Expression of connective tissue growth factor, a biomarker in senescence of human diploid fibroblasts, is up-regulated by a transforming growth factor-β-mediated signaling pathway

Biochemical and Biophysical Research Communications

Volumn 318, Issue 4, 2004, Pages 819-825

  Kim, Kook Hee ^a   Park, Geun Tae ^a   Lim, Young Bin ^a   Rue, Seok Woo ^a   Jung, Jae Chang ^a   Sonn, Jong Kyung ^a   Bae, Young Seuk ^a   Park, Jeen Woo ^a   Lee, Young Sup ^a  

^a Kyungpook National University   (South Korea)

Author keywords

CTGF; Human diploid fibroblasts; Senescence; TGF

Indexed keywords

BETA GALACTOSIDASE; BIOLOGICAL MARKER; CONNECTIVE TISSUE GROWTH FACTOR; HYDROGEN PEROXIDE; PROTEIN P21; PROTEIN P53; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL TISSUE; ARTICLE; CELL DIVISION; CELL STIMULATION; CONTROLLED STUDY; DIPLOIDY; ENZYME ACTIVITY; FIBROBLAST; GEL; HUMAN; HUMAN CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; CELL AGING; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DIPLOIDY; DNA-BINDING PROTEINS; ETHANOL; FIBROBLASTS; GALACTOSIDASES; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMAD PROTEINS; TERT-BUTYLHYDROPEROXIDE; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 2442423343     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.04.108     Document Type: Article

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