Identification of functional human splenic memory B cells by expression of CD148 and CD27

Journal of Experimental Medicine

Volumn 188, Issue 9, 1998, Pages 1691-1703

  Tangye, Stuart G ^a   Liu, Yong Jun ^a   Aversa, Gregorio ^a,b   Phillips, Joseph H ^a   De Vries, Jan E ^a,b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NOVARTIS RESEARCH INSTITUTE   (Austria)

Author keywords

CD148; CD27; Human memory B cells; Marginal zone B cells; Somatic mutation

Indexed keywords

CD27 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MONOCLONAL ANTIBODY;

ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN VARIABLE REGION; MEMORY CELL; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SOMATIC MUTATION; SPLEEN CELL; TONSIL;

ANTIGENS, CD27; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; BASE SEQUENCE; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; DNA PRIMERS; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGIC MEMORY; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN-TYROSINE-PHOSPHATASE; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPLEEN;

EID: 0032476617     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.9.1691     Document Type: Article

References (54)

1. MacLennan, I.C., Y.-J. Liu, and G.D. Johnson. 1992. Maturation and dispersal of B-cell clones during T cell-dependent antibody responses. Immunol. Rev. 126:143-161.
2. Banchereau, J., and F. Rousset. 1992. Human B lymphocytes: phenotype, proliferation, and differentiation. Adv. Immunol. 52:125-262.
3. Gray, D. 1993. Immunological memory. Annu. Rev. Immunol. 11:49-77.
4. Rajewsky, K. 1996. Clonal selection and learning in the antibody system. Nature. 381:751-758.
5. Liu, Y.-J., G. Grouard, O. de Bouteiller, and J. Banchereau. 1996. Follicular dendritic cells and germinal centers. Int. Rev. Cytol. 166:139-179.
6. Liu, Y.-J., and J. Banchereau. 1996. The paths and molecular controls of peripheral B-cell development. The Immunologist. 4:55-66.
7. MacLennan, I.C. 1994. Germinal centers. Annu. Rev. Immunol. 12:117-139.
8. Thorbecke, G.J., A.R. Amin, and V.K. Tsiagbe. 1994. Biology of germinal centers in lymphoid tissue. FASEB J. 8:832-840.
9. Han, S., B. Zheng, Y. Takahashi, and G. Kelsoe. 1997. Distinctive characteristics of germinal center B cells. Semin. Immunol. 9:255-260.
10. Liu, Y.-J., and C. Arpin. 1997. Germinal center development. Immunol. Rev. 156:111-126.
11. Liu, Y.-J., D.E. Joshua, G.T. Williams, C.A. Smith, J. Gordon, and I.C. MacLennan. 1989. Mechanisms of antigen-driven selection in germinal centres. Nature. 342:929-931.
12. Küppers, R., M. Zhao, M.L. Hansmann, and K. Rajewsky. 1993. Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. EMBO J. 12:4955-4967.
13. Liu, Y.-J., F. Malisan, O. de Bouteiller, C. Guret, S. Lebecque, J. Banchereau, F.C. Mills, E.E. Max, and H. Martinez-Valdez. 1996. Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation. Immunity. 4:241-250.
14. Liu, Y.-J., C. Arpin, O. de Bouteiller, C. Guret, J. Banchereau, H. Martinez-Valdez, and S. Lebecque. 1996. Sequential triggering of apoptosis, somatic mutation and isotype switch during germinal center development. Semin. Immunol. 8:169-177.
15. Pascual, V., Y.-J. Liu, A. Magalski, O. de Bouteiller, J. Banchereau, and J.D. Capra. 1994. Analysis of somatic mutation in five B cell subsets of human tonsil. J. Exp. Med. 180: 329-339.
16. Liu, Y.-J., C. Barthelemy, O. de Bouteiller, C. Arpin, I. Durand, and J. Banchereau. 1995. Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2. Immunity. 2:239-248.
17. + B cells, the major B cell subset in the peripheral blood, express Vκ genes with no or little somatic mutation throughout life. Eur. J. Immunol. 23:3272-3277.
18. Paramithiotis, E., and M.D. Cooper. 1997. Memory B lymphocytes migrate to bone marrow in humans. Proc. Natl. Acad. Sci. USA. 94:208-212.
19. Klein, U., R. Küppers, and K. Rajewsky. 1997. Evidence for a large compartment of IgM-expressing memory B cells in humans. Blood. 89:1288-1298.
20. Klein, U., T. Goossens, M. Fischer, H. Kanzler, A. Braeuninger, K. Rajewsky, and R. Küppers. 1998. Somatic hypermutation in normal and transformed human B cells. Immunol. Rev. 162:261-280.
21. Timens, W.M., and S. Poppema. 1985. Lymphocyte compartments in human spleen. An immunohistologic study in normal spleens and noninvolved spleens in Hodgkin's disease. Am J. Pathol. 120:443-454.
22. Timens, W., A. Boes, and S. Poppema. 1989. Human marginal zone B cells are not an activated B cell subset: strong expression of CD21 as a putative mediator for rapid B cell activation. Immunology. 19:2163-2166.
23. Smith-Ravin, J., J. Spencer, P.C.L. Beverley, and P.G. Isaacson. 1990. Characterization of two monoclonal antibodies (UCL4D12 and UCL3D3) that discriminate between human mantle zone and marginal zone B cells. Clin. Exp. Immunol. 82:181-187.
24. Kraal, G. 1992. Cells in the marginal zone of the spleen. Int. Rev. Cytol. 132:31-74.
25. Dunn-Walters, D.K., P.G. Isaacson, and J. Spencer. 1995. Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells. J. Exp. Med. 182:559-566.
26. Liu, Y.-J., S. Oldfield, and I.C. MacLennan. 1988. Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones. Eur. J. Immunol. 18:355-362.
27. - germinal center B cells can express up to 80 mutations in the variable region of their IgD transcripts. Immunity. 4:603-613.
28. Tangye, S.G., J.H. Phillips, L.L. Lanier, J.E. de Vries, and G. Aversa. 1998. CD148: a receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation. J. Immunol. 161:3249-3255.
29. Valle, A., C.E. Zuber, T. Defrance, O. Djossou, M. de Rie, and J. Banchereau. 1989. Activation of human B lymphocytes through CD40 and interleukin-4. Eur.J. Immunol. 19: 1463-1467.
30. Aversa, G., C.C. Chang, J.M. Carballido, B.G. Cocks, and J.E. de Vries. 1997. Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production. J. Immunol. 158:4036-4044.
31. Cifone, M.G., R. De Maria, P. Roncaioli, M.R. Rippo, M. Azuma, L.L. Lanier, A. Santoni, and R. Testi. 1994. Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J. Exp. Med. 180:1547-1552.
32. Campbell, M.J., A.D. Zelenetz, S. Levy, and R. Levy. 1992. Use of family specific leader region primers for PCR amplification of the human heavy chain variable region gene repertoire. Mol. Immunol. 29:193-203.
33. + T cells expressing T cell receptor (TcR) αβ or TcR γδ induce IgE synthesis by human B cells in the presence of interleukin-4. Eur. J. Immunol. 22:1133-1141.
34. + human fetal B cells. J. Immunol. 148:3398-3404.
35. Arpin, C., J. Dechanet, C. Van Kooten, P. Merville, G. Grouard, F. Briere, J. Banchereau, and Y.-J. Liu. 1995. Generation of memory B cells and plasma cells in vitro. Science. 268:720-722.
36. Yssel, H., J.E. de Vries, M. Koken, W. van Blitterswijk, and H. Spits. 1984. Serum-free medium for the generation and propagation of functional human cytotoxic and helper T cell clones. J. Immunol. Methods. 72:219-227.
37. MacLennan, I.C.M., P.D. Nathan, G.D. Johnson, M. Khan, L. Walker, and N.R. Ling. 1986. Analysis of B and L workshop antibodies on sections of normal and neoplastic lymphoid tissue and cell lines. In Leukocyte Typing II, Vol. 2: Human B Lymphocytes. E.L. Reinherz, B.F. Haynes, L.M. Nadler, and I.D. Bernstein, editors. Springer-Verlag, New York. 257-275.
38. Hintzen, R.Q., R. de Jong, S.M. Lens, and R.A. van Lier. 1994. CD27: marker and mediator of T-cell activation? Immunol. Today. 15:307-311.
39. van Oers, M.H., S.T. Pals, L.M. Evers, C.E. van der Schoot, G. Koopman, J.M. Bonfrer, R.Q. Hintzen, A.E. von dem Borne, and R.A. van Lier. 1993. Expression and release of CD27 in human B-cell malignancies. Blood. 82:3430-3436.
40. Tomlinson, I.M., G. Walter, J.D. Marks, M.B. Llewelyn, and G. Winter. 1992. The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol. 227:776-798.
41. Arpin, C., J. Banchereau, and Y.-J. Liu. 1997. Memory B cells are biased towards terminal differentiation: a strategy that may prevent repertoire freezing. J. Exp. Med. 186:931-940.
42. Rousset, F., E. Garcia, and J. Banchereau. 1991. Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen. J. Exp. Med. 173:705-710.
43. Hodgkin, P.D., N.F. Go, J.E. Cupp, and M. Howard. 1991. Interleukin-4 enhances anti-IgM stimulation of B cells by improving cell viability and by increasing the sensitivity of B cells to the anti-IgM signal. Cell. Immunol. 134:14-30.
44. Azuma, M., D. Ito, H. Yagita, K. Okumura, J.H. Phillips, L.L. Lanier, and C. Somoza. 1993. B70 antigen is a second ligand for CTLA-4 and CD28. Nature. 366:76-79.
45. Lenschow, D.J., A.I. Sperling, M.P. Cooke, G. Freeman, L. Rhee, D.C. Decker, G. Gray, L.M. Nadler, C.C. Goodnow, and J.A. Bluestone. 1994. Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen. J. Immunol. 153:1990-1997.
46. Garrone, P., E.M. Neidhardt, E. Garcia, L. Galibert, C. van Kooten, and J. Banchereau. 1995. Fas ligation induces apoptosis of CD40-activated human B lymphocytes. J. Exp. Med. 182:1265-1273.
47. Punnonen, J., B.G. Cocks, J.M. Carballido, B. Bennett, D. Peterson, G. Aversa, and J.E. de Vries. 1997. Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes. J. Exp. Med. 185:993-1004.
48. Maurer, D., W. Holter, O. Majdic, G.F. Fischer, and W. Knapp. 1990. CD27 expression by a distinct subpopulation of human B lymphocytes. Eur. J. Immunol. 20:2679-2684.
49. + B cells and helper T cells in immunoglobulin production. Eur. J. Immunol. 27:2073-2079.
50. Agematsu, K., H. Nagumo, Y. Oguchi, T. Nakazawa, K. Fukushima, K. Yasui, S. Ito, T. Kobata, C. Morimoto, and A. Komiyama. 1998. Generation of plasma cells from peripheral blood memory B cells: synergistic effect of interleukin-10 and CD27/CD70 interaction. Blood. 91:173-180.
51. Pene, J., F. Rousset, F. Briere, I. Chreitien, J. Wideman, J.Y. Bonnefoy, and J.E. de Vries. 1988. Interleukin 5 enhances interleukin 4-induced IgE production by normal human B cells: the role of soluble CD23 antigen. Eur. J. Immunol. 18: 929-935.
52. Bonnefoy, J.Y., J.F. Gauchat, P. Life, P. Graber, G. Mazzei, and J.P. Aubry. 1996. Pairs of surface molecules involved in human IgE regulation: CD23-CD21 and CD40-CD40L. Eur. Respir. J. 22:63S-66S.
53. Cocks, B.G., R. de Waal Malefyt, J.-P. Galizzi, J.E. de Vries, and G. Aversa. 1993. IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand. Int. Immunol. 5:657-663.
54. Jacquot, S., T. Kobata, S. Iwata, C. Morimoto, and S.F. Schlossman. 1997. CD154/CD40 and CD70/CD27 interactions have different and sequential functions in T cell-dependent B cell responses: enhancement of plasma cell differentiation by CD27 signaling. J. Immunol. 159:2652-2657.