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Volumn 9, Issue 2, 2008, Pages 159-168

Nitric oxide metabolism and the acute chest syndrome of sickle cell anemia

Author keywords

Acute chest syndrome; Critical illness; Nitric oxide; Pulmonary hypertension; Sickle cell anemia; Vasoocclusive crisis

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; CEPHALOSPORIN; DEXAMETHASONE; HEMOGLOBIN; MACROLIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; OXYGEN;

EID: 40449121926     PISSN: 15297535     EISSN: None     Source Type: Journal    
DOI: 10.1097/PCC.0b013e3181668ca9     Document Type: Review
Times cited : (15)

References (145)
  • 1
    • 0028234283 scopus 로고
    • The acute chest syndrome in sickle cell disease: Incidence and risk factors. The Cooperative Study of Sickle Cell Disease
    • O Castro DJ Brambilla B Thorington The acute chest syndrome in sickle cell disease: Incidence and risk factors. The Cooperative Study of Sickle Cell Disease Blood 84 1994 643 649
    • (1994) Blood , vol.84 , pp. 643-649
    • Castro, O1    Brambilla, DJ2    Thorington, B3
  • 2
    • 0025914624 scopus 로고
    • Patterns of mortality in sickle cell disease in the United Kingdom
    • A Gray EN Anionwu SC Davies Patterns of mortality in sickle cell disease in the United Kingdom J Clin Pathol 44 1991 459 463
    • (1991) J Clin Pathol , vol.44 , pp. 459-463
    • Gray, A1    Anionwu, EN2    Davies, SC3
  • 3
    • 0019989752 scopus 로고
    • Causes of death in sickle-cell disease in Jamaica
    • AN Thomas C Pattison GR Serjeant Causes of death in sickle-cell disease in Jamaica BMJ (Clin Res Ed) 285 1982 633 635
    • (1982) BMJ (Clin Res Ed) , vol.285 , pp. 633-635
    • Thomas, AN1    Pattison, C2    Serjeant, GR3
  • 4
    • 0030463369 scopus 로고    scopus 로고
    • Endothelial function in different organs
    • E Bassenge Endothelial function in different organs Prog Cardiovasc Dis 39 1996 209 228
    • (1996) Prog Cardiovasc Dis , vol.39 , pp. 209-228
    • Bassenge, E1
  • 5
    • 0029089199 scopus 로고
    • Sickle erythrocytes, after sickling, regulate the expression of the endothelin-1 gene and protein in human endothelial cells in culture
    • M Phelan SP Perrine M Brauer Sickle erythrocytes, after sickling, regulate the expression of the endothelin-1 gene and protein in human endothelial cells in culture J Clin Invest 96 1995 1145 1151
    • (1995) J Clin Invest , vol.96 , pp. 1145-1151
    • Phelan, M1    Perrine, SP2    Brauer, M3
  • 6
    • 0032189803 scopus 로고    scopus 로고
    • Plasma endothelin-1, cytokine, and prostaglandin E2 levels in sickle cell disease and acute vaso-occlusive sickle crisis
    • E Graido-Gonzalez JC Doherty EW Bergreen Plasma endothelin-1, cytokine, and prostaglandin E2 levels in sickle cell disease and acute vaso-occlusive sickle crisis Blood 92 1998 2551 2555
    • (1998) Blood , vol.92 , pp. 2551-2555
    • Graido-Gonzalez, E1    Doherty, JC2    Bergreen, EW3
  • 7
    • 0037149718 scopus 로고    scopus 로고
    • Bosentan therapy for pulmonary arterial hypertension
    • LJ Rubin DB Badesch RJ Barst Bosentan therapy for pulmonary arterial hypertension N Engl J Med 346 2002 896 903
    • (2002) N Engl J Med , vol.346 , pp. 896-903
    • Rubin, LJ1    Badesch, DB2    Barst, RJ3
  • 8
    • 0030739926 scopus 로고    scopus 로고
    • Endothelin-1 production during the acute chest syndrome in sickle cell disease
    • SI Hammerman S Kourembanas TJ Conca Endothelin-1 production during the acute chest syndrome in sickle cell disease Am J Respir Crit Care Med 156 1997 280 285
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 280-285
    • Hammerman, SI1    Kourembanas, S2    Conca, TJ3
  • 9
    • 0028894111 scopus 로고
    • Sickle reticulocytes adhere to VCAM-1
    • BE Gee OS Platt Sickle reticulocytes adhere to VCAM-1 Blood 85 1995 268 274
    • (1995) Blood , vol.85 , pp. 268-274
    • Gee, BE1    Platt, OS2
  • 10
    • 0027184968 scopus 로고
    • Alpha 4 beta 1-integrin expression on sickle reticulocytes: vascular cell adhesion molecule-1-dependent binding to endothelium
    • RA Swerlick JR Eckman A Kumar Alpha 4 beta 1-integrin expression on sickle reticulocytes: vascular cell adhesion molecule-1-dependent binding to endothelium Blood 82 1993 1891 1899
    • (1993) Blood , vol.82 , pp. 1891-1899
    • Swerlick, RA1    Eckman, JR2    Kumar, A3
  • 11
    • 0018885938 scopus 로고
    • Erythrocyte adherence to endothelium in sickle-cell anemia: A possible determinant of disease severity
    • RP Hebbel MA Boogaerts JW Eaton Erythrocyte adherence to endothelium in sickle-cell anemia: A possible determinant of disease severity N Engl J Med 302 1980 992 995
    • (1980) N Engl J Med , vol.302 , pp. 992-995
    • Hebbel, RP1    Boogaerts, MA2    Eaton, JW3
  • 12
    • 0030119698 scopus 로고    scopus 로고
    • CD36-positive stress reticulocytosis in sickle cell anemia
    • PV Browne RP Hebbel CD36-positive stress reticulocytosis in sickle cell anemia J Lab Clin Med 127 1996 340 347
    • (1996) J Lab Clin Med , vol.127 , pp. 340-347
    • Browne, PV1    Hebbel, RP2
  • 13
    • 0027252053 scopus 로고
    • Sickle erythrocyte-endothelial interactions in microcirculation: The role of von Willebrand factor and implications for vasoocclusion
    • DK Kaul RL Nagel D Chen Sickle erythrocyte-endothelial interactions in microcirculation: The role of von Willebrand factor and implications for vasoocclusion Blood 81 1993 2429 2438
    • (1993) Blood , vol.81 , pp. 2429-2438
    • Kaul, DK1    Nagel, RL2    Chen, D3
  • 14
    • 0030703240 scopus 로고    scopus 로고
    • Circulating activated endothelial cells in sickle cell anemia
    • A Solovey Y Lin P Browne Circulating activated endothelial cells in sickle cell anemia N Engl J Med 337 1997 1584 1590
    • (1997) N Engl J Med , vol.337 , pp. 1584-1590
    • Solovey, A1    Lin, Y2    Browne, P3
  • 15
    • 0015787513 scopus 로고
    • Platelet function and survival in sickle cell disease
    • MJ Haut DH Cowan JW Harris Platelet function and survival in sickle cell disease J Lab Clin Med 82 1973 44 53
    • (1973) J Lab Clin Med , vol.82 , pp. 44-53
    • Haut, MJ1    Cowan, DH2    Harris, JW3
  • 16
    • 0019119627 scopus 로고
    • Significance of plasma beta-thromboglobulin values in patients with sickle cell disease
    • P Mehta Significance of plasma beta-thromboglobulin values in patients with sickle cell disease J Pediatr 97 1980 941 944
    • (1980) J Pediatr , vol.97 , pp. 941-944
    • Mehta, P1
  • 17
    • 0028322292 scopus 로고
    • Elevated urinary levels of thromboxane and prostacyclin metabolites in sickle cell disease reflects activated platelets in the circulation
    • J Kurantsin-Mills BO Ibe CL Natta Elevated urinary levels of thromboxane and prostacyclin metabolites in sickle cell disease reflects activated platelets in the circulation Br J Haematol 87 1994 580 585
    • (1994) Br J Haematol , vol.87 , pp. 580-585
    • Kurantsin-Mills, J1    Ibe, BO2    Natta, CL3
  • 18
    • 0026578172 scopus 로고
    • Platelet regulatory prostanoids and platelet release products in sickle cell disease
    • GL Longenecker BJ Beyers VN Mankad Platelet regulatory prostanoids and platelet release products in sickle cell disease Am J Hematol 40 1992 12 19
    • (1992) Am J Hematol , vol.40 , pp. 12-19
    • Longenecker, GL1    Beyers, BJ2    Mankad, VN3
  • 19
    • 0018842912 scopus 로고
    • Abnormalities of platelet aggregation in sickle cell disease
    • P Mehta J Mehta Abnormalities of platelet aggregation in sickle cell disease J Pediatr 96 1980 209 213
    • (1980) J Pediatr , vol.96 , pp. 209-213
    • Mehta, P1    Mehta, J2
  • 20
    • 0026689393 scopus 로고
    • Enhanced platelet reactivity and hypercoagulability in the steady state of sickle cell anaemia
    • SI Berney CD Ridler AD Stephens Enhanced platelet reactivity and hypercoagulability in the steady state of sickle cell anaemia Am J Hematol 40 1992 290 294
    • (1992) Am J Hematol , vol.40 , pp. 290-294
    • Berney, SI1    Ridler, CD2    Stephens, AD3
  • 21
    • 0028903653 scopus 로고
    • Changes in coagulation and fibrinolysis in patients with sickle cell disease compared with healthy black controls
    • D Hagger S Wolff J Owen Changes in coagulation and fibrinolysis in patients with sickle cell disease compared with healthy black controls Blood Coagul Fibrinolysis 6 1995 93 99
    • (1995) Blood Coagul Fibrinolysis , vol.6 , pp. 93-99
    • Hagger, D1    Wolff, S2    Owen, J3
  • 22
    • 0032423610 scopus 로고    scopus 로고
    • Prothrombotic changes in children with sickle cell disease: relationships to cerebrovascular disease and transfusion
    • R Liesner I Mackie J Cookson Prothrombotic changes in children with sickle cell disease: relationships to cerebrovascular disease and transfusion Br J Haematol 103 1998 1037 1044
    • (1998) Br J Haematol , vol.103 , pp. 1037-1044
    • Liesner, R1    Mackie, I2    Cookson, J3
  • 23
    • 0027957535 scopus 로고
    • Enhanced thrombin generation in children with sickle cell disease
    • M Peters BE Plaat H ten Cate Enhanced thrombin generation in children with sickle cell disease Thromb Haemost 71 1994 169 172
    • (1994) Thromb Haemost , vol.71 , pp. 169-172
    • Peters, M1    Plaat, BE2    ten Cate, H3
  • 24
    • 0015076254 scopus 로고
    • Pulmonary changes in sickle cell disease
    • EH Oppenheimer JR Esterly Pulmonary changes in sickle cell disease Am Rev Respir Dis 103 1971 858 859
    • (1971) Am Rev Respir Dis , vol.103 , pp. 858-859
    • Oppenheimer, EH1    Esterly, JR2
  • 25
    • 0035187093 scopus 로고    scopus 로고
    • Pulmonary thrombotic arteriopathy in patients with sickle cell disease
    • M Adedeji J Cespedes K Allen Pulmonary thrombotic arteriopathy in patients with sickle cell disease Arch Pathol Lab Med 125 2001 1436 1441
    • (2001) Arch Pathol Lab Med , vol.125 , pp. 1436-1441
    • Adedeji, M1    Cespedes, J2    Allen, K3
  • 26
    • 0034307274 scopus 로고    scopus 로고
    • Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion
    • JD Belcher PH Marker JP Weber Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion Blood 96 2000 2451 2459
    • (2000) Blood , vol.96 , pp. 2451-2459
    • Belcher, JD1    Marker, PH2    Weber, JP3
  • 27
    • 17144415622 scopus 로고    scopus 로고
    • Effect of cytokines and chemokines on sickle neutrophil adhesion to fibronectin
    • A Assis N Conran AA Canalli Effect of cytokines and chemokines on sickle neutrophil adhesion to fibronectin Acta Haematol 113 2005 130 136
    • (2005) Acta Haematol , vol.113 , pp. 130-136
    • Assis, A1    Conran, N2    Canalli, AA3
  • 28
    • 0025896401 scopus 로고
    • Results of bronchoscopically obtained lower airway cultures from adult sickle cell disease patients with the acute chest syndrome
    • MB Kirkpatrick J Haynes Jr JB Bass Jr Results of bronchoscopically obtained lower airway cultures from adult sickle cell disease patients with the acute chest syndrome Am J Med 90 1991 206 210
    • (1991) Am J Med , vol.90 , pp. 206-210
    • Kirkpatrick, MB1    Haynes, J2    Bass, JB3
  • 29
    • 0026074569 scopus 로고
    • Role of Chlamydia pneumoniae in acute chest syndrome of sickle cell disease
    • ST Miller MR Hammerschlag K Chirgwin Role of Chlamydia pneumoniae in acute chest syndrome of sickle cell disease J Pediatr 118 1991 30 33
    • (1991) J Pediatr , vol.118 , pp. 30-33
    • Miller, ST1    Hammerschlag, MR2    Chirgwin, K3
  • 30
    • 0025735533 scopus 로고
    • Rib infarcts and acute chest syndrome in sickle cell diseases
    • DL Rucknagel KA Kalinyak MJ Gelfand Rib infarcts and acute chest syndrome in sickle cell diseases Lancet 337 1991 831 833
    • (1991) Lancet , vol.337 , pp. 831-833
    • Rucknagel, DL1    Kalinyak, KA2    Gelfand, MJ3
  • 31
    • 0026537092 scopus 로고
    • Rib infarcts in sickling disease
    • WP Cockshott Rib infarcts in sickling disease Eur J Radiol 14 1992 63 66
    • (1992) Eur J Radiol , vol.14 , pp. 63-66
    • Cockshott, WP1
  • 32
    • 0029665150 scopus 로고    scopus 로고
    • Phospholipase A2 levels in acute chest syndrome of sickle cell disease
    • LA Styles CG Schalkwijk AJ Aarsman Phospholipase A2 levels in acute chest syndrome of sickle cell disease Blood 87 1996 2573 2578
    • (1996) Blood , vol.87 , pp. 2573-2578
    • Styles, LA1    Schalkwijk, CG2    Aarsman, AJ3
  • 33
    • 0028244891 scopus 로고
    • Pulmonary fat embolism: A distinct cause of severe acute chest syndrome in sickle cell anemia
    • E Vichinsky R Williams M Das Pulmonary fat embolism: A distinct cause of severe acute chest syndrome in sickle cell anemia Blood 83 1994 3107 3112
    • (1994) Blood , vol.83 , pp. 3107-3112
    • Vichinsky, E1    Williams, R2    Das, M3
  • 34
    • 0025209822 scopus 로고
    • Massive fat and necrotic bone marrow embolization in a previously undiagnosed patient with sickle cell disease
    • JA Garza Massive fat and necrotic bone marrow embolization in a previously undiagnosed patient with sickle cell disease Am J Forensic Med Pathol 11 1990 83 88
    • (1990) Am J Forensic Med Pathol , vol.11 , pp. 83-88
    • Garza, JA1
  • 35
    • 0029926694 scopus 로고    scopus 로고
    • The release of nitric oxide and superoxide anion by neutrophils and mononuclear cells from patients with sickle cell anaemia
    • P Dias-Da-Motta VR Arruda MN Muscara The release of nitric oxide and superoxide anion by neutrophils and mononuclear cells from patients with sickle cell anaemia Br J Haematol 93 1996 333 340
    • (1996) Br J Haematol , vol.93 , pp. 333-340
    • Dias-Da-Motta, P1    Arruda, VR2    Muscara, MN3
  • 36
    • 0029900905 scopus 로고    scopus 로고
    • Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury
    • Y Xia VL Dawson TM Dawson Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury Proc Natl Acad Sci U S A 93 1996 6770 6774
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 6770-6774
    • Xia, Y1    Dawson, VL2    Dawson, TM3
  • 38
    • 0023833103 scopus 로고
    • Altered amount and activity of superoxide dismutase in sickle cell anemia
    • L Schacter JA Warth EM Gordon Altered amount and activity of superoxide dismutase in sickle cell anemia FASEB J 2 1988 237 243
    • (1988) FASEB J , vol.2 , pp. 237-243
    • Schacter, L1    Warth, JA2    Gordon, EM3
  • 39
    • 0020393217 scopus 로고
    • Spontaneous oxygen radical generation by sickle erythrocytes
    • RP Hebbel JW Eaton M Balasingam Spontaneous oxygen radical generation by sickle erythrocytes J Clin Invest 70 1982 1253 1259
    • (1982) J Clin Invest , vol.70 , pp. 1253-1259
    • Hebbel, RP1    Eaton, JW2    Balasingam, M3
  • 40
    • 0035909930 scopus 로고    scopus 로고
    • Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease
    • M Aslan TM Ryan B Adler Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease Proc Natl Acad Sci U S A 98 2001 15215 15220
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 15215-15220
    • Aslan, M1    Ryan, TM2    Adler, B3
  • 41
    • 0024706628 scopus 로고
    • Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein
    • LJ Ignarro Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein Circ Res 65 1989 1 21
    • (1989) Circ Res , vol.65 , pp. 1-21
    • Ignarro, LJ1
  • 42
    • 0025863009 scopus 로고
    • Endothelium-derived relaxing factor: basic review and clinical implications
    • RA Johns Endothelium-derived relaxing factor: basic review and clinical implications J Cardiothorac Vasc Anesth 5 1991 69 79
    • (1991) J Cardiothorac Vasc Anesth , vol.5 , pp. 69-79
    • Johns, RA1
  • 43
    • 0026002686 scopus 로고
    • Hypoxia induces endothelin gene expression and secretion in cultured human endothelium
    • S Kourembanas PA Marsden LP McQuillan Hypoxia induces endothelin gene expression and secretion in cultured human endothelium J Clin Invest 88 1991 1054 1057
    • (1991) J Clin Invest , vol.88 , pp. 1054-1057
    • Kourembanas, S1    Marsden, PA2    McQuillan, LP3
  • 44
    • 0025977583 scopus 로고
    • Endothelium-derived relaxing factor inhibits hypoxic pulmonary vasoconstriction in rats
    • SF Liu DE Crawley PJ Barnes Endothelium-derived relaxing factor inhibits hypoxic pulmonary vasoconstriction in rats Am Rev Respir Dis 143 1991 32 37
    • (1991) Am Rev Respir Dis , vol.143 , pp. 32-37
    • Liu, SF1    Crawley, DE2    Barnes, PJ3
  • 45
    • 0026499197 scopus 로고
    • Endothelial vasomotor regulation in health and disease
    • NR Searle P Sahab Endothelial vasomotor regulation in health and disease Can J Anaesth 39 1992 838 857
    • (1992) Can J Anaesth , vol.39 , pp. 838-857
    • Searle, NR1    Sahab, P2
  • 46
    • 0031901747 scopus 로고    scopus 로고
    • Molecular biology of nitric oxide synthases
    • DA Geller TR Billiar Molecular biology of nitric oxide synthases Cancer Metastasis Rev 17 1998 7 23
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 7-23
    • Geller, DA1    Billiar, TR2
  • 47
    • 0028357682 scopus 로고
    • Nitric oxide: Basic science and clinical applications
    • PC Kam G Govender Nitric oxide: Basic science and clinical applications Anaesthesia 49 1994 515 521
    • (1994) Anaesthesia , vol.49 , pp. 515-521
    • Kam, PC1    Govender, G2
  • 48
    • 0028270719 scopus 로고
    • Regulation of biosynthesis of nitric oxide
    • C Nathan QW Xie Regulation of biosynthesis of nitric oxide J Biol Chem 269 1994 13725 13728
    • (1994) J Biol Chem , vol.269 , pp. 13725-13728
    • Nathan, C1    Xie, QW2
  • 49
    • 0034186090 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and inflammatory diseases
    • R Zamora Y Vodovotz TR Billiar Inducible nitric oxide synthase and inflammatory diseases Mol Med 6 2000 347 373
    • (2000) Mol Med , vol.6 , pp. 347-373
    • Zamora, R1    Vodovotz, Y2    Billiar, TR3
  • 50
    • 0036020220 scopus 로고    scopus 로고
    • Expression of the liver form of arginase in erythrocytes
    • PS Kim RK Iyer KV Lu Expression of the liver form of arginase in erythrocytes Mol Genet Metab 76 2002 100 110
    • (2002) Mol Genet Metab , vol.76 , pp. 100-110
    • Kim, PS1    Iyer, RK2    Lu, KV3
  • 51
    • 0036402941 scopus 로고    scopus 로고
    • Regulation of enzymes of the urea cycle and arginine metabolism
    • SM Morris Jr Regulation of enzymes of the urea cycle and arginine metabolism Annu Rev Nutr 22 2002 87 105
    • (2002) Annu Rev Nutr , vol.22 , pp. 87-105
    • Morris, SM1
  • 52
    • 0034618752 scopus 로고    scopus 로고
    • Regulation of nitric oxide production by arginine metabolic enzymes
    • M Mori T Gotoh Regulation of nitric oxide production by arginine metabolic enzymes Biochem Biophys Res Commun 275 2000 715 719
    • (2000) Biochem Biophys Res Commun , vol.275 , pp. 715-719
    • Mori, M1    Gotoh, T2
  • 53
    • 0035079905 scopus 로고    scopus 로고
    • The transport activity of the human cationic amino acid transporter hCAT-1 is downregulated by activation of protein kinase C
    • P Graf U Forstermann EI Closs The transport activity of the human cationic amino acid transporter hCAT-1 is downregulated by activation of protein kinase C Br J Pharmacol 132 2001 1193 1200
    • (2001) Br J Pharmacol , vol.132 , pp. 1193-1200
    • Graf, P1    Forstermann, U2    Closs, EI3
  • 54
    • 0033960571 scopus 로고    scopus 로고
    • Association of L-arginine transporters with fodrin: Implications for hypoxic inhibition of arginine uptake
    • SI Zharikov ER Block Association of L-arginine transporters with fodrin: Implications for hypoxic inhibition of arginine uptake Am J Physiol Lung Cell Mol Physiol 278 2000 L111 L117
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278 , pp. L111-L117
    • Zharikov, SI1    Block, ER2
  • 55
    • 0025892441 scopus 로고
    • N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine
    • DJ Stuehr NS Kwon CF Nathan N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine J Biol Chem 266 1991 6259 6263
    • (1991) J Biol Chem , vol.266 , pp. 6259-6263
    • Stuehr, DJ1    Kwon, NS2    Nathan, CF3
  • 56
    • 0032787622 scopus 로고    scopus 로고
    • Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization
    • JL Boucher C Moali JP Tenu Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization Cell Mol Life Sci 55 1999 1015 1028
    • (1999) Cell Mol Life Sci , vol.55 , pp. 1015-1028
    • Boucher, JL1    Moali, C2    Tenu, JP3
  • 58
    • 0029875840 scopus 로고    scopus 로고
    • S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control
    • L Jia C Bonaventura J Bonaventura S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control Nature 380 1996 221 226
    • (1996) Nature , vol.380 , pp. 221-226
    • Jia, L1    Bonaventura, C2    Bonaventura, J3
  • 59
    • 0030791742 scopus 로고    scopus 로고
    • Blood flow regulation by S-nitrosohemoglobin in the physiological oxygen gradient
    • JS Stamler L Jia JP Eu Blood flow regulation by S-nitrosohemoglobin in the physiological oxygen gradient Science 276 1997 2034 2037
    • (1997) Science , vol.276 , pp. 2034-2037
    • Stamler, JS1    Jia, L2    Eu, JP3
  • 60
    • 0032495529 scopus 로고    scopus 로고
    • Reactions between nitric oxide and haemoglobin under physiological conditions
    • AJ Gow JS Stamler Reactions between nitric oxide and haemoglobin under physiological conditions Nature 391 1998 169 173
    • (1998) Nature , vol.391 , pp. 169-173
    • Gow, AJ1    Stamler, JS2
  • 61
    • 0035252076 scopus 로고    scopus 로고
    • Export by red blood cells of nitric oxide bioactivity
    • JR Pawloski DT Hess JS Stamler Export by red blood cells of nitric oxide bioactivity Nature 409 2001 622 626
    • (2001) Nature , vol.409 , pp. 622-626
    • Pawloski, JR1    Hess, DT2    Stamler, JS3
  • 62
    • 10744220361 scopus 로고    scopus 로고
    • Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation
    • K Cosby KS Partovi JH Crawford Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation Nat Med 9 2003 1498 1505
    • (2003) Nat Med , vol.9 , pp. 1498-1505
    • Cosby, K1    Partovi, KS2    Crawford, JH3
  • 63
    • 0030982523 scopus 로고    scopus 로고
    • Low concentrations of nitric oxide increase oxygen affinity of sickle erythrocytes in vitro and in vivo
    • CA Head C Brugnara R Martinez-Ruiz Low concentrations of nitric oxide increase oxygen affinity of sickle erythrocytes in vitro and in vivo J Clin Invest 100 1997 1193 1198
    • (1997) J Clin Invest , vol.100 , pp. 1193-1198
    • Head, CA1    Brugnara, C2    Martinez-Ruiz, R3
  • 64
    • 0032696892 scopus 로고    scopus 로고
    • Inhaled nitric oxide augments nitric oxide transport on sickle cell hemoglobin without affecting oxygen affinity
    • MT Gladwin AN Schechter JH Shelhamer Inhaled nitric oxide augments nitric oxide transport on sickle cell hemoglobin without affecting oxygen affinity J Clin Invest 104 1999 937 945
    • (1999) J Clin Invest , vol.104 , pp. 937-945
    • Gladwin, MT1    Schechter, AN2    Shelhamer, JH3
  • 65
    • 0033836250 scopus 로고    scopus 로고
    • Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport
    • BW Hrinczenko AI Alayash DA Wink Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport Br J Haematol 110 2000 412 419
    • (2000) Br J Haematol , vol.110 , pp. 412-419
    • Hrinczenko, BW1    Alayash, AI2    Wink, DA3
  • 66
    • 0032005770 scopus 로고    scopus 로고
    • Nitric oxide synthesis in the lung: Regulation by oxygen through a kinetic mechanism
    • RA Dweik D Laskowski HM Abu-Soud Nitric oxide synthesis in the lung: Regulation by oxygen through a kinetic mechanism J Clin Invest 101 1998 660 666
    • (1998) J Clin Invest , vol.101 , pp. 660-666
    • Dweik, RA1    Laskowski, D2    Abu-Soud, HM3
  • 67
    • 0029564274 scopus 로고
    • Effect of anemia on intrapulmonary shunt during atelectasis in rabbits
    • S Deem MJ Bishop MK Alberts Effect of anemia on intrapulmonary shunt during atelectasis in rabbits J Appl Physiol 79 1995 1951 1957
    • (1995) J Appl Physiol , vol.79 , pp. 1951-1957
    • Deem, S1    Bishop, MJ2    Alberts, MK3
  • 68
    • 0031956466 scopus 로고    scopus 로고
    • Red-blood-cell augmentation of hypoxic pulmonary vasoconstriction: hematocrit dependence and the importance of nitric oxide
    • S Deem ER Swenson MK Alberts Red-blood-cell augmentation of hypoxic pulmonary vasoconstriction: hematocrit dependence and the importance of nitric oxide Am J Respir Crit Care Med 157 1998 1181 1186
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1181-1186
    • Deem, S1    Swenson, ER2    Alberts, MK3
  • 69
    • 0023873716 scopus 로고
    • Hypoxic vasoconstriction in blood and plasma perfused lungs
    • TS Hakim AB Malik Hypoxic vasoconstriction in blood and plasma perfused lungs Respir Physiol 72 1988 109 121
    • (1988) Respir Physiol , vol.72 , pp. 109-121
    • Hakim, TS1    Malik, AB2
  • 70
    • 0029609349 scopus 로고
    • Effect of transfusion in acute chest syndrome of sickle cell disease
    • U Emre ST Miller M Gutierez Effect of transfusion in acute chest syndrome of sickle cell disease J Pediatr 127 1995 901 904
    • (1995) J Pediatr , vol.127 , pp. 901-904
    • Emre, U1    Miller, ST2    Gutierez, M3
  • 71
    • 0023928365 scopus 로고
    • Beneficial effect of blood transfusion in children with sickle cell chest syndrome
    • AA Mallouh M Asha Beneficial effect of blood transfusion in children with sickle cell chest syndrome Am J Dis Child 142 1988 178 182
    • (1988) Am J Dis Child , vol.142 , pp. 178-182
    • Mallouh, AA1    Asha, M2
  • 72
    • 0027510623 scopus 로고
    • Transfusion management of sickle cell disease
    • AS Wayne SV Kevy DG Nathan Transfusion management of sickle cell disease Blood 81 1993 1109 1123
    • (1993) Blood , vol.81 , pp. 1109-1123
    • Wayne, AS1    Kevy, SV2    Nathan, DG3
  • 73
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • UC Garg A Hassid Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells J Clin Invest 83 1989 1774 1777
    • (1989) J Clin Invest , vol.83 , pp. 1774-1777
    • Garg, UC1    Hassid, A2
  • 74
    • 0032871017 scopus 로고    scopus 로고
    • Simultaneous measurement of nitric oxide production by conducting and alveolar airways of humans
    • AP Pietropaoli IB Perillo A Torres Simultaneous measurement of nitric oxide production by conducting and alveolar airways of humans J Appl Physiol 87 1999 1532 1542
    • (1999) J Appl Physiol , vol.87 , pp. 1532-1542
    • Pietropaoli, AP1    Perillo, IB2    Torres, A3
  • 75
    • 0033769611 scopus 로고    scopus 로고
    • Exhaled nitric oxide production by nitric oxide synthase-deficient mice
    • W Steudel M Kirmse J Weimann Exhaled nitric oxide production by nitric oxide synthase-deficient mice Am J Respir Crit Care Med 162 2000 1262 1267
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1262-1267
    • Steudel, W1    Kirmse, M2    Weimann, J3
  • 76
    • 0033429105 scopus 로고    scopus 로고
    • Recommendations for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999
    • Recommendations for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999 Am J Respir Crit Care Med 160 1999 2104 2117
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 2104-2117
  • 77
    • 0031880808 scopus 로고    scopus 로고
    • Single-exhalation profiles of NO and CO2 in humans: effect of dynamically changing flow rate
    • NM Tsoukias Z Tannous AF Wilson Single-exhalation profiles of NO and CO2 in humans: effect of dynamically changing flow rate J Appl Physiol 85 1998 642 652
    • (1998) J Appl Physiol , vol.85 , pp. 642-652
    • Tsoukias, NM1    Tannous, Z2    Wilson, AF3
  • 78
    • 0037098037 scopus 로고    scopus 로고
    • Partitioning of alveolar and conducting airway nitric oxide in scleroderma lung disease
    • RE Girgis MK Gugnani J Abrams Partitioning of alveolar and conducting airway nitric oxide in scleroderma lung disease Am J Respir Crit Care Med 165 2002 1587 1591
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1587-1591
    • Girgis, RE1    Gugnani, MK2    Abrams, J3
  • 79
    • 0032536027 scopus 로고    scopus 로고
    • Effects of nitroglycerin and sodium nitroprusside on end-expiratory concentrations of nitric oxide in healthy humans
    • E Dirnberger H Lucan HG Eichler Effects of nitroglycerin and sodium nitroprusside on end-expiratory concentrations of nitric oxide in healthy humans Life Sci 62 1998 PL103 PL108
    • (1998) Life Sci , vol.62 , pp. PL103-PL108
    • Dirnberger, E1    Lucan, H2    Eichler, HG3
  • 80
    • 0032827124 scopus 로고    scopus 로고
    • Exhaled nitric oxide does not provide a marker of vascular endothelial function in healthy humans
    • C Sartori M Lepori T Busch Exhaled nitric oxide does not provide a marker of vascular endothelial function in healthy humans Am J Respir Crit Care Med 160 1999 879 882
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 879-882
    • Sartori, C1    Lepori, M2    Busch, T3
  • 81
    • 0035101798 scopus 로고    scopus 로고
    • Microscopic modeling of NO and S-nitrosoglutathione kinetics and transport in human airways
    • HY Shin SC George Microscopic modeling of NO and S-nitrosoglutathione kinetics and transport in human airways J Appl Physiol 90 2001 777 788
    • (2001) J Appl Physiol , vol.90 , pp. 777-788
    • Shin, HY1    George, SC2
  • 82
    • 0032123463 scopus 로고    scopus 로고
    • A significant proportion of exhaled nitric oxide arises in large airways in normal subjects
    • PE Silkoff PA McClean M Caramori A significant proportion of exhaled nitric oxide arises in large airways in normal subjects Respir Physiol 113 1998 33 38
    • (1998) Respir Physiol , vol.113 , pp. 33-38
    • Silkoff, PE1    McClean, PA2    Caramori, M3
  • 83
    • 33846448507 scopus 로고    scopus 로고
    • Decrease in lung nitric oxide production after peritonitis in mice with sickle cell disease
    • P Bartolucci MT Ngo Y Beuzard Decrease in lung nitric oxide production after peritonitis in mice with sickle cell disease Crit Care Med 35 2007 502 509
    • (2007) Crit Care Med , vol.35 , pp. 502-509
    • Bartolucci, P1    Ngo, MT2    Beuzard, Y3
  • 84
    • 0037114210 scopus 로고    scopus 로고
    • Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome
    • KJ Sullivan N Kissoon LJ Duckworth Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome Am J Respir Crit Care Med 164 2001 2186 2190
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 2186-2190
    • Sullivan, KJ1    Kissoon, N2    Duckworth, LJ3
  • 85
    • 0037371369 scopus 로고    scopus 로고
    • Decreased exhaled nitric oxide in sickle cell disease: relationship with chronic lung involvement
    • RE Girgis MA Qureshi J Abrams Decreased exhaled nitric oxide in sickle cell disease: relationship with chronic lung involvement Am J Hematol 72 2003 177 184
    • (2003) Am J Hematol , vol.72 , pp. 177-184
    • Girgis, RE1    Qureshi, MA2    Abrams, J3
  • 86
    • 0033841145 scopus 로고    scopus 로고
    • Production of endogenous nitric oxide in chronic obstructive pulmonary disease and patients with cor pulmonale: Correlates with echo-Doppler assessment
    • E Clini G Cremona M Campana Production of endogenous nitric oxide in chronic obstructive pulmonary disease and patients with cor pulmonale: Correlates with echo-Doppler assessment Am J Respir Crit Care Med 162 2000 446 450
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 446-450
    • Clini, E1    Cremona, G2    Campana, M3
  • 87
    • 0030483222 scopus 로고    scopus 로고
    • Nitric oxide in exhaled air is a new marker of airway inflammation
    • SA Kharitonov PJ Barnes Nitric oxide in exhaled air is a new marker of airway inflammation Monaldi Arch Chest Dis 51 1996 533 537
    • (1996) Monaldi Arch Chest Dis , vol.51 , pp. 533-537
    • Kharitonov, SA1    Barnes, PJ2
  • 88
    • 0032866612 scopus 로고    scopus 로고
    • Exhaled nitric oxide measurements in childhood asthma: Techniques and interpretation
    • N Kissoon L Duckworth K Blake Exhaled nitric oxide measurements in childhood asthma: Techniques and interpretation Pediatr Pulmonol 28 1999 282 296
    • (1999) Pediatr Pulmonol , vol.28 , pp. 282-296
    • Kissoon, N1    Duckworth, L2    Blake, K3
  • 89
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • P Kubes M Suzuki DN Granger Nitric oxide: An endogenous modulator of leukocyte adhesion Proc Natl Acad Sci U S A 88 1991 4651 4655
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 4651-4655
    • Kubes, P1    Suzuki, M2    Granger, DN3
  • 90
    • 0038806343 scopus 로고    scopus 로고
    • Inhaled nitric oxide inhibits platelet-leukocyte interactions in patients with acute respiratory distress syndrome
    • A Gries A Herr S Kirsch Inhaled nitric oxide inhibits platelet-leukocyte interactions in patients with acute respiratory distress syndrome Crit Care Med 31 2003 1697 1704
    • (2003) Crit Care Med , vol.31 , pp. 1697-1704
    • Gries, A1    Herr, A2    Kirsch, S3
  • 91
    • 0033624253 scopus 로고    scopus 로고
    • Hypoxia/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice
    • DK Kaul RP Hebbel Hypoxia/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice J Clin Invest 106 2000 411 420
    • (2000) J Clin Invest , vol.106 , pp. 411-420
    • Kaul, DK1    Hebbel, RP2
  • 92
    • 0028021565 scopus 로고
    • Role of P-selectin in microvascular leukocyte-endothelial interaction in splanchnic ischemia-reperfusion
    • KL Davenpeck TW Gauthier KH Albertine Role of P-selectin in microvascular leukocyte-endothelial interaction in splanchnic ischemia-reperfusion Am J Physiol 267 1994 H622 H630
    • (1994) Am J Physiol , vol.267 , pp. H622-H630
    • Davenpeck, KL1    Gauthier, TW2    Albertine, KH3
  • 93
    • 0028128957 scopus 로고
    • Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation
    • KL Davenpeck TW Gauthier AM Lefer Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation Gastroenterology 107 1994 1050 1058
    • (1994) Gastroenterology , vol.107 , pp. 1050-1058
    • Davenpeck, KL1    Gauthier, TW2    Lefer, AM3
  • 94
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation: Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • R De Caterina P Libby HB Peng Nitric oxide decreases cytokine-induced endothelial activation: Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines J Clin Invest 96 1995 60 68
    • (1995) J Clin Invest , vol.96 , pp. 60-68
    • De Caterina, R1    Libby, P2    Peng, HB3
  • 95
    • 0028034751 scopus 로고
    • Nitric oxide attenuates leukocyte-endothelial interaction via P-selectin in splanchnic ischemia-reperfusion
    • TW Gauthier KL Davenpeck AM Lefer Nitric oxide attenuates leukocyte-endothelial interaction via P-selectin in splanchnic ischemia-reperfusion Am J Physiol 267 1994 G562 G568
    • (1994) Am J Physiol , vol.267 , pp. G562-G568
    • Gauthier, TW1    Davenpeck, KL2    Lefer, AM3
  • 96
    • 0029163193 scopus 로고
    • Nitric oxide protects against leukocyte-endothelium interactions in the early stages of hypercholesterolemia
    • TW Gauthier R Scalia T Murohara Nitric oxide protects against leukocyte-endothelium interactions in the early stages of hypercholesterolemia Arterioscler Thromb Vasc Biol 15 1995 1652 1659
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1652-1659
    • Gauthier, TW1    Scalia, R2    Murohara, T3
  • 97
    • 0028889646 scopus 로고
    • Exposure to shear stress alters endothelial adhesiveness: Role of nitric oxide
    • PS Tsao NP Lewis S Alpert Exposure to shear stress alters endothelial adhesiveness: Role of nitric oxide Circulation 92 1995 3513 3519
    • (1995) Circulation , vol.92 , pp. 3513-3519
    • Tsao, PS1    Lewis, NP2    Alpert, S3
  • 98
    • 0029741925 scopus 로고    scopus 로고
    • Fluid flow inhibits endothelial adhesiveness: Nitric oxide and transcriptional regulation of VCAM-1
    • PS Tsao R Buitrago JR Chan Fluid flow inhibits endothelial adhesiveness: Nitric oxide and transcriptional regulation of VCAM-1 Circulation 94 1996 1682 1689
    • (1996) Circulation , vol.94 , pp. 1682-1689
    • Tsao, PS1    Buitrago, R2    Chan, JR3
  • 99
    • 0043245821 scopus 로고    scopus 로고
    • Inhaled nitric oxide protects transgenic SAD mice from sickle cell disease-specific lung injury induced by hypoxia/reoxygenation
    • L de Franceschi A Baron A Scarpa Inhaled nitric oxide protects transgenic SAD mice from sickle cell disease-specific lung injury induced by hypoxia/reoxygenation Blood 102 2003 1087 1096
    • (2003) Blood , vol.102 , pp. 1087-1096
    • de Franceschi, L1    Baron, A2    Scarpa, A3
  • 100
    • 0024959625 scopus 로고
    • Human endothelial cells inhibit platelet aggregation by separately stimulating platelet cyclic AMP and cyclic GMP
    • U Alheid I Reichwehr U Forstermann Human endothelial cells inhibit platelet aggregation by separately stimulating platelet cyclic AMP and cyclic GMP Eur J Pharmacol 164 1989 103 110
    • (1989) Eur J Pharmacol , vol.164 , pp. 103-110
    • Alheid, U1    Reichwehr, I2    Forstermann, U3
  • 101
    • 0342601384 scopus 로고    scopus 로고
    • Inhaled nitric oxide inhibits platelet aggregation after pulmonary embolism in pigs
    • A Gries BW Bottiger J Dorsam Inhaled nitric oxide inhibits platelet aggregation after pulmonary embolism in pigs Anesthesiology 86 1997 387 393
    • (1997) Anesthesiology , vol.86 , pp. 387-393
    • Gries, A1    Bottiger, BW2    Dorsam, J3
  • 102
    • 0025357396 scopus 로고
    • Prolongation of fibrinolytic activity of tissue plasminogen activator by nitrovasodilators
    • R Korbut PS Lidbury JR Vane Prolongation of fibrinolytic activity of tissue plasminogen activator by nitrovasodilators Lancet 335 1990 669
    • (1990) Lancet , vol.335 , pp. 669
    • Korbut, R1    Lidbury, PS2    Vane, JR3
  • 103
    • 0026666810 scopus 로고
    • Antiplatelet and antithrombotic effects of organic nitrates
    • J Loscalzo Antiplatelet and antithrombotic effects of organic nitrates Am J Cardiol 70 1992 18B 22B
    • (1992) Am J Cardiol , vol.70 , pp. 18B-22B
    • Loscalzo, J1
  • 104
    • 0023928184 scopus 로고
    • Endothelium-derived relaxing factor: Identification as nitric oxide and role in the control of vascular tone and platelet function
    • S Moncada MW Radomski RM Palmer Endothelium-derived relaxing factor: Identification as nitric oxide and role in the control of vascular tone and platelet function Biochem Pharmacol 37 1988 2495 2501
    • (1988) Biochem Pharmacol , vol.37 , pp. 2495-2501
    • Moncada, S1    Radomski, MW2    Palmer, RM3
  • 105
    • 0023568115 scopus 로고
    • The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium
    • MW Radomski RM Palmer S Moncada The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium Biochem Biophys Res Commun 148 1987 1482 1489
    • (1987) Biochem Biophys Res Commun , vol.148 , pp. 1482-1489
    • Radomski, MW1    Palmer, RM2    Moncada, S3
  • 106
    • 0030032932 scopus 로고    scopus 로고
    • Enhancement of platelet deposition by cross-linked hemoglobin in a rat carotid endarterectomy model
    • S Olsen D Tang M Jackson Enhancement of platelet deposition by cross-linked hemoglobin in a rat carotid endarterectomy model Circulation 93 1996 327 332
    • (1996) Circulation , vol.93 , pp. 327-332
    • Olsen, S1    Tang, D2    Jackson, M3
  • 107
    • 11244281582 scopus 로고    scopus 로고
    • Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: In vitro inhibition of ADAMTS13 activity by hemoglobin
    • J Studt J Hovinga G Antoine Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: In vitro inhibition of ADAMTS13 activity by hemoglobin Blood 105 2005 542 544
    • (2005) Blood , vol.105 , pp. 542-544
    • Studt, J1    Hovinga, J2    Antoine, G3
  • 108
    • 0033636073 scopus 로고    scopus 로고
    • Inhibition of human platelet aggregation by a novel S-nitrosothiol is abolished by hemoglobin and red blood cells in vitro: Implications for anti-thrombotic therapy
    • I Megson N Sogo F Mazzei Inhibition of human platelet aggregation by a novel S-nitrosothiol is abolished by hemoglobin and red blood cells in vitro: Implications for anti-thrombotic therapy Br J Pharmacol 131 2000 1391 1398
    • (2000) Br J Pharmacol , vol.131 , pp. 1391-1398
    • Megson, I1    Sogo, N2    Mazzei, F3
  • 109
    • 1942470455 scopus 로고    scopus 로고
    • Rapid regulation of platelet activation in vivo by nitric oxide
    • A Schafer F Weismann S Neubauer Rapid regulation of platelet activation in vivo by nitric oxide Circulation 109 2004 1819 1822
    • (2004) Circulation , vol.109 , pp. 1819-1822
    • Schafer, A1    Weismann, F2    Neubauer, S3
  • 110
    • 0025936489 scopus 로고
    • Inhibition of human platelet reactivity by endothelium-derived relaxing factor from human umbilical vein endothelial cells in suspension: Blockade of aggregation and secretion by an aspirin insensitive mechanism
    • M Broekman A Eiroa A Marcus Inhibition of human platelet reactivity by endothelium-derived relaxing factor from human umbilical vein endothelial cells in suspension: Blockade of aggregation and secretion by an aspirin insensitive mechanism Blood 78 1991 1033 1040
    • (1991) Blood , vol.78 , pp. 1033-1040
    • Broekman, M1    Eiroa, A2    Marcus, A3
  • 111
    • 0032504540 scopus 로고    scopus 로고
    • Inhibition of clotting factor XIII activity by nitric oxide
    • M Catani F Bernassola A Rossi Inhibition of clotting factor XIII activity by nitric oxide Biochem Biophys Res Commun 249 1998 275 278
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 275-278
    • Catani, M1    Bernassola, F2    Rossi, A3
  • 112
    • 0034836577 scopus 로고    scopus 로고
    • Protective role of nitric oxide in a model of thrombotic microangiopathy in rats
    • J Shao T Miyata K Yamada Protective role of nitric oxide in a model of thrombotic microangiopathy in rats J Am Soc Nephrol 12 2001 2088 2097
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2088-2097
    • Shao, J1    Miyata, T2    Yamada, K3
  • 113
    • 0032845362 scopus 로고    scopus 로고
    • Reduced nitric oxide production by L-arginine deficiency in lysinuric protein intolerance exacerbates intravascular coagulation
    • Y Kayanoki S Kawata E Yamasaki Reduced nitric oxide production by L-arginine deficiency in lysinuric protein intolerance exacerbates intravascular coagulation Metabolism 48 1999 1136 1140
    • (1999) Metabolism , vol.48 , pp. 1136-1140
    • Kayanoki, Y1    Kawata, S2    Yamasaki, E3
  • 114
    • 0001229128 scopus 로고
    • Effect of cationic amino acid infusion on potassium metabolism in vivo
    • HW Dickerman WG Walker Effect of cationic amino acid infusion on potassium metabolism in vivo Am J Physiol 206 1964 403 408
    • (1964) Am J Physiol , vol.206 , pp. 403-408
    • Dickerman, HW1    Walker, WG2
  • 115
    • 0016074208 scopus 로고
    • Two new antisickling agents and the use of amino acid salts
    • AJ Sophianopoulos JA Sophianopoulos OC Grush Two new antisickling agents and the use of amino acid salts Clin Biochem 7 1974 112 118
    • (1974) Clin Biochem , vol.7 , pp. 112-118
    • Sophianopoulos, AJ1    Sophianopoulos, JA2    Grush, OC3
  • 116
    • 0025598375 scopus 로고
    • Nitrogen metabolism in sickle cell anemia: free amino acids in plasma and urine
    • CO Enwonwu XX Xu E Turner Nitrogen metabolism in sickle cell anemia: free amino acids in plasma and urine Am J Med Sci 300 1990 366 371
    • (1990) Am J Med Sci , vol.300 , pp. 366-371
    • Enwonwu, CO1    Xu, XX2    Turner, E3
  • 117
    • 0021833886 scopus 로고
    • Growth retardation in sickle-cell disease treated by nutritional support
    • MB Heyman E Vichinsky R Katz Growth retardation in sickle-cell disease treated by nutritional support Lancet 1 1985 903 906
    • (1985) Lancet , vol.1 , pp. 903-906
    • Heyman, MB1    Vichinsky, E2    Katz, R3
  • 118
    • 0027202636 scopus 로고
    • Inhibition of endothelium-dependent vasorelaxation by sickle erythrocytes
    • M Mosseri AN Bartlett-Pandite K Wenc Inhibition of endothelium-dependent vasorelaxation by sickle erythrocytes Am Heart J 126 1993 338 346
    • (1993) Am Heart J , vol.126 , pp. 338-346
    • Mosseri, M1    Bartlett-Pandite, AN2    Wenc, K3
  • 119
    • 0030912619 scopus 로고    scopus 로고
    • Mechanisms of stroke in sickle cell disease: sickle erythrocytes decrease cerebral blood flow in rats after nitric oxide synthase inhibition
    • JA French II D Kenny JP Scott Mechanisms of stroke in sickle cell disease: sickle erythrocytes decrease cerebral blood flow in rats after nitric oxide synthase inhibition Blood 89 1997 4591 4599
    • (1997) Blood , vol.89 , pp. 4591-4599
    • French, JA1    Kenny, D2    Scott, JP3
  • 120
    • 0032718353 scopus 로고    scopus 로고
    • Endothelial cell nitric oxide production in acute chest syndrome
    • SI Hammerman ES Klings KP Hendra Endothelial cell nitric oxide production in acute chest syndrome Am J Physiol 277 1999 H1579 H1592
    • (1999) Am J Physiol , vol.277 , pp. H1579-H1592
    • Hammerman, SI1    Klings, ES2    Hendra, KP3
  • 121
    • 0028801145 scopus 로고
    • The metabolites of nitric oxide in sickle-cell disease
    • DC Rees P Cervi D Grimwade The metabolites of nitric oxide in sickle-cell disease Br J Haematol 91 1995 834 837
    • (1995) Br J Haematol , vol.91 , pp. 834-837
    • Rees, DC1    Cervi, P2    Grimwade, D3
  • 122
    • 0029853004 scopus 로고    scopus 로고
    • Nitric oxide metabolite levels in acute vaso-occlusive sickle-cell crisis
    • BL Lopez J Barnett SK Ballas Nitric oxide metabolite levels in acute vaso-occlusive sickle-cell crisis Acad Emerg Med 3 1996 1098 1103
    • (1996) Acad Emerg Med , vol.3 , pp. 1098-1103
    • Lopez, BL1    Barnett, J2    Ballas, SK3
  • 123
    • 0037323910 scopus 로고    scopus 로고
    • L-arginine levels are diminished in adult acute vaso-occlusive sickle cell crisis in the emergency department
    • BL Lopez AA Kreshak CR Morris L-arginine levels are diminished in adult acute vaso-occlusive sickle cell crisis in the emergency department Br J Haematol 120 2003 532 534
    • (2003) Br J Haematol , vol.120 , pp. 532-534
    • Lopez, BL1    Kreshak, AA2    Morris, CR3
  • 124
    • 0034321784 scopus 로고    scopus 로고
    • Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome
    • CR Morris FA Kuypers S Larkin Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome J Pediatr Hematol Oncol 22 2000 515 520
    • (2000) J Pediatr Hematol Oncol , vol.22 , pp. 515-520
    • Morris, CR1    Kuypers, FA2    Larkin, S3
  • 125
    • 0034533319 scopus 로고    scopus 로고
    • Arginine therapy: A novel strategy to induce nitric oxide production in sickle cell disease
    • CR Morris FA Kuypers S Larkin Arginine therapy: A novel strategy to induce nitric oxide production in sickle cell disease Br J Haematol 111 2000 498 500
    • (2000) Br J Haematol , vol.111 , pp. 498-500
    • Morris, CR1    Kuypers, FA2    Larkin, S3
  • 126
    • 0029070801 scopus 로고
    • Interactions between L-arginine and L-glutamine change endothelial NO production: An effect independent of NO synthase substrate availability
    • JF Arnal T Munzel RC Venema Interactions between L-arginine and L-glutamine change endothelial NO production: An effect independent of NO synthase substrate availability J Clin Invest 95 1995 2565 2572
    • (1995) J Clin Invest , vol.95 , pp. 2565-2572
    • Arnal, JF1    Munzel, T2    Venema, RC3
  • 127
    • 0026459857 scopus 로고
    • L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans
    • MA Creager SJ Gallagher XJ Girerd L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans J Clin Invest 90 1992 1248 1253
    • (1992) J Clin Invest , vol.90 , pp. 1248-1253
    • Creager, MA1    Gallagher, SJ2    Girerd, XJ3
  • 128
    • 0029670349 scopus 로고    scopus 로고
    • Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits
    • SM Bode-Boger RH Boger S Kienke Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits Biochem Biophys Res Commun 219 1996 598 603
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 598-603
    • Bode-Boger, SM1    Boger, RH2    Kienke, S3
  • 129
    • 0031452440 scopus 로고    scopus 로고
    • A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the “arginine paradox.”
    • KK McDonald S Zharikov ER Block A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric-oxide synthase may explain the “arginine paradox.” J Biol Chem 272 1997 31213 31216
    • (1997) J Biol Chem , vol.272 , pp. 31213-31216
    • McDonald, KK1    Zharikov, S2    Block, ER3
  • 130
    • 0035708575 scopus 로고    scopus 로고
    • Caveolar localization of arginine regeneration enzymes, argininosuccinate synthase, and lyase, with endothelial nitric oxide synthase
    • BR Flam PJ Hartmann M Harrell-Booth Caveolar localization of arginine regeneration enzymes, argininosuccinate synthase, and lyase, with endothelial nitric oxide synthase Nitric Oxide 5 2001 187 197
    • (2001) Nitric Oxide , vol.5 , pp. 187-197
    • Flam, BR1    Hartmann, PJ2    Harrell-Booth, M3
  • 131
    • 0035490032 scopus 로고    scopus 로고
    • Oral citrulline as arginine precursor may be beneficial in sickle cell disease: Early phase two results
    • WH Waugh CW Daeschner III BA Files Oral citrulline as arginine precursor may be beneficial in sickle cell disease: Early phase two results J Natl Med Assoc 93 2001 363 371
    • (2001) J Natl Med Assoc , vol.93 , pp. 363-371
    • Waugh, WH1    Daeschner, CW2    Files, BA3
  • 132
    • 21444441271 scopus 로고    scopus 로고
    • Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease
    • CR Morris GJ Kato M Poljakovic Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease JAMA 294 2005 81 90
    • (2005) JAMA , vol.294 , pp. 81-90
    • Morris, CR1    Kato, GJ2    Poljakovic, M3
  • 133
    • 0036908599 scopus 로고    scopus 로고
    • Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
    • CD Reiter X Wang JE Tanus-Santos Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease Nat Med 8 2002 1383 1389
    • (2002) Nat Med , vol.8 , pp. 1383-1389
    • Reiter, CD1    Wang, X2    Tanus-Santos, JE3
  • 134
    • 0032189829 scopus 로고    scopus 로고
    • Increased levels of endothelin-1 in plasma of sickle cell anemia patients
    • AC Rybicki LJ Benjamin Increased levels of endothelin-1 in plasma of sickle cell anemia patients Blood 92 1998 2594 2596
    • (1998) Blood , vol.92 , pp. 2594-2596
    • Rybicki, AC1    Benjamin, LJ2
  • 135
    • 0034804353 scopus 로고    scopus 로고
    • Hemoglobin increases endothelin-1 in endothelial cells by decreasing nitric oxide
    • G Lin RL Macdonald LS Marton Hemoglobin increases endothelin-1 in endothelial cells by decreasing nitric oxide Biochem Biophys Res Commun 280 2001 824 830
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 824-830
    • Lin, G1    Macdonald, RL2    Marton, LS3
  • 136
    • 1642458091 scopus 로고    scopus 로고
    • Association of T-786C eNOS gene polymorphism with increased susceptibility to acute chest syndrome in females with sickle cell disease
    • K Sharan S Surrey S Ballas Association of T-786C eNOS gene polymorphism with increased susceptibility to acute chest syndrome in females with sickle cell disease Br J Haematol 124 2004 240 243
    • (2004) Br J Haematol , vol.124 , pp. 240-243
    • Sharan, K1    Surrey, S2    Ballas, S3
  • 137
    • 33748780631 scopus 로고    scopus 로고
    • ET-1 and ecNOS gene polymorphisms and susceptibility to acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia
    • V Chaar V Tarer M Etienne-Julan ET-1 and ecNOS gene polymorphisms and susceptibility to acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia Haematologica 91 2006 1277 1278
    • (2006) Haematologica , vol.91 , pp. 1277-1278
    • Chaar, V1    Tarer, V2    Etienne-Julan, M3
  • 138
    • 0030714983 scopus 로고    scopus 로고
    • Decreased nitric oxide in the exhaled air of patients with systemic sclerosis with pulmonary hypertension
    • SA Kharitonov JB Cailes CM Black Decreased nitric oxide in the exhaled air of patients with systemic sclerosis with pulmonary hypertension Thorax 52 1997 1051 1055
    • (1997) Thorax , vol.52 , pp. 1051-1055
    • Kharitonov, SA1    Cailes, JB2    Black, CM3
  • 139
    • 0032211192 scopus 로고    scopus 로고
    • Beneficial effect of intravenous dexamethasone in children with mild to moderately severe acute chest syndrome complicating sickle cell disease
    • JC Bernini ZR Rogers ES Sandler Beneficial effect of intravenous dexamethasone in children with mild to moderately severe acute chest syndrome complicating sickle cell disease Blood 92 1998 3082 3089
    • (1998) Blood , vol.92 , pp. 3082-3089
    • Bernini, JC1    Rogers, ZR2    Sandler, ES3
  • 140
    • 0025045540 scopus 로고
    • Planning an exchange transfusion in patients with sickle cell syndromes
    • S Piomelli C Seaman K Ackerman Planning an exchange transfusion in patients with sickle cell syndromes Am J Pediatr Hematol Oncol 12 1990 268 276
    • (1990) Am J Pediatr Hematol Oncol , vol.12 , pp. 268-276
    • Piomelli, S1    Seaman, C2    Ackerman, K3
  • 141
    • 0030669447 scopus 로고    scopus 로고
    • Inhaled nitric oxide in sickle cell disease with acute chest syndrome
    • AM Atz DL Wessel Inhaled nitric oxide in sickle cell disease with acute chest syndrome Anesthesiology 87 1997 988 990
    • (1997) Anesthesiology , vol.87 , pp. 988-990
    • Atz, AM1    Wessel, DL2
  • 142
    • 0032738619 scopus 로고    scopus 로고
    • Nitric oxide successfully used to treat acute chest syndrome of sickle cell disease in a young adolescent
    • KJ Sullivan SR Goodwin J Evangelist Nitric oxide successfully used to treat acute chest syndrome of sickle cell disease in a young adolescent Crit Care Med 27 1999 2563 2568
    • (1999) Crit Care Med , vol.27 , pp. 2563-2568
    • Sullivan, KJ1    Goodwin, SR2    Evangelist, J3
  • 143
    • 0031424558 scopus 로고    scopus 로고
    • Successful treatment of life-threatening acute chest syndrome of sickle cell disease with venovenous extracorporeal membrane oxygenation
    • MA Pelidis GJ Kato LM Resar Successful treatment of life-threatening acute chest syndrome of sickle cell disease with venovenous extracorporeal membrane oxygenation J Pediatr Hematol Oncol 19 1997 459 461
    • (1997) J Pediatr Hematol Oncol , vol.19 , pp. 459-461
    • Pelidis, MA1    Kato, GJ2    Resar, LM3
  • 144
    • 0043204998 scopus 로고    scopus 로고
    • Arginine therapy: A new treatment for pulmonary hypertension in sickle cell disease?
    • CR Morris SM Morris Jr W Hagar Arginine therapy: A new treatment for pulmonary hypertension in sickle cell disease? Am J Respir Crit Care Med 168 2003 63 69
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 63-69
    • Morris, CR1    Morris, SM2    Hagar, W3
  • 145
    • 0037420269 scopus 로고    scopus 로고
    • Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease
    • DL Weiner PL Hibberd P Betit Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease JAMA 289 2003 1136 1142
    • (2003) JAMA , vol.289 , pp. 1136-1142
    • Weiner, DL1    Hibberd, PL2    Betit, P3


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