Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory

Nature Immunology

Volumn 3, Issue 2, 2002, Pages 182-188

  Martin, Stephen W ^a   Goodnow, Christopher C ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CELL COUNT; CONTROLLED STUDY; IMMUNOLOGICAL MEMORY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY AFFINITY; ANTIBODY FORMATION; B-LYMPHOCYTES; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN ISOTYPES; IMMUNOGLOBULIN M; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MURAMIDASE; RECEPTORS, ANTIGEN, B-CELL; SPLEEN;

EID: 0036171910     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni752     Document Type: Article

References (42)

1. Primary and specific anamnestic antibody responses of rabbits to heterologous serum protein antigens
2. Immunological memory and protective immunity: Understanding their relation
3. The cellular basis of immunologic memory
4. Immunological memory
5. T & B memory cells
6. Isolation of high-affinity memory B cells: Phycoerythrin as a probe for antigen-binding cells
7. Maintenance of B-cell memory by long-lived cells generated from proliferating precursors
8. Variations in affinities of antibodies during the immune response
9. The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response
10. + peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells
11. Identification of functional human splenic memory B cells by expression of CD148 and CD27
12. Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2
13. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
14. Marginal-zone B cells in the human lymph node and spleen show somatic hypermutations and display clonal expansion
15. Memory B cell persistence is independent of persisting immunizing antigen
16. Antigen receptors on B lymphocytes
17. Immune responses: Tails to teach a B cell
18. The internalization of the IgG2a antigen receptor does not require the association with Ig-α and Ig-β but the activation of protein tyrosine kinases does
19. Antigen endocytosis and presentation mediated by human membrane IgGI in the absence of the Igα/Igβ dimer
20. The roles of gamma I heavy chain membrane expression and cytoplasmic tail in IgGI responses
21. Effect of transmembrane and cytoplasmic domains of IgE on the IgE response
22. Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen
23. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
24. Gene dose-dependent maturation and receptor editing of B cells expressing immunoglobulin (Ig)GI or IgM/IgGI tail antigen receptors
25. + T cells
26. Ig heavy chain extracellular spacer confers unique glycosylation of the Mb-1 component of the B cell antigen receptor complex
27. Determination of lymphocyte division by flow cytometry
28. Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival
29. The clonal selection theory of acquired immunity
30. The class of surface immunoglobulin on virgin and memory B lymphocytes
31. Cell surface immunoglobulin. XX. Antibody responsiveness of subpopulations of B lymphocytes bearing different isotypes
32. In vitro activation of murine antigen-specific memory B cells by a T-dependent antigen
33. Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation
34. A periarteriolar lymphoid sheath-associated B cell focus response is not observed during the development of the anti-arsonate germinal center reaction
35. Memory B cells are biased towards terminal differentiation: A strategy that may prevent repertoire freezing
36. Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells
37. Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: Effect or function is linked to proliferative capacity
38. Fine specificity of the H-2 linked immune response gene for the gallinaceous lysozymes
39. Using carboxyfluorescein diacetate succinimidyl ester to monitor human NK cell division: Analysis of the effect of activating and inhibitory class 1 MHC receptors
40. Effects of the lpr mutation on elimination and inactivation of self-reactive B cells
41. Induction of self-tolerance in mature peripheral B lymphocytes
42. Development and follicular localization of tolerant B lymphocytes in lysozyme/anti-lysozyme IgM/IgD transgenic mice