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Volumn 145, Issue 8, 2004, Pages 3563-3565

β-cell lipotoxicity: Burning fat into heat?

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL; UNCOUPLING PROTEIN 2;

EID: 3843090515     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-0479     Document Type: Short Survey
Times cited : (20)

References (30)
  • 1
    • 0345374579 scopus 로고    scopus 로고
    • Minireview: Weapons of lean body mass destruction: The role of ectopic lipids in the metabolic syndrome
    • Unger RH 2003 Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome. Endocrinology 144:5159-5165
    • (2003) Endocrinology , vol.144 , pp. 5159-5165
    • Unger, R.H.1
  • 2
    • 0036153256 scopus 로고    scopus 로고
    • Minireview: Secondary β-cell failure in type 2 diabetes - A convergence of glucotoxicity and lipotoxicity
    • Poitout V, Robertson RP 2002 Minireview: secondary β-cell failure in type 2 diabetes - a convergence of glucotoxicity and lipotoxicity. Endocrinology 143: 339-242
    • (2002) Endocrinology , vol.143 , pp. 339-1242
    • Poitout, V.1    Robertson, R.P.2
  • 3
    • 0028817815 scopus 로고
    • U. K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: A progressive disease
    • U. K. Prospective Diabetes Study Group
    • 1995 U. K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U. K. Prospective Diabetes Study Group. Diabetes 44:1249-1258
    • (1995) Diabetes , vol.44 , pp. 1249-1258
  • 4
    • 0032898667 scopus 로고    scopus 로고
    • Fatty acids, lipotoxicity and insulin secretion
    • McGarry JD, Dobbins RL 1999 Fatty acids, lipotoxicity and insulin secretion. Diabetologia 42:128-138
    • (1999) Diabetologia , vol.42 , pp. 128-138
    • McGarry, J.D.1    Dobbins, R.L.2
  • 5
    • 3843145012 scopus 로고    scopus 로고
    • Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a β-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c
    • Yamashita T, Eto K, Okazaki Y, Yamashita S, Yamauchi T, Sekine N, Nagai R, Noda M, Kadowaki T 2004 Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a β-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c. Endocrinology 145:3566-3577
    • (2004) Endocrinology , vol.145 , pp. 3566-3577
    • Yamashita, T.1    Eto, K.2    Okazaki, Y.3    Yamashita, S.4    Yamauchi, T.5    Sekine, N.6    Nagai, R.7    Noda, M.8    Kadowaki, T.9
  • 6
    • 0031239663 scopus 로고    scopus 로고
    • How obesity causes diabetes in Zucker diabetic fatty rats
    • Unger RH 1997 How obesity causes diabetes in Zucker diabetic fatty rats. Trends Endocrinol Metab 8:276-282
    • (1997) Trends Endocrinol Metab , vol.8 , pp. 276-282
    • Unger, R.H.1
  • 7
    • 0035145780 scopus 로고    scopus 로고
    • Lipotoxicity of the pancreatic β-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids
    • Briaud I, Harmon JS, Kelpe CL, Segu VB, Poitout V 2001 Lipotoxicity of the pancreatic β-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids. Diabetes 50:315-321
    • (2001) Diabetes , vol.50 , pp. 315-321
    • Briaud, I.1    Harmon, J.S.2    Kelpe, C.L.3    Segu, V.B.4    Poitout, V.5
  • 8
    • 0029932643 scopus 로고    scopus 로고
    • New insights into pancreatic β-cell metabolic signaling in insulin secretion
    • Prentki M 1996 New insights into pancreatic β-cell metabolic signaling in insulin secretion. Eur J Endocrinol 134:272-286
    • (1996) Eur J Endocrinol , vol.134 , pp. 272-286
    • Prentki, M.1
  • 10
    • 3843061592 scopus 로고    scopus 로고
    • AMP kinase and malonyl-CoA: Targets for therapy of the metabolic syndrome
    • Ruderman N, Prentki M 2004 AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. Nat Rev Drug Discov 3:340-351
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 340-351
    • Ruderman, N.1    Prentki, M.2
  • 11
    • 0344081177 scopus 로고    scopus 로고
    • Minireview: The AMP-activated protein kinase cascade: The key sensor of cellular energy status
    • Hardie DG 2003 Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology 144:5179-5183
    • (2003) Endocrinology , vol.144 , pp. 5179-5183
    • Hardie, D.G.1
  • 12
    • 0032213768 scopus 로고    scopus 로고
    • AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic β-cells, and may regulate insulin release
    • Salt IP, Johnson G, Ashcroft SJ, Hardie DG 1998 AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic β-cells, and may regulate insulin release. Biochem J 335:533-539
    • (1998) Biochem J , vol.335 , pp. 533-539
    • Salt, I.P.1    Johnson, G.2    Ashcroft, S.J.3    Hardie, D.G.4
  • 13
    • 0036711553 scopus 로고    scopus 로고
    • New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: A role for the transcription factor sterol regulatory element binding protein-1c
    • Foufelle F, Ferre P 2002 New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c. Biochem J 366:377-391
    • (2002) Biochem J , vol.366 , pp. 377-391
    • Foufelle, F.1    Ferre, P.2
  • 16
    • 1642546212 scopus 로고    scopus 로고
    • Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: Modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)
    • Diraison F, Parton L, Ferre P, Foufelle F, Briscoe CP, Leclerc I, Rutter GA 2004 Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR). Biochem J 378:769-778
    • (2004) Biochem J , vol.378 , pp. 769-778
    • Diraison, F.1    Parton, L.2    Ferre, P.3    Foufelle, F.4    Briscoe, C.P.5    Leclerc, I.6    Rutter, G.A.7
  • 19
    • 0032991716 scopus 로고    scopus 로고
    • Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets
    • Chan CB, MacDonald PE, Saleh MC, Johns DC, Marban E, Wheeler MB 1999 Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets. Diabetes 48:1482-1486
    • (1999) Diabetes , vol.48 , pp. 1482-1486
    • Chan, C.B.1    MacDonald, P.E.2    Saleh, M.C.3    Johns, D.C.4    Marban, E.5    Wheeler, M.B.6
  • 22
    • 0036829870 scopus 로고    scopus 로고
    • Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet
    • Joseph JW, Koshkin V, Zhang CY, Wang J, Lowell BB, Chan CB, Wheeler MB 2002 Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet. Diabetes 51:3211-3219
    • (2002) Diabetes , vol.51 , pp. 3211-3219
    • Joseph, J.W.1    Koshkin, V.2    Zhang, C.Y.3    Wang, J.4    Lowell, B.B.5    Chan, C.B.6    Wheeler, M.B.7
  • 23
    • 0036318123 scopus 로고    scopus 로고
    • Differential effects of hyperlipidemia on insulin secretion in islets of Langerhans from hyperglycemic vs. normoglycemic rats
    • Briaud I, Kelpe CL, Johnson LM, Tran POT, Poitout V 2002 Differential effects of hyperlipidemia on insulin secretion in islets of Langerhans from hyperglycemic vs. normoglycemic rats. Diabetes 51:662-668
    • (2002) Diabetes , vol.51 , pp. 662-668
    • Briaud, I.1    Kelpe, C.L.2    Johnson, L.M.3    Tran, P.O.T.4    Poitout, V.5
  • 24
    • 0035078830 scopus 로고    scopus 로고
    • Uncoupling protein 2: A possible link between fatty acid excess and impaired glucose-induced insulin secretion?
    • Lameloise N, Muzzin P, Prentki M, Assimacopoulos-Jeannet F 2001 Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion? Diabetes 50:803-809
    • (2001) Diabetes , vol.50 , pp. 803-809
    • Lameloise, N.1    Muzzin, P.2    Prentki, M.3    Assimacopoulos-Jeannet, F.4
  • 25
    • 0036724133 scopus 로고    scopus 로고
    • Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-γ inhibition
    • Patanè G, Anello M, Piro S, Vigneri R, Purrello F, Rabuazzo AM 2002 Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-γ inhibition. Diabetes 51: 2749-2756
    • (2002) Diabetes , vol.51 , pp. 2749-2756
    • Patanè, G.1    Anello, M.2    Piro, S.3    Vigneri, R.4    Purrello, F.5    Rabuazzo, A.M.6
  • 27
    • 0035815650 scopus 로고    scopus 로고
    • Transcriptional regulation of the mouse uncoupling protein-2 gene. Double E-box motif is required for peroxisome proliferator-activated receptor-γ-dependent activation
    • Medvedev AV, Snedden SK, Raimbault S, Ricquier D, Collins S 2001 Transcriptional regulation of the mouse uncoupling protein-2 gene. Double E-box motif is required for peroxisome proliferator-activated receptor-γ- dependent activation. J Biol Chem 276:10817-10823
    • (2001) J Biol Chem , vol.276 , pp. 10817-10823
    • Medvedev, A.V.1    Snedden, S.K.2    Raimbault, S.3    Ricquier, D.4    Collins, S.5
  • 28
    • 0035489034 scopus 로고    scopus 로고
    • The expression of hormone-sensitive lipase in clonal β-cells and rat islets is induced by long-term exposure to high glucose
    • Winzell MS, Svensson H, Arner P, Ahren B, Holm C 2001 The expression of hormone-sensitive lipase in clonal β-cells and rat islets is induced by long-term exposure to high glucose. Diabetes 50:2225-2230
    • (2001) Diabetes , vol.50 , pp. 2225-2230
    • Winzell, M.S.1    Svensson, H.2    Arner, P.3    Ahren, B.4    Holm, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.