Delayed and deficient establishment of the long-term bone marrow plasma cell pool during early life

European Journal of Immunology

Volumn 31, Issue 3, 2001, Pages 939-946

  Pihlgren, Maria ^a,b   Schallert, Nadine ^a   Tougne, Chantal ^a   Bozzotti, Paola ^a   Kovarik, Jiri ^a   Fulurija, Alma ^a   Kosco Vilbois, Marie ^a   Lambert, Paul Henri ^a   Siegrist, Claire Anne ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

Author keywords

Antibody; B lymphocyte; Bone marrow; Homing; Vaccination

Indexed keywords

IMMUNOGLOBULIN G; TETANUS TOXOID;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL COUNT; CELL TRANSFER; CONTROLLED STUDY; IMMUNIZATION; IMMUNOGLOBULIN PRODUCING CELL; LYMPHOCYTE HOMING; MOUSE; MOUSE STRAIN; NEWBORN; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; RECIPIENT; SPLEEN; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; ANIMALS, NEWBORN; BONE MARROW CELLS; CELL MOVEMENT; FEMALE; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PLASMA CELLS; SPLEEN; TETANUS TOXOID; TIME FACTORS;

EID: 0035080069     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200103)31:3<939::AID-IMMU939>3.0.CO;2-I     Document Type: Article

References (31)

1. Age related IgG subclass response to respiratory syncytial virus fusion protein in infected infants
2. Immunogenicity of combined diphtheria, tetanus, and pertussis vaccine given at 2, 3, and 4 months versus 3, 5, and 9 months of age
3. Deficiency of the humoral immune response to measles vaccine in infants immunized at age 6 months
4. Developmental immunology and role of host defenses in neonatal susceptibility to infection
5. Vaccination in the neonatal period and early infancy
6. Antibody responses and persistence in the two years after immunization with two acellular vaccines and one whole-cell vaccine against pertussis
7. Diphtheria antitoxin response to DTP vaccines used in Swedish pertussis vaccine trials, persistence and projection for timing of booster
8. Effect of subclinical infection on maintaining immunity against measles in vaccinated children in West Africa
9. Secondary measles vaccine failures identified by measurement of IgG avidity: High occurrence among teenagers vaccinated at a young age
10. Lifetime of plasma cells in the bone marrow
11. Humoral immunity due to long-lived plasma cells
12. Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: Predominance of a Th2-biased pattern which persists after adult boosting
13. The bone marrow: The major source of serum immunoglobulins, but still a neglected site of antibody formation
14. Frequencies of background immunoglobulin-secreting cells in mice as a function if organ, age, and immune status
15. The dynamic structure of the germinal center
16. B lymphocyte migration to the bone marrow of humans is not random
17. bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells
18. Age-dependent changes in the relative affinity of anti-dinitrophenyl antibodies in mice
19. Ontogeny of murine-B-lymphocytes. Avidity of antigen binding cells in neonatal and adult mice
20. Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice
21. Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins
22. The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
23. Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice
24. Germinal center B cells and antibody production in the bone marrow
25. Molecular basis of homing of intravenously transplanted stem cells to the marrow
26. Key differentiation steps in normal B cells and in myeloma cells
27. Characterization of VLA-4-dependent myeloma cell adhesion to fibronectin and VCAM-1
28. Adhesion receptors on bone marrow stromal cells: In vivo expression of vascular cell adhesion molecule-1 by reticular cells and sinusoidal endothelium in normal and gamma-irradiated mice
29. Bone marrow is a major site of long-term antibody production after acute viral infection
30. Quantitative studies of blood and bone marrow neutrophils in normal mice
31. Induction of antibody formation in mouse bone marrow