-
2
-
-
0031818471
-
Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe
-
J. Bahler, J.Q. Wu, M.S. Longtine, N.G. Shah, A. McKenzie, A.B. Steever, A. Wach, P. Philippsen, and J.R. Pringle Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe Yeast 14 1998 943 951
-
(1998)
Yeast
, vol.14
, pp. 943-951
-
-
Bahler, J.1
Wu, J.Q.2
Longtine, M.S.3
Shah, N.G.4
McKenzie, A.5
Steever, A.B.6
Wach, A.7
Philippsen, P.8
Pringle, J.R.9
-
3
-
-
0017894322
-
Induction of 3-hydroxy-3-methylglutaryl coenzyme-A reductase-activity in human fibroblasts incubated with compactin (Ml-236B), a competitive inhibitor of reductase
-
M.S. Brown, J.R. Faust, J.L. Goldstein, I. Kaneko, and A. Endo Induction of 3-hydroxy-3-methylglutaryl coenzyme-A reductase-activity in human fibroblasts incubated with compactin (Ml-236B), a competitive inhibitor of reductase J. Biol. Chem. 253 1978 1121 1128
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 1121-1128
-
-
Brown, M.S.1
Faust, J.R.2
Goldstein, J.L.3
Kaneko, I.4
Endo, A.5
-
4
-
-
0028009916
-
Molecular cloning and characterization of the Schizosaccharomyces pombe his3 gene for use as a selectable marker
-
J.D. Burke, and K.L. Gould Molecular cloning and characterization of the Schizosaccharomyces pombe his3 gene for use as a selectable marker Mol. Gen. Genet. 242 1994 169 176
-
(1994)
Mol. Gen. Genet.
, vol.242
, pp. 169-176
-
-
Burke, J.D.1
Gould, K.L.2
-
5
-
-
0033599028
-
Transport-dependent proteolysis of SREBP: Relocation of Site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi
-
R.A. DeBose-Boyd, M.S. Brown, W.P. Li, A. Nohturfft, J.L. Goldstein, and P.J. Espenshade Transport-dependent proteolysis of SREBP: relocation of Site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi Cell 99 1999 703 712
-
(1999)
Cell
, vol.99
, pp. 703-712
-
-
Debose-Boyd, R.A.1
Brown, M.S.2
Li, W.P.3
Nohturfft, A.4
Goldstein, J.L.5
Espenshade, P.J.6
-
6
-
-
0037012907
-
Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila
-
I.Y. Dobrosotskaya, A.C. Seegmiller, M.S. Brown, J.L. Goldstein, and R.B. Rawson Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila Science 296 2002 879 883
-
(2002)
Science
, vol.296
, pp. 879-883
-
-
Dobrosotskaya, I.Y.1
Seegmiller, A.C.2
Brown, M.S.3
Goldstein, J.L.4
Rawson, R.B.5
-
7
-
-
0033529560
-
Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins
-
P.J. Espenshade, D. Cheng, J.L. Goldstein, and M.S. Brown Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins J. Biol. Chem. 274 1999 22795 22804
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22795-22804
-
-
Espenshade, P.J.1
Cheng, D.2
Goldstein, J.L.3
Brown, M.S.4
-
8
-
-
1542379024
-
Membrane topology of human Insig-1, a protein regulator of lipid synthesis
-
J.D. Feramisco, J.L. Goldstein, and M.S. Brown Membrane topology of human Insig-1, a protein regulator of lipid synthesis J. Biol. Chem. 279 2004 8487 8496
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 8487-8496
-
-
Feramisco, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
9
-
-
0035937843
-
An oxysterol-derived positive signal for 3-hydroxy-3-methylglutaryl-CoA reductase degradation in yeast
-
R.G. Gardner, H. Shan, S.P. Matsuda, and R.Y. Hampton An oxysterol-derived positive signal for 3-hydroxy-3-methylglutaryl-CoA reductase degradation in yeast J. Biol. Chem. 276 2001 8681 8694
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8681-8694
-
-
Gardner, R.G.1
Shan, H.2
Matsuda, S.P.3
Hampton, R.Y.4
-
10
-
-
0025120211
-
Regulation of the mevalonate pathway
-
J.L. Goldstein, and M.S. Brown Regulation of the mevalonate pathway Nature 343 1990 425 430
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
11
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
J.D. Horton, J.L. Goldstein, and M.S. Brown SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver J. Clin. Invest. 109 2002 1125 1131
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
12
-
-
0142027805
-
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
-
J.D. Horton, N.A. Shah, J.A. Warrington, N.N. Anderson, S.W. Park, M.S. Brown, and J.L. Goldstein Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes Proc. Natl. Acad. Sci. USA 100 2003 12027 12032
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12027-12032
-
-
Horton, J.D.1
Shah, N.A.2
Warrington, J.A.3
Anderson, N.N.4
Park, S.W.5
Brown, M.S.6
Goldstein, J.L.7
-
13
-
-
0027139362
-
SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element
-
X.X. Hua, C. Yokoyama, J. Wu, M.R. Briggs, M.S. Brown, J.L. Goldstein, and X.D. Wang SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element Proc. Natl. Acad. Sci. USA 90 1993 11603 11607
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11603-11607
-
-
Hua, X.X.1
Yokoyama, C.2
Wu, J.3
Briggs, M.R.4
Brown, M.S.5
Goldstein, J.L.6
Wang, X.D.7
-
14
-
-
0028607143
-
Regulated degradation of the transcription factor Gcn4
-
D. Kornitzer, B. Raboy, R.G. Kulka, and G.R. Fink Regulated degradation of the transcription factor Gcn4 EMBO J. 13 1994 6021 6030
-
(1994)
EMBO J.
, vol.13
, pp. 6021-6030
-
-
Kornitzer, D.1
Raboy, B.2
Kulka, R.G.3
Fink, G.R.4
-
15
-
-
0032052761
-
Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast
-
K.E. Kwast, P.V. Burke, and R.O. Poyton Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast J. Exp. Biol. 201 1998 1177 1195
-
(1998)
J. Exp. Biol.
, vol.201
, pp. 1177-1195
-
-
Kwast, K.E.1
Burke, P.V.2
Poyton, R.O.3
-
16
-
-
0036135461
-
Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: Functional roles of Rox1 and other factors in mediating the anoxic response
-
K.E. Kwast, L.C. Lai, N. Menda, D.T. James III, S. Aref, and P.V. Burke Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response J. Bacteriol. 184 2002 250 265
-
(2002)
J. Bacteriol.
, vol.184
, pp. 250-265
-
-
Kwast, K.E.1
Lai, L.C.2
Menda, N.3
James III, D.T.4
Aref, S.5
Burke, P.V.6
-
17
-
-
0037137346
-
Cholesterol homeostasis: Not until the SCAP lady INSIGs
-
C.J. Loewen, and T.P. Levine Cholesterol homeostasis: not until the SCAP lady INSIGs Curr. Biol. 12 2002 R779 R781
-
(2002)
Curr. Biol.
, vol.12
-
-
Loewen, C.J.1
Levine, T.P.2
-
18
-
-
0025743249
-
Involvement of heme components in sterol metabolism of Saccharomyces cerevisiae
-
R.T. Lorenz, and L.W. Parks Involvement of heme components in sterol metabolism of Saccharomyces cerevisiae Lipids 26 1991 598 603
-
(1991)
Lipids
, vol.26
, pp. 598-603
-
-
Lorenz, R.T.1
Parks, L.W.2
-
19
-
-
0035873619
-
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation
-
M. Matsuda, B.S. Korn, R.E. Hammer, Y.A. Moon, R. Komuro, J.D. Horton, J.L. Goldstein, M.S. Brown, and I. Shimomura SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation Genes Dev. 15 2001 1206 1216
-
(2001)
Genes Dev.
, vol.15
, pp. 1206-1216
-
-
Matsuda, M.1
Korn, B.S.2
Hammer, R.E.3
Moon, Y.A.4
Komuro, R.5
Horton, J.D.6
Goldstein, J.L.7
Brown, M.S.8
Shimomura, I.9
-
20
-
-
0037237117
-
C. elegans: A model for exploring the genetics of fat storage
-
R.M. McKay, J.P. McKay, L. Avery, and J.M. Graff C. elegans: a model for exploring the genetics of fat storage Dev. Cell 4 2003 131 142
-
(2003)
Dev. Cell
, vol.4
, pp. 131-142
-
-
McKay, R.M.1
McKay, J.P.2
Avery, L.3
Graff, J.M.4
-
21
-
-
0026025891
-
Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
-
S. Moreno, A. Klar, and P. Nurse Molecular genetic analysis of fission yeast Schizosaccharomyces pombe Methods Enzymol. 194 1991 795 823
-
(1991)
Methods Enzymol.
, vol.194
, pp. 795-823
-
-
Moreno, S.1
Klar, A.2
Nurse, P.3
-
22
-
-
0032524465
-
Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 Å resolution
-
A. Parraga, L. Bellsolell, A.R. Ferre-D'Amare, and S.K. Burley Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 Å resolution Structure 6 1998 661 672
-
(1998)
Structure
, vol.6
, pp. 661-672
-
-
Parraga, A.1
Bellsolell, L.2
Ferre-D'Amare, A.R.3
Burley, S.K.4
-
23
-
-
0043172415
-
The SREBP pathway-insights from Insigs and insects
-
R.B. Rawson The SREBP pathway-insights from Insigs and insects Nat. Rev. Mol. Cell Biol. 4 2003 631 640
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 631-640
-
-
Rawson, R.B.1
-
24
-
-
0033215204
-
Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein
-
R.B. Rawson, R. DeBose-Boyd, J.L. Goldstein, and M.S. Brown Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein J. Biol. Chem. 274 1999 28549 28556
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28549-28556
-
-
Rawson, R.B.1
Debose-Boyd, R.2
Goldstein, J.L.3
Brown, M.S.4
-
25
-
-
0142248154
-
Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae
-
E. Rosenfeld, and B. Beauvoit Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae Yeast 20 2003 1115 1144
-
(2003)
Yeast
, vol.20
, pp. 1115-1144
-
-
Rosenfeld, E.1
Beauvoit, B.2
-
27
-
-
0036480346
-
The SREBP pathway in Drosophila: Regulation by palmitate, not sterols
-
A.C. Seegmiller, I. Dobrosotskaya, J.L. Goldstein, Y.K. Ho, M.S. Brown, and R.B. Rawson The SREBP pathway in Drosophila: regulation by palmitate, not sterols Dev. Cell 2 2002 229 238
-
(2002)
Dev. Cell
, vol.2
, pp. 229-238
-
-
Seegmiller, A.C.1
Dobrosotskaya, I.2
Goldstein, J.L.3
Ho, Y.K.4
Brown, M.S.5
Rawson, R.B.6
-
28
-
-
0035313697
-
HIF-1 and mechanisms of hypoxia sensing
-
G.L. Semenza HIF-1 and mechanisms of hypoxia sensing Curr. Opin. Cell Biol. 13 2001 167 171
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 167-171
-
-
Semenza, G.L.1
-
30
-
-
0034810736
-
Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae
-
A. Vik, and J. Rine Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae Mol. Cell. Biol. 21 2001 6395 6405
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6395-6405
-
-
Vik, A.1
Rine, J.2
-
31
-
-
0028225462
-
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
-
X.D. Wang, R. Sato, M.S. Brown, X.X. Hua, and J.L. Goldstein SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis Cell 77 1994 53 62
-
(1994)
Cell
, vol.77
, pp. 53-62
-
-
Wang, X.D.1
Sato, R.2
Brown, M.S.3
Hua, X.X.4
Goldstein, J.L.5
-
32
-
-
0037031860
-
Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast
-
L.J. Wilcox, D.A. Balderes, B. Wharton, A.H. Tinkelenberg, G. Rao, and S.L. Sturley Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast J. Biol. Chem. 277 2002 32466 32472
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32466-32472
-
-
Wilcox, L.J.1
Balderes, D.A.2
Wharton, B.3
Tinkelenberg, A.H.4
Rao, G.5
Sturley, S.L.6
-
33
-
-
0028794516
-
Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C
-
F. Winston, C. Dollard, and S.L. Ricupero-Hovasse Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C Yeast 11 1995 53 55
-
(1995)
Yeast
, vol.11
, pp. 53-55
-
-
Winston, F.1
Dollard, C.2
Ricupero-Hovasse, S.L.3
-
34
-
-
0037168533
-
Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols
-
D. Yabe, Z.P. Xia, C.M. Adams, and R.B. Rawson Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols Proc. Natl. Acad. Sci. USA 99 2002 16672 16677
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 16672-16677
-
-
Yabe, D.1
Xia, Z.P.2
Adams, C.M.3
Rawson, R.B.4
-
35
-
-
0037162719
-
Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
-
T. Yang, P.J. Espenshade, M.E. Wright, D. Yabe, Y. Gong, R. Aebersold, J.L. Goldstein, and M.S. Brown Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER Cell 110 2002 489 500
-
(2002)
Cell
, vol.110
, pp. 489-500
-
-
Yang, T.1
Espenshade, P.J.2
Wright, M.E.3
Yabe, D.4
Gong, Y.5
Aebersold, R.6
Goldstein, J.L.7
Brown, M.S.8
-
36
-
-
0034625081
-
Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease
-
J. Ye, U.P. Dave, N.V. Grishin, J.L. Goldstein, and M.S. Brown Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease Proc. Natl. Acad. Sci. USA 97 2000 5123 5128
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5123-5128
-
-
Ye, J.1
Dave, U.P.2
Grishin, N.V.3
Goldstein, J.L.4
Brown, M.S.5
|