메뉴 건너뛰기




Volumn 48, Issue 11, 2007, Pages 5199-5206

Constitutive and AP20187-induced ret activation in photoreceptors does not protect from light-induced damage

Author keywords

[No Author keywords available]

Indexed keywords

AP 20187; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NEUROPROTECTIVE AGENT; PARVOVIRUS VECTOR; PROTEIN RET; RHODOPSIN; UNCLASSIFIED DRUG; AP20187; DRUG DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; RET PROTEIN, MOUSE; TACROLIMUS;

EID: 38449103915     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.07-0140     Document Type: Article
Times cited : (15)

References (59)
  • 2
    • 0026462896 scopus 로고
    • Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light
    • LaVail MM, Unoki K, Yasumura D, Matthes MT, Yancopoulos GD, Steinberg RH. Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc Natl Acad Sci USA. 1992;89:11249-11253.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11249-11253
    • LaVail, M.M.1    Unoki, K.2    Yasumura, D.3    Matthes, M.T.4    Yancopoulos, G.D.5    Steinberg, R.H.6
  • 3
    • 0031937530 scopus 로고    scopus 로고
    • Protection of mouse photoreceptors by survival factors in retinal degenerations
    • LaVail MM, Yasumura D, Matthes MT, et al. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci. 1998;39:592-602.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 592-602
    • LaVail, M.M.1    Yasumura, D.2    Matthes, M.T.3
  • 4
    • 0033774933 scopus 로고    scopus 로고
    • Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2
    • Lau D, McGee LH, Zhou S, et al. Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2. Invest Ophthalmol Vis Sci. 2000;41:3622-3633.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3622-3633
    • Lau, D.1    McGee, L.H.2    Zhou, S.3
  • 5
    • 0034980919 scopus 로고    scopus 로고
    • Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18
    • Green ES, Rendahl KG, Zhou S, et al. Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18. Mol Ther. 2001;3:507-515.
    • (2001) Mol Ther , vol.3 , pp. 507-515
    • Green, E.S.1    Rendahl, K.G.2    Zhou, S.3
  • 6
    • 0037214277 scopus 로고    scopus 로고
    • Retinal neuroprotection by growth factors: A mechanistic perspective
    • Chaum E. Retinal neuroprotection by growth factors: a mechanistic perspective. J Cell Biochem. 2003;88:57-75.
    • (2003) J Cell Biochem , vol.88 , pp. 57-75
    • Chaum, E.1
  • 7
    • 0037230914 scopus 로고    scopus 로고
    • Viral-mediated FGF-2 treatment of the constant light damage model of photoreceptor degeneration
    • Lau D, Flannery J. Viral-mediated FGF-2 treatment of the constant light damage model of photoreceptor degeneration. Doc Ophthalmol. 2003;106:89-98.
    • (2003) Doc Ophthalmol , vol.106 , pp. 89-98
    • Lau, D.1    Flannery, J.2
  • 8
    • 0032829894 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse
    • Frasson M, Picaud S, Leveillard T, et al. Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse. Invest Ophthalmol Vis Sci. 1999;40:2724-2734.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2724-2734
    • Frasson, M.1    Picaud, S.2    Leveillard, T.3
  • 9
    • 28344448740 scopus 로고    scopus 로고
    • Intravitreous injection of PLGA microspheres encapsulating GDNF promotes the survival of photoreceptors in the rd1/rd1 mouse
    • Andrieu-Soler C, Aubert-Pouessel A, Doat M, et al. Intravitreous injection of PLGA microspheres encapsulating GDNF promotes the survival of photoreceptors in the rd1/rd1 mouse. Mol Vis. 2005;11:1002-1011.
    • (2005) Mol Vis , vol.11 , pp. 1002-1011
    • Andrieu-Soler, C.1    Aubert-Pouessel, A.2    Doat, M.3
  • 10
    • 33749236815 scopus 로고    scopus 로고
    • In contrast to AAV-mediated cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration
    • Buch PK, MacLaren RE, Duran Y, et al. In contrast to AAV-mediated cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration. Mol Ther. 2006;14:700-709.
    • (2006) Mol Ther , vol.14 , pp. 700-709
    • Buch, P.K.1    MacLaren, R.E.2    Duran, Y.3
  • 11
    • 0035664438 scopus 로고    scopus 로고
    • Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa
    • McGee Sanftner LH, Abel H, Hauswirth WW, Flannery JG. Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa. Mol Ther. 2001;4:622-629.
    • (2001) Mol Ther , vol.4 , pp. 622-629
    • McGee Sanftner, L.H.1    Abel, H.2    Hauswirth, W.W.3    Flannery, J.G.4
  • 12
    • 0033564046 scopus 로고    scopus 로고
    • Activation of caspase-3 in the retina of transgenic rats with the rhodopsin mutation s334ter during photoreceptor degeneration
    • Liu C, Li Y, Peng M, Laties AM, Wen R. Activation of caspase-3 in the retina of transgenic rats with the rhodopsin mutation s334ter during photoreceptor degeneration. J Neurosci. 1999;19:4778-4785.
    • (1999) J Neurosci , vol.19 , pp. 4778-4785
    • Liu, C.1    Li, Y.2    Peng, M.3    Laties, A.M.4    Wen, R.5
  • 13
    • 0032990606 scopus 로고    scopus 로고
    • Caspaselike proteases activated in apoptotic photoreceptors of Royal College of Surgeons rats
    • Katai N, Kikuchi T, Shibuki H, et al. Caspaselike proteases activated in apoptotic photoreceptors of Royal College of Surgeons rats. Invest Ophthalmol Vis Sci. 1999;40:1802-1807.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 1802-1807
    • Katai, N.1    Kikuchi, T.2    Shibuki, H.3
  • 14
    • 0037707639 scopus 로고    scopus 로고
    • Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration
    • Doonan F, Donovan M, Cotter TG. Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration. J Neurosci. 2003;23:5723-5731.
    • (2003) J Neurosci , vol.23 , pp. 5723-5731
    • Doonan, F.1    Donovan, M.2    Cotter, T.G.3
  • 15
    • 33645713234 scopus 로고    scopus 로고
    • Expression of c-Jun and Bcl-2 family proteins in apoptotic photoreceptors of RCS rats
    • Katai N, Yanagidaira T, Senda N, Murata T, Yoshimura N. Expression of c-Jun and Bcl-2 family proteins in apoptotic photoreceptors of RCS rats. Jpn J Ophthalmol. 2006;50:121-127.
    • (2006) Jpn J Ophthalmol , vol.50 , pp. 121-127
    • Katai, N.1    Yanagidaira, T.2    Senda, N.3    Murata, T.4    Yoshimura, N.5
  • 16
    • 33751239138 scopus 로고    scopus 로고
    • Sanges D, Comitato A, Tammaro R, Marigo V. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci USA. 2006;103-17366-17371
    • Sanges D, Comitato A, Tammaro R, Marigo V. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci USA. 2006;103-17366-17371
  • 17
    • 33747415096 scopus 로고    scopus 로고
    • Cross-talk between two apoptotic pathways activated by endoplasmic reticulum stress: Differential contribution of caspase-12 and AIF
    • Sanges D, Marigo V. Cross-talk between two apoptotic pathways activated by endoplasmic reticulum stress: differential contribution of caspase-12 and AIF. Apoptosis. 2006;11:1629-1641.
    • (2006) Apoptosis , vol.11 , pp. 1629-1641
    • Sanges, D.1    Marigo, V.2
  • 19
    • 15844365303 scopus 로고    scopus 로고
    • GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF
    • Jing S, Wen D, Yu Y, et al. GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell. 1996;85:1113-1124.
    • (1996) Cell , vol.85 , pp. 1113-1124
    • Jing, S.1    Wen, D.2    Yu, Y.3
  • 20
    • 0038488948 scopus 로고    scopus 로고
    • The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands
    • Paratcha G, Ledda F, Ibanez CF. The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands. Cell. 2003;113:867-879.
    • (2003) Cell , vol.113 , pp. 867-879
    • Paratcha, G.1    Ledda, F.2    Ibanez, C.F.3
  • 21
    • 0142106351 scopus 로고    scopus 로고
    • Novel functions and signalling pathways for GDNF
    • Sariola H, Saarma M. Novel functions and signalling pathways for GDNF. J Cell Sci 2003;116:3855-3862.
    • (2003) J Cell Sci , vol.116 , pp. 3855-3862
    • Sariola, H.1    Saarma, M.2
  • 22
    • 0025166103 scopus 로고
    • Expression of the cell surface antigens RET-PE2 and N-CAM by rat retinal pigment epithelial cells during development and in tissue culture
    • Neill JM, Barnstable CJ. Expression of the cell surface antigens RET-PE2 and N-CAM by rat retinal pigment epithelial cells during development and in tissue culture. Exp Eye Res. 1990;51:573-583.
    • (1990) Exp Eye Res , vol.51 , pp. 573-583
    • Neill, J.M.1    Barnstable, C.J.2
  • 23
    • 0033052246 scopus 로고    scopus 로고
    • Expression patterns of neurturin and its receptor components in developing and degenerative mouse retina
    • Jomary C, Thomas M, Grist J, Milbrandt J, Neal MJ, Jones SE. Expression patterns of neurturin and its receptor components in developing and degenerative mouse retina. Invest Ophthalmol Vis Sci. 1999;40:568-574.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 568-574
    • Jomary, C.1    Thomas, M.2    Grist, J.3    Milbrandt, J.4    Neal, M.J.5    Jones, S.E.6
  • 24
    • 0037139305 scopus 로고    scopus 로고
    • Neurturin enhances the survival of axotomized retinal ganglion cells in vivo: Combined effects with glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor
    • Koeberle PD, Ball AK. Neurturin enhances the survival of axotomized retinal ganglion cells in vivo: combined effects with glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor. Neuroscience. 2002;110:555-567.
    • (2002) Neuroscience , vol.110 , pp. 555-567
    • Koeberle, P.D.1    Ball, A.K.2
  • 26
    • 8044254622 scopus 로고    scopus 로고
    • Identification of Shc docking site on Ret tyrosine kinase
    • Arighi E, Alberti L, Torriti F, et al. Identification of Shc docking site on Ret tyrosine kinase. Oncogene. 1997;14:773-782.
    • (1997) Oncogene , vol.14 , pp. 773-782
    • Arighi, E.1    Alberti, L.2    Torriti, F.3
  • 27
    • 0035474473 scopus 로고    scopus 로고
    • Signaling via Shc family adapter proteins
    • Ravichandran KS. Signaling via Shc family adapter proteins. Oncogene. 2001;20:6322-6330.
    • (2001) Oncogene , vol.20 , pp. 6322-6330
    • Ravichandran, K.S.1
  • 28
    • 0023479273 scopus 로고
    • Light-induced retinal degeneration in albino mice and rats: Strain and species differences
    • LaVail MM, Gorrin GM, Repaci MA, Yasumura D. Light-induced retinal degeneration in albino mice and rats: strain and species differences. Prog Clin Biol Res. 1987;247:439-454.
    • (1987) Prog Clin Biol Res , vol.247 , pp. 439-454
    • LaVail, M.M.1    Gorrin, G.M.2    Repaci, M.A.3    Yasumura, D.4
  • 30
    • 11144273817 scopus 로고    scopus 로고
    • Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration
    • Wenzel A, Grimm C, Samardzija M, Reme CE. Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration. Prog Retin Eye Res. 2005;24:275-306.
    • (2005) Prog Retin Eye Res , vol.24 , pp. 275-306
    • Wenzel, A.1    Grimm, C.2    Samardzija, M.3    Reme, C.E.4
  • 31
    • 39349092530 scopus 로고    scopus 로고
    • Visual Functional Effects of Constant Blue Light in a Retinal Degenerate Rat Model
    • Published online September 1
    • Thomas BB, Seiler MJ, Aramant RB, et al. Visual Functional Effects of Constant Blue Light in a Retinal Degenerate Rat Model. Photochem Photobiol. Published online September 1, 2006.
    • (2006) Photochem Photobiol
    • Thomas, B.B.1    Seiler, M.J.2    Aramant, R.B.3
  • 32
    • 0030808480 scopus 로고    scopus 로고
    • Expression of a mutant opsin gene increases the susceptibility of the retina to light damage
    • Wang M, Lam TT, Tso MO, Naash MI. Expression of a mutant opsin gene increases the susceptibility of the retina to light damage. Vis Neurosci. 1997;14:55-62.
    • (1997) Vis Neurosci , vol.14 , pp. 55-62
    • Wang, M.1    Lam, T.T.2    Tso, M.O.3    Naash, M.I.4
  • 33
    • 0142195831 scopus 로고    scopus 로고
    • Potential role of glial cell line-derived neurotrophic factor receptors in Muller glial cells during light-induced retinal degeneration
    • Harada C, Harada T, Quah HM, et al. Potential role of glial cell line-derived neurotrophic factor receptors in Muller glial cells during light-induced retinal degeneration. Neuroscience. 2003;122:229-235.
    • (2003) Neuroscience , vol.122 , pp. 229-235
    • Harada, C.1    Harada, T.2    Quah, H.M.3
  • 34
    • 2142822260 scopus 로고    scopus 로고
    • Expression of neurturin, glial cell line-derived neurotrophic factor, and their receptor components in light-induced retinal degeneration
    • Jomary C, Darrow RM, Wong P, Organisciak DT, Jones SE. Expression of neurturin, glial cell line-derived neurotrophic factor, and their receptor components in light-induced retinal degeneration. Invest Ophthalmol Vis Sci. 2004;45:1240-1246.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1240-1246
    • Jomary, C.1    Darrow, R.M.2    Wong, P.3    Organisciak, D.T.4    Jones, S.E.5
  • 35
    • 0032098247 scopus 로고    scopus 로고
    • Rod outer segment maintenance is enhanced in the presence of bFGF, CNTF and GDNF
    • Carwile ME, Culbert RB, Sturdivant RL, Kraft TW. Rod outer segment maintenance is enhanced in the presence of bFGF, CNTF and GDNF. Exp Eye Res. 1998;66:791-805.
    • (1998) Exp Eye Res , vol.66 , pp. 791-805
    • Carwile, M.E.1    Culbert, R.B.2    Sturdivant, R.L.3    Kraft, T.W.4
  • 36
    • 0036850873 scopus 로고    scopus 로고
    • Microglia-Muller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration
    • Harada T, Harada C, Kohsaka S, et al. Microglia-Muller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. J Neurosci. 2002;22:9228-9236.
    • (2002) J Neurosci , vol.22 , pp. 9228-9236
    • Harada, T.1    Harada, C.2    Kohsaka, S.3
  • 37
    • 21244468704 scopus 로고    scopus 로고
    • Adeno-associated viral vectors for retinal gene transfer and treatment of retinal diseases
    • Auricchio A, Rolling F. Adeno-associated viral vectors for retinal gene transfer and treatment of retinal diseases. Curr Gene Ther. 2005;5:339-348.
    • (2005) Curr Gene Ther , vol.5 , pp. 339-348
    • Auricchio, A.1    Rolling, F.2
  • 38
    • 0035894739 scopus 로고    scopus 로고
    • Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: The retina as a model
    • Auricchio A, Kobinger G, Anand V, et al. Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model. Hum Mol Genet. 2001;10:3075-3081.
    • (2001) Hum Mol Genet , vol.10 , pp. 3075-3081
    • Auricchio, A.1    Kobinger, G.2    Anand, V.3
  • 39
    • 0036310297 scopus 로고    scopus 로고
    • Virus-mediated transduction of murine retina with adeno-associated virus: Effects of viral capsid and genome size
    • Yang GS, Schmidt M, Yan Z, et al. Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size. J Virol. 2002;76:7651-7660.
    • (2002) J Virol , vol.76 , pp. 7651-7660
    • Yang, G.S.1    Schmidt, M.2    Yan, Z.3
  • 40
    • 10744225428 scopus 로고    scopus 로고
    • Adeno-associated virus type 5: Transduction efficiency and cell-type specificity in the primate retina
    • Lotery AJ, Yang GS, Mullins RF, et al. Adeno-associated virus type 5: transduction efficiency and cell-type specificity in the primate retina. Hum Gene Ther. 2003;14:1663-1671.
    • (2003) Hum Gene Ther , vol.14 , pp. 1663-1671
    • Lotery, A.J.1    Yang, G.S.2    Mullins, R.F.3
  • 42
    • 0030931963 scopus 로고    scopus 로고
    • Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector
    • Miyoshi H, Takahashi M, Gage FH, Verma IM. Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc Natl Acad Sci USA. 1997;94:10319-10323.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10319-10323
    • Miyoshi, H.1    Takahashi, M.2    Gage, F.H.3    Verma, I.M.4
  • 43
    • 12644251038 scopus 로고    scopus 로고
    • A versatile synthetic dimerizer for the regulation of protein-protein interactions
    • Amara JF, Clackson T, Rivera VM, et al. A versatile synthetic dimerizer for the regulation of protein-protein interactions. Proc Natl Acad Sci USA. 1997;94:10618-10623.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10618-10623
    • Amara, J.F.1    Clackson, T.2    Rivera, V.M.3
  • 45
    • 0035989652 scopus 로고    scopus 로고
    • Regulation of endogenous gene expression with a small-molecule dimerizer
    • Pollock R, Giel M, Linher K, Clackson T. Regulation of endogenous gene expression with a small-molecule dimerizer. Nat Biotech. 2002;20:729-733.
    • (2002) Nat Biotech , vol.20 , pp. 729-733
    • Pollock, R.1    Giel, M.2    Linher, K.3    Clackson, T.4
  • 46
    • 0033812431 scopus 로고    scopus 로고
    • In vivo selection using a cell-growth switch
    • Jin L, Zeng H, Chien S, et al. In vivo selection using a cell-growth switch. Nat Genet. 2000;26:64-66.
    • (2000) Nat Genet , vol.26 , pp. 64-66
    • Jin, L.1    Zeng, H.2    Chien, S.3
  • 48
    • 0037105534 scopus 로고    scopus 로고
    • Pharmacologically regulated in vivo selection in a large animal
    • Neff T, Horn PA, Valli VE, et al. Pharmacologically regulated in vivo selection in a large animal. Blood. 2002;100:2026-2031.
    • (2002) Blood , vol.100 , pp. 2026-2031
    • Neff, T.1    Horn, P.A.2    Valli, V.E.3
  • 49
    • 0037071550 scopus 로고    scopus 로고
    • Inducible dimerization of FGFR1: Development of a mouse model to analyze progressive transformation of the mammary gland
    • Welm BE, Freeman KW, Chen M, Contreras A, Spencer DM, Rosen JM. Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland. J Cell Biol. 2002;157:703-714.
    • (2002) J Cell Biol , vol.157 , pp. 703-714
    • Welm, B.E.1    Freeman, K.W.2    Chen, M.3    Contreras, A.4    Spencer, D.M.5    Rosen, J.M.6
  • 50
    • 0036222251 scopus 로고    scopus 로고
    • Dimerizer-induced proliferation of genetically modified hepatocytes
    • Li ZY, Otto K, Richard RE, et al. Dimerizer-induced proliferation of genetically modified hepatocytes. Mol Ther. 2002;5:420-426.
    • (2002) Mol Ther , vol.5 , pp. 420-426
    • Li, Z.Y.1    Otto, K.2    Richard, R.E.3
  • 51
    • 0037243960 scopus 로고    scopus 로고
    • Small-molecule-directed mp1 signaling can complement growth factors to selectively expand genetically modified cord blood cells
    • Richard RE, Blau CA. Small-molecule-directed mp1 signaling can complement growth factors to selectively expand genetically modified cord blood cells. Stem Cells. 2003;21:71-78.
    • (2003) Stem Cells , vol.21 , pp. 71-78
    • Richard, R.E.1    Blau, C.A.2
  • 52
    • 19944403877 scopus 로고    scopus 로고
    • Pharmacologically regulated regeneration of functional human pancreatic islets
    • Kobinger GP, Deng S, Louboutin JP, et al. Pharmacologically regulated regeneration of functional human pancreatic islets. Mol Ther. 2005;11:105-111.
    • (2005) Mol Ther , vol.11 , pp. 105-111
    • Kobinger, G.P.1    Deng, S.2    Louboutin, J.P.3
  • 53
    • 0034766041 scopus 로고    scopus 로고
    • A single-step affinity column for purification of serotype-5 based adeno-associated viral vectors
    • Auricchio A, O'Connor E, Hildinger M, Wilson JM. A single-step affinity column for purification of serotype-5 based adeno-associated viral vectors. Mol Ther. 2001;4:372-374.
    • (2001) Mol Ther , vol.4 , pp. 372-374
    • Auricchio, A.1    O'Connor, E.2    Hildinger, M.3    Wilson, J.M.4
  • 54
    • 0028914683 scopus 로고
    • Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B
    • Santoro M, Carlomagno F, Romano A, et al. Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B. Science. 1995;267:381-383.
    • (1995) Science , vol.267 , pp. 381-383
    • Santoro, M.1    Carlomagno, F.2    Romano, A.3
  • 55
    • 0034633742 scopus 로고    scopus 로고
    • Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo
    • Gao G, Qu G, Burnham MS, et al. Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo. Hum Gene Ther. 2000;11:2079-2091.
    • (2000) Hum Gene Ther , vol.11 , pp. 2079-2091
    • Gao, G.1    Qu, G.2    Burnham, M.S.3
  • 56
    • 0027493872 scopus 로고
    • Efficacy of tribromoethanol anesthesia in mice
    • Papaioannou VE, Fox JG. Efficacy of tribromoethanol anesthesia in mice. Lab Anim Sci. 1993;43:189-192.
    • (1993) Lab Anim Sci , vol.43 , pp. 189-192
    • Papaioannou, V.E.1    Fox, J.G.2
  • 58
    • 0036664935 scopus 로고    scopus 로고
    • Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye
    • Auricchio A, Rivera V, Clackson T, et al. Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye. Mol Ther. 2002;6:238-242
    • (2002) Mol Ther , vol.6 , pp. 238-242
    • Auricchio, A.1    Rivera, V.2    Clackson, T.3
  • 59
    • 0036787618 scopus 로고    scopus 로고
    • Evidence for two apoptotic pathways in light-induced retinal degeneration
    • Hao W, Wenzel A, Obin MS, et al. Evidence for two apoptotic pathways in light-induced retinal degeneration. Nat Genet. 2002;32:254-260.
    • (2002) Nat Genet , vol.32 , pp. 254-260
    • Hao, W.1    Wenzel, A.2    Obin, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.