Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: Pharmacological and genetic evidences from the mouse forced swimming test

European Journal of Neuroscience

Volumn 17, Issue 9, 2003, Pages 1987-1990

  Gavioli, E C ^a   Marzola, G ^a   Guerrini, R ^a   Bertorelli, R ^b   Zucchini, S ^a   De Lima, T C M ^c   Rae, G A ^c   Salvadori, S ^a   Regoli, D ^a   Calo, Girolamo ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b Schering Plough Research Institute   (Italy)

^c FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Animal depression model; Depression; i.c.v. injection; Knockout mice; UFP 101

Indexed keywords

ANTIDEPRESSANT AGENT; NOCICEPTIN; NOCICEPTIN RECEPTOR; NOCICEPTIN RECEPTOR ANTAGONIST; UFP 101; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DOSE RESPONSE; DRUG EFFECT; FORCED SWIMMING TEST; KNOCKOUT MOUSE; MALE; MENTAL DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIDEPRESSIVE AGENTS; DEPRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMOBILIZATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, OPIOID; SIGNAL TRANSDUCTION; SWIMMING;

EID: 0038730667     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02603.x     Document Type: Article

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