3'-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: Synthesis and anti-ras activity in radiation-resistant cells

Bioconjugate Chemistry

Volumn 11, Issue 2, 2000, Pages 153-160

  Rait, Antonina ^a   Pirollo, Kathleen ^a   Will, David W ^b   Peyman, Anush ^b   Rait, Vladimir ^a   Uhlmann, Eugen ^b   Chang, Esther H ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; BINDING SITE; CELL GROWTH; CHIMYL ALCOHOL; COMPLEMENTARY DNA; CYTOTOXICITY; GENE FUNCTION; GENE MUTATION; GENE REPRESSION; MOUSE; MULTIMODALITY CANCER THERAPY; OLIGONUCLEOTIDE; ONCOGENE; ONCOGENE RAS; RADIOSENSITIVITY; TUMOR CELL; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

CELL CULTURE; GENE EXPRESSION; RADIATION; RADIOTHERAPY; TOXICITY; TUMORS;

ANTI-SENSE OLIGODEOXYRIBONUCLEOTIDE; CELLULAR UPTAKE; GENES EXPRESSION; HUMAN TUMORS; HYBRIDISATION; HYDROPHOBIC TAILS; PHOSPHOROTHIOATES; RADIATION RESISTANT; RESISTANT CELLS; TUMOUR CELLS;

OLIGONUCLEOTIDES;

EID: 0034121346     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc990106n     Document Type: Article

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