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Volumn 377, Issue 1, 1996, Pages 67-70

Minimally modified oligonucleotides - Combination of end-capping

Author keywords

Nuclease resistance; Oligonucleotides; Partial modification; Protection pattern

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; NUCLEASE; OLIGONUCLEOTIDE; PHOSPHOROTHIOIC ACID;

EID: 0030020391     PISSN: 01773593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (50)

References (16)
  • 1
    • 0025015229 scopus 로고
    • Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides
    • Agrawal, S., Mayrand, S.H., Zamecnik, P.C., and Pederson, T. (1990). Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. Proc. Natl. Acad. Sei. USA 87,1401 -1405.
    • (1990) Proc. Natl. Acad. Sei. USA , vol.87 , pp. 1401-1405
    • Agrawal, S.1    Mayrand, S.H.2    Zamecnik, P.C.3    Pederson, T.4
  • 2
    • 0028176489 scopus 로고
    • bcr"abl tyrosine kinase autophosphorylation by oiigodeoxynucleotides of defined sequence and backbone structure
    • bcr"abl tyrosine kinase autophosphorylation by oiigodeoxynucleotides of defined sequence and backbone structure. Nucleic Acids Res. 22, 2150-2154.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2150-2154
    • Bergan, R.1    Connell, Y.2    Fahmy, B.3    Kyle, E.4    Neckers, L.5
  • 3
    • 0004244327 scopus 로고
    • Crooke, ST., and Lebleu, B., eds. Boca Raton, USA: CRC Press.
    • Crooke, ST., and Lebleu, B., eds. (1993). Antisense Research and Applications. (Boca Raton, USA: CRC Press).
    • (1993) Antisense Research and Applications.
  • 4
    • 0026573769 scopus 로고
    • Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNaseH: Implications for antisense technology
    • Gao, W.-Y, Han, F.-S., Storm, C., Egan, W., and Cheng, Y.-C. (1991). Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNaseH: Implications for antisense technology. Molecular Pharmacology 41,223-229.
    • (1991) Molecular Pharmacology , vol.41 , pp. 223-229
    • Gao, W.-Y.1    Han, F.-S.2    Storm, C.3    Egan, W.4    Cheng, Y.-C.5
  • 5
    • 0027418989 scopus 로고
    • Phosphorothioate-phosphodiester oligonucleotide co-polymers: Assessment for antisense application
    • Ghosh, M., Ghosh, K. and Cohen, J.S. (1993). Phosphorothioate-phosphodiester oligonucleotide co-polymers: assessment for antisense application. Anti-Cancer Drug Design 8,15-32.
    • (1993) Anti-Cancer Drug Design , vol.8 , pp. 15-32
    • Ghosh, M.1    Ghosh, K.2    Cohen, J.S.3
  • 6
    • 0027416659 scopus 로고
    • Chimeric oligodeoxynucleotide analogues: Enhanced cell uptake of structures which direct ribonuclease H with high specificity
    • Giles, R.V., Spilier, D.G., and Tidd, D.M. (1993). Chimeric oligodeoxynucleotide analogues: enhanced cell uptake of structures which direct ribonuclease H with high specificity. Anti-Cancer Drug Design 3,33-51.
    • (1993) Anti-Cancer Drug Design , vol.3 , pp. 33-51
    • Giles, R.V.1    Spilier, D.G.2    Tidd, D.M.3
  • 7
    • 0028949890 scopus 로고
    • Single base discrimination for ribonuclease H-dependent antisense effects within intact leukaemia cells
    • Giles, R.V., Ruddell, C.J., Spiller, D.G., Green, J.A., and Tidd, D.M. (1995). Single base discrimination for ribonuclease H-dependent antisense effects within intact leukaemia cells. Nucleic Acid Res. 23,954-961.
    • (1995) Nucleic Acid Res. , vol.23 , pp. 954-961
    • Giles, R.V.1    Ruddell, C.J.2    Spiller, D.G.3    Green, J.A.4    Tidd, D.M.5
  • 8
    • 0028815149 scopus 로고
    • Phosphorothioate oligonucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity sites on extracellular matrix
    • Guvakova, M.A., Yakubov, LA., Vlodavsky, I., Tonkinson, J.L, and Stein, C.A. (1995). Phosphorothioate oligonucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity sites on extracellular matrix. J. Biol. Chem. 270,2620-2627.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2620-2627
    • Guvakova, M.A.1    Yakubov, L.A.2    Vlodavsky, I.3    Tonkinson, J.L.4    Stein, C.A.5
  • 9
    • 0026048056 scopus 로고
    • Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection
    • Hoke, G.D., Draper, K., Freier, S., Gonzalez, C., Driver, V.B., Zounes, M.C., and Ecker, D.J. (1991). Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection. Nucleic Acid Res. 19,5743-5748.
    • (1991) Nucleic Acid Res. , vol.19 , pp. 5743-5748
    • Hoke, G.D.1    Draper, K.2    Freier, S.3    Gonzalez, C.4    Driver, V.B.5    Zounes, M.C.6    Ecker, D.J.7
  • 10
    • 0026969188 scopus 로고
    • Template, phosphorothioate oligonucleotides duplexes as inhibitors of HIV-1 reverse transcriptase
    • Maury, G., Abdelaziz, E., Mon/an, F., Muller, B., Imbach, J., and Goody, R.S. (1992). Template, phosphorothioate oligonucleotides duplexes as inhibitors of HIV-1 reverse transcriptase. Biochem. Biophys. Res. Commun. 186,1249-1256.
    • (1992) Biochem. Biophys. Res. Commun. , vol.186 , pp. 1249-1256
    • Maury, G.1    Abdelaziz, E.2    Monan, F.3    Muller, B.4    Imbach, J.5    Goody, R.S.6
  • 11
    • 0029268478 scopus 로고
    • Inhibition of viral growth by antisense oligonucleotides directed against the IE110 and the UL30 mRNA of Herpes Simplex Virus Type-1
    • Peyman, A., Helsberg, M., Kretzschmar, G., Mag, M., Grabley, S., and Uhlmann, E. (1995). Inhibition of viral growth by antisense oligonucleotides directed against the IE110 and the UL30 mRNA of Herpes Simplex Virus Type-1. Biol. Chem. HoppeSeyler 376,195-198.
    • (1995) Biol. Chem. HoppeSeyler , vol.376 , pp. 195-198
    • Peyman, A.1    Helsberg, M.2    Kretzschmar, G.3    Mag, M.4    Grabley, S.5    Uhlmann, E.6
  • 12
    • 0024296609 scopus 로고
    • Physicochemical properties of phosphorothioate oligodeoxynucleotides
    • Stein, C.A., Subasinghe, C., Shinozuka, K., and Cohen, J.S. (1988). Physicochemical properties of phosphorothioate oligodeoxynucleotides. Nucl. Acids Res. 16,3209-3221.
    • (1988) Nucl. Acids Res. , vol.16 , pp. 3209-3221
    • Stein, C.A.1    Subasinghe, C.2    Shinozuka, K.3    Cohen, J.S.4
  • 13
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
    • Stein, C.A., and Cheng, Y.-C. (1993). Antisense oligonucleotides as therapeutic agents - Is the bullet really magical? Science 267,1004-1912.
    • (1993) Science , vol.267 , pp. 1004-1912
    • Stein, C.A.1    Cheng, Y.-C.2
  • 14
    • 0027161566 scopus 로고
    • Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells
    • Stein, C.A., Tonkinson, J., Zhang, L.M., Yakubov, L, Gervasoni, J., Taub, R., and Rotenberg, S.A. (1993). Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells. Biochemistry 32,4855-4861.
    • (1993) Biochemistry , vol.32 , pp. 4855-4861
    • Stein, C.A.1    Tonkinson, J.2    Zhang, L.M.3    Yakubov4    Gervasoni5    Taub, R.6    Rotenberg, S.A.7
  • 15
    • 0028598020 scopus 로고
    • Inhibition of T4 polynucleotide kinase activity by phosphorothioate and chimeric oligodeoxynucleotides
    • Teasdale, R.M., Maison, S.J., Fisher, E., and Krieg, A.M. (1994). Inhibition of T4 polynucleotide kinase activity by phosphorothioate and chimeric oligodeoxynucleotides. Antisense Research and Development 4,295-297.
    • (1994) Antisense Research and Development , vol.4 , pp. 295-297
    • Teasdale, R.M.1    Maison, S.J.2    Fisher, E.3    Krieg, A.M.4
  • 16
    • 11944267365 scopus 로고
    • Antisense oligonucleotides -A new therapeutic principle
    • Uhlmann, E., and Peyman, A. (1990). Antisense oligonucleotides -A new therapeutic principle. Chem. Rev. 90,543-584.
    • (1990) Chem. Rev. , vol.90 , pp. 543-584
    • Uhlmann, E.1    Peyman, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.