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Volumn 153, Issue 3, 2008, Pages 609-619

Activities of mixed NOP and μ-opioid receptor ligands

Author keywords

Antinociception; Buprenorphine; Mouse vas deferens; N OFQ; Nociceptin; NOP; Opioid receptor

Indexed keywords

BUPRENORPHINE; G PROTEIN COUPLED RECEPTOR; LIGAND; METHOCLOCINNAMOX; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALOXONE; NOCICEPTIN; NOP RECEPTOR; PARTIAL AGONIST; SR 14148; SR 14150; SR 16430; SR 16435; SR 16476; UNCLASSIFIED DRUG;

EID: 38849180176     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707598     Document Type: Article
Times cited : (56)

References (69)
  • 1
    • 0030734901 scopus 로고    scopus 로고
    • Relationship between binding affinity and functional activity of nociceptin/orphanin FQ
    • Adapa ID, Toll L (1997). Relationship between binding affinity and functional activity of nociceptin/orphanin FQ. Neuropeptides 31: 403-408.
    • (1997) Neuropeptides , vol.31 , pp. 403-408
    • Adapa, I.D.1    Toll, L.2
  • 2
    • 0029989011 scopus 로고    scopus 로고
    • Determination of activity for nociceptin in the mouse vas deferens
    • Berzetei-Gurske IP, Schwartz RW, Toll L (1996). Determination of activity for nociceptin in the mouse vas deferens. Eur J Pharmacol 302: R1-R2.
    • (1996) Eur J Pharmacol , vol.302
    • Berzetei-Gurske, I.P.1    Schwartz, R.W.2    Toll, L.3
  • 3
    • 0033821875 scopus 로고    scopus 로고
    • Agonistic effects of the opioid buprenorphine on the nociceptin/OFQ receptor
    • Bloms-Funke P, Gillen C, Schuettler AJ, Wnendt S (2000). Agonistic effects of the opioid buprenorphine on the nociceptin/OFQ receptor. Peptides 21: 1141-1146.
    • (2000) Peptides , vol.21 , pp. 1141-1146
    • Bloms-Funke, P.1    Gillen, C.2    Schuettler, A.J.3    Wnendt, S.4
  • 4
    • 0028284167 scopus 로고
    • Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type
    • Bunzow JR, Saez C, Mortrud M, Bouvier C, Williams JT, Low M et al. (1994). Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type. FEBS Lett 347: 284-288.
    • (1994) FEBS Lett , vol.347 , pp. 284-288
    • Bunzow, J.R.1    Saez, C.2    Mortrud, M.3    Bouvier, C.4    Williams, J.T.5    Low, M.6
  • 5
    • 0033821777 scopus 로고    scopus 로고
    • Species differences in the efficacy of compounds at the nociceptin receptor (ORL1)
    • Burnside JL, Rodriguez L, Toll L (2000). Species differences in the efficacy of compounds at the nociceptin receptor (ORL1). Peptides 21: 1147-1154.
    • (2000) Peptides , vol.21 , pp. 1147-1154
    • Burnside, J.L.1    Rodriguez, L.2    Toll, L.3
  • 6
    • 0031577964 scopus 로고    scopus 로고
    • Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids
    • Butour JL, Moisand C, Mazarguil H, Mollereau C, Meunier JC (1997). Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids. Eur J Pharmacol 321: 97-103.
    • (1997) Eur J Pharmacol , vol.321 , pp. 97-103
    • Butour, J.L.1    Moisand, C.2    Mazarguil, H.3    Mollereau, C.4    Meunier, J.C.5
  • 8
    • 0034101842 scopus 로고    scopus 로고
    • Characterization of [Nphe(1)]nociceptin(1-13)NH(2), a new selective nociceptin receptor antagonist
    • Calo G, Guerrini R, Bigoni R, Rizzi A, Marzola G, Okawa H et al. (2000). Characterization of [Nphe(1)]nociceptin(1-13)NH(2), a new selective nociceptin receptor antagonist. Br J Pharmacol 129: 1183-1193.
    • (2000) Br J Pharmacol , vol.129 , pp. 1183-1193
    • Calo, G.1    Guerrini, R.2    Bigoni, R.3    Rizzi, A.4    Marzola, G.5    Okawa, H.6
  • 13
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (I50) of an enzymatic reaction
    • Cheng Y-C, Prusoff WH (1973). Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol 22: 3099-3108.
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.-C.1    Prusoff, W.H.2
  • 14
    • 33745258231 scopus 로고    scopus 로고
    • Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance
    • Chung S, Pohl S, Zeng J, Civelli O, Reinscheid RK (2006). Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance. J Pharmacol Exp Ther 318: 262-267.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 262-267
    • Chung, S.1    Pohl, S.2    Zeng, J.3    Civelli, O.4    Reinscheid, R.K.5
  • 15
  • 16
    • 1642267207 scopus 로고    scopus 로고
    • Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats
    • Ciccocioppo R, Economidou D, Fedeli A, Angeletti S, Weiss F, Heilig M et al. (2004). Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats. Psychopharmacology (Berl) 172: 170-178.
    • (2004) Psychopharmacology (Berl) , vol.172 , pp. 170-178
    • Ciccocioppo, R.1    Economidou, D.2    Fedeli, A.3    Angeletti, S.4    Weiss, F.5    Heilig, M.6
  • 17
    • 33845188832 scopus 로고    scopus 로고
    • Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system
    • Ciccocioppo R, Economidou D, Rimondini R, Sommer W, Massi M, Heilig M (2007). Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system. Biol Psychiatry 61: 4-12.
    • (2007) Biol Psychiatry , vol.61 , pp. 4-12
    • Ciccocioppo, R.1    Economidou, D.2    Rimondini, R.3    Sommer, W.4    Massi, M.5    Heilig, M.6
  • 18
    • 0017756322 scopus 로고
    • Agonist and antagonist properties of buprenorphine, a new antinociceptive agent
    • Cowan A, Lewis JW, Macfarlane IR (1977). Agonist and antagonist properties of buprenorphine, a new antinociceptive agent. Br J Pharmacol 60: 537-545.
    • (1977) Br J Pharmacol , vol.60 , pp. 537-545
    • Cowan, A.1    Lewis, J.W.2    Macfarlane, I.R.3
  • 19
    • 0034920548 scopus 로고    scopus 로고
    • Pharmacological characterization of the novel nonpeptide orphanin FQ/nociceptin receptor agonist Ro 64-6198: Rapid and reversible desensitization of the ORL1 receptor in vitro and lack of tolerance in vivo
    • Dautzenberg FM, Wichmann J, Higelin J, Py-Lang G, Kratzeisen C, Malherbe P et al. (2001). Pharmacological characterization of the novel nonpeptide orphanin FQ/nociceptin receptor agonist Ro 64-6198: rapid and reversible desensitization of the ORL1 receptor in vitro and lack of tolerance in vivo. J Pharmacol Exp Ther 298: 812-819.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 812-819
    • Dautzenberg, F.M.1    Wichmann, J.2    Higelin, J.3    Py-Lang, G.4    Kratzeisen, C.5    Malherbe, P.6
  • 21
    • 0343150924 scopus 로고    scopus 로고
    • Orphanin FQ: Receptor binding and analog structure activity relationships in rat brain
    • Dooley CT, Houghten RA (1996). Orphanin FQ: receptor binding and analog structure activity relationships in rat brain. Life Sci 59: PL23-PL29.
    • (1996) Life Sci , vol.59
    • Dooley, C.T.1    Houghten, R.A.2
  • 24
    • 0038730667 scopus 로고    scopus 로고
    • Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: Pharmacological and genetic evidences from the mouse forced swimming test
    • Gavioli EC, Marzola G, Guerrini R, Bertorelli R, Zucchini S, De Lima TC et al. (2003). Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test. Eur J Neurosci 17: 1987-1990.
    • (2003) Eur J Neurosci , vol.17 , pp. 1987-1990
    • Gavioli, E.C.1    Marzola, G.2    Guerrini, R.3    Bertorelli, R.4    Zucchini, S.5    De Lima, T.C.6
  • 27
    • 0031006367 scopus 로고    scopus 로고
    • Address and message sequences for the nociceptin receptor: A structure-activity study of nociceptin-(1-13)-peptide amide
    • Guerrini R, Calo G, Rizzi A, Bianchi C, Lazarus LH, Salvadori S et al. (1997). Address and message sequences for the nociceptin receptor: a structure-activity study of nociceptin-(1-13)-peptide amide. J Med Chem 40: 1789-1793.
    • (1997) J Med Chem , vol.40 , pp. 1789-1793
    • Guerrini, R.1    Calo, G.2    Rizzi, A.3    Bianchi, C.4    Lazarus, L.H.5    Salvadori, S.6
  • 29
    • 0035028389 scopus 로고    scopus 로고
    • Comparison of pharmacological activities of buprenorphine and norbuprenorphine: Norbuprenorphine is a potent opioid agonist
    • Huang P, Kehner GB, Cowan A, Liu-Chen LY (2001). Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist. J Pharmacol Exp Ther 297: 688-695.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 688-695
    • Huang, P.1    Kehner, G.B.2    Cowan, A.3    Liu-Chen, L.Y.4
  • 30
    • 15644375193 scopus 로고    scopus 로고
    • 3-Alkyl ethers of clocinnamox: Delayed long-term muantagonists with variable mu efficacy
    • Husbands SM, Sadd J, Broadbear JH, Woods JH, Martin J, Traynor JR et al. (1998). 3-Alkyl ethers of clocinnamox: delayed long-term muantagonists with variable mu efficacy. J Med Chem 41: 3493-3498.
    • (1998) J Med Chem , vol.41 , pp. 3493-3498
    • Husbands, S.M.1    Sadd, J.2    Broadbear, J.H.3    Woods, J.H.4    Martin, J.5    Traynor, J.R.6
  • 31
    • 0037674014 scopus 로고    scopus 로고
    • Opioid ligands having delayed longterm antagonist activity: Potential pharmacotherapies for opioid abuse
    • Husbands SM, Lewis JW (2003). Opioid ligands having delayed longterm antagonist activity: potential pharmacotherapies for opioid abuse. Mini Rev Med Chem 3: 137-144.
    • (2003) Mini Rev Med Chem , vol.3 , pp. 137-144
    • Husbands, S.M.1    Lewis, J.W.2
  • 33
    • 0033576679 scopus 로고    scopus 로고
    • Kawamoto H, Ozaki S, Itoh Y, Miyaji M, Arai S, Nakashima H et al. (1999). Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397). J Med Chem 42: 5061-5063.
    • Kawamoto H, Ozaki S, Itoh Y, Miyaji M, Arai S, Nakashima H et al. (1999). Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397). J Med Chem 42: 5061-5063.
  • 34
    • 33846461154 scopus 로고    scopus 로고
    • SR 16435 [1-(1-(bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin- 2-one], a novel mixed nociceptin/orphanin FQ/mu-opioid receptor partial agonist: Analgesic and rewarding properties in mice
    • Khroyan TV, Zaveri NT, Polgar WE, Orduna J, Olsen C, Jiang F et al. (2007). SR 16435 [1-(1-(bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin- 2-one], a novel mixed nociceptin/orphanin FQ/mu-opioid receptor partial agonist: analgesic and rewarding properties in mice. J Pharmacol Exp Ther 320: 934-943.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 934-943
    • Khroyan, T.V.1    Zaveri, N.T.2    Polgar, W.E.3    Orduna, J.4    Olsen, C.5    Jiang, F.6
  • 35
    • 33947262606 scopus 로고    scopus 로고
    • The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking
    • Kuzmin A, Kreek MJ, Bakalkin G, Liljequist S (2007). The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking. Neuropsychopharmacology 32: 902-910.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 902-910
    • Kuzmin, A.1    Kreek, M.J.2    Bakalkin, G.3    Liljequist, S.4
  • 36
    • 33644938251 scopus 로고    scopus 로고
    • Comparison of the in vitro efficacy of mu, delta, kappa and ORL1 receptor agonists and non-selective opioid agonists in dog brain membranes
    • Lester PA, Traynor JR (2006). Comparison of the in vitro efficacy of mu, delta, kappa and ORL1 receptor agonists and non-selective opioid agonists in dog brain membranes. Brain Res 1073-1074: 290-296.
    • (2006) Brain Res , vol.1073-1074 , pp. 290-296
    • Lester, P.A.1    Traynor, J.R.2
  • 37
    • 0345687444 scopus 로고    scopus 로고
    • Buprenorphine-induced antinociception is mediated by mu-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors
    • Lutfy K, Eitan S, Bryant CD, Yang YC, Saliminejad N, Walwyn W et al. (2003). Buprenorphine-induced antinociception is mediated by mu-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors. J Neurosci 23: 10331-10337.
    • (2003) J Neurosci , vol.23 , pp. 10331-10337
    • Lutfy, K.1    Eitan, S.2    Bryant, C.D.3    Yang, Y.C.4    Saliminejad, N.5    Walwyn, W.6
  • 38
    • 0034774632 scopus 로고    scopus 로고
    • Orphanin FQ/nociceptin attenuates the development of morphine tolerance in rats
    • Lutfy K, Hossain SM, Khaliq I, Maidment NT (2001). Orphanin FQ/nociceptin attenuates the development of morphine tolerance in rats. Br J Pharmacol 134: 529-534.
    • (2001) Br J Pharmacol , vol.134 , pp. 529-534
    • Lutfy, K.1    Hossain, S.M.2    Khaliq, I.3    Maidment, N.T.4
  • 39
    • 0035666475 scopus 로고    scopus 로고
    • Morphine tolerance and dependence in the nociceptin receptor knockout mice
    • Mamiya T, Noda Y, Ren X, Nagai T, Takeshima H, Ukai M et al. (2001). Morphine tolerance and dependence in the nociceptin receptor knockout mice. J Neural Transm 108: 1349-1361.
    • (2001) J Neural Transm , vol.108 , pp. 1349-1361
    • Mamiya, T.1    Noda, Y.2    Ren, X.3    Nagai, T.4    Takeshima, H.5    Ukai, M.6
  • 40
    • 0029166509 scopus 로고
    • Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
    • Meunier JC, Mollereau C, Toll L, Suaudeau C, Moisand C, Alvinerie P et al. (1995). Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377: 532-535.
    • (1995) Nature , vol.377 , pp. 532-535
    • Meunier, J.C.1    Mollereau, C.2    Toll, L.3    Suaudeau, C.4    Moisand, C.5    Alvinerie, P.6
  • 41
    • 0030598929 scopus 로고    scopus 로고
    • Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ
    • Mogil JS, Grisel JE, Zhangs G, Belknap JK, Grandy DK (1996). Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ. Neurosci Lett 214: 131-134.
    • (1996) Neurosci Lett , vol.214 , pp. 131-134
    • Mogil, J.S.1    Grisel, J.E.2    Zhangs, G.3    Belknap, J.K.4    Grandy, D.K.5
  • 42
    • 0028226886 scopus 로고
    • ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization
    • Mollereau C, Parmentier M, Mailleux P, Butour JL, Moisand C, Chalon P et al. (1994). ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett 341: 33-38.
    • (1994) FEBS Lett , vol.341 , pp. 33-38
    • Mollereau, C.1    Parmentier, M.2    Mailleux, P.3    Butour, J.L.4    Moisand, C.5    Chalon, P.6
  • 43
    • 0033821652 scopus 로고    scopus 로고
    • Cellular neurophysiological actions of nociceptin/orphanin FQ
    • Moran TD, Abdulla FA, Smith PA (2000). Cellular neurophysiological actions of nociceptin/orphanin FQ. Peptides 21: 969-976.
    • (2000) Peptides , vol.21 , pp. 969-976
    • Moran, T.D.1    Abdulla, F.A.2    Smith, P.A.3
  • 44
    • 0033583931 scopus 로고    scopus 로고
    • Orphanin FQ/nociceptin blocks acquisition of morphine place preference
    • Murphy NP, Lee Y, Maidment NT (1999). Orphanin FQ/nociceptin blocks acquisition of morphine place preference. Brain Res 832: 168-170.
    • (1999) Brain Res , vol.832 , pp. 168-170
    • Murphy, N.P.1    Lee, Y.2    Maidment, N.T.3
  • 45
    • 0344631766 scopus 로고    scopus 로고
    • Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: Comparison of ORL1 receptor mRNA expression with (125)I-[(14)Tyr]-orphanin FQ binding
    • Neal Jr CR, Mansour A, Reinscheid R, Nothacker HP, Civelli O, Akil H et al. (1999). Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: comparison of ORL1 receptor mRNA expression with (125)I-[(14)Tyr]-orphanin FQ binding. J Comp Neurol 412: 563-605.
    • (1999) J Comp Neurol , vol.412 , pp. 563-605
    • Neal Jr, C.R.1    Mansour, A.2    Reinscheid, R.3    Nothacker, H.P.4    Civelli, O.5    Akil, H.6
  • 46
    • 0030983770 scopus 로고    scopus 로고
    • Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphanin FQ receptor
    • Nishi M, Houtani T, Noda Y, Mamiya T, Sato K, Doi T et al. (1997). Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphanin FQ receptor. EMBO J 16: 1858-1864.
    • (1997) EMBO J , vol.16 , pp. 1858-1864
    • Nishi, M.1    Houtani, T.2    Noda, Y.3    Mamiya, T.4    Sato, K.5    Doi, T.6
  • 47
    • 0034683206 scopus 로고    scopus 로고
    • In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist
    • Ozaki S, Kawamoto H, Itoh Y, Miyaji M, Azuma T, Ichikawa D et al. (2000). In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist. Eur J Pharmacol 402: 45-53.
    • (2000) Eur J Pharmacol , vol.402 , pp. 45-53
    • Ozaki, S.1    Kawamoto, H.2    Itoh, Y.3    Miyaji, M.4    Azuma, T.5    Ichikawa, D.6
  • 48
    • 0342726574 scopus 로고    scopus 로고
    • Structure-activity relationship studies on the novel neuropeptide orphanin FQ
    • Reinscheid RK, Ardati A, Monsma Jr FJ, Civelli O (1996). Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J Biol Chem 271: 14163-14168.
    • (1996) J Biol Chem , vol.271 , pp. 14163-14168
    • Reinscheid, R.K.1    Ardati, A.2    Monsma Jr, F.J.3    Civelli, O.4
  • 51
    • 0036139497 scopus 로고    scopus 로고
    • Arg(14),Lys(15)]nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor: In vitro and in vivo studies
    • Rizzi D, Rizzi A, Bigoni R, Camarda V, Marzola G, Guerrini R et al. (2002). Arg(14),Lys(15)]nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor: in vitro and in vivo studies. J Pharmacol Exp Ther 300: 57-63.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 57-63
    • Rizzi, D.1    Rizzi, A.2    Bigoni, R.3    Camarda, V.4    Marzola, G.5    Guerrini, R.6
  • 52
    • 0342749308 scopus 로고    scopus 로고
    • High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor
    • Rover S, Adam G, Cesura AM, Galley G, Jenck F, Monsma Jr FJ et al. (2000). High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor. J Med Chem 43: 1329-1338.
    • (2000) J Med Chem , vol.43 , pp. 1329-1338
    • Rover, S.1    Adam, G.2    Cesura, A.M.3    Galley, G.4    Jenck, F.5    Monsma Jr, F.J.6
  • 53
    • 23844554269 scopus 로고    scopus 로고
    • Shoblock JR, Wichmann J, Maidment NT (2005). The effect of a systemically active ORL-1 agonist, Ro 64-6198, on the acquisition, expression, extinction, and reinstatement of morphine conditioned place preference. Neuropharmacology 49: 439-446.
    • Shoblock JR, Wichmann J, Maidment NT (2005). The effect of a systemically active ORL-1 agonist, Ro 64-6198, on the acquisition, expression, extinction, and reinstatement of morphine conditioned place preference. Neuropharmacology 49: 439-446.
  • 54
    • 0032956076 scopus 로고    scopus 로고
    • Antinociceptive effects of opioids following acute and chronic administration of butorphanol: Influence of stimulus intensity and relative efficacy at the mu receptor
    • Smith MA, Barrett AC, Picker MJ (1999). Antinociceptive effects of opioids following acute and chronic administration of butorphanol: influence of stimulus intensity and relative efficacy at the mu receptor. Psychopharmacology (Berl) 143: 261-269.
    • (1999) Psychopharmacology (Berl) , vol.143 , pp. 261-269
    • Smith, M.A.1    Barrett, A.C.2    Picker, M.J.3
  • 55
    • 0242499509 scopus 로고    scopus 로고
    • Effect of JTC-801 (nociceptin antagonist) on neuropathic pain in a rat model
    • Suyama H, Kawamoto M, Gaus S, Yuge O (2003). Effect of JTC-801 (nociceptin antagonist) on neuropathic pain in a rat model. Neurosci Lett 351: 133-136.
    • (2003) Neurosci Lett , vol.351 , pp. 133-136
    • Suyama, H.1    Kawamoto, M.2    Gaus, S.3    Yuge, O.4
  • 56
    • 8044238345 scopus 로고    scopus 로고
    • Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: Antagonism in brain and potentiation in spinal cord of the rat
    • Tian JH, Xu W, Fang Y, Mogil JS, Grisel JE, Grandy DK et al. (1997). Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat. Br J Pharmacol 120: 676-680.
    • (1997) Br J Pharmacol , vol.120 , pp. 676-680
    • Tian, J.H.1    Xu, W.2    Fang, Y.3    Mogil, J.S.4    Grisel, J.E.5    Grandy, D.K.6
  • 57
    • 0032012257 scopus 로고    scopus 로고
    • Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications
    • Toll L, Berzetei-Gurske IP, Polgar WE, Brandt SR, Adapa ID, Rodriguez L et al. (1998). Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA Res Monogr 178: 440-466.
    • (1998) NIDA Res Monogr , vol.178 , pp. 440-466
    • Toll, L.1    Berzetei-Gurske, I.P.2    Polgar, W.E.3    Brandt, S.R.4    Adapa, I.D.5    Rodriguez, L.6
  • 58
    • 0028986870 scopus 로고
    • 35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells
    • 35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells. Mol Pharmacol 47: 848-854.
    • (1995) Mol Pharmacol , vol.47 , pp. 848-854
    • Traynor, J.R.1    Nahorski, S.R.2
  • 59
    • 0034667560 scopus 로고    scopus 로고
    • Enhanced spinal nociceptin receptor expression develops morphine tolerance and dependence
    • Ueda H, Inoue M, Takeshima H, Iwasawa Y (2000). Enhanced spinal nociceptin receptor expression develops morphine tolerance and dependence. J Neurosci 20: 7640-7647.
    • (2000) J Neurosci , vol.20 , pp. 7640-7647
    • Ueda, H.1    Inoue, M.2    Takeshima, H.3    Iwasawa, Y.4
  • 61
    • 0345552248 scopus 로고    scopus 로고
    • Agonistic effect of buprenorphine in a nociceptin/OFQ receptor-triggered reporter gene assay
    • Wnendt S, Kruger T, Janocha E, Hildebrandt D, Englberger W (1999). Agonistic effect of buprenorphine in a nociceptin/OFQ receptor-triggered reporter gene assay. Mol Pharmacol 56: 334-338.
    • (1999) Mol Pharmacol , vol.56 , pp. 334-338
    • Wnendt, S.1    Kruger, T.2    Janocha, E.3    Hildebrandt, D.4    Englberger, W.5
  • 62
    • 0028991723 scopus 로고
    • Methoclocinnamox: A mu partial agonist with pharmacotherapeutic potential for heroin abuse
    • Woods JH, Lewis JW, Winger G, Butelman E, Broadbear J, Zernig G (1995). Methoclocinnamox: a mu partial agonist with pharmacotherapeutic potential for heroin abuse. NIDA Res Monogr 147: 195-219.
    • (1995) NIDA Res Monogr , vol.147 , pp. 195-219
    • Woods, J.H.1    Lewis, J.W.2    Winger, G.3    Butelman, E.4    Broadbear, J.5    Zernig, G.6
  • 63
    • 0029806549 scopus 로고    scopus 로고
    • Nociceptin or antinociceptin: Potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat
    • Xu XJ, Hao JX, Wiesenfeld-Hallin Z (1996). Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat. NeuroReport 7: 2092-2094.
    • (1996) NeuroReport , vol.7 , pp. 2092-2094
    • Xu, X.J.1    Hao, J.X.2    Wiesenfeld-Hallin, Z.3
  • 64
    • 0036177296 scopus 로고    scopus 로고
    • Pharmacological profiles of a novel opioid receptor-like1 (ORL(1)) receptor antagonist, JTC-801
    • Yamada H, Nakamoto H, Suzuki Y, Ito T, Aisaka K (2002). Pharmacological profiles of a novel opioid receptor-like1 (ORL(1)) receptor antagonist, JTC-801. Br J Pharmacol 135: 323-332.
    • (2002) Br J Pharmacol , vol.135 , pp. 323-332
    • Yamada, H.1    Nakamoto, H.2    Suzuki, Y.3    Ito, T.4    Aisaka, K.5
  • 65
    • 1642498186 scopus 로고    scopus 로고
    • Modification of nociception and morphine tolerance by the selective opiate receptor-like orphan receptor antagonist (-)-cis-1- methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8, 9-tetrahydro-5H-benzocyclohepten-5-ol (SB-612111)
    • Zaratin PF, Petrone G, Sbacchi M, Garnier M, Fossati C, Petrillo P et al. (2004). Modification of nociception and morphine tolerance by the selective opiate receptor-like orphan receptor antagonist (-)-cis-1- methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8, 9-tetrahydro-5H-benzocyclohepten-5-ol (SB-612111). J Pharmacol Exp Ther 308: 454-461.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 454-461
    • Zaratin, P.F.1    Petrone, G.2    Sbacchi, M.3    Garnier, M.4    Fossati, C.5    Petrillo, P.6
  • 66
    • 0037498440 scopus 로고    scopus 로고
    • Peptide and nonpeptide ligands for the nociceptin/orphanin FQ receptor ORL1: Research tools and potential therapeutic agents
    • Zaveri N (2003). Peptide and nonpeptide ligands for the nociceptin/orphanin FQ receptor ORL1: research tools and potential therapeutic agents. Life Sci 73: 663-678.
    • (2003) Life Sci , vol.73 , pp. 663-678
    • Zaveri, N.1
  • 67
    • 30544437362 scopus 로고    scopus 로고
    • Small-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): Ligand-based analysis of structural factors influencing intrinsic activity at NOP
    • Zaveri N, Jiang F, Olsen C, Polgar W, Toll L (2005). Small-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): ligand-based analysis of structural factors influencing intrinsic activity at NOP. AAPS J 7: E345-E352.
    • (2005) AAPS J , vol.7
    • Zaveri, N.1    Jiang, F.2    Olsen, C.3    Polgar, W.4    Toll, L.5
  • 68
    • 0035964719 scopus 로고    scopus 로고
    • Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors
    • Zaveri N, Polgar WE, Olsen CM, Kelson AB, Grundt P, Lewis JW et al. (2001). Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors. Eur J Pharmacol 428: 29-36.
    • (2001) Eur J Pharmacol , vol.428 , pp. 29-36
    • Zaveri, N.1    Polgar, W.E.2    Olsen, C.M.3    Kelson, A.B.4    Grundt, P.5    Lewis, J.W.6
  • 69
    • 2542609191 scopus 로고    scopus 로고
    • A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor
    • Zaveri NT, Jiang F, Olsen CM, Deschamps JR, Parrish D, Polgar W et al. (2004). A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor. J Med Chem 47: 2973-2976.
    • (2004) J Med Chem , vol.47 , pp. 2973-2976
    • Zaveri, N.T.1    Jiang, F.2    Olsen, C.M.3    Deschamps, J.R.4    Parrish, D.5    Polgar, W.6


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