-
1
-
-
0034033642
-
Inhibitors of cyclin-dependent kinases as therapeutic agents for the treatment of cancer
-
Fry DW, Garrett MD. Inhibitors of cyclin-dependent kinases as therapeutic agents for the treatment of cancer. Curr Opin Oncol Endocr Metab Invest Drugs 2000; 2(1): 40-59.
-
(2000)
Curr Opin Oncol Endocr Metab Invest Drugs
, vol.2
, Issue.1
, pp. 40-59
-
-
Fry, D.W.1
Garrett, M.D.2
-
2
-
-
13244268318
-
Clinical anticancer drug development: Targeting the cyclindependent kinases
-
Benson C, Kaye S, Workman P, Garrett M, Walton M, de Bono J. Clinical anticancer drug development: targeting the cyclindependent kinases. Br J Cancer 2005; 92(1): 7-12.
-
(2005)
Br J Cancer
, vol.92
, Issue.1
, pp. 7-12
-
-
Benson, C.1
Kaye, S.2
Workman, P.3
Garrett, M.4
Walton, M.5
de Bono, J.6
-
3
-
-
0028958673
-
Association of Cdk-activating kinase subunits with transcription factor TFIIH
-
Serizawa H, Makela TP, Conaway JW, Conaway RC, Weinberg RA, Young RA. Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature 1995; 374(6519): 280-82.
-
(1995)
Nature
, vol.374
, Issue.6519
, pp. 280-282
-
-
Serizawa, H.1
Makela, T.P.2
Conaway, J.W.3
Conaway, R.C.4
Weinberg, R.A.5
Young, R.A.6
-
4
-
-
0028954227
-
Cdk-activating kinase complex is a component of human transcription factor TFIIH
-
Shiekhattar R, Mermelstein F, Fisher RP, et al. Cdk-activating kinase complex is a component of human transcription factor TFIIH. Nature 1995; 374(6519): 283-87.
-
(1995)
Nature
, vol.374
, Issue.6519
, pp. 283-287
-
-
Shiekhattar, R.1
Mermelstein, F.2
Fisher, R.P.3
-
5
-
-
0029880998
-
Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II
-
Leclerc V, Tassan JP, O'Farrell PH, Nigg EA, Leopold P. Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. Mol Biol Cell 1996; 7(4): 505-13.
-
(1996)
Mol Biol Cell
, vol.7
, Issue.4
, pp. 505-513
-
-
Leclerc, V.1
Tassan, J.P.2
O'Farrell, P.H.3
Nigg, E.A.4
Leopold, P.5
-
6
-
-
0029948789
-
Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II
-
Rickert P, Seghezzi W, Shanahan F, Cho H, Lees E. Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II. Oncogene 1996; 12(12): 2631-40.
-
(1996)
Oncogene
, vol.12
, Issue.12
, pp. 2631-2640
-
-
Rickert, P.1
Seghezzi, W.2
Shanahan, F.3
Cho, H.4
Lees, E.5
-
7
-
-
0033611561
-
Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases
-
Rickert P, Corden JL, Lees E. Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases. Oncogene 1999; 18(4): 1093-102.
-
(1999)
Oncogene
, vol.18
, Issue.4
, pp. 1093-1102
-
-
Rickert, P.1
Corden, J.L.2
Lees, E.3
-
8
-
-
13944277105
-
A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130
-
Garriga J, Jayaraman AL, Limon A, et al. A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130. Cell Cycle 2004; 3(10): 1320-30.
-
(2004)
Cell Cycle
, vol.3
, Issue.10
, pp. 1320-1330
-
-
Garriga, J.1
Jayaraman, A.L.2
Limon, A.3
-
9
-
-
1942421702
-
Cyclin C/Cdk3 promotes Rb-dependent G0 exit
-
Ren S, Rollins BJ. Cyclin C/Cdk3 promotes Rb-dependent G0 exit. Cell 2004; 117(2): 239-51.
-
(2004)
Cell
, vol.117
, Issue.2
, pp. 239-251
-
-
Ren, S.1
Rollins, B.J.2
-
10
-
-
0034831233
-
The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology
-
Maccioni RB, Otth C, Concha, II, Munoz JP. The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology. Eur J Biochem 2001; 268(6): 1518-27.
-
(2001)
Eur J Biochem
, vol.268
, Issue.6
, pp. 1518-1527
-
-
Maccioni, R.B.1
Otth, C.2
Concha, I.I.3
Munoz, J.P.4
-
11
-
-
0034745051
-
S and G2 phase roles for Cdk2 revealed by inducible expression of a dominantnegative mutant in human cells
-
Hu B, Mitra J, van den Heuvel S, Enders GH. S and G2 phase roles for Cdk2 revealed by inducible expression of a dominantnegative mutant in human cells. Mol Cell Biol 2001; 21(8): 2755-66.
-
(2001)
Mol Cell Biol
, vol.21
, Issue.8
, pp. 2755-2766
-
-
Hu, B.1
Mitra, J.2
van den Heuvel, S.3
Enders, G.H.4
-
12
-
-
0027742184
-
Distinct roles for cyclin-dependent kinases in cell cycle control
-
van den Heuvel S, Harlow E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science 1993; 262(5142): 2050-54.
-
(1993)
Science
, vol.262
, Issue.5142
, pp. 2050-2054
-
-
van den Heuvel, S.1
Harlow, E.2
-
13
-
-
0028909645
-
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition
-
Ohtsubo M, Theodoras AM, Schumacher J, Roberts JM, Pagano M. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol Cell Biol 1995; 15(5): 2612-24.
-
(1995)
Mol Cell Biol
, vol.15
, Issue.5
, pp. 2612-2624
-
-
Ohtsubo, M.1
Theodoras, A.M.2
Schumacher, J.3
Roberts, J.M.4
Pagano, M.5
-
14
-
-
0027298902
-
The Cdk2 kinase is required for the G1-to-S transition in mammalian cells
-
Tsai LH, Lees E, Faha B, Harlow E, Riabowol K. The Cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene 1993; 8(6): 1593-602.
-
(1993)
Oncogene
, vol.8
, Issue.6
, pp. 1593-1602
-
-
Tsai, L.H.1
Lees, E.2
Faha, B.3
Harlow, E.4
Riabowol, K.5
-
15
-
-
0026583746
-
Cyclin A is required at two points in the human cell cycle
-
Pagano M, Pepperkok R, Verde F, Ansorge W, Draetta G. Cyclin A is required at two points in the human cell cycle. Embo J 1992; 11(3): 961-71.
-
(1992)
Embo J
, vol.11
, Issue.3
, pp. 961-971
-
-
Pagano, M.1
Pepperkok, R.2
Verde, F.3
Ansorge, W.4
Draetta, G.5
-
16
-
-
0041327168
-
Proliferation of cancer cells despite CDK2 inhibition
-
Tetsu O, McCormick F. Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell 2003; 3(3): 233-45.
-
(2003)
Cancer Cell
, vol.3
, Issue.3
, pp. 233-245
-
-
Tetsu, O.1
McCormick, F.2
-
17
-
-
0041854279
-
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
-
Ortega S, Prieto I, Odajima J, et al. Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice. Nat Genet 2003; 35(1): 25-31.
-
(2003)
Nat Genet
, vol.35
, Issue.1
, pp. 25-31
-
-
Ortega, S.1
Prieto, I.2
Odajima, J.3
-
18
-
-
0142116249
-
Cdk2 knockout mice are viable
-
Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P. Cdk2 knockout mice are viable. Curr Biol 2003; 13(20): 1775-85.
-
(2003)
Curr Biol
, vol.13
, Issue.20
, pp. 1775-1785
-
-
Berthet, C.1
Aleem, E.2
Coppola, V.3
Tessarollo, L.4
Kaldis, P.5
-
19
-
-
0032937751
-
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia
-
Rane SG, Dubus P, Mettus RV, et al. Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia. Nat Genet 1999; 22(1): 44-52.
-
(1999)
Nat Genet
, vol.22
, Issue.1
, pp. 44-52
-
-
Rane, S.G.1
Dubus, P.2
Mettus, R.V.3
-
20
-
-
0032849353
-
Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity
-
Tsutsui T, Hesabi B, Moons DS, et al. Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Mol Cell Biol 1999; 19(10): 7011-19.
-
(1999)
Mol Cell Biol
, vol.19
, Issue.10
, pp. 7011-7019
-
-
Tsutsui, T.1
Hesabi, B.2
Moons, D.S.3
-
21
-
-
4444247138
-
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
-
Malumbres M, Sotillo R, Santamaria D, et al. Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell 2004; 118(4): 493-504.
-
(2004)
Cell
, vol.118
, Issue.4
, pp. 493-504
-
-
Malumbres, M.1
Sotillo, R.2
Santamaria, D.3
-
22
-
-
0141737069
-
Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells
-
Parisi T, Beck AR, Rougier N, et al. Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells. Embo J 2003; 22(18): 4794-803.
-
(2003)
Embo J
, vol.22
, Issue.18
, pp. 4794-4803
-
-
Parisi, T.1
Beck, A.R.2
Rougier, N.3
-
23
-
-
0042528364
-
Cyclin E ablation in the mouse
-
Geng Y, Yu Q, Sicinska E, et al. Cyclin E ablation in the mouse. Cell 2003; 114(4): 431-43.
-
(2003)
Cell
, vol.114
, Issue.4
, pp. 431-443
-
-
Geng, Y.1
Yu, Q.2
Sicinska, E.3
-
24
-
-
0028889751
-
Mice lacking cyclin D1 are small and show defects in eye and mammary gland development
-
Fantl V, Stamp G, Andrews A, Rosewell I, Dickson C. Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. Genes Dev 1995; 9(19): 2364-72.
-
(1995)
Genes Dev
, vol.9
, Issue.19
, pp. 2364-2372
-
-
Fantl, V.1
Stamp, G.2
Andrews, A.3
Rosewell, I.4
Dickson, C.5
-
25
-
-
0029111934
-
Cyclin D1 provides a link between development and oncogenesis in the retina and breast
-
Sicinski P, Donaher JL, Parker SB, et al. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell 1995; 82(4): 621-30.
-
(1995)
Cell
, vol.82
, Issue.4
, pp. 621-630
-
-
Sicinski, P.1
Donaher, J.L.2
Parker, S.B.3
-
26
-
-
11144316653
-
Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells
-
Hahntow IN, Schneller F, Oelsner M, et al. Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells. Leukemia 2004; 18(4): 747-55.
-
(2004)
Leukemia
, vol.18
, Issue.4
, pp. 747-755
-
-
Hahntow, I.N.1
Schneller, F.2
Oelsner, M.3
-
27
-
-
0037210732
-
Flavopiridol, a cyclin dependent kinase (CDK) inhibitor, induces apoptosis by regulating Bcl-x in oral cancer cells
-
Mihara M, Shintani S, Nakashiro K, Hamakawa H. Flavopiridol, a cyclin dependent kinase (CDK) inhibitor, induces apoptosis by regulating Bcl-x in oral cancer cells. Oral Oncol 2003; 39(1): 49-55.
-
(2003)
Oral Oncol
, vol.39
, Issue.1
, pp. 49-55
-
-
Mihara, M.1
Shintani, S.2
Nakashiro, K.3
Hamakawa, H.4
-
28
-
-
0035881591
-
A novel Cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells
-
Lane ME, Yu B, Rice A, Lipson KE, Liang C, Sun L, et al. A novel Cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells. Cancer Res 2001; 61(16): 6170-77.
-
(2001)
Cancer Res
, vol.61
, Issue.16
, pp. 6170-6177
-
-
Lane, M.E.1
Yu, B.2
Rice, A.3
Lipson, K.E.4
Liang, C.5
Sun, L.6
-
29
-
-
0033551066
-
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
-
Chen YN, Sharma SK, Ramsey TM, et al. Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists. Proc Natl Acad Sci USA 1999; 96(8): 4325-29.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.8
, pp. 4325-4329
-
-
Chen, Y.N.1
Sharma, S.K.2
Ramsey, T.M.3
-
30
-
-
1642373327
-
Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line
-
Abal M, Bras-Goncalves R, Judde JG, et al. Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line. Oncogene 2004; 23(9): 1737-44.
-
(2004)
Oncogene
, vol.23
, Issue.9
, pp. 1737-1744
-
-
Abal, M.1
Bras-Goncalves, R.2
Judde, J.G.3
-
31
-
-
0030609024
-
p16INK4 expression is associated with the increased sensitivity of human non-small cell lung cancer cells to DNA topoisomerase I inhibitors
-
Fukuoka K, Adachi J, Nishio K, et al. p16INK4 expression is associated with the increased sensitivity of human non-small cell lung cancer cells to DNA topoisomerase I inhibitors. Jpn J Cancer Res 1997; 88(10): 1009-16.
-
(1997)
Jpn J Cancer Res
, vol.88
, Issue.10
, pp. 1009-1016
-
-
Fukuoka, K.1
Adachi, J.2
Nishio, K.3
-
32
-
-
0036282745
-
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
-
Konishi Y, Lehtinen M, Donovan N, Bonni A. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell 2002; 9(5): 1005-16.
-
(2002)
Mol Cell
, vol.9
, Issue.5
, pp. 1005-1016
-
-
Konishi, Y.1
Lehtinen, M.2
Donovan, N.3
Bonni, A.4
-
33
-
-
0029880622
-
Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases
-
Meikrantz W, Schlegel R. Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases. J Biol Chem 1996; 271(17): 10205-09.
-
(1996)
J Biol Chem
, vol.271
, Issue.17
, pp. 10205-10209
-
-
Meikrantz, W.1
Schlegel, R.2
-
34
-
-
0037442820
-
Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition
-
Rideout HJ, Wang Q, Park DS, Stefanis L. Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition. J Neurosci 2003; 23(4): 1237-45.
-
(2003)
J Neurosci
, vol.23
, Issue.4
, pp. 1237-1245
-
-
Rideout, H.J.1
Wang, Q.2
Park, D.S.3
Stefanis, L.4
-
35
-
-
0029982829
-
Reversible, p16-mediated cell cycle arrest as protection from chemotherapy
-
Stone S, Dayananth P, Kamb A. Reversible, p16-mediated cell cycle arrest as protection from chemotherapy. Cancer Res 1996; 56(14): 3199-202.
-
(1996)
Cancer Res
, vol.56
, Issue.14
, pp. 3199-3202
-
-
Stone, S.1
Dayananth, P.2
Kamb, A.3
-
36
-
-
0033231483
-
Involvement of cyclin-dependent kinase activities in CD437-induced apoptosis
-
Hsu SL, Yin SC, Liu MC, Reichert U, Ho WL. Involvement of cyclin-dependent kinase activities in CD437-induced apoptosis. Exp Cell Res 1999; 252(2): 332-41.
-
(1999)
Exp Cell Res
, vol.252
, Issue.2
, pp. 332-341
-
-
Hsu, S.L.1
Yin, S.C.2
Liu, M.C.3
Reichert, U.4
Ho, W.L.5
-
37
-
-
0028176485
-
Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275
-
Losiewicz MD, Carlson BA, Kaur G, Sausville EA, Worland PJ. Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275. Biochem Biophys Res Commun 1994; 201(2): 589-95.
-
(1994)
Biochem Biophys Res Commun
, vol.201
, Issue.2
, pp. 589-595
-
-
Losiewicz, M.D.1
Carlson, B.A.2
Kaur, G.3
Sausville, E.A.4
Worland, P.J.5
-
38
-
-
0029665778
-
Flavopiridol induces G1 arrest with inhibition of cyclindependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells
-
Carlson BA, Dubay MM, Sausville EA, Brizuela L, Worland PJ. Flavopiridol induces G1 arrest with inhibition of cyclindependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. Cancer Res 1996; 56(13): 2973-78.
-
(1996)
Cancer Res
, vol.56
, Issue.13
, pp. 2973-2978
-
-
Carlson, B.A.1
Dubay, M.M.2
Sausville, E.A.3
Brizuela, L.4
Worland, P.J.5
-
39
-
-
0029904810
-
Flavopiridol: A cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells
-
Bible KC, Kaufmann SH. Flavopiridol: a cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells. Cancer Res 1996; 56(21): 4856-61.
-
(1996)
Cancer Res
, vol.56
, Issue.21
, pp. 4856-4861
-
-
Bible, K.C.1
Kaufmann, S.H.2
-
40
-
-
0026452974
-
Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275
-
Kaur G, Stetler-Stevenson M, Sebers S, et al. Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275. J Natl Cancer Inst 1992; 84(22): 1736-40.
-
(1992)
J Natl Cancer Inst
, vol.84
, Issue.22
, pp. 1736-1740
-
-
Kaur, G.1
Stetler-Stevenson, M.2
Sebers, S.3
-
41
-
-
0031019034
-
Flavopiridol (L86-8275): Selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells
-
Drees M, Dengler WA, Roth T, et al. Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells. Clin Cancer Res 1997; 3(2): 273-79.
-
(1997)
Clin Cancer Res
, vol.3
, Issue.2
, pp. 273-279
-
-
Drees, M.1
Dengler, W.A.2
Roth, T.3
-
42
-
-
0032212885
-
Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis
-
Patel V, Senderowicz AM, Pinto D. Jr, et al. Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis. J Clin Invest 1998; 102(9): 1674-81.
-
(1998)
J Clin Invest
, vol.102
, Issue.9
, pp. 1674-1681
-
-
Patel, V.1
Senderowicz, A.M.2
Pinto Jr., D.3
-
43
-
-
0031670668
-
Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms
-
Senderowicz AM, Headlee D, Stinson SF, et al. Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms. J Clin Oncol 1998; 16(9): 2986-99.
-
(1998)
J Clin Oncol
, vol.16
, Issue.9
, pp. 2986-2999
-
-
Senderowicz, A.M.1
Headlee, D.2
Stinson, S.F.3
-
44
-
-
0036789539
-
Phase I clinical and pharmacokinetic study of flavopiridol administered as a daily 1-hour infusion in patients with advanced neoplasms
-
Tan AR, Headlee D, Messmann R, et al. Phase I clinical and pharmacokinetic study of flavopiridol administered as a daily 1-hour infusion in patients with advanced neoplasms. J Clin Oncol 2002; 20(19): 4074-82.
-
(2002)
J Clin Oncol
, vol.20
, Issue.19
, pp. 4074-4082
-
-
Tan, A.R.1
Headlee, D.2
Messmann, R.3
-
45
-
-
0033955395
-
Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: A University of Chicago Phase II Consortium study
-
Stadler WM, Vogelzang NJ, Amato R, et al. Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: a University of Chicago Phase II Consortium study. J Clin Oncol 2000; 18(2): 371-75.
-
(2000)
J Clin Oncol
, vol.18
, Issue.2
, pp. 371-375
-
-
Stadler, W.M.1
Vogelzang, N.J.2
Amato, R.3
-
46
-
-
0035300684
-
Phase II study of the cyclin-dependent kinase inhibitor flavopiridol administered to patients with advanced gastric carcinoma
-
Schwartz GK, Ilson D, Saltz L, et al. Phase II study of the cyclin-dependent kinase inhibitor flavopiridol administered to patients with advanced gastric carcinoma. J Clin Oncol 2001; 19(7): 1985-92.
-
(2001)
J Clin Oncol
, vol.19
, Issue.7
, pp. 1985-1992
-
-
Schwartz, G.K.1
Ilson, D.2
Saltz, L.3
-
47
-
-
3542996265
-
Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma
-
Burdette-Radoux S, Tozer RG, Lohmann RC, et al. Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma. Invest New Drugs 2004; 22(3): 315-22.
-
(2004)
Invest New Drugs
, vol.22
, Issue.3
, pp. 315-322
-
-
Burdette-Radoux, S.1
Tozer, R.G.2
Lohmann, R.C.3
-
48
-
-
0038473927
-
Flavopiridol in untreated or relapsed mantle-cell lymphoma: Results of a phase II study of the National Cancer Institute of Canada Clinical Trials Group
-
Kouroukis CT, Belch A, Crump M, et al. Flavopiridol in untreated or relapsed mantle-cell lymphoma: results of a phase II study of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2003; 21(9): 1740-45.
-
(2003)
J Clin Oncol
, vol.21
, Issue.9
, pp. 1740-1745
-
-
Kouroukis, C.T.1
Belch, A.2
Crump, M.3
-
49
-
-
0031037714
-
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, Cdk2 and Cdk5
-
Meijer L, Borgne A, Mulner O, et al. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, Cdk2 and Cdk5. Eur J Biochem 1997; 243(1-2): 527-36.
-
(1997)
Eur J Biochem
, vol.243
, Issue.1-2
, pp. 527-536
-
-
Meijer, L.1
Borgne, A.2
Mulner, O.3
-
50
-
-
0037058678
-
In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R-roscovitine)
-
McClue SJ, Blake D, Clarke R, et al. In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R-roscovitine). Int J Cancer 2002; 102(5): 463-68.
-
(2002)
Int J Cancer
, vol.102
, Issue.5
, pp. 463-468
-
-
McClue, S.J.1
Blake, D.2
Clarke, R.3
-
51
-
-
0033561531
-
Roscovitine induces cell death and morphological changes indicative of apoptosis in MDA-MB-231 breast cancer cells
-
Mgbonyebi OP, Russo J, Russo IH. Roscovitine induces cell death and morphological changes indicative of apoptosis in MDA-MB-231 breast cancer cells. Cancer Res 1999; 59(8): 1903-10.
-
(1999)
Cancer Res
, vol.59
, Issue.8
, pp. 1903-1910
-
-
Mgbonyebi, O.P.1
Russo, J.2
Russo, I.H.3
-
52
-
-
12144285797
-
N-(cycloalkylamino)-acyl-2-aminothiazole inhibitors of cyclin dependent kinase 2
-
Misra RN, Xiao HY, Kim KS, et al. N-(cycloalkylamino)-acyl-2-aminothiazole inhibitors of cyclin dependent kinase 2. J Med Chem 2004; 47(7): 1719-28.
-
(2004)
J Med Chem
, vol.47
, Issue.7
, pp. 1719-1728
-
-
Misra, R.N.1
Xiao, H.Y.2
Kim, K.S.3
-
53
-
-
0024518183
-
UCN-01 and UCN-02, new selective inhibitors of protein kinase C.I. Screening, producing organism and fermentation
-
Takahashi I, Asano K, Kawamoto I, Tamaoki T, Nakano H. UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation. J Antibiot (Tokyo) 1989; 42(4): 564-70.
-
(1989)
J Antibiot (Tokyo)
, vol.42
, Issue.4
, pp. 564-570
-
-
Takahashi, I.1
Asano, K.2
Kawamoto, I.3
Tamaoki, T.4
Nakano, H.5
-
54
-
-
0029871688
-
UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclindependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line
-
Kawakami K, Futami H, Takahara J, Yamaguchi K. UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclindependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line. Biochem Biophys Res Commun 1996; 219(3): 778-83.
-
(1996)
Biochem Biophys Res Commun
, vol.219
, Issue.3
, pp. 778-783
-
-
Kawakami, K.1
Futami, H.2
Takahara, J.3
Yamaguchi, K.4
-
55
-
-
0037034928
-
Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine)
-
Sato S, Fujita N, Tsuruo T. Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine). Oncogene 2002; 21(11): 1727-38.
-
(2002)
Oncogene
, vol.21
, Issue.11
, pp. 1727-1738
-
-
Sato, S.1
Fujita, N.2
Tsuruo, T.3
-
56
-
-
0034655281
-
The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1
-
Busby EC, Leistritz DF, Abraham RT, Karnitz LM, Sarkaria JN. The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1. Cancer Res 2000; 60(8): 2108-12.
-
(2000)
Cancer Res
, vol.60
, Issue.8
, pp. 2108-2112
-
-
Busby, E.C.1
Leistritz, D.F.2
Abraham, R.T.3
Karnitz, L.M.4
Sarkaria, J.N.5
-
57
-
-
0026425587
-
Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models
-
Akinaga S, Gomi K, Morimoto M, Tamaoki T, Okabe M. Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models. Cancer Res 1991; 51(18): 4888-92.
-
(1991)
Cancer Res
, vol.51
, Issue.18
, pp. 4888-4892
-
-
Akinaga, S.1
Gomi, K.2
Morimoto, M.3
Tamaoki, T.4
Okabe, M.5
-
58
-
-
0027157590
-
Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells
-
Seynaeve CM, Stetler-Stevenson M, Sebers S, Kaur G, Sausville EA, Worland PJ. Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells. Cancer Res 1993; 53(9): 2081-86.
-
(1993)
Cancer Res
, vol.53
, Issue.9
, pp. 2081-2086
-
-
Seynaeve, C.M.1
Stetler-Stevenson, M.2
Sebers, S.3
Kaur, G.4
Sausville, E.A.5
Worland, P.J.6
-
59
-
-
0035871444
-
Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms
-
Sausville EA, Arbuck SG, Messmann R, et al. Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms. J Clin Oncol 2001; 19(8): 2319-33.
-
(2001)
J Clin Oncol
, vol.19
, Issue.8
, pp. 2319-2333
-
-
Sausville, E.A.1
Arbuck, S.G.2
Messmann, R.3
-
60
-
-
20144373035
-
Phase I trial of the cyclin-dependent kinase inhibitor and protein kinase C inhibitor 7-hydroxystaurosporine in combination with Fluorouracil in patients with advanced solid tumors
-
Kortmansky J, Shah MA, Kaubisch A, et al. Phase I trial of the cyclin-dependent kinase inhibitor and protein kinase C inhibitor 7-hydroxystaurosporine in combination with Fluorouracil in patients with advanced solid tumors. J Clin Oncol 2005; 23(9): 1875-84.
-
(2005)
J Clin Oncol
, vol.23
, Issue.9
, pp. 1875-1884
-
-
Kortmansky, J.1
Shah, M.A.2
Kaubisch, A.3
-
61
-
-
20444506407
-
The cyclin-dependent kinase inhibitor UCN-01 plus cisplatin in advanced solid tumors: A California cancer consortium phase I pharmacokinetic and molecular correlative trial
-
Lara PN Jr, Mack PC, Synold T, et al. The cyclin-dependent kinase inhibitor UCN-01 plus cisplatin in advanced solid tumors: a California cancer consortium phase I pharmacokinetic and molecular correlative trial. Clin Cancer Res 2005; 11(12): 4444-50.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.12
, pp. 4444-4450
-
-
Lara Jr., P.N.1
Mack, P.C.2
Synold, T.3
-
62
-
-
26844564550
-
ZK-304709, the oral multitarget tumor growth inhibitor, acts via inhibition of cell cycle progression and tumor-induced angiogenesis
-
Meeting; abstract 5842
-
Siemeister G, Briem H, Brumby T, et al. ZK-304709, the oral multitarget tumor growth inhibitor, acts via inhibition of cell cycle progression and tumor-induced angiogenesis. Proceedings of the American Association of Cancer Research 2005 Meeting; abstract 5842.
-
(2005)
Proceedings of the American Association of Cancer Research
-
-
Siemeister, G.1
Briem, H.2
Brumby, T.3
-
63
-
-
9444228344
-
Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts
-
Fry DW, Harvey PJ, Keller PR, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Molecular Cancer Therapeutics 2004; 3 (11): 1427-37.
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.11
, pp. 1427-1437
-
-
Fry, D.W.1
Harvey, P.J.2
Keller, P.R.3
-
64
-
-
0033760789
-
Inhibitors of cyclin-dependent kinases as anticancer therapeutics
-
Fiswcher PM, Lane DP. Inhibitors of cyclin-dependent kinases as anticancer therapeutics. Curr Med Chem 2000; 7: 1213-45.
-
(2000)
Curr Med Chem
, vol.7
, pp. 1213-1245
-
-
Fiswcher, P.M.1
Lane, D.P.2
-
65
-
-
35448947567
-
-
In:, Philadelphia, Academic Press
-
Kimball SD, Webster KR. In: Annual Reports in Medicinal Chem-36, Cell cycle kinases and checkpoint regulation in cancer, Philadelphia, Academic Press. 2001; 139-48.
-
(2001)
Annual Reports in Medicinal Chem-36, Cell cycle kinases and checkpoint regulation in cancer
, pp. 139-148
-
-
Kimball, S.D.1
Webster, K.R.2
-
66
-
-
84873595966
-
-
WO04004632A2, WO04004632A3 (2004) and WO04004632C1
-
Lal, B., Joshi, K.S., Kulkarni, S.A., Mascarenhas, M., Kamble, S.G., Rathos, M.J., Joshi R.D.: WO04004632A2, WO04004632A3 (2004) and WO04004632C1 (2005).
-
(2005)
-
-
Lal, B.1
Joshi, K.S.2
Kulkarni, S.A.3
Mascarenhas, M.4
Kamble, S.G.5
Rathos, M.J.6
Joshi, R.D.7
-
67
-
-
84873587991
-
-
WO04016612A2 and WO04016612A3
-
Fischer, P., Jarman, M., McDonald, E., Nutley, B., Raynaud, F., Wilson, S., Workman, P.: WO04016612A2 and WO04016612A3 (2004).
-
(2004)
-
-
Fischer, P.1
Jarman, M.2
McDonald, E.3
Nutley, B.4
Raynaud, F.5
Wilson, S.6
Workman, P.7
-
68
-
-
84873572609
-
-
WO04016613A2 and WO04016613A3
-
Fischer, P., Jarman, M., McDonald, E. Nutley, B., Raynaud, F., Wilson, S., Workman, P.: WO04016613A2 and WO04016613A3 (2004).
-
(2004)
-
-
Fischer, P.1
Jarman, M.2
McDonald, E.3
Nutley, B.4
Raynaud, F.5
Wilson, S.6
Workman, P.7
-
69
-
-
84873572046
-
-
WO04026310A1 (2004) and WO04026310C1
-
Paruch, K., Guzi, T.J., Dwyer, M.P., Doll, R.J., Girijavallabhan, V.M.: WO04026310A1 (2004) and WO04026310C1 (2005).
-
(2005)
-
-
Paruch, K.1
Guzi, T.J.2
Dwyer, M.P.3
Doll, R.J.4
Girijavallabhan, V.M.5
-
70
-
-
84873598194
-
-
WO04026877A1
-
Paruch, K., Guzi, T.J., Dwyer, M.P., Doll, R.J., Girijavallabhan, V.M., Mallams.K.: WO04026877A1 (2004).
-
(2004)
-
-
Paruch, K.1
Guzi, T.J.2
Dwyer, M.P.3
Doll, R.J.4
Girijavallabhan, V.M.5
Mallams, K.6
-
71
-
-
84873581936
-
-
WO04026867A2 and WO04026867A3
-
Dwyer, M.P., Guzi, T.J., Paruch, K., Doll, R.J., Keertikar, K.M., Girijavallabhan, V.M.: WO04026867A2 and WO04026867A3 (2004).
-
(2004)
-
-
Dwyer, M.P.1
Guzi, T.J.2
Paruch, K.3
Doll, R.J.4
Keertikar, K.M.5
Girijavallabhan, V.M.6
-
72
-
-
84873605216
-
-
WO04022559A1
-
Guzi, T.J., Paruch, K., Dwyer, M.P., Doll, R.J., Girijavallabhan, V.M., Dillard, L.W., Tran, V.D., He, Z.M., James, R.A., Park, H.: WO04022559A1 (2004).
-
(2004)
-
-
Guzi, T.J.1
Paruch, K.2
Dwyer, M.P.3
Doll, R.J.4
Girijavallabhan, V.M.5
Dillard, L.W.6
Tran, V.D.7
He, Z.M.8
James, R.A.9
Park, H.10
-
73
-
-
84873574036
-
-
WO04022560A1 (2004) and WO04022560C2
-
Guzi, T.J., Paruch, K., Dwyer, M.P. Doll, R.J., Girijavallabhan, V.M., Dillard, L.W., Tran, V.D., He, Z.M., James, R.A., Park, H.: WO04022560A1 (2004) and WO04022560C2 (2005).
-
(2005)
-
-
Guzi, T.J.1
Paruch, K.2
Dwyer, M.P.3
Doll, R.J.4
Girijavallabhan, V.M.5
Dillard, L.W.6
Tran, V.D.7
He, Z.M.8
James, R.A.9
Park, H.10
-
74
-
-
84873586586
-
-
WO04022561A1
-
Guzi, T.J., Paruch, K., Dwyer, M.P. Doll, R.J., Girijavallabhan, V.M., Mallams, A., Alvarez, C.S., Keertikar, K.M., Rivera, J., Chan, T.-Y., Madison, V., Fischmann, T.O., Dillard, L.W., Tran, V.D., He, Z.M., James, R.A., Park, H., Paradkar, V.M., Hobbs, D.W.: WO04022561A1 (2004).
-
(2004)
-
-
Guzi, T.J.1
Paruch, K.2
Dwyer, M.P.3
Doll, R.J.4
Girijavallabhan, V.M.5
Mallams, A.6
Alvarez, C.S.7
Keertikar, K.M.8
Rivera, J.9
Chan, T.-Y.10
Madison, V.11
Fischmann, T.O.12
Dillard, L.W.13
Tran, V.D.14
He, Z.M.15
James, R.A.16
Park, H.17
Paradkar, V.M.18
Hobbs, D.W.19
-
75
-
-
84873579865
-
-
WO04026229A2 and WO04026229A3
-
Guzi, T.J., Paruch, K., Dwyer, M.P., Doll, R.J., Girijavallabhan, V.M., Alvarez, C.S., Chan, T.-Y., Knutson, C., Madison, V., Fischmann, T.O., Dillard, L.W., Tran, V.D., He, Z.M., James, R. A., Park, H.: WO04026229A2 and WO04026229A3 (2004).
-
(2004)
-
-
Guzi, T.J.1
Paruch, K.2
Dwyer, M.P.3
Doll, R.J.4
Girijavallabhan, V.M.5
Alvarez, C.S.6
Chan, T.-Y.7
Knutson, C.8
Madison, V.9
Fischmann, T.O.10
Dillard, L.W.11
Tran, V.D.12
He, Z.M.13
James, R.A.14
Park, H.15
-
76
-
-
84873607562
-
-
WO04026872
-
Dwyer, M.P., Guzi, T.J., Paruch, K., Doll, R.J., Keertikar, K.M., Girijavallabhan, V.M.: WO04026872 (2004).
-
(2004)
-
-
Dwyer, M.P.1
Guzi, T.J.2
Paruch, K.3
Doll, R.J.4
Keertikar, K.M.5
Girijavallabhan, V.M.6
-
77
-
-
84873600923
-
-
WO03051886A1 (2003) and WO03051886C1
-
Harris, P.A., Jung, D.K., Peel, M.R., Reno, M.J., Rheault, T.R., Stanford, J.B., Stevens, K.L., Veal, J.M.: WO03051886A1 (2003) and WO03051886C1 (2004).
-
(2004)
-
-
Harris, P.A.1
Jung, D.K.2
Peel, M.R.3
Reno, M.J.4
Rheault, T.R.5
Stanford, J.B.6
Stevens, K.L.7
Veal, J.M.8
-
79
-
-
84873605919
-
-
WO03078402A1
-
Damour, D., Carry, J.-C., Nemecek, P., Terrier, C., Nardi, F., Filoche, B., Cherrier, M.-P., Bezard, D.: WO03078402A1 (2003).
-
(2003)
-
-
Damour, D.1
Carry, J.-C.2
Nemecek, P.3
Terrier, C.4
Nardi, F.5
Filoche, B.6
Cherrier, M.-P.7
Bezard, D.8
-
80
-
-
84873604284
-
-
WO03101989A1
-
Ledford, B.E.: WO03101989A1 (2003).
-
(2003)
-
-
Ledford, B.E.1
-
81
-
-
84873574745
-
-
WO04014864A1
-
Berdini, V., Padova, A., Saxty, G., Woolford, A.J.-A., Wyatt, P.G.: WO04014864A1 (2004).
-
(2004)
-
-
Berdini, V.1
Padova, A.2
Saxty, G.3
Woolford, A.J.-A.4
Wyatt, P.G.5
-
82
-
-
84873597814
-
-
WO04014922A1
-
Berdini, V., Carr, M., Saxty, G., Woolford, A.J.-A., Wyatt, P.G.: WO04014922A1 (2004).
-
(2004)
-
-
Berdini, V.1
Carr, M.2
Saxty, G.3
Woolford, A.J.-A.4
Wyatt, P.G.5
-
84
-
-
84873601639
-
-
WO03062246A1
-
Repine, J.T.: WO03062246A1 (2003).
-
(2003)
-
-
Repine, J.T.1
-
85
-
-
84873602637
-
-
WO03076437A1
-
Lucking, U., Kruger, M., Jautelat, R., Prein, O., Siemeister, G., Ernst, A.: WO03076437A1 (2003).
-
(2003)
-
-
Lucking, U.1
Kruger, M.2
Jautelat, R.3
Prein, O.4
Siemeister, G.5
Ernst, A.6
-
86
-
-
84873596957
-
-
WO04009562A1
-
Kuo, G.-H., Deangelis, A., Wang, A., Zhang, Y., Emanuel, S.L., Middleton, S.A.: WO04009562A1 (2004).
-
(2004)
-
-
Kuo, G.-H.1
Deangelis, A.2
Wang, A.3
Zhang, Y.4
Emanuel, S.L.5
Middleton, S.A.6
-
88
-
-
84873584841
-
-
WO04004730A2 and WO04004730A3
-
Woolford, A.J.-A., Berdini, V., Oreilly, M., Padova, A., Saxty, G., Wyatt, P.G.: WO04004730A2 and WO04004730A3 (2004).
-
(2004)
-
-
Woolford, A.J.-A.1
Berdini, V.2
Oreilly, M.3
Padova, A.4
Saxty, G.5
Wyatt, P.G.6
-
89
-
-
0038394493
-
Novel pyrrolyllactone and pyrrolyllactame indolinones as potent cyclic-dependent kinase 2 inhibitors
-
Li X, Huang P, Cui JJ, Zhang J, Tang C. Novel pyrrolyllactone and pyrrolyllactame indolinones as potent cyclic-dependent kinase 2 inhibitors. Bioorg Med Chem Lett 2003; 13: 1939-1942.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 1939-1942
-
-
Li, X.1
Huang, P.2
Cui, J.J.3
Zhang, J.4
Tang, C.5
-
90
-
-
84873586992
-
-
WO04026829A2 and WO04026829A3
-
Kley, J., Heckel, A., Hilberg, F., Roth, G.J., Lehmann-Lintz, T., Lotz, R.R.H., Tontsch-Grunt, U., Van, M.J.C.A.: WO04026829A2 and WO04026829A3 (2004).
-
(2004)
-
-
Kley, J.1
Heckel, A.2
Hilberg, F.3
Roth, G.J.4
Lehmann-Lintz, T.5
Lotz, R.R.H.6
Tontsch-Grunt, U.7
Van, M.J.C.A.8
-
93
-
-
84873590174
-
-
WO03078647A2 and WO03078647A3
-
Haydar, S.N.: WO03078647A2 and WO03078647A3 (2003).
-
(2003)
-
-
Haydar, S.N.1
-
94
-
-
84873582178
-
-
WO04007498A2, WO04007498A3 and WO04007498C2
-
Lacrampe, J.F.A., Connors, R.W., Ho, C.Y., Richardson, A., Freyne, E.J.E., Buijnsters, P. J. J., Bakker, A.C.: WO04007498A2, WO04007498A3 and WO04007498C2 (2004).
-
(2004)
-
-
Lacrampe, J.F.A.1
Connors, R.W.2
Ho, C.Y.3
Richardson, A.4
Freyne, E.J.E.5
Buijnsters, P.J.J.6
Bakker, A.C.7
-
95
-
-
84873597958
-
-
WO04007499A1
-
Lacrampe, J.F.A., Connors, R.W., Ho, C.Y., Richardson, A., Freyne, E.J.E., Buijnsters, P.J.J., Bakker, A.C.: WO04007499A1 (2004).
-
(2004)
-
-
Lacrampe, J.F.A.1
Connors, R.W.2
Ho, C.Y.3
Richardson, A.4
Freyne, E.J.E.5
Buijnsters, P.J.J.6
Bakker, A.C.7
-
96
-
-
84873608135
-
-
WO04011465A1
-
Cannolly, C.J., Deur, C.J., Hamby, D.W., Hoyer, D.W.; Limberakis, C., Reed, J.E., Schroeder, M.C., Taylor, C.B.: WO04011465A1 (2004).
-
(2004)
-
-
Cannolly, C.J.1
Deur, C.J.2
Hamby, D.W.3
Hoyer, D.W.4
Limberakis, C.5
Reed, J.E.6
Schroeder, M.C.7
Taylor, C.B.8
-
97
-
-
11144354321
-
Imidazole[1,2-b]pyridazines: A potent and selective class of cyclin-dependent kinase inhibitors
-
Byth KF, Cooper C, Culshaw JD, et al. Imidazole[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors. Bioorganic and Med Chem Lett 2004; 14: 2249-52
-
(2004)
Bioorganic and Med Chem Lett
, vol.14
, pp. 2249-2252
-
-
Byth, K.F.1
Cooper, C.2
Culshaw, J.D.3
-
98
-
-
8744236193
-
Synthesis and biological evaluation of 1-Aryl-45-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases
-
Markwalder JA, Arnone MR, Benfield PA, et al. Synthesis and biological evaluation of 1-Aryl-45-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases. J Med Chem 2004; 47: 5894-11.
-
(2004)
J Med Chem
, vol.47
, pp. 5811-5894
-
-
Markwalder, J.A.1
Arnone, M.R.2
Benfield, P.A.3
-
99
-
-
20244366405
-
Pyrido[2,3-d]pyrimidin-7-ones as specific inhibitors of cyclic-dependent kinase 4
-
VanderWel SN, Harvey PL, McNamara DJ, et al. Pyrido[2,3-d]pyrimidin-7-ones as specific inhibitors of cyclic-dependent kinase 4. J Med Chem. 2005; 48: 2371-87.
-
(2005)
J Med Chem
, vol.48
, pp. 2371-2387
-
-
VanderWel, S.N.1
Harvey, P.L.2
McNamara, D.J.3
-
100
-
-
21244505487
-
1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent cyclic-dependent kinase inhibitors: Synthesis and evaluation of biological activities
-
Lin R, Connolly PJ, Huang S, et al. 1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent cyclic-dependent kinase inhibitors: Synthesis and evaluation of biological activities. J Med Chem 2005; 48: 4208-11.
-
(2005)
J Med Chem
, vol.48
, pp. 4208-4211
-
-
Lin, R.1
Connolly, P.J.2
Huang, S.3
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