Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 11, 1999, Pages 2724-2734

  Frasson, Maria ^a   Picaud, Serge ^a   Léveillard, Thierry ^a   Simonutti, Manuel ^a   Mohand Said, Saddek ^a   Dreyfus, Henri ^a   Hicks, David ^a   Sahel, José ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CONTROLLED STUDY; DRUG MECHANISM; ELECTRORETINOGRAPHY; HISTOLOGY; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RETINA DEGENERATION; RETINA ROD; RETINITIS PIGMENTOSA;

ANIMALS; CELL COUNT; CELL LINE; CELL SURVIVAL; ELECTRORETINOGRAPHY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEUROGLIA; NEUROPROTECTIVE AGENTS; OPSIN; RETINAL DEGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RODS (RETINA);

EID: 0032829894     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Dryja TP, McGee TL, Hahn LB, et al. Mutations within the rhodopsin gene in patients with autosomal dominant retinitis pigmentosa. N Engl J Med. 1990;323:1302-1307.
2. McLaughlin ME, Sandberg MA, Berson EL, Dryja TP. Recessive mutations in the gene encoding the β-subunit of rod phosphodiesterase in patients with retinitis pigmentosa. Nat Genet. 1993;4: 130-133.
3. Travis GH, Brennan MB, Danielson PE, et al. Identification of a photoreceptor-specific mRNA encoded by the gene responsible for retinal degeneration slow. Nature. 1989;338:70-73.
4. Bennet J, Tanabe T, Dun D, et al. Photoreceptor cell rescue in degeneration (rd) mice by in vivo gene therapy. Nat Med. 1996; 2:649-654.
5. Steinberg RH. Survival factors in retinal degenerations. Curr Opin Neurobiol. 1994;4:515-524.
6. LaVail MM, Yasumura D, Matthes MT, et al. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci. 1998;39:592-602.
7. Berson EL, Rosner B, Sandberg MA, et al. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. Arch Ophthalmol. 1993;111:761-772.
8. Del Cerro M, Notter MFD, Cerro C, et al. Intraretinal transplantation for rod-cell replacement in light-damaged retinas. J Neural Transplant. 1989;1:1-10.
9. Silverman MS, Hughes SE. Transplantation of photoreceptors to light-damaged rat. Invest Ophthalmol Vis Sci. 1989;30:1684-90.
10. Faktorovich EG, Steinberg RH, Yasumura D, et al. Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor. Nature. 1990;347:83-86.
11. Faktorovich EG, Steinberg RH, Yasumura D, et al. Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat. J Neurosci. 1992;12:3554-3567.
12. Hicks D, Courtois Y. Fibroblast growth factor stimulates photoreceptor differentiation in vitro. J Neurosci. 1992;12:2022-2033.
13. Chang G-Q, Hay Y, Wong F. Apoptosis: final common pathway of photoreceptor death in rd, rds and rhodopsin mutant mice. Neuron. 1993;11:595-605.
14. Carter-Dawson LD, LaVail M, Sidman RL. Differential effect of the rd mutation on rods and cones in the mouse retina. Invest Ophthalmol Visual Sci. 1978;17:489-498.
15. Bowes C, Li T, Dancinger M, Baxter LC, Farber DB. Retinal degeneration in rd mouse is caused by a defect in the β-subunit of rod cGMP-phosphodiesterase. Nature. 1990;347:677-680.
16. Dryja TP, Finn JT, Peng YW, McGee Tl, Berson EL, Yau KW. Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa. Proc Natl Acad Sci USA. 1995;92:10177-10181.
17. Lin L-FH, Doherty DH, Lile JD, Bektesh S, Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science. 1993;260:1130-1132.
18. Kaddis FG, Zawada WM, Schaack J, Freed CR. Conditioned medium from aged monkey fibroblasts stably expressing GDNF and BDNF improves survival of embryonic dopamine neurons in vitro. Cell Tissue Res. 1996;286:241-247.
19. Gash DM, Zhang Z, Ovadia A, et al. Functional recovery in parkinsonian monkeys treated with GDNF. Nature. 1996;380:252-255.
20. Choi-Lundberg DL, Lin Q, Chang Y-N, et al. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science. 1997;275:838-841.
21. Oppenheim RW, Houenou LJ, Johnson JE, et al. Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF. Nature. 1995;373:344-346.
22. Nosrat CA, Tomac A, Lindqvist E, et al. Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system. Cell Tissue Res. 1996;286:191-207.
23. Jing S, Wen D, Yu Y, et al. GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNF. Cell. 1996;85:1113-1124.
24. Carwile ME, Culbert RB, Sturdivant RL, Kraft TW. Rod outer segment is enhanced in the presence of bFGF, CNTF and GDNF. Exp Eye Res. 1998;66:791-805.
25. Grant GB, Werblin FS. Low-cost data acquisition and analysis programs for electrophysiology. J Neurosci Methods. 1994;55:89-98.
26. Hicks D, Molday RS. Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin. Exp Eye Res. 1986;42:55-71.
27. Gundersen HJG, Bendtsen TF, Korbo L, et al. Some new, simple and efficient stereological methods and their use en pathological research and diagnosis. APMIS. 1988;96:379-394.
28. Gundersen HJG, Bagger P, Bendtsen TF, et al. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS. 1988;96:857-881.
29. Chelly J, Kaplan JC, Maire P, Gautron S, Kahn A. Transcription of the dystrophin gene in human muscle and non-muscle tissue. Nature. 1988;333:858-860.
30. Anderson KJ, Dam D, Lee S, Cotman CW. Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo. Nature. 1988;332:360-361.
31. Ip NY, Yancopoulos G. The neurotrophins and CNTF: two families of collaborative neurotrophic factors. Annu Rev Neurosci. 1996; 19:491-515.
32. Cayouette M, Behn D, Sendtner M, Lachapelle P, Gravel C. Intraocular gene transfer of ciliary neurotrophic factor prevents death and increases responsiveness of rod photoreceptors in the retinal degeneration slow mouse. J Neurosci. 1998;18:9282-9293.
33. Silverman MS, Hughes SE. Photoreceptor rescue in the RCS rat without pigment epithelium transplantation. Curr Eye Res. 1990; 9:183-191.
34. Coggeshall RE, Lekan HA. Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J Comp Neurol. 1996;364:6-15.
35. Perry J, Du J, Kjeldbye H, Gouras P. The effects of bFGF on RCS rat eyes. Curr Eye Res. 1995;14:585-592.
36. Buj-Bello A, Buchman VL, Horton A, Rosenthal A, Davies AM. GDNF is an age-specific survival factor for sensory and autonomic neurons. Neuron. 1995;15:821-828.
37. Tomac A, Lindqvist E, Lin L-FH, et al. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature. 1995; 373:335-339.
38. Sanchez JE, Silos-Santiago I, Frisen J, He B, Lira SA, Barbacid M. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature. 1996;382:70-73.
39. Hellmich HL, Kos L, Cho ES, Mahon KA, Zimmer A. Embryonic expression of glial cell-line neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions. Mech Dev. 1996;54:95-105.
40. Jomary C, Thomas M, Grist J, et al. Expression patterns of neurturin and its receptor components in developing and degenerative mouse retina. Invest Ophthalmol Vis Sci. 1999;40:568-574.
41. Farber DB, Flannery JG, Bowes-Rickman C. The rd mouse story: seventy years of research on an animal model of inherited retinal degeneration. Prog Retinal Eye Res. 1994;13:31-64.
42. Jomary C, Vincent KA, Grist J, Neal MJ, Jones SE. Rescue of photoreceptor function by AAV-mediated gene transfer in a mouse model of inherited retinal degeneration. Gene Ther. 1997;4:683-690.
43. Lewin AS, Drenser KA, Hauswirth WW, et al. Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa. Nat Med. 1998;4:967-981.
44. Lewis GP, Erickson PA, Guerin CJ, Anderson DH, Fisher SK. Basic fibroblast growth factor: a possible regulator of proliferation and intermediate filament expression in the retina. J Neurosci. 1992; 12:3968-3978.
45. Cao W, Wen R, Li F, Cheng T, Steinberg RH. Induction of basic fibroblast growth factor mRNA by basic fibroblast growth factor in Müller cells. Invest Ophthalmol Vis Sci. 1997;38:1358-1366.
46. Noël WK. Differentiation, metabolic organization, and viability of visual cells. Arch Ophthalmol. 1958;60:702-731.
47. Yamasaki I, Mizuno K. Rhodopsin and ERG of hereditary dystrophic mice and experimental retinitis pigmentosa. Jpn J Ophthalmol. 1970;14:151-158.
48. Bonaventure N, Karli WP. Enhanced sensory convergence to the visual cortex in the rodless (rd/rd) mouse. Doc Ophthalmol. 1985; 61:97-103.
49. Mohand-Said S, Hicks D, Simonutti M, et al. Photoreceptor transplants increase host cone survival in the retinal degeneration (rd) mouse. Ophthalmic Res. 1997;29:290-297.
50. Mohand-Said S, Deudon-Combe A, Hicks D, et al. Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse. Proc Natl Acad Sci USA. 1998;95:8357-8362.
51. Wen R, Song Y, Cheng T, et al. Injury-induced upregulation of bFGF and CNTF mRNAs in the rat retina. J Neurosci. 1995;15: 7377-7385.