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Volumn 3, Issue 4-5, 2007, Pages 251-262

Hepatocellular stem cells

Author keywords

Hepatocellular progenitor stem cells; Oval cell; Regeneration

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; 5 (2,6 DICHLOROBENZYLSULFONYL) 3 [3,5 DIMETHYL 4 [2 (1 PYRROLIDINYLMETHYL) 1 PYRROLIDINYLCARBONYL] 1H PYRROL 2 YLMETHYLENE] 1,3 DIHYDRO 2H INDOL 2 ONE; ALBUMIN; ALPHA FETOPROTEIN; ANTINEOPLASTIC AGENT; BONE MORPHOGENETIC PROTEIN; CCAAT ENHANCER BINDING PROTEIN; CD34 ANTIGEN; CHROMOGRANIN A; CYTOKERATIN 19; CYTOKERATIN 7; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; LIGNAN DERIVATIVE; N (3 CHLOROPHENYL) 3 [3,5 DIMETHYL 4 (4 METHYL 1 PIPERAZINYLCARBONYL) 1H PYRROL 2 YLMETHYLENE] 2,3 DIHYDRO N METHYL 2 OXO 1H INDOLE 5 SULFONAMIDE; NVP AEW 541; PROTEIN SERINE THREONINE KINASE INHIBITOR; SB 208; SCATTER FACTOR; SEMAXANIB; SOMATOMEDIN; SORAFENIB; SU 11271; SU 11606; THY 1 ANTIGEN; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TYRPHOSTIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; WNT PROTEIN;

EID: 38449087864     PISSN: 15740153     EISSN: None     Source Type: Journal    
DOI: 10.3233/cbm-2007-34-509     Document Type: Article
Times cited : (8)

References (145)
  • 1
    • 33749017926 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
    • G.K. Abou-Alfa et al., Phase II study of sorafenib in patients with advanced hepatocellular carcinoma, J Clin Oncol 24(26) (2006), 4293-4300.
    • (2006) J Clin Oncol , vol.24 , Issue.26 , pp. 4293-4300
    • Abou-Alfa, G.K.1
  • 2
    • 0032964644 scopus 로고    scopus 로고
    • Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma
    • M. Abou-Shady et al., Transforming growth factor betas and their signaling receptors in human hepatocellular carcinoma, Am J Surg 177(3) (1999), 209-215.
    • (1999) Am J Surg , vol.177 , Issue.3 , pp. 209-215
    • Abou-Shady, M.1
  • 3
    • 0026801421 scopus 로고    scopus 로고
    • P. Akerman et al., Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy, Am J Physiol 263 4 Pt 1 (1992), G579-0585.
    • P. Akerman et al., Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy, Am J Physiol 263 4 Pt 1) (1992), G579-0585.
  • 4
    • 28544438991 scopus 로고    scopus 로고
    • Liver cancer: The told of stem cells
    • M.R. Alison and M.J. Lovell, Liver cancer: The told of stem cells, Cell Prolif 38(6) (2005), 407-421.
    • (2005) Cell Prolif , vol.38 , Issue.6 , pp. 407-421
    • Alison, M.R.1    Lovell, M.J.2
  • 5
    • 0028959114 scopus 로고
    • Transforming growth factor-beta 1 (TGF- beta 1) and TGF-beta 1 receptors in normal, cirrhotic, and neoplastic human livers
    • P. Bedossa et al., Transforming growth factor-beta 1 (TGF- beta 1) and TGF-beta 1 receptors in normal, cirrhotic, and neoplastic human livers, Hepatology 21(3) (1995), 760-766.
    • (1995) Hepatology , vol.21 , Issue.3 , pp. 760-766
    • Bedossa, P.1
  • 6
    • 0028239374 scopus 로고
    • Modulation of keratin 14 and alpha-fetoprotein expression during hepatic oval cell proliferation and liver regeneration
    • H.C. Bisgaard et al., Modulation of keratin 14 and alpha-fetoprotein expression during hepatic oval cell proliferation and liver regeneration, J Cell Physiol 159(3) (1994), 475-484.
    • (1994) J Cell Physiol , vol.159 , Issue.3 , pp. 475-484
    • Bisgaard, H.C.1
  • 7
    • 0027954225 scopus 로고
    • c-met mRNA overexpression in human hepatocellular carcinoma
    • L. Boix et al., c-met mRNA overexpression in human hepatocellular carcinoma, Hepatology 19(1) (1994), 88-91.
    • (1994) Hepatology , vol.19 , Issue.1 , pp. 88-91
    • Boix, L.1
  • 8
    • 33745552897 scopus 로고    scopus 로고
    • Dysregulation of growth factor signaling in human hepatocellular carcinoma
    • K. Breuhahn, T. Longerich and P. Schirmacher, Dysregulation of growth factor signaling in human hepatocellular carcinoma, Oncogene 25 27) (2006), 3787-3800.
    • (2006) Oncogene , vol.25 , Issue.27 , pp. 3787-3800
    • Breuhahn, K.1    Longerich, T.2    Schirmacher, P.3
  • 9
    • 0035001446 scopus 로고    scopus 로고
    • Expression of suppressors of cytokine signaling during liver regeneration
    • J.S. Campbel et al., Expression of suppressors of cytokine signaling during liver regeneration, J Clin Invest 107(10) (2001), 1285-1292.
    • (2001) J Clin Invest , vol.107 , Issue.10 , pp. 1285-1292
    • Campbel, J.S.1
  • 10
    • 33745924696 scopus 로고    scopus 로고
    • Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
    • T. Chiba et al., Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties, Hepatology 44 1 ) (2006), 240-251.
    • (2006) Hepatology , vol.44 , Issue.1 , pp. 240-251
    • Chiba, T.1
  • 11
    • 10744228765 scopus 로고    scopus 로고
    • A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo
    • J.G. Christensen et al., A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo, Cancer Res 63(21) (2003), 7345-7355.
    • (2003) Cancer Res , vol.63 , Issue.21 , pp. 7345-7355
    • Christensen, J.G.1
  • 12
    • 20144386856 scopus 로고    scopus 로고
    • Combination therapy enhances the inhibition of tumor growth with the fuUy human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871
    • B.D. Cohen et al., Combination therapy enhances the inhibition of tumor growth with the fuUy human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871, Clin Cancer Res 11 5) (2005), 2063-2073.
    • (2005) Clin Cancer Res , vol.11 , Issue.5 , pp. 2063-2073
    • Cohen, B.D.1
  • 13
    • 0029846756 scopus 로고    scopus 로고
    • Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice
    • D.E. Cressman et al., Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice, Science 274 5291) (1996), 1379-1383.
    • (1996) Science , vol.274 , Issue.5291 , pp. 1379-1383
    • Cressman, D.E.1
  • 14
    • 0036920045 scopus 로고    scopus 로고
    • Progenitor cells of the biliary epithelial cell lineage
    • H.A. Crosby et al., Progenitor cells of the biliary epithelial cell lineage, Semin Cell Dev Biol 13(6) (2002), 397-403.
    • (2002) Semin Cell Dev Biol , vol.13 , Issue.6 , pp. 397-403
    • Crosby, H.A.1
  • 15
    • 0030598681 scopus 로고    scopus 로고
    • TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in ft-msgenic mice
    • W. Cui et al., TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in ft-msgenic mice, Cell 86(4) (1996), 531-542.
    • (1996) Cell , vol.86 , Issue.4 , pp. 531-542
    • Cui, W.1
  • 16
    • 0029974338 scopus 로고    scopus 로고
    • Liver hepatocyte growth factor does not always correlate with hepatocellular proliferation in human liver lesions: Its specific receptor c-met does
    • A. D'Errico et al., Liver hepatocyte growth factor does not always correlate with hepatocellular proliferation in human liver lesions: Its specific receptor c-met does, Hepatology 24(1) (1996), 60-64.
    • (1996) Hepatology , vol.24 , Issue.1 , pp. 60-64
    • D'Errico, A.1
  • 17
    • 0027732935 scopus 로고
    • Activation, proliferation, and differentiation of progenitor cells into bepatocytes in the D-galactosamine model of liver regeneration
    • M.D. Dabeva and D.A. Shafritz, Activation, proliferation, and differentiation of progenitor cells into bepatocytes in the D-galactosamine model of liver regeneration, Am J Pathol 143 6) (1993), 1606-1620.
    • (1993) Am J Pathol , vol.143 , Issue.6 , pp. 1606-1620
    • Dabeva, M.D.1    Shafritz, D.A.2
  • 18
    • 0029031943 scopus 로고
    • Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors
    • A.T. De Souza et al., Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors, Oncogene 10(9) (1995), 1725-1729.
    • (1995) Oncogene , vol.10 , Issue.9 , pp. 1725-1729
    • De Souza, A.T.1
  • 19
    • 0026773152 scopus 로고
    • Ultrastructural characteristics of novel epithelial cell types identified in human pathologic liver specimens with chronic ductular reaction
    • R. De Vos and V. Desmet, Ultrastructural characteristics of novel epithelial cell types identified in human pathologic liver specimens with chronic ductular reaction, Am J Pathol 140(6) (1992), 1441-1450.
    • (1992) Am J Pathol , vol.140 , Issue.6 , pp. 1441-1450
    • De Vos, R.1    Desmet, V.2
  • 20
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • R. Derynck, R.J. Akhurst and A. Balmain, TGF-beta signaling in tumor suppression and cancer progression, Nat Genet 29(2) (2001), 117-129.
    • (2001) Nat Genet , vol.29 , Issue.2 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 22
    • 0033969934 scopus 로고    scopus 로고
    • Micrombule binding to Smads may regulate TGF beta activity
    • C. Dong et al., Micrombule binding to Smads may regulate TGF beta activity, Mol Cell 5(1) (2000), 27-34.
    • (2000) Mol Cell , vol.5 , Issue.1 , pp. 27-34
    • Dong, C.1
  • 23
    • 0024363412 scopus 로고
    • Different lineages of chemically induced hepatocellular carcinoma in rats defined by monoclonal antibodies
    • H.A. Dunsford et al., Different lineages of chemically induced hepatocellular carcinoma in rats defined by monoclonal antibodies, Cancer Res 49(17) (1989), 4894-4900.
    • (1989) Cancer Res , vol.49 , Issue.17 , pp. 4894-4900
    • Dunsford, H.A.1
  • 24
    • 0024413927 scopus 로고
    • Production of monoclonal antibodies to preneoplastic liver cell populations induced by chemical carcinogens in rats and to transplantable Morris hepatomas
    • H.A. Dunsford and S. Sell, Production of monoclonal antibodies to preneoplastic liver cell populations induced by chemical carcinogens in rats and to transplantable Morris hepatomas, Cancer Res 49 17) (1989), 4887-4893.
    • (1989) Cancer Res , vol.49 , Issue.17 , pp. 4887-4893
    • Dunsford, H.A.1    Sell, S.2
  • 25
    • 4644293033 scopus 로고    scopus 로고
    • Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell lines
    • E.A. Efimova et al., Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell lines, Eur Surg Res 36(5) (2004), 300-307.
    • (2004) Eur Surg Res , vol.36 , Issue.5 , pp. 300-307
    • Efimova, E.A.1
  • 26
    • 7044231396 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Recent trends in the United States
    • H.B. El-Serag, Hepatocellular carcinoma: Recent trends in the United States, Gastroenterology 127(5 Suppl 1) (2004), S27-S34.
    • (2004) Gastroenterology , vol.127 , Issue.5 SUPPL. 1
    • El-Serag, H.B.1
  • 27
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • H.B. El-Serag and A.C. Mason, Rising incidence of hepatocellular carcinoma in the United States, N Engl J Med 340(10) (1999 , 745-750.
    • (1999) N Engl J Med , vol.340 , Issue.10 , pp. 745-750
    • El-Serag, H.B.1    Mason, A.C.2
  • 28
    • 0025167745 scopus 로고
    • Common antigens of mouse oval and biliary epithelial cells. Expression on newly formed hepatocytes
    • N.V. Engelhardt et al., Common antigens of mouse oval and biliary epithelial cells. Expression on newly formed hepatocytes, Differentiation 45(1) (1990), 29-37.
    • (1990) Differentiation , vol.45 , Issue.1 , pp. 29-37
    • Engelhardt, N.V.1
  • 29
    • 0023442448 scopus 로고
    • A precursor-product relationship exists between oval cells and hepatocytes in rat liver
    • R.P. Evarts et al., A precursor-product relationship exists between oval cells and hepatocytes in rat liver, Carcinogenesis 8(11) (1987), 1737-1740.
    • (1987) Carcinogenesis , vol.8 , Issue.11 , pp. 1737-1740
    • Evarts, R.P.1
  • 30
    • 0024564630 scopus 로고
    • In vivo differentiation of rat liver oval cells into hepatocytes
    • R.P. Evarts et al., In vivo differentiation of rat liver oval cells into hepatocytes, Cancer Res 49(6) (1989), 1541-1547.
    • (1989) Cancer Res , vol.49 , Issue.6 , pp. 1541-1547
    • Evarts, R.P.1
  • 31
    • 0037853158 scopus 로고    scopus 로고
    • Regeneration of hepatocyte 'buds' in cirrhosis from intrabiliary stem cells
    • O. Falkowski et al., Regeneration of hepatocyte 'buds' in cirrhosis from intrabiliary stem cells, J Hepatol 39(3) (2003), 357-364.
    • (2003) J Hepatol , vol.39 , Issue.3 , pp. 357-364
    • Falkowski, O.1
  • 32
    • 84961012817 scopus 로고
    • Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylamino-fluorene, and 3′-methyl-4-dimethylaminoazobenzene
    • E. Farber, Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylamino-fluorene, and 3′-methyl-4-dimethylaminoazobenzene, Cancer Res 16(2) (1956), 142-148.
    • (1956) Cancer Res , vol.16 , Issue.2 , pp. 142-148
    • Farber, E.1
  • 33
    • 0021270821 scopus 로고
    • Mechanisms of cell injury with hepatotoxic chemicals
    • J.L. Farber and R.J. Gerson, Mechanisms of cell injury with hepatotoxic chemicals, Pharmacol Rev 36(2 Suppl) (1984), 71S-75S.
    • (1984) Pharmacol Rev , vol.36 , Issue.2 SUPPL.
    • Farber, J.L.1    Gerson, R.J.2
  • 34
    • 0032759120 scopus 로고    scopus 로고
    • Lessons from genetically engineered animal models. V. Knocking out genes to study liver regeneration: Present and future
    • N. Fausto, Lessons from genetically engineered animal models. V. Knocking out genes to study liver regeneration: Present and future, Am J Physiol 277(5 Pt 1) (1999), G917-G921.
    • (1999) Am J Physiol , vol.277 , Issue.5 PART 1
    • Fausto, N.1
  • 35
    • 2542601615 scopus 로고    scopus 로고
    • Liver regeneration and repair: Hepatocytes, progenitor cells, and stem cells
    • N. Fausto, Liver regeneration and repair: Hepatocytes, progenitor cells, and stem cells, Hepatology 39(6) (2004), 1477-1487.
    • (2004) Hepatology , vol.39 , Issue.6 , pp. 1477-1487
    • Fausto, N.1
  • 37
    • 0028914369 scopus 로고
    • Rapid DNA binding by nuclear factor kappa B in hepatocytes at the start of liver regeneration
    • M.J. FitzGerald et al., Rapid DNA binding by nuclear factor kappa B in hepatocytes at the start of liver regeneration, Cell Growth Differ 6(4) (1995), 417-427.
    • (1995) Cell Growth Differ , vol.6 , Issue.4 , pp. 417-427
    • FitzGerald, M.J.1
  • 38
    • 0029128586 scopus 로고
    • Glutamine synthetase and hepatocarcinogenesis
    • R. Gebhardt and G.M. Williams, Glutamine synthetase and hepatocarcinogenesis, Carcinogenesis 16(8) (1995), 1673-1681.
    • (1995) Carcinogenesis , vol.16 , Issue.8 , pp. 1673-1681
    • Gebhardt, R.1    Williams, G.M.2
  • 39
    • 0029097386 scopus 로고
    • Oval cell differentiation into hepatocytes in the acetylaminofluorene-treated regenerating rat liver
    • M. Golding et al., Oval cell differentiation into hepatocytes in the acetylaminofluorene-treated regenerating rat liver, Hepatology 22(4 Pt 1) (1995), 1243-1253.
    • (1995) Hepatology , vol.22 , Issue.4 PART 1 , pp. 1243-1253
    • Golding, M.1
  • 40
    • 0035136177 scopus 로고    scopus 로고
    • Expression of hepatocyte growth factor in human hepatocellular carcinoma
    • J. Guirouilh et al., Expression of hepatocyte growth factor in human hepatocellular carcinoma, J Hepatol 34(1) (2001), 78-83.
    • (2001) J Hepatol , vol.34 , Issue.1 , pp. 78-83
    • Guirouilh, J.1
  • 41
    • 0041384025 scopus 로고    scopus 로고
    • Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor
    • L. Guo et al., Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor, J Am Soc Mass Spectrom 14 9) (2003), 1022-1031.
    • (2003) J Am Soc Mass Spectrom , vol.14 , Issue.9 , pp. 1022-1031
    • Guo, L.1
  • 42
    • 9344245148 scopus 로고    scopus 로고
    • Transforming growth factor beta receptor I kinase inhibitor down-regulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment
    • T. Hayashi et al., Transforming growth factor beta receptor I kinase inhibitor down-regulates cytokine secretion and multiple myeloma cell growth in the bone marrow microenvironment, Clin Cancer Res 10 22) (2004), 7540-7546.
    • (2004) Clin Cancer Res , vol.10 , Issue.22 , pp. 7540-7546
    • Hayashi, T.1
  • 43
    • 0001276586 scopus 로고
    • Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal
    • G.M. Higgins and R.M. Anderson, Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal, Arch Pathol 12 (1931), 186-202.
    • (1931) Arch Pathol , vol.12 , pp. 186-202
    • Higgins, G.M.1    Anderson, R.M.2
  • 44
    • 0033087904 scopus 로고    scopus 로고
    • Expressions of epidermal growth factor family and its receptor in hepatocellular carcinoma cell lines: Relationship to cell proliferation
    • T. Hisaka et al., Expressions of epidermal growth factor family and its receptor in hepatocellular carcinoma cell lines: Relationship to cell proliferation, Int J Oncol 14(3) (1999), 453-460.
    • (1999) Int J Oncol , vol.14 , Issue.3 , pp. 453-460
    • Hisaka, T.1
  • 45
    • 0034077478 scopus 로고    scopus 로고
    • Differentiation status of rat ductal cells and ethionine-induced hepatic carcinomas defined with surface-reactive monoclonal antibodies
    • D.C. Hixson et al., Differentiation status of rat ductal cells and ethionine-induced hepatic carcinomas defined with surface-reactive monoclonal antibodies, Exp Mol Pathol 68(3) (2000), 152-169.
    • (2000) Exp Mol Pathol , vol.68 , Issue.3 , pp. 152-169
    • Hixson, D.C.1
  • 46
    • 4444341835 scopus 로고    scopus 로고
    • SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility
    • M.D. Hjelmeland et al., SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility, Mol Cancer Ther 3(6) (2004), 737-745.
    • (2004) Mol Cancer Ther , vol.3 , Issue.6 , pp. 737-745
    • Hjelmeland, M.D.1
  • 47
    • 0019849760 scopus 로고
    • Differentiation of the mouse hepatic primordium. II. Extrinsic origin of the haemopoietic cell line
    • E. Houssaint, Differentiation of the mouse hepatic primordium. II. Extrinsic origin of the haemopoietic cell line, Cell Differ 10 5) (1981), 243-252.
    • (1981) Cell Differ , vol.10 , Issue.5 , pp. 243-252
    • Houssaint, E.1
  • 48
    • 0026447566 scopus 로고
    • Occurrence of oval-type cells in hepatitis B virus-associated human hepatocarcinogenesis
    • C.C. Hsia et al., Occurrence of oval-type cells in hepatitis B virus-associated human hepatocarcinogenesis, Hepatology 16 6) (1992), 1327-1333.
    • (1992) Hepatology , vol.16 , Issue.6 , pp. 1327-1333
    • Hsia, C.C.1
  • 49
    • 0028342783 scopus 로고
    • Expression of hepatitis B surface and core antigens and transforming growth factor-alpha in "oval cells" of the liver in patients with hepatocellular carcinoma
    • C.C. Hsia, S.S. Thorgeirsson and E. Tabor, Expression of hepatitis B surface and core antigens and transforming growth factor-alpha in "oval cells" of the liver in patients with hepatocellular carcinoma, J Med Virol 43(3) (1994), 216-221.
    • (1994) J Med Virol , vol.43 , Issue.3 , pp. 216-221
    • Hsia, C.C.1    Thorgeirsson, S.S.2    Tabor, E.3
  • 50
    • 0027942871 scopus 로고
    • Expression of heparin-binding epidermal growth factor in human hepatocellular carcinoma
    • Y. Inui et al., Expression of heparin-binding epidermal growth factor in human hepatocellular carcinoma, Gastroenterology 107(6) (1994), 1799-1804.
    • (1994) Gastroenterology , vol.107 , Issue.6 , pp. 1799-1804
    • Inui, Y.1
  • 51
    • 0035819241 scopus 로고    scopus 로고
    • Increased secretion of tumour necrosis factor and interleukin 6 from isolated, perfused liver of rats after partial hepatectomy
    • M. Iwai et al., Increased secretion of tumour necrosis factor and interleukin 6 from isolated, perfused liver of rats after partial hepatectomy, Cytokine 13(1) (2001), 60-64.
    • (2001) Cytokine , vol.13 , Issue.1 , pp. 60-64
    • Iwai, M.1
  • 52
    • 0034805896 scopus 로고    scopus 로고
    • Activation of the IGF-II gene by HBV-X protein requires PKC and p44/p42 map kinase signalings
    • S. Kang-Park et al., Activation of the IGF-II gene by HBV-X protein requires PKC and p44/p42 map kinase signalings, Biochem Biophys Res Commun 283(2) (2001), 303-307.
    • (2001) Biochem Biophys Res Commun , vol.283 , Issue.2 , pp. 303-307
    • Kang-Park, S.1
  • 53
    • 0035899396 scopus 로고    scopus 로고
    • Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis
    • S. Kanzler et al., Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis, Oncogene 20(36) (2001), 5015-5024.
    • (2001) Oncogene , vol.20 , Issue.36 , pp. 5015-5024
    • Kanzler, S.1
  • 54
    • 0036016505 scopus 로고    scopus 로고
    • The effect of ischemia on the regeneration of the cholestatic liver. An experimental study
    • D. Karavias et al., The effect of ischemia on the regeneration of the cholestatic liver. An experimental study, Hepatogastroenterology 49(44) (2002), 456-460.
    • (2002) Hepatogastroenterology , vol.49 , Issue.44 , pp. 456-460
    • Karavias, D.1
  • 55
    • 28544436147 scopus 로고    scopus 로고
    • Inactivation of ELF/TGF-beta signaling in human gastrointestinal cancer
    • V. Katuri et al., Inactivation of ELF/TGF-beta signaling in human gastrointestinal cancer, Oncogene 24(54) (2005), 8012-8024.
    • (2005) Oncogene , vol.24 , Issue.54 , pp. 8012-8024
    • Katuri, V.1
  • 56
    • 0038636318 scopus 로고    scopus 로고
    • Tumor formation by genetic mutations in the components of the Wnt signaling pathway
    • A. Kikuchi, Tumor formation by genetic mutations in the components of the Wnt signaling pathway, Cancer Sci 94(3) (2003), 225-229.
    • (2003) Cancer Sci , vol.94 , Issue.3 , pp. 225-229
    • Kikuchi, A.1
  • 57
    • 0034569179 scopus 로고    scopus 로고
    • Expression of transforming growth factor beta-1 in chronic hepatitis and hepatocellular carcinoma associated with hepatitis C virus infection
    • H.G. Kim et al., Expression of transforming growth factor beta-1 in chronic hepatitis and hepatocellular carcinoma associated with hepatitis C virus infection, Korean J Intern Med 15(3) (2000), 165-170.
    • (2000) Korean J Intern Med , vol.15 , Issue.3 , pp. 165-170
    • Kim, H.G.1
  • 58
    • 0000979718 scopus 로고
    • Studies on the carcinogenic chemical substances
    • R. Kinosita, Studies on the carcinogenic chemical substances, Sic Oathol jpn 27 (1937), 665-727.
    • (1937) Sic Oathol jpn , vol.27 , pp. 665-727
    • Kinosita, R.1
  • 59
    • 0030825110 scopus 로고    scopus 로고
    • Expression of transforming growth factor alpha and epidermal growth factor receptor in human hepatocellular carcinoma
    • S. Kira et al., Expression of transforming growth factor alpha and epidermal growth factor receptor in human hepatocellular carcinoma, Liver 17(4) (1997), 177-182.
    • (1997) Liver , vol.17 , Issue.4 , pp. 177-182
    • Kira, S.1
  • 60
    • 0242378079 scopus 로고    scopus 로고
    • Liver regeneration
    • L.G. Koniaris et al., Liver regeneration, J Am Coll Surg 197 4) (2003), 634-659.
    • (2003) J Am Coll Surg , vol.197 , Issue.4 , pp. 634-659
    • Koniaris, L.G.1
  • 61
    • 0031227543 scopus 로고    scopus 로고
    • Antisense insulin-like growth factor I transferred into a rat hepatoma cell line inhibits tumorigenesis by modulating major histocompatibility complex I cell surface expression
    • C. Lafarge-Frayssinet et al., Antisense insulin-like growth factor I transferred into a rat hepatoma cell line inhibits tumorigenesis by modulating major histocompatibility complex I cell surface expression, Cancer Gene Ther 4(5) (1997), 276-285.
    • (1997) Cancer Gene Ther , vol.4 , Issue.5 , pp. 276-285
    • Lafarge-Frayssinet, C.1
  • 62
    • 0014198050 scopus 로고
    • Role of the mesoderm in the induction of the synthesis of glycogen during differentiation of the hepatic endoderm
    • N. Le Douarin and E. Houssaint, Role of the mesoderm in the induction of the synthesis of glycogen during differentiation of the hepatic endoderm, C R Acad Sci Hebd Seances Acad Sci D 264(15) (1967), 1872-1874.
    • (1967) C R Acad Sci Hebd Seances Acad Sci D , vol.264 , Issue.15 , pp. 1872-1874
    • Le Douarin, N.1    Houssaint, E.2
  • 63
    • 0035837055 scopus 로고    scopus 로고
    • Hepatitis C virus core protein transactivates insulin-like growth factor II gene transcription through acting concurrently on Egr1 and Sp1 sites
    • S. Lee, U. Park and Y.I. Lee, Hepatitis C virus core protein transactivates insulin-like growth factor II gene transcription through acting concurrently on Egr1 and Sp1 sites, Virology 283(2) (2001), 167-177.
    • (2001) Virology , vol.283 , Issue.2 , pp. 167-177
    • Lee, S.1    Park, U.2    Lee, Y.I.3
  • 64
    • 0032493107 scopus 로고    scopus 로고
    • The human hepatitis B virus transactivator X gene product regulates Sp1 mediated transcription of an insulin-like growth factor II promoter 4
    • Y.I. Lee et al., The human hepatitis B virus transactivator X gene product regulates Sp1 mediated transcription of an insulin-like growth factor II promoter 4, Oncogene 16(18) (1998), 2367-2380.
    • (1998) Oncogene , vol.16 , Issue.18 , pp. 2367-2380
    • Lee, Y.I.1
  • 65
    • 0025873457 scopus 로고
    • Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine
    • J.M. Lemire, N. Shiojiri and N. Fausto, Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine, Am J Pathol 139(3) (1991), 535-552.
    • (1991) Am J Pathol , vol.139 , Issue.3 , pp. 535-552
    • Lemire, J.M.1    Shiojiri, N.2    Fausto, N.3
  • 66
    • 0033645595 scopus 로고    scopus 로고
    • Deep intralobular extension of human hepatic 'progenitor cells' correlates with parenchymal inflammation in chronic viral hepatitis: Can 'progenitor cells' migrate?
    • L. Libbrecht et al., Deep intralobular extension of human hepatic 'progenitor cells' correlates with parenchymal inflammation in chronic viral hepatitis: Can 'progenitor cells' migrate? J Pathol 192 3) (2000), 373-378.
    • (2000) J Pathol , vol.192 , Issue.3 , pp. 373-378
    • Libbrecht, L.1
  • 67
    • 12144260822 scopus 로고    scopus 로고
    • Factors of transforming growth factor beta signaling are co-regulated in human hepatocellular carcinoma
    • T. Longerich et al., Factors of transforming growth factor beta signaling are co-regulated in human hepatocellular carcinoma, Virchows Arch 445(6) (2004), 589-596.
    • (2004) Virchows Arch , vol.445 , Issue.6 , pp. 589-596
    • Longerich, T.1
  • 68
    • 0032964899 scopus 로고    scopus 로고
    • Oval cell numbers in human chronic liver diseases are directly related to disease severity
    • K.N. Lowes et al., Oval cell numbers in human chronic liver diseases are directly related to disease severity, Am J Pathol 154(2) (1999), 537-541.
    • (1999) Am J Pathol , vol.154 , Issue.2 , pp. 537-541
    • Lowes, K.N.1
  • 69
    • 0031835595 scopus 로고    scopus 로고
    • Microsatellite instability and loss of heterozygosity at DNA mismatch repair gene loci occurs during hepatic carcinogenesis
    • G.A. Macdonald et al., Microsatellite instability and loss of heterozygosity at DNA mismatch repair gene loci occurs during hepatic carcinogenesis, Hepatology 28(1) (1998), 90-97.
    • (1998) Hepatology , vol.28 , Issue.1 , pp. 90-97
    • Macdonald, G.A.1
  • 70
  • 71
    • 11144299533 scopus 로고    scopus 로고
    • Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-sppctrin, in primary biliary cirrhosis
    • B. Mishra et al., Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-sppctrin, in primary biliary cirrhosis, Liver Int 24(6) (2004), 637-645.
    • (2004) Liver Int , vol.24 , Issue.6 , pp. 637-645
    • Mishra, B.1
  • 72
    • 0033552955 scopus 로고    scopus 로고
    • Elf3 encodes a novel 200-kD beta-spectrin: Role in liver development
    • L. Mishra et al., Elf3 encodes a novel 200-kD beta-spectrin: Role in liver development, Oncogene 18(2) (1999), 353-364.
    • (1999) Oncogene , vol.18 , Issue.2 , pp. 353-364
    • Mishra, L.1
  • 73
    • 24644458638 scopus 로고    scopus 로고
    • The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer
    • L. Mishra et al., The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer, Oncogene 24(37) (2005), 5775-5789.
    • (2005) Oncogene , vol.24 , Issue.37 , pp. 5775-5789
    • Mishra, L.1
  • 74
    • 12144290914 scopus 로고    scopus 로고
    • Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
    • C.S. Mitsiades et al., Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors, Cancer Cell 5(3) (2004), 221-230.
    • (2004) Cancer Cell , vol.5 , Issue.3 , pp. 221-230
    • Mitsiades, C.S.1
  • 75
    • 16244373665 scopus 로고    scopus 로고
    • Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade-results of an explorative. CGH meta-analysis
    • P. Moinzadeh et al., Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade-results of an explorative. CGH meta-analysis, Br J Cancer 92(5) (2005), 935-941.
    • (2005) Br J Cancer , vol.92 , Issue.5 , pp. 935-941
    • Moinzadeh, P.1
  • 76
    • 0036546980 scopus 로고    scopus 로고
    • Neural induction, the default model and embryonic stem cells
    • I. Munoz-Sanjuan and A.H. Brivanlou, Neural induction, the default model and embryonic stem cells, Nat Rev Neurosci 3(4) (2002), 271-280.
    • (2002) Nat Rev Neurosci , vol.3 , Issue.4 , pp. 271-280
    • Munoz-Sanjuan, I.1    Brivanlou, A.H.2
  • 77
    • 0028291370 scopus 로고
    • Expression of hepatic transcription factors during liver development and oval cell differentiation
    • P. Nagy, H.C. Bisgaard and S.S. Thorgeirsson, Expression of hepatic transcription factors during liver development and oval cell differentiation, J Cell Biol 126(1) (1994), 223-233.
    • (1994) J Cell Biol , vol.126 , Issue.1 , pp. 223-233
    • Nagy, P.1    Bisgaard, H.C.2    Thorgeirsson, S.S.3
  • 78
    • 0024634991 scopus 로고
    • Growth factor and growth inhibitor for hepatocyte proliferation
    • T. Nakamura, Growth factor and growth inhibitor for hepatocyte proliferation, Gan To Kagaku Ryoho 16(3 Pt 2) (1989), 481-488.
    • (1989) Gan To Kagaku Ryoho , vol.16 , Issue.3 PART 2 , pp. 481-488
    • Nakamura, T.1
  • 79
    • 0030683506 scopus 로고    scopus 로고
    • Human hepatic myofibroblasts increase invasiveness of hepatoccellular carrinoma cells: Evidence for a role of hepatocyte growth factor
    • V. Neaud et al., Human hepatic myofibroblasts increase invasiveness of hepatoccellular carrinoma cells: Evidence for a role of hepatocyte growth factor, Hepatology 26(6) (1997), 1458-1466.
    • (1997) Hepatology , vol.26 , Issue.6 , pp. 1458-1466
    • Neaud, V.1
  • 80
    • 0032885751 scopus 로고    scopus 로고
    • Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation
    • J.T. Nhieu et al., Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation, Am J Pathol 155(3) (1999), 703-710.
    • (1999) Am J Pathol , vol.155 , Issue.3 , pp. 703-710
    • Nhieu, J.T.1
  • 81
    • 0031857555 scopus 로고    scopus 로고
    • Increased expression of TGF-beta receptors associated with increased sensitivity to TGF-beta-mediated growth inhibition
    • Changes in TGF-beta receptors of rat hepatocytes during primary culture and liver regeneration
    • Y. Nishikawa, M. Wang and B.I. Carr, Changes in TGF-beta receptors of rat hepatocytes during primary culture and liver regeneration: Increased expression of TGF-beta receptors associated with increased sensitivity to TGF-beta-mediated growth inhibition, J Cell Physiol 176 3) (1998), 612-623.
    • (1998) J Cell Physiol , vol.176 , Issue.3 , pp. 612-623
    • Nishikawa, Y.1    Wang, M.2    Carr, B.I.3
  • 82
    • 0032547895 scopus 로고    scopus 로고
    • TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis
    • M. Oft, K.H. Heider and H. Beug, TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis, Curr Biol 8(23) (1998), 1243-1252.
    • (1998) Curr Biol , vol.8 , Issue.23 , pp. 1243-1252
    • Oft, M.1    Heider, K.H.2    Beug, H.3
  • 83
    • 18344372735 scopus 로고    scopus 로고
    • M6P/IGF2R turnor suppressor gene mutated in hepatocellular carcinomas in Japan
    • Y. Oka et al., M6P/IGF2R turnor suppressor gene mutated in hepatocellular carcinomas in Japan, Hepatology 35(5) (2002), 1153-1163.
    • (2002) Hepatology , vol.35 , Issue.5 , pp. 1153-1163
    • Oka, Y.1
  • 84
    • 16244391814 scopus 로고    scopus 로고
    • Rat hepato-proliferin revealed the status of a complete hepatomitogen in human hepatoma cells
    • M.M. Oosthuizen, N. Ndaba and J.A. Myburgh, Rat hepato-proliferin revealed the status of a complete hepatomitogen in human hepatoma cells, Transplant Proc 37(1) (2005), 89-92.
    • (2005) Transplant Proc , vol.37 , Issue.1 , pp. 89-92
    • Oosthuizen, M.M.1    Ndaba, N.2    Myburgh, J.A.3
  • 85
    • 0030715611 scopus 로고    scopus 로고
    • Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes
    • K. Overturf et al., Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes, Am J Pathol 151(5) (1997), 1273-1280.
    • (1997) Am J Pathol , vol.151 , Issue.5 , pp. 1273-1280
    • Overturf, K.1
  • 86
    • 0029875835 scopus 로고    scopus 로고
    • Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinacmia type I
    • K. Overturf et al., Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinacmia type I, Nat Genet 12(3) (1996), 266-273.
    • (1996) Nat Genet , vol.12 , Issue.3 , pp. 266-273
    • Overturf, K.1
  • 87
    • 33746253919 scopus 로고    scopus 로고
    • Prometheus' challenge: Molecular, cellular and systemic aspects of liver regeneration
    • P.S. Pahlavan et al., Prometheus' challenge: Molecular, cellular and systemic aspects of liver regeneration, J Surg Res 134(2) (2006), 238-251.
    • (2006) J Surg Res , vol.134 , Issue.2 , pp. 238-251
    • Pahlavan, P.S.1
  • 88
    • 1842431049 scopus 로고    scopus 로고
    • Expression of Smad7 in hepatocellular carcinoma and dysplastic nodules: Resistance mechanism to transforming growth factor-beta
    • Y.N. Park et al., Expression of Smad7 in hepatocellular carcinoma and dysplastic nodules: Resistance mechanism to transforming growth factor-beta, Hepatogastroenteralogy 51(56) (2004), 396-400.
    • (2004) Hepatogastroenteralogy , vol.51 , Issue.56 , pp. 396-400
    • Park, Y.N.1
  • 89
    • 0033553591 scopus 로고    scopus 로고
    • Bone marrow as a potential source of hepatic oval cells
    • B.E. Petersen et al., Bone marrow as a potential source of hepatic oval cells, Science 284(5417) (1999), 1168-1170.
    • (1999) Science , vol.284 , Issue.5417 , pp. 1168-1170
    • Petersen, B.E.1
  • 90
    • 0037372738 scopus 로고    scopus 로고
    • Mouse A6-positive hepatic oval cells also express several hematopoietic stem cell markers
    • B.E. Petersen et al., Mouse A6-positive hepatic oval cells also express several hematopoietic stem cell markers, Hepatology 37(3) (2003), 632-640.
    • (2003) Hepatology , vol.37 , Issue.3 , pp. 632-640
    • Petersen, B.E.1
  • 91
    • 0025641727 scopus 로고
    • Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt
    • C.S. Potten and M. Loeffler, Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt, Development 110(4) (1990), 1001-1020.
    • (1990) Development , vol.110 , Issue.4 , pp. 1001-1020
    • Potten, C.S.1    Loeffler, M.2
  • 92
    • 0031303927 scopus 로고    scopus 로고
    • Transforming growth factor-beta and cancer: A love-hate relationship?
    • M. Reiss, Transforming growth factor-beta and cancer: A love-hate relationship? Oncol Res 9(9) (1997), 447-457.
    • (1997) Oncol Res , vol.9 , Issue.9 , pp. 447-457
    • Reiss, M.1
  • 93
    • 0028353410 scopus 로고
    • Replacement of diseased mouse liver by hepatic cell transplantation
    • J.A. Rhim et al., Replacement of diseased mouse liver by hepatic cell transplantation, Science 263(5150) (1994), 1149-1152.
    • (1994) Science , vol.263 , Issue.5150 , pp. 1149-1152
    • Rhim, J.A.1
  • 94
    • 20344366296 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Molecular pathways and new therapeutic targets
    • L.R. Roberts and G.J. Gores, Hepatocellular carcinoma: Molecular pathways and new therapeutic targets, Semin Liver Dis 25(2) (2005), 212-225.
    • (2005) Semin Liver Dis , vol.25 , Issue.2 , pp. 212-225
    • Roberts, L.R.1    Gores, G.J.2
  • 95
    • 33744941608 scopus 로고    scopus 로고
    • Different types of liver progenitor cells and their niches
    • T. Roskams, Different types of liver progenitor cells and their niches, J Hepatol 45(1) (2006), 1-4.
    • (2006) J Hepatol , vol.45 , Issue.1 , pp. 1-4
    • Roskams, T.1
  • 96
    • 33745533559 scopus 로고    scopus 로고
    • Liver stem cells and their implication in hepato-cellular and cholangiocarcinoma
    • T. Roskams, Liver stem cells and their implication in hepato-cellular and cholangiocarcinoma, Oncogene 25(27) (2006), 3818-3822.
    • (2006) Oncogene , vol.25 , Issue.27 , pp. 3818-3822
    • Roskams, T.1
  • 97
    • 0042033294 scopus 로고    scopus 로고
    • Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease
    • T. Roskams et al., Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease, Am J Pathol 163(4) (2003), 1301-1311.
    • (2003) Am J Pathol , vol.163 , Issue.4 , pp. 1301-1311
    • Roskams, T.1
  • 98
    • 0345731220 scopus 로고    scopus 로고
    • Progenitor cells in diseased human liver
    • T.A. Roskams, L. Libbrecht and V.J. Desmet, Progenitor cells in diseased human liver, Semin Liver Dis 23(4) (2003), 385-396.
    • (2003) Semin Liver Dis , vol.23 , Issue.4 , pp. 385-396
    • Roskams, T.A.1    Libbrecht, L.2    Desmet, V.J.3
  • 99
    • 2542595537 scopus 로고    scopus 로고
    • Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers
    • T.A. Roskams et al., Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers, Hepatology 39(6) (2004), 1739-1745.
    • (2004) Hepatology , vol.39 , Issue.6 , pp. 1739-1745
    • Roskams, T.A.1
  • 100
    • 0034840950 scopus 로고    scopus 로고
    • Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
    • A. Ryo et al., Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC, Nat Cell Biol 3(9) (2001), 793-801.
    • (2001) Nat Cell Biol , vol.3 , Issue.9 , pp. 793-801
    • Ryo, A.1
  • 101
    • 0037308651 scopus 로고    scopus 로고
    • A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I
    • D. Sachdev et al., A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I, Cancer Res 63(3) (2003), 627-635.
    • (2003) Cancer Res , vol.63 , Issue.3 , pp. 627-635
    • Sachdev, D.1
  • 102
    • 0025781894 scopus 로고
    • Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene
    • E.P. Sandgren et al., Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene, Cell 66 2) (1991), 245-256.
    • (1991) Cell , vol.66 , Issue.2 , pp. 245-256
    • Sandgren, E.P.1
  • 103
    • 0030609894 scopus 로고    scopus 로고
    • TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes
    • L.P. Sanford et al., TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes, Development 124(13) (1997), 2659-2670.
    • (1997) Development , vol.124 , Issue.13 , pp. 2659-2670
    • Sanford, L.P.1
  • 104
    • 0027999434 scopus 로고
    • Cell behavior in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations
    • C. Sarraf et al., Cell behavior in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations, Am J Pathol 145(5) (1994), 1114-1126.
    • (1994) Am J Pathol , vol.145 , Issue.5 , pp. 1114-1126
    • Sarraf, C.1
  • 105
    • 0034088858 scopus 로고    scopus 로고
    • AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
    • S. Satoh et al., AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1, Nat Genet 24(3) (2000), 245 250.
    • (2000) Nat Genet , vol.24 , Issue.3 , pp. 245-250
    • Satoh, S.1
  • 106
    • 0035075433 scopus 로고    scopus 로고
    • Nodal signaliag and the zebrafish organizer
    • A.F. Schier and W.S. Talbot, Nodal signaliag and the zebrafish organizer, Int J Dev Biol 45(1) (2001), 289-297.
    • (2001) Int J Dev Biol , vol.45 , Issue.1 , pp. 289-297
    • Schier, A.F.1    Talbot, W.S.2
  • 107
    • 17744417798 scopus 로고    scopus 로고
    • Blockage of insulin-like growth factor-I receptor inhibits the growth cf Ewing's sarcoma in athymic mice
    • K. Scotlandi et al., Blockage of insulin-like growth factor-I receptor inhibits the growth cf Ewing's sarcoma in athymic mice, Cancer Res 58(18) (1998), 4127-4131.
    • (1998) Cancer Res , vol.58 , Issue.18 , pp. 4127-4131
    • Scotlandi, K.1
  • 108
    • 20944447905 scopus 로고    scopus 로고
    • Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors
    • K. Scotlandi et al., Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors, Cancer Res 65(9) (2005), 3868-3876.
    • (2005) Cancer Res , vol.65 , Issue.9 , pp. 3868-3876
    • Scotlandi, K.1
  • 109
    • 0035120616 scopus 로고    scopus 로고
    • Heterogeneity and plasticity of hepatocyte lineage cells
    • S. Sell, Heterogeneity and plasticity of hepatocyte lineage cells, Hepatology 33(3) (2001), 738-750.
    • (2001) Hepatology , vol.33 , Issue.3 , pp. 738-750
    • Sell, S.1
  • 110
    • 0019519660 scopus 로고
    • Autoradiography of "oval cells" appearing rapidly in the livers of rats fed N-2-fluorenylacetamide in a choline, devoid diet
    • S. Sell, K. Osborn and H.L. Leffert, Autoradiography of "oval cells" appearing rapidly in the livers of rats fed N-2-fluorenylacetamide in a choline, devoid diet, Carcinogenesis 2(1) (1981), 7-14.
    • (1981) Carcinogenesis , vol.2 , Issue.1 , pp. 7-14
    • Sell, S.1    Osborn, K.2    Leffert, H.L.3
  • 111
    • 0024412841 scopus 로고
    • Development of intrahepatic bile ducts in humans. Immunohistochemical study using monoclcnal cytokeratin antibodies
    • K.D. Shah and M.A. Gerber, Development of intrahepatic bile ducts in humans. Immunohistochemical study using monoclcnal cytokeratin antibodies, Arch Pathol Lab Wed 113(10) (1989), 1135-1138.
    • (1989) Arch Pathol Lab Wed , vol.113 , Issue.10 , pp. 1135-1138
    • Shah, K.D.1    Gerber, M.A.2
  • 112
    • 0018765267 scopus 로고
    • Effects of a choline-devoid diet on the emergence of gamma-glutamyltranspeptidase-positive foci in the liver of carcinogen-treated rats
    • H. Shinozuka et al., Effects of a choline-devoid diet on the emergence of gamma-glutamyltranspeptidase-positive foci in the liver of carcinogen-treated rats, Cancer Res 39(7 Pt 1) (1979), 2515-2521.
    • (1979) Cancer Res , vol.39 , Issue.7 PART 1 , pp. 2515-2521
    • Shinozuka, H.1
  • 113
    • 0021213136 scopus 로고
    • Isolation and partial characterizations of oval and hyperplastic bile ductular cell-enriched populations from the livers of carcinogen and noncarcinogen-treated rats
    • A.E. Sirica and H.P. Cihla, Isolation and partial characterizations of oval and hyperplastic bile ductular cell-enriched populations from the livers of carcinogen and noncarcinogen-treated rats, Cancer Res 44(8) (1984), 3454-3466.
    • (1984) Cancer Res , vol.44 , Issue.8 , pp. 3454-3466
    • Sirica, A.E.1    Cihla, H.P.2
  • 114
    • 0017692938 scopus 로고
    • Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis
    • D.B. Solt, A. Medline and E. Farber, Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis, Am J Pathol 88 3) (1977), 595-618.
    • (1977) Am J Pathol , vol.88 , Issue.3 , pp. 595-618
    • Solt, D.B.1    Medline, A.2    Farber, E.3
  • 115
    • 0023814295 scopus 로고
    • Transforming growth factor-beta: New chemical forms and new biological roles
    • M.B. Sporn and A.B. Roberts, Transforming growth factor-beta: New chemical forms and new biological roles, Biofactors 1(1) (1988), 89-93.
    • (1988) Biofactors , vol.1 , Issue.1 , pp. 89-93
    • Sporn, M.B.1    Roberts, A.B.2
  • 116
    • 0013898010 scopus 로고
    • Cell population dynamics in the liver. A review of quantitative morphological techniques applied to the study of physiological and pathological growth
    • J.W. Steiner, Z.M. Perz and L.B. Taichman, Cell population dynamics in the liver. A review of quantitative morphological techniques applied to the study of physiological and pathological growth, Exp Mol Pathol 5(2) (1966), 146-181.
    • (1966) Exp Mol Pathol , vol.5 , Issue.2 , pp. 146-181
    • Steiner, J.W.1    Perz, Z.M.2    Taichman, L.B.3
  • 117
    • 76549226894 scopus 로고
    • Histochemical studies of mouse liver after single feeding of carbon tetrachloride
    • R.E. Stowell and C.S. Lee, Histochemical studies of mouse liver after single feeding of carbon tetrachloride, AMA Arch Pathol 50 5) (1950), 519-537.
    • (1950) AMA Arch Pathol , vol.50 , Issue.5 , pp. 519-537
    • Stowell, R.E.1    Lee, C.S.2
  • 118
    • 0034107193 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor-induced intracellular signalling
    • K.A. Stuart et al., Hepatocyte growth factor/scatter factor-induced intracellular signalling, Int J Exp Pathol 81(1) (2000), 17-30.
    • (2000) Int J Exp Pathol , vol.81 , Issue.1 , pp. 17-30
    • Stuart, K.A.1
  • 119
    • 0029100622 scopus 로고
    • Transforming growth factor-beta receptors and mannose 6-phosphate/insulin-like growth factor-II receptor expression in human hepatocellular carcirnoma
    • S.R. Sue et al., Transforming growth factor-beta receptors and mannose 6-phosphate/insulin-like growth factor-II receptor expression in human hepatocellular carcirnoma, Ann Surg 222(2) (1995), 171-178.
    • (1995) Ann Surg , vol.222 , Issue.2 , pp. 171-178
    • Sue, S.R.1
  • 120
    • 0037462502 scopus 로고    scopus 로고
    • Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice
    • Y. Tang et al., Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice, Science 299(5606) (2003), 574-577.
    • (2003) Science , vol.299 , Issue.5606 , pp. 574-577
    • Tang, Y.1
  • 121
    • 20144378766 scopus 로고    scopus 로고
    • Transforming growth factor-beta suppresses nonmetastatic, colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis
    • Y. Tang et al., Transforming growth factor-beta suppresses nonmetastatic, colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis, Cancer Res 65(10) (2005), 4228-4237.
    • (2005) Cancer Res , vol.65 , Issue.10 , pp. 4228-4237
    • Tang, Y.1
  • 122
    • 0037130449 scopus 로고    scopus 로고
    • Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
    • K. Taniguchi et al., Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas, Oncogene 21(31) (2002), 4863-4871.
    • (2002) Oncogene , vol.21 , Issue.31 , pp. 4863-4871
    • Taniguchi, K.1
  • 123
    • 5044232017 scopus 로고    scopus 로고
    • Liver regeneration: From myth to mechanism
    • R. Taub, Liver regeneration: From myth to mechanism, Nat Rev Mol Cell Biol 5(10) (2004), 836-847.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , Issue.10 , pp. 836-847
    • Taub, R.1
  • 124
    • 0033867263 scopus 로고    scopus 로고
    • u-PA and c-MET mRNA expression is co-ordinately enhanced while hepatocyte growth factor mRNA is down-regulated in human hepatocellular carcinoma
    • D. Tavian et al., u-PA and c-MET mRNA expression is co-ordinately enhanced while hepatocyte growth factor mRNA is down-regulated in human hepatocellular carcinoma, Int J Cancer 87(5) (2000), 644-649.
    • (2000) Int J Cancer , vol.87 , Issue.5 , pp. 644-649
    • Tavian, D.1
  • 125
    • 0029927456 scopus 로고    scopus 로고
    • Dual phenotypic expression of hepatocytes and bile ductular markers in developing and preneoplastic rat liver
    • L.B. Tee et al., Dual phenotypic expression of hepatocytes and bile ductular markers in developing and preneoplastic rat liver, Carcinogenesis 17(2) (1996), 251-259.
    • (1996) Carcinogenesis , vol.17 , Issue.2 , pp. 251-259
    • Tee, L.B.1
  • 126
    • 0032721682 scopus 로고    scopus 로고
    • The canals of Hering and hepatic stem cells in humans
    • N.D. Theise et al., The canals of Hering and hepatic stem cells in humans, Hepatology 30(6) (1999), 1425-1433.
    • (1999) Hepatology , vol.30 , Issue.6 , pp. 1425-1433
    • Theise, N.D.1
  • 127
    • 14944378875 scopus 로고    scopus 로고
    • D. Tosh and A. Strain, Liver stem cells - prospects for clinical use, J Hepatol 42(Suppl 1) (2005), S75-S84.
    • D. Tosh and A. Strain, Liver stem cells - prospects for clinical use, J Hepatol 42(Suppl 1) (2005), S75-S84.
  • 128
    • 0030051525 scopus 로고    scopus 로고
    • Acute-phase response factor, increased binding, and target gene transcription during liver regenera tion
    • C. Trautwein et al., Acute-phase response factor, increased binding, and target gene transcription during liver regenera tion, Gastroenterology 110(6) (1996), 1854-1862.
    • (1996) Gastroenterology , vol.110 , Issue.6 , pp. 1854-1862
    • Trautwein, C.1
  • 129
    • 0030907636 scopus 로고    scopus 로고
    • Clinical relevance of transforming growth factor-beta 1 in the urine of patients with hepatocellular carcinoma
    • J.F. Tsai et al., Clinical relevance of transforming growth factor-beta 1 in the urine of patients with hepatocellular carcinoma, Medicine (Baltimore) 76(3) (1997), 213-226.
    • (1997) Medicine (Baltimore) , vol.76 , Issue.3 , pp. 213-226
    • Tsai, J.F.1
  • 130
    • 0032428684 scopus 로고    scopus 로고
    • SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor
    • T. Tsukazaki et al., SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor, Cell 95(6) (1998), 779-791.
    • (1998) Cell , vol.95 , Issue.6 , pp. 779-791
    • Tsukazaki, T.1
  • 131
    • 0242609884 scopus 로고    scopus 로고
    • Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence
    • T. Uenishi et al., Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence, Cancer Sci 94(10) (2003), 851-857.
    • (2003) Cancer Sci , vol.94 , Issue.10 , pp. 851-857
    • Uenishi, T.1
  • 132
    • 0034712048 scopus 로고    scopus 로고
    • Why stem cells?
    • D. van der Kooy and S. Weiss, Why stem cells? Science 287 5457) (2000), 1439-1441.
    • (2000) Science , vol.287 , Issue.5457 , pp. 1439-1441
    • van der Kooy, D.1    Weiss, S.2
  • 133
    • 0024213059 scopus 로고
    • A keratin-immunohistochemical study
    • The development of the intrahepatic bile ducts in man
    • P. Van Eyken et al., The development of the intrahepatic bile ducts in man: A keratin-immunohistochemical study, Hepatology 8(6) (1988), 1586-1595.
    • (1988) Hepatology , vol.8 , Issue.6 , pp. 1586-1595
    • Van Eyken, P.1
  • 134
    • 0023680892 scopus 로고
    • A cytokeratin-immunohistochemical study
    • Intrahepatic bile duct development in the rat
    • P. Van Eyken, R. Sciot and V. Desmet, Intrahepatic bile duct development in the rat: A cytokeratin-immunohistochemical study, Lab Invest 59(1) (1988), 52-59.
    • (1988) Lab Invest , vol.59 , Issue.1 , pp. 52-59
    • Van Eyken, P.1    Sciot, R.2    Desmet, V.3
  • 135
    • 0023894776 scopus 로고
    • Cytokeratin expression in hepatocellular carcinoma: An immunohistochemical study
    • P. Van Eyken et al., Cytokeratin expression in hepatocellular carcinoma: an immunohistochemical study, Hum Pathol 19(5) (1988), 562-568.
    • (1988) Hum Pathol , vol.19 , Issue.5 , pp. 562-568
    • Van Eyken, P.1
  • 136
    • 0035019883 scopus 로고    scopus 로고
    • Hepatic stem cells: A review
    • C.J. Vessey and P.M. de la Hall, Hepatic stem cells: A review, Pathology 33(2) (2001), 130-141.
    • (2001) Pathology , vol.33 , Issue.2 , pp. 130-141
    • Vessey, C.J.1    de la Hall, P.M.2
  • 137
    • 0035144232 scopus 로고    scopus 로고
    • Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver
    • K.E. Wack et al., Sinusoidal ultrastructure evaluated during the revascularization of regenerating rat liver, Hepatology 33 2) (2001), 363-378.
    • (2001) Hepatology , vol.33 , Issue.2 , pp. 363-378
    • Wack, K.E.1
  • 138
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • A. Wodarz and R. Nusse, Mechanisms of Wnt signaling in development, Annu Rev Cell Dev Biol 14 (1998), 59-88.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 139
    • 0032718311 scopus 로고    scopus 로고
    • Hepatocellular carcinoma expressing both hepatocellular and biliary markers also expresses cytokeratin 14, a marker of bipotential progenitor cells
    • P.C. Wu et al., Hepatocellular carcinoma expressing both hepatocellular and biliary markers also expresses cytokeratin 14, a marker of bipotential progenitor cells, J Hepatol 31(5) (1999), 965-966.
    • (1999) J Hepatol , vol.31 , Issue.5 , pp. 965-966
    • Wu, P.C.1
  • 140
    • 0033606964 scopus 로고    scopus 로고
    • Smad2 and Smad4 gene mutations in hepatocellular carcinoma
    • M.C. Yakicier et al., Smad2 and Smad4 gene mutations in hepatocellular carcinoma, Oncogene 18(34) (1999), 4879-4883.
    • (1999) Oncogene , vol.18 , Issue.34 , pp. 4879-4883
    • Yakicier, M.C.1
  • 141
    • 0032973894 scopus 로고    scopus 로고
    • A molecular case report
    • DNA mismatch repair deficiency in curatively resected sextuple primary cancers in different organs
    • H. Yakushiji et al., DNA mismatch repair deficiency in curatively resected sextuple primary cancers in different organs: A molecular case report, Cancer Lett 142(1) (1999), 17-22.
    • (1999) Cancer Lett , vol.142 , Issue.1 , pp. 17-22
    • Yakushiji, H.1
  • 142
    • 0031028140 scopus 로고    scopus 로고
    • initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type I tumor necrosis factor receptor
    • Y. Yamada et al., initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor, Proc Natl Acad Sci USA 94(4) (1997), 1441-1446.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.4 , pp. 1441-1446
    • Yamada, Y.1
  • 143
    • 18544400776 scopus 로고    scopus 로고
    • Infrequent widespread microsatellite instability in hepatocellular carcinomas
    • H. Yamamoto et al., Infrequent widespread microsatellite instability in hepatocellular carcinomas, Int J Oncol 16(3) (2000), 543-547.
    • (2000) Int J Oncol , vol.16 , Issue.3 , pp. 543-547
    • Yamamoto, H.1
  • 144
    • 14944353116 scopus 로고    scopus 로고
    • HDPRI, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: Involvement of methylation-mediated gene silencing
    • T.O. Yau et al., HDPRI, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing, Oncogene 24 9) (2005), 1607-1614.
    • (2005) Oncogene , vol.24 , Issue.9 , pp. 1607-1614
    • Yau, T.O.1
  • 145
    • 1842587622 scopus 로고    scopus 로고
    • Expression of transforming growth factor-alpha and hepatitis B surface antigen in human hepatocellular carcinoma tissues and its significance
    • J. Zhang et al., Expression of transforming growth factor-alpha and hepatitis B surface antigen in human hepatocellular carcinoma tissues and its significance, World J Gastroenterol 10(6) (2004), 830-833.
    • (2004) World J Gastroenterol , vol.10 , Issue.6 , pp. 830-833
    • Zhang, J.1


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