CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations

Journal of Leukocyte Biology

Volumn 75, Issue 6, 2004, Pages 1022-1028

  Arce, Sergio ^a   Luger, Elke ^a   Muehlinghaus, Gwendolin ^a   Cassese, Giuliana ^a   Hauser, Anja ^a   Horst, Alexander ^b   Lehnert, Katja ^a   Odendahl, Marcus ^a   Hönemann, Dirk ^c   Heller, Karl Dieter ^d   Kleinschmidt, Harald ^d   Berek, Claudia ^a   Dörner, Thomas ^c   Krenn, Veit ^c   Hiepe, Falk ^c   Bargou, Ralf ^c   Radbruch, Andreas ^a   Manz, Rudolf A ^a  

^a DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^b MILTENYI BIOTEC GMBH   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d KLINIKUM BRAUNSCHWEIG   (Germany)

Author keywords

Antibodies; B lymphocytes; Cellular differentiation; Memory

Indexed keywords

CD19 ANTIGEN; CD38 ANTIGEN; CD9 ANTIGEN; IMMUNOGLOBULIN G;

ARTICLE; BONE MARROW; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL ISOLATION; CONTROLLED STUDY; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; IMMUNOLOGICAL MEMORY; PLASMA CELL; PRIORITY JOURNAL; TONSIL;

ADP-RIBOSYL CYCLASE; ANTIGENS, CD; ANTIGENS, CD19; ANTIGENS, CD38; B-LYMPHOCYTE SUBSETS; BONE MARROW; CELL DIFFERENTIATION; CELL MOVEMENT; HUMANS; IMMUNOGLOBULIN G; MEMBRANE GLYCOPROTEINS; PHENOTYPE; PLASMA CELLS; TONSIL;

EID: 2642554833     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0603279     Document Type: Article

References (39)

1. Hargreaves, D. C., Hyman, P. L., Lu, T. T., Ngo, V. N., Bidgol, A., Suzuki, G., Zou, Y. R., Littman, D. R., Cyster, J. G. (2001) A coordinated change in chemokine responsiveness guides plasma cell movements. J. Exp. Med. 194, 45-56.
2. Hauser, A. E., Debes, G. F., Arce, S., Cassese, G., Hamann, A., Radbruch, A., Manz, R. A. (2002) Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response. J. Immunol. 169, 1277-1282.
3. Benner, R., Hijmans, W., Haaijman, J. J. (1981) The bone marrow: the major source of serum immunoglobulins, but still a neglected site of antibody formation. Clin. Exp. Immunol. 46, 1-8.
4. Cassese, G., Lindenau, S., de Boer, B., Arce, S., Hauser, A., Riemekasten, G., Berek, C., Hiepe, F., Krenn, V., Radbruch, A., Manz, R. A. (2001) Inflamed kidneys of NZB/W mice are a major site for the homeostasis of plasma cells. Eur. J. Immunol. 31, 2726-2732.
5. Manz, R. A., Thiel, A., Radbruch, A. (1997) Lifetime of plasma cells in the bone marrow. Nature 388, 133-134.
6. Slifka, M. K., Antia, R., Whitmire, J. K., Ahmed, R. (1998) Humoral immunity due to long-lived plasma cells. Immunity 8, 363-372.
7. Arpin, C., Dechanet, J., Van Kooten, C., Merville, P., Grouard, G., Briere, F., Banchereau, J., Liu, Y. J. (1995) Generation of memory B cells and plasma cells in vitro. Science 268, 720-722.
8. Agematsu, K., Hokibara, S., Nagumo, H., Shinozaki, K., Yamada, S., Komiyama, A. (1999) Plasma cell generation from B-lymphocytes via CD27/CD70 interaction. Leuk. Lymphoma 35, 219-225.
9. Jelinek, D. F., Lipsky, P. E. (1983) The role of B cell proliferation in the generation of immunoglobulin-secreting cells in man. J. Immunol. 130, 2597-2604.
10. Odendahl, M., Jacobi, A., Hansen, A., Feist, E., Hiepe, F., Burmester, G. R., Lipsky, P. E., Radbruch, A., Dorner, T. (2000) Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J. Immunol. 165, 5970-5979.
11. Horst, A., Hunzelmann, N., Arce, S., Herber, M., Manz, R. A., Radbruch, A., Nischt, R., Schmitz, J., Assenmacher, M. (2002) Detection and characterization of plasma cells in peripheral blood: correlation of IgE+ plasma cell frequency with IgE serum titre. Clin. Exp. Immunol. 130, 370-378.
12. Brieva, J. A., Roldan, E., De la Sen, M. L., Rodriguez, C. (1991) Human in vivo-induced spontaneous IgG-secreting cells from tonsil, blood and bone marrow exhibit different phenotype and functional level of maturation. Immunology 72, 580-583.
13. Medina, F., Segundo, C., Campos-Caro, A., Gonzalez-Garcia, I., Brieva, J. A. (2002) The heterogeneity shown by human plasma cells from tonsil, blood, and bone marrow reveals graded stages of increasing maturity, but local profiles of adhesion molecule expression. Blood 99, 2154-2161.
14. Snapper, C. M., Mond, J. J. (1993) Towards a comprehensive view of immunoglobulin class switching. Immunol. Today 14, 15-17.
15. Manz, R., Assenmacher, M., Pfluger, E., Miltenyi, S., Radbruch, A. (1995) Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix. Proc. Natl. Acad. Sci. USA 92, 1921-1925.
16. Boyum, A. (1968) Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand. J. Clin. Lab. Invest. Suppl. 97, 77-89.
17. Lyons, A. B., Parish, C. R. (1994) Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 171, 131-137.
18. Volkman, D. J., Allyn, S. P., Fauci, A. S. (1982) Antigen-induced in vitro antibody production in humans: tetanus toxoid-specific antibody synthesis. J. Immunol. 129, 107-112.
19. Czerkinsky, C. C., Nilsson, L. A., Nygren, H., Ouchterlony, O., Tarkowski, A. (1983) A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells. J. Immunol. Methods 65, 109-121.
20. Halper, J., Fu, S. M., Wang, C. Y., Winchester, R., Kunkel, H. G. (1978) Patterns of expression of human "Ia-like" antigens during the terminal stages of B cell development. J. Immunol. 120, 1480-1484.
21. Manz, R. A., Lohning, M., Cassese, G., Thiel, A., Radbruch, A. (1998) Survival of long-lived plasma cells is independent of antigen. Int. Immunol. 10, 1703-1711.
22. Tangye, S. G., Avery, D. T., Hodgkin, P. D. (2003) A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells. J. Immunol. 170, 261-269.
23. Terstappen, L. W., Johnsen, S., Segers-Nolten, I. M., Loken, M. R. (1990) Identification and characterization of plasma cells in normal human bone marrow by high-resolution flow cytometry. Blood 76, 1739-1747.
24. Won, W. J., Kearney, J. F. (2002) CD9 is a unique marker for marginal zone B cells, B1 cells, and plasma cells in mice. J. Immunol. 168, 5605-5611.
25. Bhan, A. K., Nadler, L. M., Stashenko, P., McCluskey, R. T., Schlossman, S. F. (1981) Stages of B cell differentiation in human lymphoid tissue. J. Exp. Med. 154, 737-749.
26. Angelin-Duclos, C., Cattoretti, G., Lin, K. I., Calame, K. (2000) Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J. Immunol. 165, 5462-5471.
27. Harada, Y., Kawano, M. M., Huang, N., Mahmoud, M. S., Lisukov, I. A., Mihara, K., Tsujimoto, T., Kuramoto, A. (1996) Identification of early plasma cells in peripheral blood and their clinical significance. Br. J. Haematol. 92, 184-191.
28. Jacob, J., Kassir, R., Kelsoe, G. (1991) In situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 173, 1165-1175.
29. Liu, Y. J., Zhang, J., Lane, P. J., Chan, E. Y., MacLennan, I. C. (1991) Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 21, 2951-2962.
30. Bowman, E. P., Kuklin, N. A., Youngman, K. R., Lazarus, N. H., Kunkel, E. J., Pan, J., Greenberg, H. B., Butcher, E. C. (2002) The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells. J. Exp. Med. 195, 269-275.
31. Merville, P., Dechanet, J., Desmouliere, A., Durand, I., de Bouteiller, O., Garrone, P., Banchereau, J., Liu, Y. J. (1996) Bcl-2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts. J. Exp. Med. 183, 227-236.
32. Garcia De Vinuesa, C., Gulbranson-Judge, A., Khan, M., O'Leary, P., Cascalho, M., Wabl, M., Klaus, G. G., Owen, M. J., MacLennan, I. C. (1999) Dendritic cells associated with plasmablast survival. Eur. J. Immunol. 29, 3712-3721.
33. Sze, D. M., Toellner, K. M., Garcia de Vinuesa, C., Taylor, D. R., MacLennan, I. C. (2000) Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival. J. Exp. Med. 192, 813-821.
34. Harada, H., Kawano, M. M., Huang, N., Harada, Y., Iwato, K., Tanabe, O., Tanaka, H., Sakai, A., Asaoku, H., Kuramoto, A. (1993) Phenotypic difference of normal plasma cells from mature myeloma cells. Blood 81, 2658-2663.
35. Mahmoud, M. S., Huang, N., Nobuyoshi, M., Lisukov, I. A., Tanaka, H., Kawano, M. M. (1996) Altered expression of Pax-5 gene in human myeloma cells. Blood 87, 4311-4315.
36. Manz, R. A., Radbruch, A. (2002) Plasma cells for a lifetime? Eur. J. Immunol. 32, 923-927.
37. Manz, R. A., Arce, S., Cassese, G., Hauser, A. E., Hiepe, F., Radbruch, A. (2002) Humoral immunity and long-lived plasma cells. Curr. Opin. Immunol. 14, 517-521.
38. Manz, R. A., Cassese, G., Thiel, A., Radbruch, A. (1999) Long-lived plasma cells survive independent of antigen. Curr. Top. Microbiol. Immunol. 246, 71-74.
39. Minges Wols, H. A., Underhill, G. H., Kansas, G. S., Witte, P. L. (2002) The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity. J. Immunol. 169, 4213-4221.