Low concentrations of nitric oxide increase oxygen affinity of sickle erythrocytes in vitro and in vivo

Journal of Clinical Investigation

Volumn 100, Issue 5, 1997, Pages 1193-1198

  Head, C Alvin ^a   Brugnara, Carlo ^b   Martinez Ruiz, Ricardo ^a   Kacmarek, Robert M ^a   Bridges, Kenneth R ^c   Kuter, David ^a   Bloch, Kenneth D ^a   Zapol, Warren M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Anemia; Antisickling agents; P50; Therapy

Indexed keywords

HEMOGLOBIN; HEMOGLOBIN S; METHEMOGLOBIN; NITRIC OXIDE; OXYGEN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; OXYGEN AFFINITY; OXYGEN DISSOCIATION CURVE; OXYGEN SATURATION; PRIORITY JOURNAL; SICKLE CELL; SICKLE CELL ANEMIA;

EID: 0030982523     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119631     Document Type: Article

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