메뉴 건너뛰기




Volumn 129, Issue 3, 2008, Pages 109-119

Identification of p53-dependent genes potentially involved in UVB-mediated premature senescence of human skin fibroblasts using siRNA technology

Author keywords

DNA array; Fibroblasts; Gene expression; p53; Senescence; UVB

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GELATINASE A; MESSENGER RNA; PROTEIN P53; SMALL INTERFERING RNA; SOMATOMEDIN BINDING PROTEIN 3; TRANSFORMING GROWTH FACTOR BETA1;

EID: 38949144420     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2007.10.014     Document Type: Article
Times cited : (17)

References (71)
  • 1
    • 33846657255 scopus 로고    scopus 로고
    • The p16INK4a tumor suppressor controls p21WAF1 induction in response to ultraviolet light
    • Al-Mohanna M.A., Al-Khalaf H.H., Al-Yousef N., and Aboussekhra A. The p16INK4a tumor suppressor controls p21WAF1 induction in response to ultraviolet light. Nucleic Acids Res. 35 (2007) 223-233
    • (2007) Nucleic Acids Res. , vol.35 , pp. 223-233
    • Al-Mohanna, M.A.1    Al-Khalaf, H.H.2    Al-Yousef, N.3    Aboussekhra, A.4
  • 2
    • 0030477686 scopus 로고    scopus 로고
    • Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
    • Alcorta D.A., Xiong Y., Phelps D., Hannon G., Beach D., and Barrett J.C. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 13742-13747
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 13742-13747
    • Alcorta, D.A.1    Xiong, Y.2    Phelps, D.3    Hannon, G.4    Beach, D.5    Barrett, J.C.6
  • 5
    • 0034656409 scopus 로고    scopus 로고
    • Glyceraldehyde-3-phosphate dehydrogenase and apoptosis
    • Berry M.D., and Boulton A.A. Glyceraldehyde-3-phosphate dehydrogenase and apoptosis. J. Neurosci. Res. 60 (2000) 150-154
    • (2000) J. Neurosci. Res. , vol.60 , pp. 150-154
    • Berry, M.D.1    Boulton, A.A.2
  • 6
    • 34547955129 scopus 로고    scopus 로고
    • The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype
    • Borlon C., Debacq-Chainiaux F., Hinrichs C., Scharffetter-Kochanek K., Toussaint O., and Wlaschek M. The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype. Exp. Gerontol. 42 (2007) 911-923
    • (2007) Exp. Gerontol. , vol.42 , pp. 911-923
    • Borlon, C.1    Debacq-Chainiaux, F.2    Hinrichs, C.3    Scharffetter-Kochanek, K.4    Toussaint, O.5    Wlaschek, M.6
  • 7
    • 0034595212 scopus 로고    scopus 로고
    • Switzerland, September 18-22, 1999
    • Brack C., Lithgow G., Osiewacz H., and Toussaint O. EMBO Workshop Report: Molecular and Cellular Gerontology Serpiano. Switzerland, September 18-22, 1999. Embo J. 19 (2000) 1929-1934
    • (2000) Embo J. , vol.19 , pp. 1929-1934
    • Brack, C.1    Lithgow, G.2    Osiewacz, H.3    Toussaint, O.4
  • 10
    • 0035500487 scopus 로고    scopus 로고
    • Cellular senescence as a tumor-suppressor mechanism
    • Campisi J. Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol. 11 (2001) S27-S31
    • (2001) Trends Cell Biol. , vol.11
    • Campisi, J.1
  • 11
    • 0028345161 scopus 로고
    • Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
    • Chen Q., and Ames B.N. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 4130-4134
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 4130-4134
    • Chen, Q.1    Ames, B.N.2
  • 12
    • 0033232529 scopus 로고    scopus 로고
    • Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53
    • Chen R.W., Saunders P.A., Wei H., Li Z., Seth P., and Chuang D.M. Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53. J. Neurosci. 19 (1999) 9654-9662
    • (1999) J. Neurosci. , vol.19 , pp. 9654-9662
    • Chen, R.W.1    Saunders, P.A.2    Wei, H.3    Li, Z.4    Seth, P.5    Chuang, D.M.6
  • 17
    • 34247526303 scopus 로고    scopus 로고
    • Short-hairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesis
    • Di Fulvio M., Henkels K.M., and Gomez-Cambronero J. Short-hairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesis. Biochem. Biophys. Res. Commun. 357 (2007) 737-742
    • (2007) Biochem. Biophys. Res. Commun. , vol.357 , pp. 737-742
    • Di Fulvio, M.1    Henkels, K.M.2    Gomez-Cambronero, J.3
  • 20
    • 15244346075 scopus 로고    scopus 로고
    • Frequent overexpression of cyclin D2/cyclin-dependent kinase 4 in Wilms' tumor
    • Faussillon M., Monnier L., Junien C., and Jeanpierre C. Frequent overexpression of cyclin D2/cyclin-dependent kinase 4 in Wilms' tumor. Cancer Lett. 221 (2005) 67-75
    • (2005) Cancer Lett. , vol.221 , pp. 67-75
    • Faussillon, M.1    Monnier, L.2    Junien, C.3    Jeanpierre, C.4
  • 21
    • 0033813462 scopus 로고    scopus 로고
    • p53-Dependent induction of heat shock protein 27 (HSP27) expression
    • Gao C., Zou Z., Xu L., Moul J., Seth P., and Srivastava S. p53-Dependent induction of heat shock protein 27 (HSP27) expression. Int. J. Cancer 88 (2000) 191-194
    • (2000) Int. J. Cancer , vol.88 , pp. 191-194
    • Gao, C.1    Zou, Z.2    Xu, L.3    Moul, J.4    Seth, P.5    Srivastava, S.6
  • 23
    • 10844235689 scopus 로고    scopus 로고
    • Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes
    • Gillet J.P., Efferth T., Steinbach D., Hamels J., de Longueville F., Bertholet V., and Remacle J. Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes. Cancer Res. 64 (2004) 8987-8993
    • (2004) Cancer Res. , vol.64 , pp. 8987-8993
    • Gillet, J.P.1    Efferth, T.2    Steinbach, D.3    Hamels, J.4    de Longueville, F.5    Bertholet, V.6    Remacle, J.7
  • 24
    • 0021287698 scopus 로고
    • Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines
    • Green L.M., Reade J.L., and Ware C.F. Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines. J. Immunol. Methods 70 (1984) 257-268
    • (1984) J. Immunol. Methods , vol.70 , pp. 257-268
    • Green, L.M.1    Reade, J.L.2    Ware, C.F.3
  • 25
    • 33751084057 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling
    • Grimberg A., Coleman C.M., Shi Z., Burns T.F., MacLachlan T.K., Wang W., and El-Deiry W.S. Insulin-like growth factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling. Cancer Biol. Ther. 5 (2006) 1408-1414
    • (2006) Cancer Biol. Ther. , vol.5 , pp. 1408-1414
    • Grimberg, A.1    Coleman, C.M.2    Shi, Z.3    Burns, T.F.4    MacLachlan, T.K.5    Wang, W.6    El-Deiry, W.S.7
  • 26
    • 0027528673 scopus 로고
    • High levels of p53 protein in UV-irradiated normal human skin
    • Hall P.A., McKee P.H., Menage H.D., Dover R., and Lane D.P. High levels of p53 protein in UV-irradiated normal human skin. Oncogene 8 (1993) 203-207
    • (1993) Oncogene , vol.8 , pp. 203-207
    • Hall, P.A.1    McKee, P.H.2    Menage, H.D.3    Dover, R.4    Lane, D.P.5
  • 27
    • 0029670840 scopus 로고    scopus 로고
    • Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
    • Hara E., Smith R., Parry D., Tahara H., Stone S., and Peters G. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol. 16 (1996) 859-867
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 859-867
    • Hara, E.1    Smith, R.2    Parry, D.3    Tahara, H.4    Stone, S.5    Peters, G.6
  • 28
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell L.H., and Kastan M.B. Cell cycle control and cancer. Science 266 (1994) 1821-1828
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 29
    • 0033541163 scopus 로고    scopus 로고
    • Attenuation of NF-kappaB signaling response to UVB light during cellular senescence
    • Helenius M., Makelainen L., and Salminen A. Attenuation of NF-kappaB signaling response to UVB light during cellular senescence. Exp. Cell Res. 248 (1999) 194-202
    • (1999) Exp. Cell Res. , vol.248 , pp. 194-202
    • Helenius, M.1    Makelainen, L.2    Salminen, A.3
  • 31
    • 33745612464 scopus 로고    scopus 로고
    • Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity
    • Jackson A.L., Burchard J., Schelter J., Chau B.N., Cleary M., Lim L., and Linsley P.S. Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity. RNA 12 (2006) 1179-1187
    • (2006) RNA , vol.12 , pp. 1179-1187
    • Jackson, A.L.1    Burchard, J.2    Schelter, J.3    Chau, B.N.4    Cleary, M.5    Lim, L.6    Linsley, P.S.7
  • 33
    • 0027587414 scopus 로고
    • The induction of gene expression in mammalian cells by radiation
    • Keyse S.M. The induction of gene expression in mammalian cells by radiation. Semin. Cancer Biol. 4 (1993) 119-128
    • (1993) Semin. Cancer Biol. , vol.4 , pp. 119-128
    • Keyse, S.M.1
  • 34
    • 2442423343 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor, a biomarker in senescence of human diploid fibroblasts, is up-regulated by a transforming growth factor-beta-mediated signaling pathway
    • Kim K.H., Park G.T., Lim Y.B., Rue S.W., Jung J.C., Sonn J.K., Bae Y.S., Park J.W., and Lee Y.S. Expression of connective tissue growth factor, a biomarker in senescence of human diploid fibroblasts, is up-regulated by a transforming growth factor-beta-mediated signaling pathway. Biochem. Biophys. Res. Commun. 318 (2004) 819-825
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 819-825
    • Kim, K.H.1    Park, G.T.2    Lim, Y.B.3    Rue, S.W.4    Jung, J.C.5    Sonn, J.K.6    Bae, Y.S.7    Park, J.W.8    Lee, Y.S.9
  • 35
    • 0029972806 scopus 로고    scopus 로고
    • p53: puzzle and paradigm
    • Ko L.J., and Prives C. p53: puzzle and paradigm. Genes Dev. 10 (1996) 1054-1072
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 37
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine A.J. p53, the cellular gatekeeper for growth and division. Cell 88 (1997) 323-331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 38
    • 33646807832 scopus 로고    scopus 로고
    • The P53 pathway: what questions remain to be explored?
    • Levine A.J., Hu W., and Feng Z. The P53 pathway: what questions remain to be explored?. Cell Death Differ. 13 (2006) 1027-1036
    • (2006) Cell Death Differ. , vol.13 , pp. 1027-1036
    • Levine, A.J.1    Hu, W.2    Feng, Z.3
  • 39
    • 0031818021 scopus 로고    scopus 로고
    • p53-dependent DNA repair and apoptosis respond differently to high- and low-dose ultraviolet radiation
    • Li G., and Ho V.C. p53-dependent DNA repair and apoptosis respond differently to high- and low-dose ultraviolet radiation. Br. J. Dermatol. 139 (1998) 3-10
    • (1998) Br. J. Dermatol. , vol.139 , pp. 3-10
    • Li, G.1    Ho, V.C.2
  • 40
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
    • Lu X., and Lane D.P. Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?. Cell 75 (1993) 765-778
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.P.2
  • 41
    • 0029952441 scopus 로고    scopus 로고
    • In vivo ubiquitination and proteasome-mediated degradation of p53(1)
    • Maki C.G., Huibregtse J.M., and Howley P.M. In vivo ubiquitination and proteasome-mediated degradation of p53(1). Cancer Res. 56 (1996) 2649-2654
    • (1996) Cancer Res. , vol.56 , pp. 2649-2654
    • Maki, C.G.1    Huibregtse, J.M.2    Howley, P.M.3
  • 42
    • 0033552638 scopus 로고    scopus 로고
    • Twenty years of p53 research: structural and functional aspects of the p53 protein
    • May P., and May E. Twenty years of p53 research: structural and functional aspects of the p53 protein. Oncogene 18 (1999) 7621-7636
    • (1999) Oncogene , vol.18 , pp. 7621-7636
    • May, P.1    May, E.2
  • 43
    • 34547183458 scopus 로고    scopus 로고
    • MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2
    • Mendes O., Kim H.T., Lungu G., and Stoica G. MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2. Clin. Exp. Metastasis (2007)
    • (2007) Clin. Exp. Metastasis
    • Mendes, O.1    Kim, H.T.2    Lungu, G.3    Stoica, G.4
  • 44
    • 0026744250 scopus 로고
    • Cell cycle regulation and the p53 tumor suppressor protein
    • Mercer W.E. Cell cycle regulation and the p53 tumor suppressor protein. Crit. Rev. Eukaryot. Gene Expr 2 (1992) 251-263
    • (1992) Crit. Rev. Eukaryot. Gene Expr , vol.2 , pp. 251-263
    • Mercer, W.E.1
  • 46
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T., and Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80 (1995) 293-299
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 47
    • 33748747409 scopus 로고    scopus 로고
    • Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression
    • Nair R.R., Solway J., and Boyd D.D. Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression. J. Biol. Chem. 281 (2006) 26424-26436
    • (2006) J. Biol. Chem. , vol.281 , pp. 26424-26436
    • Nair, R.R.1    Solway, J.2    Boyd, D.D.3
  • 48
    • 21244445454 scopus 로고    scopus 로고
    • Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays
    • Pascal T., Debacq-Chainiaux F., Chretien A., Bastin C., Dabee A.F., Bertholet V., Remacle J., and Toussaint O. Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays. FEBS Lett. 579 (2005) 3651-3659
    • (2005) FEBS Lett. , vol.579 , pp. 3651-3659
    • Pascal, T.1    Debacq-Chainiaux, F.2    Chretien, A.3    Bastin, C.4    Dabee, A.F.5    Bertholet, V.6    Remacle, J.7    Toussaint, O.8
  • 50
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29 (2001) e45
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 56
    • 0345167184 scopus 로고    scopus 로고
    • Alterations of pRb1-cyclin D1-cdk4/6-p16(INK4A) pathway in endometrial carcinogenesis
    • Semczuk A., and Jakowicki J.A. Alterations of pRb1-cyclin D1-cdk4/6-p16(INK4A) pathway in endometrial carcinogenesis. Cancer Lett. 203 (2004) 1-12
    • (2004) Cancer Lett. , vol.203 , pp. 1-12
    • Semczuk, A.1    Jakowicki, J.A.2
  • 57
    • 0742288682 scopus 로고    scopus 로고
    • Expression of the cell-cycle regulatory proteins (pRb, cyclin D1, p16INK4A and cdk4) in human endometrial cancer: correlation with clinicopathological features
    • Semczuk A., Miturski R., Skomra D., and Jakowicki J.A. Expression of the cell-cycle regulatory proteins (pRb, cyclin D1, p16INK4A and cdk4) in human endometrial cancer: correlation with clinicopathological features. Arch. Gynecol. Obstet. 269 (2004) 104-110
    • (2004) Arch. Gynecol. Obstet. , vol.269 , pp. 104-110
    • Semczuk, A.1    Miturski, R.2    Skomra, D.3    Jakowicki, J.A.4
  • 58
    • 33751301109 scopus 로고    scopus 로고
    • Clusterin and DNA repair: a new function in cancer for a key player in apoptosis and cell cycle control
    • Shannan B., Seifert M., Boothman D.A., Tilgen W., and Reichrath J. Clusterin and DNA repair: a new function in cancer for a key player in apoptosis and cell cycle control. J. Mol. Histol. 37 (2006) 183-188
    • (2006) J. Mol. Histol. , vol.37 , pp. 183-188
    • Shannan, B.1    Seifert, M.2    Boothman, D.A.3    Tilgen, W.4    Reichrath, J.5
  • 60
    • 0029959697 scopus 로고    scopus 로고
    • Estimates of ozone depletion and skin cancer incidence to examine the Vienna Convention achievements
    • Slaper H., Velders G.J., Daniel J.S., de Gruijl F.R., and van der Leun J.C. Estimates of ozone depletion and skin cancer incidence to examine the Vienna Convention achievements. Nature 384 (1996) 256-258
    • (1996) Nature , vol.384 , pp. 256-258
    • Slaper, H.1    Velders, G.J.2    Daniel, J.S.3    de Gruijl, F.R.4    van der Leun, J.C.5
  • 61
    • 4644336002 scopus 로고    scopus 로고
    • Dose and dose-rate effects of low-dose ionizing radiation on activation of Trp53 in immortalized murine cells
    • Sugihara T., Magae J., Wadhwa R., Kaul S.C., Kawakami Y., Matsumoto T., and Tanaka K. Dose and dose-rate effects of low-dose ionizing radiation on activation of Trp53 in immortalized murine cells. Radiat. Res. 162 (2004) 296-307
    • (2004) Radiat. Res. , vol.162 , pp. 296-307
    • Sugihara, T.1    Magae, J.2    Wadhwa, R.3    Kaul, S.C.4    Kawakami, Y.5    Matsumoto, T.6    Tanaka, K.7
  • 62
    • 0036829661 scopus 로고    scopus 로고
    • Clusterin/apolipoprotein J in human aging and cancer
    • Trougakos I.P., and Gonos E.S. Clusterin/apolipoprotein J in human aging and cancer. Int. J. Biochem. Cell Biol. 34 (2002) 1430-1448
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 1430-1448
    • Trougakos, I.P.1    Gonos, E.S.2
  • 63
    • 31944436913 scopus 로고    scopus 로고
    • Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: functional similarity to the human disease and identification of prospective tumoral markers and targets
    • Urzua U., Roby K.F., Gangi L.M., Cherry J.M., Powell J.I., and Munroe D.J. Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: functional similarity to the human disease and identification of prospective tumoral markers and targets. J. Cell Physiol. 206 (2006) 594-602
    • (2006) J. Cell Physiol. , vol.206 , pp. 594-602
    • Urzua, U.1    Roby, K.F.2    Gangi, L.M.3    Cherry, J.M.4    Powell, J.I.5    Munroe, D.J.6
  • 68
    • 0033634878 scopus 로고    scopus 로고
    • JunD protects cells from p53-dependent senescence and apoptosis
    • Weitzman J.B., Fiette L., Matsuo K., and Yaniv M. JunD protects cells from p53-dependent senescence and apoptosis. Mol. Cell 6 (2000) 1109-1119
    • (2000) Mol. Cell , vol.6 , pp. 1109-1119
    • Weitzman, J.B.1    Fiette, L.2    Matsuo, K.3    Yaniv, M.4
  • 69
    • 0035893746 scopus 로고    scopus 로고
    • Expression of Id helix-loop-helix proteins in colorectal adenocarcinoma correlates with p53 expression and mitotic index
    • Wilson J.W., Deed R.W., Inoue T., Balzi M., Becciolini A., Faraoni P., Potten C.S., and Norton J.D. Expression of Id helix-loop-helix proteins in colorectal adenocarcinoma correlates with p53 expression and mitotic index. Cancer Res. 61 (2001) 8803-8810
    • (2001) Cancer Res. , vol.61 , pp. 8803-8810
    • Wilson, J.W.1    Deed, R.W.2    Inoue, T.3    Balzi, M.4    Becciolini, A.5    Faraoni, P.6    Potten, C.S.7    Norton, J.D.8
  • 70
    • 33750977265 scopus 로고    scopus 로고
    • Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts
    • Zdanov S., Debacq-Chainiaux F., Remacle J., and Toussaint O. Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts. FEBS Lett. 580 (2006) 6455-6463
    • (2006) FEBS Lett. , vol.580 , pp. 6455-6463
    • Zdanov, S.1    Debacq-Chainiaux, F.2    Remacle, J.3    Toussaint, O.4
  • 71
    • 0028125271 scopus 로고
    • Mouse p53 represses the rat brain creatine kinase gene but activates the rat muscle creatine kinase gene
    • Zhao J., Schmieg F.I., Simmons D.T., and Molloy G.R. Mouse p53 represses the rat brain creatine kinase gene but activates the rat muscle creatine kinase gene. Mol. Cell. Biol. 14 (1994) 8483-8492
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8483-8492
    • Zhao, J.1    Schmieg, F.I.2    Simmons, D.T.3    Molloy, G.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.