in newborn piglets
    • Bradley L.M., Czaja J.F., and Goldstein R.E. Circulatory effects of endothelin in newborn piglets. Am. J. Physiol. 259 (1990) H1613-H1617
    • (1990) Am. J. Physiol. , vol.259
    • Bradley, L.M.1    Czaja, J.F.2    Goldstein, R.E.3
  • 10
    • 0024263973 scopus 로고
    • Augmentation of hypoxic pulmonary vasoconstriction in the isolated perfused rat lung by in vitro antagonists of endothelium-dependent relaxation
    • Brashers V.L., Peach M.J., and Rose Jr. C.E. Augmentation of hypoxic pulmonary vasoconstriction in the isolated perfused rat lung by in vitro antagonists of endothelium-dependent relaxation. J. Clin. Invest. 82 (1988) 1495-1502
    • (1988) J. Clin. Invest. , vol.82 , pp. 1495-1502
    • Brashers, V.L.1    Peach, M.J.2    Rose Jr., C.E.3
  • 11
    • 0036932088 scopus 로고    scopus 로고
    • The overexpression of copper-zinc superoxide dismutase protects NOS III from nitric oxide-mediated inhibition
    • Brennan L.A., Wedgwood S., Bekker J.M., and Black S.M. The overexpression of copper-zinc superoxide dismutase protects NOS III from nitric oxide-mediated inhibition. DNA Cell Biol. 21 (2002) 827-838
    • (2002) DNA Cell Biol. , vol.21 , pp. 827-838
    • Brennan, L.A.1    Wedgwood, S.2    Bekker, J.M.3    Black, S.M.4
  • 12
    • 0036878975 scopus 로고    scopus 로고
    • The overexpression catalase reduces NO-mediated inhibition of endothelial NO synthase
    • Brennan L.A., Wedgwood S., and Black S.M. The overexpression catalase reduces NO-mediated inhibition of endothelial NO synthase. IUBMB Life 54 (2002) 261-265
    • (2002) IUBMB Life , vol.54 , pp. 261-265
    • Brennan, L.A.1    Wedgwood, S.2    Black, S.M.3
  • 13
  • 16
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular disease: the role of oxidant stress
    • Cai H., and Harrison D. Endothelial dysfunction in cardiovascular disease: the role of oxidant stress. Circ. Res. 87 (2000) 840-844
    • (2000) Circ. Res. , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.2
  • 17
    • 0042379916 scopus 로고    scopus 로고
    • The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases
    • Cai H., Griendling K.K., and Harrison D.G. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol. Sci. 24 (2003) 471-478
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 471-478
    • Cai, H.1    Griendling, K.K.2    Harrison, D.G.3
  • 18
    • 0026089590 scopus 로고
    • Tone-dependent responses to endothelin in isolated perfused fetal sheep pulmonary circulation in situ
    • Cassin S., Kristova V., Davis T., Kadowitz P., and Gause G. Tone-dependent responses to endothelin in isolated perfused fetal sheep pulmonary circulation in situ. J. Appl. Physiol. 70 (1991) 1228-1234
    • (1991) J. Appl. Physiol. , vol.70 , pp. 1228-1234
    • Cassin, S.1    Kristova, V.2    Davis, T.3    Kadowitz, P.4    Gause, G.5
  • 19
    • 0027476062 scopus 로고
    • Impairment of endothelium-dependent pulmonary artery relaxation in children with congenital heart disease and abnormal pulmonary hemodynamics
    • Celermajer D.S., Cullen S., and Deanfield J.E. Impairment of endothelium-dependent pulmonary artery relaxation in children with congenital heart disease and abnormal pulmonary hemodynamics. Circulation 87 (1993) 440-446
    • (1993) Circulation , vol.87 , pp. 440-446
    • Celermajer, D.S.1    Cullen, S.2    Deanfield, J.E.3
  • 20
    • 0034771241 scopus 로고    scopus 로고
    • Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells
    • Cheng T.H., Shih N.L., Chen S.Y., Loh S.H., Cheng P.Y., Tsai C.S., Liu S.H., Wang D.L., and Chen J.J. Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells. J. Mol. Cell. Cardiol. 33 (2001) 1805-1814
    • (2001) J. Mol. Cell. Cardiol. , vol.33 , pp. 1805-1814
    • Cheng, T.H.1    Shih, N.L.2    Chen, S.Y.3    Loh, S.H.4    Cheng, P.Y.5    Tsai, C.S.6    Liu, S.H.7    Wang, D.L.8    Chen, J.J.9
  • 22
    • 0026662501 scopus 로고
    • Oxidation-reduction-sensitive binding of lung protein to rat catalase mRNA
    • Clerch L.B., and Massaro D. Oxidation-reduction-sensitive binding of lung protein to rat catalase mRNA. J. Biol. Chem. 267 (1992) 2853-2855
    • (1992) J. Biol. Chem. , vol.267 , pp. 2853-2855
    • Clerch, L.B.1    Massaro, D.2
  • 23
    • 0026808952 scopus 로고
    • Rat lung antioxidant enzymes: differences in perinatal gene expression and regulation
    • Clerch L.B., and Massaro D. Rat lung antioxidant enzymes: differences in perinatal gene expression and regulation. Am. J. Physiol. 263 (1992) L466-L470
    • (1992) Am. J. Physiol. , vol.263
    • Clerch, L.B.1    Massaro, D.2
  • 24
    • 0036479214 scopus 로고    scopus 로고
    • Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR
    • Colavitti R., Pani G., Bedogni B., Anzevino R., Borrello S., Waltenberger J., and Galeotti T. Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR. J. Biol. Chem. 277 (2002) 3101-3108
    • (2002) J. Biol. Chem. , vol.277 , pp. 3101-3108
    • Colavitti, R.1    Pani, G.2    Bedogni, B.3    Anzevino, R.4    Borrello, S.5    Waltenberger, J.6    Galeotti, T.7
  • 25
    • 0031460678 scopus 로고    scopus 로고
    • Life-threatening effects of discontinuing inhaled nitric oxide in children
    • Cueto E., Lopez-Herce J., Sanchez A., and Carrillo A. Life-threatening effects of discontinuing inhaled nitric oxide in children. Acta Pediatr. 86 (1997) 1337-1339
    • (1997) Acta Pediatr. , vol.86 , pp. 1337-1339
    • Cueto, E.1    Lopez-Herce, J.2    Sanchez, A.3    Carrillo, A.4
  • 26
    • 0030690053 scopus 로고    scopus 로고
    • A randomized, controlled study of the 1-hour and 24-hour effects of inhaled nitric oxide therapy in children with acute hypoxemic respiratory failure
    • Day R.W., Allen E.M., and Witte M.K. A randomized, controlled study of the 1-hour and 24-hour effects of inhaled nitric oxide therapy in children with acute hypoxemic respiratory failure. Chest 112 (1997) 1324-1331
    • (1997) Chest , vol.112 , pp. 1324-1331
    • Day, R.W.1    Allen, E.M.2    Witte, M.K.3
  • 27
    • 0031975630 scopus 로고    scopus 로고
    • Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Inhaled Nitric Oxide in ARDS Study Group
    • Dellinger R.P., Zimmerman J.L., Taylor R.W., Straube R.C., Hauser D.L., Criner G.J., Davis Jr. K., Hyers T.M., and Papadakos P. Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Inhaled Nitric Oxide in ARDS Study Group. Crit. Care Med. 26 (1998) 15-23
    • (1998) Crit. Care Med. , vol.26 , pp. 15-23
    • Dellinger, R.P.1    Zimmerman, J.L.2    Taylor, R.W.3    Straube, R.C.4    Hauser, D.L.5    Criner, G.J.6    Davis Jr., K.7    Hyers, T.M.8    Papadakos, P.9
  • 30
    • 0033952940 scopus 로고    scopus 로고
    • Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide
    • Drummond G., Cai H., Davis M., Ramasamy S., and Harrison D. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide. Circ. Res. 86 (2000) 347-354
    • (2000) Circ. Res. , vol.86 , pp. 347-354
    • Drummond, G.1    Cai, H.2    Davis, M.3    Ramasamy, S.4    Harrison, D.5
  • 31
    • 20444409884 scopus 로고    scopus 로고
    • Receptor-regulated dynamic S-nitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells
    • Erwin P.A., Lin A.J., Golan D.E., and Michel T. Receptor-regulated dynamic S-nitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells. J. Biol. Chem. 280 (2005) 19888-19894
    • (2005) J. Biol. Chem. , vol.280 , pp. 19888-19894
    • Erwin, P.A.1    Lin, A.J.2    Golan, D.E.3    Michel, T.4
  • 33
    • 0028935785 scopus 로고
    • Regulation of pulmonary vascular tone in the perinatal period
    • Fineman J.R., Soifer S.J., and Heymann M.A. Regulation of pulmonary vascular tone in the perinatal period. Annu. Rev. Physiol. 57 (1995) 115-134
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 115-134
    • Fineman, J.R.1    Soifer, S.J.2    Heymann, M.A.3
  • 34
    • 0021289034 scopus 로고
    • 2-rich environment: the antioxidant enzymes in the developing rabbit lung
    • 2-rich environment: the antioxidant enzymes in the developing rabbit lung. Pediatr. Res. 18 (1984) 240-244
    • (1984) Pediatr. Res. , vol.18 , pp. 240-244
    • Frank, L.1    Groseclose, E.E.2
  • 36
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg U.C., and Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J. Clin. Invest. 83 (1989) 1774-1777
    • (1989) J. Clin. Invest. , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 37
    • 0029055964 scopus 로고
    • Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • Giaid A., and Saleh D. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. 333 (1995) 214-221
    • (1995) N. Engl. J. Med. , vol.333 , pp. 214-221
    • Giaid, A.1    Saleh, D.2
  • 39
    • 0142055950 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part I. Basic mechanisms and in vivo monitoring of ROS
    • Griendling K.K., and FitzGerald G.A. Oxidative stress and cardiovascular injury: Part I. Basic mechanisms and in vivo monitoring of ROS. Circulation 108 (2003) 1912-1916
    • (2003) Circulation , vol.108 , pp. 1912-1916
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 40
    • 0033781454 scopus 로고    scopus 로고
    • Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology
    • Griendling K.K., Sorescu D., Lassegue B., and Ushio-Fukai M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler. Thromb. Vasc. Biol. 20 (2000) 2175-2183
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 2175-2183
    • Griendling, K.K.1    Sorescu, D.2    Lassegue, B.3    Ushio-Fukai, M.4
  • 42
    • 0028402896 scopus 로고
    • Endothelin-stimulated monocyte supernatants enhance neutrophil superoxide production
    • Huribal M., Kumar R., Cunningham M., Sumpio B., and McMillen M. Endothelin-stimulated monocyte supernatants enhance neutrophil superoxide production. Shock 1 (1994) 184-187
    • (1994) Shock , vol.1 , pp. 184-187
    • Huribal, M.1    Kumar, R.2    Cunningham, M.3    Sumpio, B.4    McMillen, M.5
  • 43
    • 0022461711 scopus 로고
    • Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin and arachidonic acid
    • Ignarro L.J., Harbison R.G., Wood K.S., and Kadowitz P.J. Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin and arachidonic acid. J. Pharmacol. Exp. Ther. 237 (1986) 893-900
    • (1986) J. Pharmacol. Exp. Ther. , vol.237 , pp. 893-900
    • Ignarro, L.J.1    Harbison, R.G.2    Wood, K.S.3    Kadowitz, P.J.4
  • 44
    • 0026566370 scopus 로고
    • Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells
    • Imai T., Hirata Y., Emori T., Yanagisawa M., Masaki T., and Marumo F. Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells. Hypertension 19 (1992) 753-757
    • (1992) Hypertension , vol.19 , pp. 753-757
    • Imai, T.1    Hirata, Y.2    Emori, T.3    Yanagisawa, M.4    Masaki, T.5    Marumo, F.6
  • 45
    • 0034622996 scopus 로고    scopus 로고
    • Chronic treatment with probucol effectively inhibits progression of pulmonary hypertension in rats
    • Irukayama-Tomobe Y., Sakai S., and Miyauchi T. Chronic treatment with probucol effectively inhibits progression of pulmonary hypertension in rats. Life Sci. 67 (2000) 2017-2023
    • (2000) Life Sci. , vol.67 , pp. 2017-2023
    • Irukayama-Tomobe, Y.1    Sakai, S.2    Miyauchi, T.3
  • 46
    • 23444436906 scopus 로고
    • Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation
    • Ivy D.D., Kinsella J.P., and Abman S.H. Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation. J. Clin. Invest. 93 (1994) 2141-2148
    • (1994) J. Clin. Invest. , vol.93 , pp. 2141-2148
    • Ivy, D.D.1    Kinsella, J.P.2    Abman, S.H.3
  • 48
    • 0022919381 scopus 로고
    • Malformations induced in cultured rat embryos by enzymically generated active oxygen species
    • Jenkinson P.C., Anderson D., and Gangolli S.D. Malformations induced in cultured rat embryos by enzymically generated active oxygen species. Teratog., Carcinog., Mutagen. 6 (1986) 547-554
    • (1986) Teratog., Carcinog., Mutagen. , vol.6 , pp. 547-554
    • Jenkinson, P.C.1    Anderson, D.2    Gangolli, S.D.3
  • 50
    • 0031015923 scopus 로고    scopus 로고
    • Endothelin production links superoxide generation to altered opioid-induced pial artery vasodilation after brain injury in pigs
    • Kasemsri T., and Armstead W. Endothelin production links superoxide generation to altered opioid-induced pial artery vasodilation after brain injury in pigs. Stroke 28 (1997) 190-196
    • (1997) Stroke , vol.28 , pp. 190-196
    • Kasemsri, T.1    Armstead, W.2
  • 51
    • 0029942652 scopus 로고    scopus 로고
    • Superoxide anion and endothelial regulation of arterial tone
    • Katusic Z.S. Superoxide anion and endothelial regulation of arterial tone. Free Radic. Biol. Med. 20 (1996) 443-448
    • (1996) Free Radic. Biol. Med. , vol.20 , pp. 443-448
    • Katusic, Z.S.1
  • 54
    • 0030020062 scopus 로고    scopus 로고
    • Endothelin-1 has a priming effect on production of superoxide anion by alveolar macrophages: its possible correlation with bronchopulmonary dysplasia
    • Kojima T., Hattori K., Hirata Y., Aoki T., Sasai-Takedatsu M., Kino M., and Kobayashi Y. Endothelin-1 has a priming effect on production of superoxide anion by alveolar macrophages: its possible correlation with bronchopulmonary dysplasia. Pediatr. Res. 39 (1996) 112-116
    • (1996) Pediatr. Res. , vol.39 , pp. 112-116
    • Kojima, T.1    Hattori, K.2    Hirata, Y.3    Aoki, T.4    Sasai-Takedatsu, M.5    Kino, M.6    Kobayashi, Y.7
  • 55
    • 0027260899 scopus 로고
    • Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia
    • Kourembanas S., McQuillan L.P., Leung G.K., and Faller D.V. Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia. J. Clin. Invest. 92 (1993) 99-104
    • (1993) J. Clin. Invest. , vol.92 , pp. 99-104
    • Kourembanas, S.1    McQuillan, L.P.2    Leung, G.K.3    Faller, D.V.4
  • 56
    • 0027403186 scopus 로고
    • Shear stress regulates endothelin-1 release via protein kinase C and cGMP in cultured endothelial cells
    • Kuchan M.J., and Frangos J.A. Shear stress regulates endothelin-1 release via protein kinase C and cGMP in cultured endothelial cells. Am. J. Physiol. 264 (1993) H150-H156
    • (1993) Am. J. Physiol. , vol.264
    • Kuchan, M.J.1    Frangos, J.A.2
  • 58
    • 0028997449 scopus 로고
    • Endothelin-1 and the regulation of vascular tone
    • La M., and Reid J.J. Endothelin-1 and the regulation of vascular tone. Clin. Exp. Pharmacol. Physiol. 22 (1995) 315-323
    • (1995) Clin. Exp. Pharmacol. Physiol. , vol.22 , pp. 315-323
    • La, M.1    Reid, J.J.2
  • 59
    • 0026623110 scopus 로고
    • Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform
    • Lamas S., Marsden P.A., Li G.K., Tempst P., and Michel T. Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 6348-6352
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 6348-6352
    • Lamas, S.1    Marsden, P.A.2    Li, G.K.3    Tempst, P.4    Michel, T.5
  • 62
    • 0029951898 scopus 로고    scopus 로고
    • Life-threatening effects of discontinuing inhaled nitric oxide in severe respiratory failure
    • Lavoie A., Hal l.J., Olson D., and Wylam M. Life-threatening effects of discontinuing inhaled nitric oxide in severe respiratory failure. Am. J. Respir. Crit. Care Med. 153 (1996) 1985-1987
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 1985-1987
    • Lavoie, A.1    Hal, l.J.2    Olson, D.3    Wylam, M.4
  • 66
    • 0026744830 scopus 로고
    • Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line
    • Lyons C.R., Orloff G.J., and Cunningham J.M. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267 (1992) 6370-6374
    • (1992) J. Biol. Chem. , vol.267 , pp. 6370-6374
    • Lyons, C.R.1    Orloff, G.J.2    Cunningham, J.M.3
  • 67
    • 0028358673 scopus 로고
    • Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch
    • Macarthur H., Warner T.D., Wood E.G., Corder R., and Vane J.R. Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch. Biochem. Biophys. Res. Commun. 200 (1994) 395-400
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , pp. 395-400
    • Macarthur, H.1    Warner, T.D.2    Wood, E.G.3    Corder, R.4    Vane, J.R.5
  • 68
    • 0026509439 scopus 로고
    • Transcriptional regulation of the endothelin-1 gene by TNF-alpha
    • Marsden P.A., and Brenner B.M. Transcriptional regulation of the endothelin-1 gene by TNF-alpha. Am. J. Physiol. 262 (1992) C854-C861
    • (1992) Am. J. Physiol. , vol.262
    • Marsden, P.A.1    Brenner, B.M.2
  • 69
    • 0023023315 scopus 로고
    • Increased superoxide anion release from human endothelial cells in response to cytokines
    • Matsubara T., and Ziff M. Increased superoxide anion release from human endothelial cells in response to cytokines. J. Immunol. 137 (1986) 3295-3298
    • (1986) J. Immunol. , vol.137 , pp. 3295-3298
    • Matsubara, T.1    Ziff, M.2
  • 70
    • 0022545164 scopus 로고
    • Superoxide anion release by human endothelial cells: synergism between a phorbol ester and a calcium ionophore
    • Matsubara T., and Ziff M. Superoxide anion release by human endothelial cells: synergism between a phorbol ester and a calcium ionophore. J. Cell. Physiol. 127 (1986) 207-210
    • (1986) J. Cell. Physiol. , vol.127 , pp. 207-210
    • Matsubara, T.1    Ziff, M.2
  • 72
    • 0026663195 scopus 로고
    • Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development
    • McElroy M.C., Postle A.D., and Kelly F.J. Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development. Biochim. Biophys. Acta 1117 (1992) 153-158
    • (1992) Biochim. Biophys. Acta , vol.1117 , pp. 153-158
    • McElroy, M.C.1    Postle, A.D.2    Kelly, F.J.3
  • 74
    • 0019082316 scopus 로고
    • Development of Crotalaria pulmonary hypertension: hemodynamic and structural study
    • Meyrick B., Gamble W., and Reid L. Development of Crotalaria pulmonary hypertension: hemodynamic and structural study. Am. J. Physiol. 239 (1980) H692-H702
    • (1980) Am. J. Physiol. , vol.239
    • Meyrick, B.1    Gamble, W.2    Reid, L.3
  • 75
    • 0242349756 scopus 로고    scopus 로고
    • Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension
    • Michelakis E.D., Tymchak W., Noga M., Webster L., Wu X.C., Lien D., Wang S.H., Modry D., and Archer S.L. Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension. Circulation 108 (2003) 2066-2069
    • (2003) Circulation , vol.108 , pp. 2066-2069
    • Michelakis, E.D.1    Tymchak, W.2    Noga, M.3    Webster, L.4    Wu, X.C.5    Lien, D.6    Wang, S.H.7    Modry, D.8    Archer, S.L.9
  • 76
    • 0029030714 scopus 로고
    • Rebound pulmonary hypertension on withdrawal from inhaled nitric oxide
    • Miller O.I., Tang S.F., Keech A., and Celermajer D.S. Rebound pulmonary hypertension on withdrawal from inhaled nitric oxide. Lancet 346 (1995) 51-52
    • (1995) Lancet , vol.346 , pp. 51-52
    • Miller, O.I.1    Tang, S.F.2    Keech, A.3    Celermajer, D.S.4
  • 78
  • 79
    • 0032907028 scopus 로고    scopus 로고
    • Effects of endogenous and exogenous nitric oxide on endothelin-1 production in cultured vascular endothelial cells
    • Mitsutomi N., Akashi C., Odagiri J., and Matsumura Y. Effects of endogenous and exogenous nitric oxide on endothelin-1 production in cultured vascular endothelial cells. Eur. J. Pharmacol. 364 (1999) 65-73
    • (1999) Eur. J. Pharmacol. , vol.364 , pp. 65-73
    • Mitsutomi, N.1    Akashi, C.2    Odagiri, J.3    Matsumura, Y.4
  • 81
    • 0031000742 scopus 로고    scopus 로고
    • Structural and functional analysis of a mutant Ras protein that is insensitive to nitric oxide activation
    • Mott H.R., Carpenter J.W., and Campbell S.L. Structural and functional analysis of a mutant Ras protein that is insensitive to nitric oxide activation. Biochemistry (Mosc) 36 (1997) 3640-3644
    • (1997) Biochemistry (Mosc) , vol.36 , pp. 3640-3644
    • Mott, H.R.1    Carpenter, J.W.2    Campbell, S.L.3
  • 82
    • 0024851677 scopus 로고
    • Nitric oxide synthesis in endothelial cytosol: evidence for a calcium-dependent and a calcium-independent mechanism
    • Mulsch A., Bassenge E., and Busse R. Nitric oxide synthesis in endothelial cytosol: evidence for a calcium-dependent and a calcium-independent mechanism. Naunyn-Schmiedebergs Arch. Pharmacol. 340 (1989) 767-770
    • (1989) Naunyn-Schmiedebergs Arch. Pharmacol. , vol.340 , pp. 767-770
    • Mulsch, A.1    Bassenge, E.2    Busse, R.3
  • 83
    • 0028799761 scopus 로고
    • Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance
    • Munzel T., Sayegh H., Freeman B.A., Tarpey M.M., and Harrison D.G. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. J. Clin. Invest. 95 (1995) 187-194
    • (1995) J. Clin. Invest. , vol.95 , pp. 187-194
    • Munzel, T.1    Sayegh, H.2    Freeman, B.A.3    Tarpey, M.M.4    Harrison, D.G.5
  • 84
    • 0022481682 scopus 로고
    • Cyclic guanosine monophosphate as a mediator of vasodilation
    • Murad F. Cyclic guanosine monophosphate as a mediator of vasodilation. J. Clin. Invest. 78 (1986) 1-5
    • (1986) J. Clin. Invest. , vol.78 , pp. 1-5
    • Murad, F.1
  • 85
    • 0026515139 scopus 로고
    • Interaction between endothelium derived relaxing factors, nitrothiols and endothelin-1 on Ca2+ mobilization in rat vascular smooth muscle cells
    • Okishio M., Ohkawa S., Ichimori Y., and Kondo K. Interaction between endothelium derived relaxing factors, nitrothiols and endothelin-1 on Ca2+ mobilization in rat vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 183 (1992) 849-855
    • (1992) Biochem. Biophys. Res. Commun. , vol.183 , pp. 849-855
    • Okishio, M.1    Ohkawa, S.2    Ichimori, Y.3    Kondo, K.4
  • 86
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from l-arginine
    • Palmer R.M.J., Ashton D.S., and Moncada S. Vascular endothelial cells synthesize nitric oxide from l-arginine. Nature 333 (1988) 664-666
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.J.1    Ashton, D.S.2    Moncada, S.3
  • 88
    • 0032133423 scopus 로고    scopus 로고
    • Antioxidant enzyme regulation and resistance to oxidants of human bronchial epithelial cells cultured under hyperoxic conditions
    • Pietarinen-Runtti P., Raivio K.O., Saksela M., Asikainen T.M., and Kinnula V.L. Antioxidant enzyme regulation and resistance to oxidants of human bronchial epithelial cells cultured under hyperoxic conditions. Am. J. Respir. Cell Mol. Biol. 19 (1998) 286-292
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.19 , pp. 286-292
    • Pietarinen-Runtti, P.1    Raivio, K.O.2    Saksela, M.3    Asikainen, T.M.4    Kinnula, V.L.5
  • 89
    • 0022853501 scopus 로고
    • Pulmonary artery endothelial abnormalities in patients with congenital heart defects and pulmonary hypertension. A correlation of light with scanning electron microscopy and transmission electron microscopy
    • Rabinovitch M., Bothwell T., Hayakawa B.N., Williams W.G., Trusler G.A., Rowe R.D., Olley P.M., and Cutz E. Pulmonary artery endothelial abnormalities in patients with congenital heart defects and pulmonary hypertension. A correlation of light with scanning electron microscopy and transmission electron microscopy. Lab. Invest. 55 (1986) 632-653
    • (1986) Lab. Invest. , vol.55 , pp. 632-653
    • Rabinovitch, M.1    Bothwell, T.2    Hayakawa, B.N.3    Williams, W.G.4    Trusler, G.A.5    Rowe, R.D.6    Olley, P.M.7    Cutz, E.8
  • 90
    • 0000590037 scopus 로고
    • Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression
    • Rao G., and Berk B. Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression. Circ. Res. 18 (1992) 775-794
    • (1992) Circ. Res. , vol.18 , pp. 775-794
    • Rao, G.1    Berk, B.2
  • 91
    • 1442330336 scopus 로고    scopus 로고
    • S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity
    • Ravi K., Brennan L.A., Levic S., Ross P.A., and Black S.M. S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 2619-2624
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 2619-2624
    • Ravi, K.1    Brennan, L.A.2    Levic, S.3    Ross, P.A.4    Black, S.M.5
  • 92
    • 0029918681 scopus 로고    scopus 로고
    • Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells
    • Redmond E.M., Cahill P.A., Hodges R., Zhang S., and Sitzmann J.V. Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells. J. Cell. Physiol. 166 (1996) 469-479
    • (1996) J. Cell. Physiol. , vol.166 , pp. 469-479
    • Redmond, E.M.1    Cahill, P.A.2    Hodges, R.3    Zhang, S.4    Sitzmann, J.V.5
  • 93
    • 0025058208 scopus 로고
    • Developmental expression of antioxidant enzymes in guinea pig lung and liver
    • Rickett G.M., and Kelly F.J. Developmental expression of antioxidant enzymes in guinea pig lung and liver. Development 108 (1990) 331-336
    • (1990) Development , vol.108 , pp. 331-336
    • Rickett, G.M.1    Kelly, F.J.2
  • 95
    • 0027241856 scopus 로고
    • A pathogenesis of atherosclerosis: a perspective for the 1990s
    • Ross R. A pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362 (1993) 801-809
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 96
    • 0034813319 scopus 로고    scopus 로고
    • Reciprocal regulation of endothelin-1 and nitric oxide: relevance in the physiology and pathology of the cardiovascular system
    • Rossi G.P., Seccia T.M., and Nussdorfer G.G. Reciprocal regulation of endothelin-1 and nitric oxide: relevance in the physiology and pathology of the cardiovascular system. Int. Rev. Cytol. 209 (2001) 241-272
    • (2001) Int. Rev. Cytol. , vol.209 , pp. 241-272
    • Rossi, G.P.1    Seccia, T.M.2    Nussdorfer, G.G.3
  • 97
    • 0022516979 scopus 로고
    • Flow-induced release of endothelium-derived relaxing factor
    • Rubanyi G.M., Romero J.C., and Vanhoutte P.M. Flow-induced release of endothelium-derived relaxing factor. Am. J. Physiol. 250 (1986) H1145-H1149
    • (1986) Am. J. Physiol. , vol.250
    • Rubanyi, G.M.1    Romero, J.C.2    Vanhoutte, P.M.3
  • 98
    • 0025605930 scopus 로고
    • Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
    • Sakurai T., Yanagisawa M., Takuwa Y., Miyyazaki H., Kimura S., Goto K., and Masaki T. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 348 (1990) 732-735
    • (1990) Nature , vol.348 , pp. 732-735
    • Sakurai, T.1    Yanagisawa, M.2    Takuwa, Y.3    Miyyazaki, H.4    Kimura, S.5    Goto, K.6    Masaki, T.7
  • 100
    • 0027155417 scopus 로고
    • Genomic analysis and expression patterns reveal distinct genes for endothelial and brain nitric oxide synthase
    • Sessa W.C., Harrison J.K., Luthin D.R., Pollock J.S., and Lynch K.R. Genomic analysis and expression patterns reveal distinct genes for endothelial and brain nitric oxide synthase. Hypertension 21 (1993) 934-938
    • (1993) Hypertension , vol.21 , pp. 934-938
    • Sessa, W.C.1    Harrison, J.K.2    Luthin, D.R.3    Pollock, J.S.4    Lynch, K.R.5
  • 101
    • 0031836090 scopus 로고    scopus 로고
    • Nitric oxide exposure inhibits endothelial NOS activity but not gene expression: a role for superoxide
    • Sheehy A.M., Burson M.A., and Black S.M. Nitric oxide exposure inhibits endothelial NOS activity but not gene expression: a role for superoxide. Am. J. Physiol. 274 (1998) L833-L841
    • (1998) Am. J. Physiol. , vol.274
    • Sheehy, A.M.1    Burson, M.A.2    Black, S.M.3
  • 104
    • 0036334770 scopus 로고    scopus 로고
    • Nitric oxide gas decreases endothelin-1 mRNA in cultured pulmonary artery endothelial cells
    • Smith A.P., Demoncheaux E.A., and Higenbottam T.W. Nitric oxide gas decreases endothelin-1 mRNA in cultured pulmonary artery endothelial cells. Nitric Oxide 6 (2002) 153-159
    • (2002) Nitric Oxide , vol.6 , pp. 153-159
    • Smith, A.P.1    Demoncheaux, E.A.2    Higenbottam, T.W.3
  • 105
    • 0029925181 scopus 로고    scopus 로고
    • Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
    • Stephens N.G., Parsons A., Schofield P.M., Kelly F., Cheeseman K., and Mitchinson M.J. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 347 (1996) 781-786
    • (1996) Lancet , vol.347 , pp. 781-786
    • Stephens, N.G.1    Parsons, A.2    Schofield, P.M.3    Kelly, F.4    Cheeseman, K.5    Mitchinson, M.J.6
  • 106
  • 108
    • 0027998055 scopus 로고
    • Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan)
    • Teerlink J.R., Loffler B.M., Hess P., Maire J.P., Clozel M., and Clozel J.P. Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan). Circulation 90 (1994) 2510-2518
    • (1994) Circulation , vol.90 , pp. 2510-2518
    • Teerlink, J.R.1    Loffler, B.M.2    Hess, P.3    Maire, J.P.4    Clozel, M.5    Clozel, J.P.6
  • 109
    • 0037155131 scopus 로고    scopus 로고
    • Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway
    • Thomas S.R., Chen K., and Keaney Jr. J.F. Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway. J. Biol. Chem. 277 (2002) 6017-6024
    • (2002) J. Biol. Chem. , vol.277 , pp. 6017-6024
    • Thomas, S.R.1    Chen, K.2    Keaney Jr., J.F.3
  • 113
    • 1442299824 scopus 로고    scopus 로고
    • Molecular mechanisms of nitric oxide-induced growth arrest and apoptosis in fetal pulmonary arterial smooth muscle cells
    • Wedgwood S., and Black S.M. Molecular mechanisms of nitric oxide-induced growth arrest and apoptosis in fetal pulmonary arterial smooth muscle cells. Nitric Oxide 9 (2003) 201-210
    • (2003) Nitric Oxide , vol.9 , pp. 201-210
    • Wedgwood, S.1    Black, S.M.2
  • 114
    • 0345690185 scopus 로고    scopus 로고
    • Role of reactive oxygen species in vascular remodeling associated with pulmonary hypertension
    • Wedgwood S., and Black S.M. Role of reactive oxygen species in vascular remodeling associated with pulmonary hypertension. Antioxid. Redox Signal. 5 (2003) 759-769
    • (2003) Antioxid. Redox Signal. , vol.5 , pp. 759-769
    • Wedgwood, S.1    Black, S.M.2
  • 115
    • 13644260463 scopus 로고    scopus 로고
    • Endothelin-1 decreases endothelial NOS expression and activity through ETA receptor-mediated generation of hydrogen peroxide
    • Wedgwood S., and Black S.M. Endothelin-1 decreases endothelial NOS expression and activity through ETA receptor-mediated generation of hydrogen peroxide. Am. J. Physiol., Lung Cell. Mol. Physiol. 288 (2005) L480-L487
    • (2005) Am. J. Physiol., Lung Cell. Mol. Physiol. , vol.288
    • Wedgwood, S.1    Black, S.M.2
  • 116
    • 0035195281 scopus 로고    scopus 로고
    • ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species
    • Wedgwood S., Dettman R., and Black S.M. ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species. Am. J. Physiol., Lung Cell. Mol. Physiol. 281 (2001) L1058-L1067
    • (2001) Am. J. Physiol., Lung Cell. Mol. Physiol. , vol.281
    • Wedgwood, S.1    Dettman, R.2    Black, S.M.3
  • 117
    • 0035903240 scopus 로고    scopus 로고
    • Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy
    • Wedgwood S., McMullan D.M., Bekker J.M., Fineman J.R., and Black S.M. Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy. Circ. Res. 89 (2001) 357-364
    • (2001) Circ. Res. , vol.89 , pp. 357-364
    • Wedgwood, S.1    McMullan, D.M.2    Bekker, J.M.3    Fineman, J.R.4    Black, S.M.5
  • 120
    • 0028059994 scopus 로고
    • Developmental effects of endothelin-1 on the pulmonary circulation in sheep
    • Wong J., Vanderford P.A., Fineman J.R., and Soifer S.J. Developmental effects of endothelin-1 on the pulmonary circulation in sheep. Pediatr. Res. 36 (1994) 394-401
    • (1994) Pediatr. Res. , vol.36 , pp. 394-401
    • Wong, J.1    Vanderford, P.A.2    Fineman, J.R.3    Soifer, S.J.4
  • 121
    • 0028985622 scopus 로고
    • Endothelin b receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension
    • Wong J., Vanderford P.A., Winters J., Soifer S.J., and Fineman J.R. Endothelin b receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension. J. Cardiovasc. Pharmacol. 25 (1995) 207-215
    • (1995) J. Cardiovasc. Pharmacol. , vol.25 , pp. 207-215
    • Wong, J.1    Vanderford, P.A.2    Winters, J.3    Soifer, S.J.4    Fineman, J.R.5
  • 123
    • 0025838213 scopus 로고
    • Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation
    • Yoshibayashi M., Nishioka K., Nakao K., Saito Y., Matsumura M., Ueda T., Temma S., Shirakami G., Imura H., and Mikawa H. Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation. Circulation 84 (1991) 2280-2285
    • (1991) Circulation , vol.84 , pp. 2280-2285
    • Yoshibayashi, M.1    Nishioka, K.2    Nakao, K.3    Saito, Y.4    Matsumura, M.5    Ueda, T.6    Temma, S.7    Shirakami, G.8    Imura, H.9    Mikawa, H.10
  • 124
    • 0030053760 scopus 로고    scopus 로고
    • Differential patterns of antioxidant enzyme mRNA expression in guinea pig lung and liver during development
    • Yuan H.T., Bingle C.D., and Kelly F.J. Differential patterns of antioxidant enzyme mRNA expression in guinea pig lung and liver during development. Biochim. Biophys. Acta 1305 (1996) 163-171
    • (1996) Biochim. Biophys. Acta , vol.1305 , pp. 163-171
    • Yuan, H.T.1    Bingle, C.D.2    Kelly, F.J.3
  • 125
    • 0036199685 scopus 로고    scopus 로고
    • Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite
    • Zou M.H., Shi C., and Cohen R.A. Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J. Clin. Invest. 109 (2002) 817-826
    • (2002) J. Clin. Invest. , vol.109 , pp. 817-826
    • Zou, M.H.1    Shi, C.2    Cohen, R.A.3


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