Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: Antagonism in brain and potentiation in spinal cord of the rat

British Journal of Pharmacology

Volumn 120, Issue 4, 1997, Pages 676-680

  Tian, Jin Hua ^a   Xu, Wei ^a   Fang, Yuan ^b,c   Mogil, Jeffrey S ^b   Grisel, Judith E ^b   Grandy, David K ^b   Han, Ji Sheng ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Analgesia; Anti opioid; Morphine withdrawal; ORL1 LC132; Orphanin FQ nociceptin

Indexed keywords

LIGAND; MORPHINE; NOCICEPTIN; OPIATE RECEPTOR;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CONTROLLED STUDY; DOSE RESPONSE; DRUG DEPENDENCE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; LATENT PERIOD; LOCUS CERULEUS; MALE; MODULATION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD; WITHDRAWAL SYNDROME;

ANALGESIA; ANALGESICS, OPIOID; ANIMALS; BRAIN; DRUG INTERACTIONS; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; MALE; MORPHINE; OPIOID PEPTIDES; PAIN MEASUREMENT; RATS; RATS, WISTAR; RECEPTORS, OPIOID; SPINAL CORD;

EID: 8044238345     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0700942     Document Type: Article

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