Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II

Molecular Biology of the Cell

Volumn 7, Issue 4, 1996, Pages 505-513

  Leclerc, Vincent ^a   Tassan, Jean Pierre ^b   O'Farrell, Patrick H ^c   Nigg, Erich A ^d   Leopold, Pierre ^a  

^a CNRS   (France)

^b SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLINE; RNA POLYMERASE II;

ANIMAL CELL; ARTICLE; DROSOPHILA; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

ANIMALIA; EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0029880998     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.7.4.505     Document Type: Article

References (51)

1. Besse, S., Vigneron, M., Pichard, E., and Puvion-Dutilleuil, F. (1995). Synthesis and maturation of viral transcripts in herpes simplex virus type 1-infected HeLa cells: the role of interchromatin granules. Gene Expression 4, 143-161.
2. Brown, N.H., and Kafatos, F.C. (1988). Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203, 425-437.
3. Clarke, P.R. (1995). Cyclin-dependent kinases. CAK-handed kinase activation. Curr. Biol. 5, 40-42.
4. Conaway, R.C., and Conaway, J.W. (1989). An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters. Proc. Natl. Acad. Sci. USA 86, 7356-7360.
5. Dessen, P., Fondrat, C., Valencien, C., and Mugnier, C. (1990). BISANCE: a French service for access to biomolecular sequence databases. Cabios 6, 355-356.
6. Ducommun, B., Brambilla, P., and Draetta, G. (1991). Mutations at sites involved in Suc1 binding inactivate Cdc2. Mol. Cell. Biol. 11, 6177-6184.
7. Edgar, B.A., Sprenger, F., Duronio, R.J., Leopold, P., and O'Farrell, P.H. (1994). Distinct molecular mechanisms regulate cell cycle timing at successive stages of Drosophila embryogenesis. Genes Dev. 8, 440-452.
8. Endicott, J.A., Nurse, P., and Johnson, L.N. (1994). Mutational analysis supports a structural model for the cell cycle protein kinase p34. Protein Eng. 7, 243-253.
9. Feaver, W.J., Gileadi, O., Li, Y., and Kornberg, R.D. (1991). CTD kinase associated with yeast RNA polymerase II initiation factor b. Cell 67, 1223-1230.
10. Feaver, W.J., Svejstrup, J.Q., Henry, N.L., and Kornberg, R.D. (1994). Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK. Cell 79, 1103-1109.
11. Fesquet, D., Labbe, J., Derancourt, J., Capony, J., Galas, S., Girard, F., Lorca, T., Shuttleworth, J., Doree, M., and Cavadore, J. (1993). The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues. EMBO J. 12, 3111-3121.
12. Fisher, R.P., and Morgan, D.O. (1994). A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase. Cell 78, 713-724.
13. Hengartner, C.J., Thompson, C.M., Zhang, J., Chao, D.M., Liao, S.M., Koleske, A.J., Okamura, S., and Young, R.A. (1995). Association of an activator with an RNA polymerase II holoenzyme. Genes Dev. 9, 897-910.
14. Hirst, K., Fisher, F., McAndrew, P.C., and Goding, C.R. (1994). The transcription factor, the Cdk, its cyclin and their regulator: directing the transcriptional response to a nutritional signal. EMBO J. 13, 5410-5420.
15. Jeffrey, P.D., Russo, A.A., Polyak, C., Gibbs, E., Hurwitz, J., Massagué, J., and Pavletich, N.P. (1995). Mechanism of CDK activation revealed by the structure of a cyclin A-CDK2 complex. Nature 376, 313-320.
16. Kaffman, A., Herskowitz, I., Tjian, R., and O'Shea, E.K. (1994). Phosphorylation of the transcription factor PHO4 by a cydin-CDK complex, PHO80-PHO85. Science 263, 1153-1156.
17. Kim, Y.-J., Bjorklund, S., Li, Y., Sayre, M.H., and Kornberg, R.D. (1994). A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat of RNA polymerase II. Cell 77, 599-608.
18. King, R.W., Jackson, P.K., and Kirschner, M.W. (1994). Mitosis in transition. Cell 79, 563-571.
19. Koleske, A.J., Buratowski, S., Nonet, M., and Young, R.A. (1992). A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID. Cell 69, 883-894.
20. Koleske, A.J., and Young, R.A. (1994). An RNA polymerase II holoenzyme responsive to activators. Nature 368, 466-469.
21. Koleske, A.J., and Young, R.A. (1995). The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem. Sci. 20, 113-116.
22. Kramer, A., Haars, R., Kabisch, R., Will, H., Bautz, F.A., and Bautz, E.K. (1980). Monoclonal antibody directed against RNA polymerase II of Drosophila melanogaster. Mol. Gen. Genet. 180, 193-199.
23. Kuchin, S., Yeghiayan, P., and Carlson, M. (1995). Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. Proc. Natl. Acad. Sci. USA 92, 4006-4010.
24. Lahue, E.E., Smith, A.V., and Orr-Weaver, T.L. (1991). A novel cyclin gene from Drosophila complements CLN function in yeast. Genes Dev. 5, 2166-2175.
25. Lee, J.M., and Greenleaf, A.L. (1989). A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II. Proc. Natl. Acad. Sci. USA 86, 3624-3628.
26. Lehner, C., and O'Farrell, P.H. (1990). Drosophila cdc2 homologs: a functional homolog is coexpressed with a cognate variant. EMBO J. 9, 3573-3581.
27. Leopold, P., and O'Farrell, P.H. (1991). An evolutionarily conserved cyclin homolog from Drosophila rescues yeast deficient in G1 cyclins. Cell 66, 1207-1216.
28. Lew, D.J., Dulic, V., and Reed, S. (1991). Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. Cell 66, 1197-1206.
29. Liao, S.M., Zhang, J., Jeffery, D.A., Koleske, A.J., Thompson, C.M., Chao, D.M., Viljoen, M., van, V.H., and Young, R.A. (1995). A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374, 193-196.
30. Lu, H., Zawel, L., Fisher, L., Egly, J.M., and Reinberg, D. (1992). Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II. Nature 358, 641-645.
31. Makela, T.P., Tassan, J.P., Nigg, E.A., Frutiger, S., Hughes, G.J., and Weinberg, R.A. (1994). A cyclin associated with the CDK-activating kinase MO15. Nature 373, 254-257.
32. Morgan, D.O. (1995). Principles of CDK regulation. Nature 376, 131-134.
33. Nigg, E.A. (1995). Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. BioEssays 17, 471-480.
34. Nurse, P. (1994). Ordering S phase and M phase in the cell cycle. Cell 79, 547-550.
35. Poon, R., Yamashita, K., Adamczewski, J., Hunt, T., and Shuttleworth, J. (1993). The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2. EMBO J. 22, 3123-3132.
36. Rosenblatt, J., Gu, Y., and Morgan, D.O. (1992). Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. Proc. Natl. Acad. Sci. USA 89, 2824-2828.
37. Roy, R., Adamczewski, J.P., Seroz, T., Vermeulen, W., Tassan, J.P., Schaeffer, L., Nigg, E.A., Hoeijmakers, J.H., and Egly, J.M. (1994). The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell 79, 1093-1101.
38. Schneider, K.R., Smith, R.L., and O'Shea, E.K. (1994). Phosphate-regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81. Science 266, 122-126.
39. Schultz, S.J., and Nigg, E.A. (1993). Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergilus nidulans. Cell Growth Differ. 4, 821-830.
40. Serizawa, H., Makela, T.P., Conaway, J.W., Conaway, R.C., Weinberg, R.A., and Young, R.A. (1995). Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature 374, 280-282.
41. Sherr, C.J. (1994). G1 phase progression: cycling on cue. Cell 79, 551-555.
42. Shiekhattar, R., Mermelstein, F., Fisher, R.P., Drapkin, R., Dynlacht, B., Wessling, H.C., Morgan, D.O., and Reinberg, D. (1995). Cdk-activating kinase complex is a component of human transcription factor TFIIH. Nature 374, 283-287.
43. Smith, D.B., and Johnson, K.S. (1988). Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67, 31-40.
44. cdc2-activating kinase, contains a protein identical or closely related to p40MO15. EMBO J. 22, 3133-3142.
45. Sprenger, F., Trosclair, M.M., and Morrison, D.K. (1993). Biochemical analysis of torso and D-raf during Drosophila embryogenesis: implications for terminal signal transduction. Mol. Cell Biol. 23, 1163-1172.
46. Surosky, R.T., Strich, R., and Esposito, R.E. (1994). The yeast UME5 gene regulates the stability of meiotic mRNAs in response to glucose. Mol. Cell Biol. 24, 3446-3458.
47. Tassan, J.-P., Jaquenoud, M., Léopold, P., Schultz, S.J., and Nigg, E.A. (1995). Identification of human CDK8, a protein kinase partner for cyclin C and potential homolog of yeast SRB10. Proc. Natl. Acad. Sci. USA 92, 8871-8875.
48. Tassan, J.-P., Schultz, S.J., Bartek, J., and Nigg, E.A. (1994). Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase). J. Cell Biol. 227, 467-478.
49. Thompson, C.M., Koleske, A.J., Chao, D.M., and Young, R.A. (1993). A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73, 1361-1375.
50. Wahi, M., and Johnson, A.D. (1995). Identification of genes required for α2 repression in Saccharomyces cerevisiae. Genetics 240, 79-90.
51. Yoshinaga, S.K., and Yamamoto, K.R. (1991). Signaling and regulation by a mammalian glucocorticoid receptor in Drosophila cells. Mol. Endocrinol. 5, 844-853.