-
1
-
-
0003775053
-
Heart Disease and Stroke Statistics - 2003 Update
-
Heart Disease and Stroke Statistics - 2003 Update. (2002).
-
(2002)
-
-
-
2
-
-
0032842144
-
Direct myocardial revascularization and angiogenesis - How many patients might be eligible?
-
(A8)
-
MUKHERJEE D, BHATT DL, ROE MT, PATEL V, ELLIS SG: Direct myocardial revascularization and angiogenesis - how many patients might be eligible? Am. J. Cardiol. (1999) 94:598-600 (A8).
-
(1999)
Am. J. Cardiol.
, vol.94
, pp. 598-600
-
-
Mukherjee, D.1
Bhatt, D.L.2
Roe, M.T.3
Patel, V.4
Ellis, S.G.5
-
3
-
-
0242660995
-
Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF-2)
-
AVILES RJ, ANNEX BH, LEDERMAN RJ: Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF-2). Br. J. Pharmacol. (2003) 140:637-646.
-
(2003)
Br. J. Pharmacol.
, vol.140
, pp. 637-646
-
-
Aviles, R.J.1
Annex, B.H.2
Lederman, R.J.3
-
4
-
-
0034234393
-
Isolated bypass grafting of the left internal thoracic artery to the left anterior descending coronary artery: Late consequences of incomplete revascularization
-
SCOTT R, BLACKSTONE EH, McCARTHY PM et al.: Isolated bypass grafting of the left internal thoracic artery to the left anterior descending coronary artery. late consequences of incomplete revascularization. J. Thorac. Cardiovasc. Surg. (2000) 120:173-184.
-
(2000)
J. Thorac. Cardiovasc. Surg.
, vol.120
, pp. 173-184
-
-
Scott, R.1
Blackstone, E.H.2
McCarthy, P.M.3
-
5
-
-
0029958320
-
Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo
-
TAKESHITA S, TSURUMI Y, COUFFINAHL T et al.: Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo. Lab. Invest. (1996) 75:487-501.
-
(1996)
Lab. Invest.
, vol.75
, pp. 487-501
-
-
Takeshita, S.1
Tsurumi, Y.2
Couffinahl, T.3
-
6
-
-
0343632352
-
Treatment of acute limb ischemia by intramuscular injection of vascular endothelial growth factor gene
-
TSURUMI Y, KEARNEY M, CHEN D et al.: Treatment of acute limb ischemia by intramuscular injection of vascular endothelial growth factor gene. Circulation (1997) 96:II-382-388.
-
(1997)
Circulation
, vol.96
-
-
Tsurumi, Y.1
Kearney, M.2
Chen, D.3
-
7
-
-
0035818612
-
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic hind limb ischemia model: Molecular mechanisms of delayed angiogenesis in diabetes
-
TANIYAMA Y, MORISHITA R, HIRAOKA K et al.: Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic hind limb ischemia model: molecular mechanisms of delayed angiogenesis in diabetes. Circulation (2001) 104:2344-2350.
-
(2001)
Circulation
, vol.104
, pp. 2344-2350
-
-
Taniyama, Y.1
Morishita, R.2
Hiraoka, K.3
-
8
-
-
0037265253
-
Fibroblast growth factor 4 induces vascular permeability, angiogenesis and arteriogenesis in a rabbit hindlimb ischemia model
-
RISSANEN TT, MARKKANEN JE, ARVE K et al.: Fibroblast growth factor 4 induces vascular permeability, angiogenesis and arteriogenesis in a rabbit hindlimb ischemia model. Faseb J. (2003) 17:100-102.
-
(2003)
Faseb. J.
, vol.17
, pp. 100-102
-
-
Rissanen, T.T.1
Markkanen, J.E.2
Arve, K.3
-
9
-
-
0036341231
-
Human endothelial nitric oxide synthase gene delivery promotes angiogenesis in a rat model of hindlimb ischemia
-
SMITH RS Jr, LIN KF, AGATA J, CHAO L, CHAO J: Human endothelial nitric oxide synthase gene delivery promotes angiogenesis in a rat model of hindlimb ischemia. Arterioscler. Thromb. Vasc. Biol. (2002) 22:1279-1285.
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 1279-1285
-
-
Smith Jr., R.S.1
Lin, K.F.2
Agata, J.3
Chao, L.4
Chao, J.5
-
10
-
-
0242361643
-
Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model
-
NAMBA T, KOIKE H, MURAKAMI K et al.: Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model. Circulation (2003) 108:2250-2257.
-
(2003)
Circulation
, vol.108
, pp. 2250-2257
-
-
Namba, T.1
Koike, H.2
Murakami, K.3
-
11
-
-
17744388788
-
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: Preclinical study for treatment of peripheral arterial disease
-
TANIYAMA Y, MORISHITA R, AOKI M et al.: Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease. Gene Ther. (2001) 8:181-189.
-
(2001)
Gene Ther.
, vol.8
, pp. 181-189
-
-
Taniyama, Y.1
Morishita, R.2
Aoki, M.3
-
12
-
-
0033971692
-
Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothetial growth factor 121
-
(Discussion 23-24)
-
LEE LY, PATEL SR, HACKETT NR et al.: Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothetial growth factor 121. Ann. Thorac. Surg. (2000) 69:14-23 (Discussion 23-24).
-
(2000)
Ann. Thorac. Surg.
, vol.69
, pp. 14-23
-
-
Lee, L.Y.1
Patel, S.R.2
Hackett, N.R.3
-
13
-
-
0029877965
-
Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart
-
GIORDANO FJ, PING P, McKIRNAN MD et al.: Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart. Nat. Med. (1996) 2:534-539.
-
(1996)
Nat. Med.
, vol.2
, pp. 534-539
-
-
Giordano, F.J.1
Ping, P.2
McKirnan, M.D.3
-
14
-
-
10744230276
-
Arteriogenesis induced by intramyocardial vascular endothelial growth factor 165 gene transfer in chronically ischemic pigs
-
CROTTOGINI A, MECKERT PC, VERA JANAVEL G et al.: Arteriogenesis induced by intramyocardial vascular endothelial growth factor 165 gene transfer in chronically ischemic pigs. Hum. Gene Ther. (2003) 14:1307-1318.
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 1307-1318
-
-
Crottogini, A.1
Meckert, P.C.2
Vera Janavel, G.3
-
15
-
-
0036622139
-
Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure
-
LEOTTA E, PATEJUNAS G, MURPHY G et al.: Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure. J. Thorac. Cardiovasc. Surg. (2002) 123:1101-1113.
-
(2002)
J. Thorac. Cardiovasc. Surg.
, vol.123
, pp. 1101-1113
-
-
Leotta, E.1
Patejunas, G.2
Murphy, G.3
-
16
-
-
0242459072
-
Angiogenic gene therapy with adenovirus 5 fibroblast growth factor-4 (Ad5FGF-4): A new option for the treatment of coronary artery disease
-
GRINES C, RUBANYI GM, KLEIMAN NS, MARROTT P, WATKINS MW: Angiogenic gene therapy with adenovirus 5 fibroblast growth factor-4 (Ad5FGF-4): a new option for the treatment of coronary artery disease. Am. J. Cardiol. (2003) 92:24N-31N.
-
(2003)
Am. J. Cardiol.
, vol.92
-
-
Grines, C.1
Rubanyi, G.M.2
Kleiman, N.S.3
Marrott, P.4
Watkins, M.W.5
-
18
-
-
0242606216
-
Therapeutic angiogenesis in cardiovascular disease
-
SIMONS M, WARE JA: Therapeutic angiogenesis in cardiovascular disease. Nat. Rev. Drug Discov. (2003) 2:863-871.
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 863-871
-
-
Simons, M.1
Ware, J.A.2
-
19
-
-
0142023866
-
Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: A Phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication
-
RAJAGOPALAN S, MOHLER ER 3rd, LEDERMAN RJ et al.: Regional angiogenesis with vascular endothelial growth factor in peripheral arterial disease: a Phase II randomized, double-blind, controlled study of adenoviral delivery of vascular endothelial growth factor 121 in patients with disabling intermittent claudication. Circulation (2003) 108:1933-1938.
-
(2003)
Circulation
, vol.108
, pp. 1933-1938
-
-
Rajagopalan, S.1
Mohler III, E.R.2
Lederman, R.J.3
-
20
-
-
0038210219
-
Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and instent restenosis and in the treatment of chronic myocardial ischemia: Phase II results of the Kuopio Angiogenesis Trial (KAT)
-
HEDMAN M, HARTIKAINEN J, SYVANNE M et al.: Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and instent restenosis and in the treatment of chronic myocardial ischemia: Phase II results of the Kuopio Angiogenesis Trial (KAT). Circulation (2003) 107:2677-2683.
-
(2003)
Circulation
, vol.107
, pp. 2677-2683
-
-
Hedman, M.1
Hartikainen, J.2
Syvanne, M.3
-
21
-
-
0142107372
-
A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina
-
GRINES CL, WATKINS MW, MAHMARIAN JJ et al.: A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina. J. Am. Coll. Cardiol. (2003) 42:1339-1347.
-
(2003)
J. Am. Coll. Cardiol.
, vol.42
, pp. 1339-1347
-
-
Grines, C.L.1
Watkins, M.W.2
Mahmarian, J.J.3
-
22
-
-
0036665610
-
Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: A randomized, placebo-controlled, double-blinded Phase II study
-
MAKINEN K, MANNINEN H, HEDMAN M et al.: Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded Phase II study. Mol. Ther. (2002) 6:127-133.
-
(2002)
Mol. Ther.
, vol.6
, pp. 127-133
-
-
Makinen, K.1
Manninen, H.2
Hedman, M.3
-
23
-
-
0037453099
-
The VIVA trial: Vascular endothelial growth factor in ischemia for vascular angiogenesis
-
HENRY TD, ANNEX BH, McKENDALL GR et al.: The VIVA trial: vascular endothelial growth factor in ischemia for vascular angiogenesis. Circulation (2003) 107:1359-1365.
-
(2003)
Circulation
, vol.107
, pp. 1359-1365
-
-
Henry, T.D.1
Annex, B.H.2
McKendall, G.R.3
-
24
-
-
0037097035
-
Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): A randomised trial
-
LEDERMAN RJ, MENDELSOHN FO, ANDERSON RD et al.: Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial. Lancet (2002) 359:2053-2058.
-
(2002)
Lancet
, vol.359
, pp. 2053-2058
-
-
Lederman, R.J.1
Mendelsohn, F.O.2
Anderson, R.D.3
-
25
-
-
0037133306
-
Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: Double-blind, randomized, controlled clinical trial
-
SIMONS M, ANNEX BH, LAHAM RJ et al.: Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: double-blind, randomized, controlled clinical trial. Circulation (2002) 105:788-793.
-
(2002)
Circulation
, vol.105
, pp. 788-793
-
-
Simons, M.1
Annex, B.H.2
Laham, R.J.3
-
26
-
-
0033517733
-
Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: Results of a Phase I randomized, double-blind, placebo-controlled trial
-
LAHAM RJ, SELLKE FW, EDELMAN ER et al.: Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a Phase I randomized, double-blind, placebo-controlled trial. Circulation (1999) 100:1865-1871.
-
(1999)
Circulation
, vol.100
, pp. 1865-1871
-
-
Laham, R.J.1
Sellke, F.W.2
Edelman, E.R.3
-
27
-
-
0036658287
-
Long-term effects of surgical angiogenic therapy with fibroblast growth factor 2 protein
-
RUEL M, LAHAM RJ, PARKER JA et al.: Long-term effects of surgical angiogenic therapy with fibroblast growth factor 2 protein. J. Thorac. Cardiovasc. Surg. (2002) 124:28-34.
-
(2002)
J. Thorac. Cardiovasc. Surg.
, vol.124
, pp. 28-34
-
-
Ruel, M.1
Laham, R.J.2
Parker, J.A.3
-
29
-
-
0034687141
-
Angiogenesis is impaired by hypercholesterolemia: Role of asymmetric dimethylarginine
-
JANG JJ, HO HK, KWAN HH, FAJARDO LF, COOKE JP: Angiogenesis is impaired by hypercholesterolemia: role of asymmetric dimethylarginine. Circulation (2000) 102:1414-1419.
-
(2000)
Circulation
, vol.102
, pp. 1414-1419
-
-
Jang, J.J.1
Ho, H.K.2
Kwan, H.H.3
Fajardo, L.F.4
Cooke, J.P.5
-
30
-
-
0034619383
-
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: Nitric oxide-dependent mechanism
-
DUAN J, MUROHARA T, IKEDA H et al.: Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism. Circulation (2000) 102:III370-376.
-
(2000)
Circulation
, vol.102
-
-
Duan, J.1
Murohara, T.2
Ikeda, H.3
-
31
-
-
0037811929
-
Rescue of hypercholesterolemia-related impairment of angiogenesis by oral folate supplementation
-
SASAKI K, DUAN J, MUROHARA T et al.: Rescue of hypercholesterolemia-related impairment of angiogenesis by oral folate supplementation. J. Am. Coll. Cardiol. (2003) 42:364-372.
-
(2003)
J. Am. Coll. Cardiol.
, vol.42
, pp. 364-372
-
-
Sasaki, K.1
Duan, J.2
Murohara, T.3
-
32
-
-
0030853575
-
Hypercholesterolemia attenuates angiogenesis but does not preclude augmentation by angiogenic cytokines
-
VAN BELLE E, RIVARD A, CHEN D et al.: Hypercholesterolemia attenuates angiogenesis but does not preclude augmentation by angiogenic cytokines. Circulation (1997) 96:2667-2674.
-
(1997)
Circulation
, vol.96
, pp. 2667-2674
-
-
Van Belle, E.1
Rivard, A.2
Chen, D.3
-
33
-
-
0038380432
-
Inhibition of hypoxia-induced angiogenesis by cigarette smoke exposure: Impairment of the HIF-1α/VEGF pathway
-
MICHAUD SE, MENARD C, GUY LG, GENNARO G, RIVARD A: Inhibition of hypoxia-induced angiogenesis by cigarette smoke exposure: impairment of the HIF-1α/VEGF pathway. Faseb J. (2003) 17:1150-1152.
-
(2003)
Faseb. J.
, vol.17
, pp. 1150-1152
-
-
Michaud, S.E.1
Menard, C.2
Guy, L.G.3
Gennaro, G.4
Rivard, A.5
-
34
-
-
0042917704
-
Inhibition of the cardiac angiogenic response to surgical FGF-2 therapy in a Swine endothelial dysfunction model
-
RUEL M, WU GF, KHAN TA et al.: Inhibition of the cardiac angiogenic response to surgical FGF-2 therapy in a Swine endothelial dysfunction model. Circulation (2003) 108(Suppl. 1):II335-II340.
-
(2003)
Circulation
, vol.108
, Issue.SUPPL. 1
-
-
Ruel, M.1
Wu, G.F.2
Khan, T.A.3
-
35
-
-
0037721109
-
Synergistic effect of angiopoietin-1 and vascular endothelial growth factor on neoangiogenesis in hypercholesterolemic rabbit model with acute hindlimb ischemia
-
SHYU KG, CHANG H, ISNER JM: Synergistic effect of angiopoietin-1 and vascular endothelial growth factor on neoangiogenesis in hypercholesterolemic rabbit model with acute hindlimb ischemia. Life Sci. (2003) 73:563-579.
-
(2003)
Life Sci.
, vol.73
, pp. 563-579
-
-
Shyu, K.G.1
Chang, H.2
Isner, J.M.3
-
37
-
-
0028827625
-
Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
-
ASAHARA T, BAUTERS C, ZHENG LP et al.: Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. Circulation (1995) 92:II365-371.
-
(1995)
Circulation
, vol.92
-
-
Asahara, T.1
Bauters, C.2
Zheng, L.P.3
-
38
-
-
0033664632
-
Coadministration of angiopoietin-1 and vascular endothelial growth factor enhances collateral vascularization
-
CHAE JK, KIM I, LIM ST et al.: Coadministration of angiopoietin-1 and vascular endothelial growth factor enhances collateral vascularization. Arterioscler. Thromb. Vasc. Biol. (2000) 20:2573-2578.
-
(2000)
Arterioscler. Thromb. Vasc. Biol.
, vol.20
, pp. 2573-2578
-
-
Chae, J.K.1
Kim, I.2
Lim, S.T.3
-
39
-
-
0037297359
-
Gene therapy progress and prospects: Therapeutic angiogenesis for limb and myocardial ischemia
-
KHAN TA, SELLKE FW, LAHAM RJ: Gene therapy progress and prospects: therapeutic angiogenesis for limb and myocardial ischemia. Gene Ther. (2003) 10:285-291.
-
(2003)
Gene Ther.
, vol.10
, pp. 285-291
-
-
Khan, T.A.1
Sellke, F.W.2
Laham, R.J.3
-
40
-
-
0034641624
-
Clinical trials in coronary angiogenesis: Issues, problems, consensus: An expert panel summary
-
SIMONS M, BONOW RO, CHRONOS NA et al.: Clinical trials in coronary angiogenesis: issues, problems, consensus: An expert panel summary. Circulation (2000) 102:E73-E86.
-
(2000)
Circulation
, vol.102
-
-
Simons, M.1
Bonow, R.O.2
Chronos, N.A.3
-
41
-
-
0038376002
-
Molecular regulation of vessel maturation
-
JAIN RK: Molecular regulation of vessel maturation. Nat. Med. (2003) 9:685-693.
-
(2003)
Nat. Med.
, vol.9
, pp. 685-693
-
-
Jain, R.K.1
-
42
-
-
0037699955
-
Angiogenesis in health and disease
-
CARMELIET P: Angiogenesis in health and disease. Nat. Med. (2003) 9:653-660.
-
(2003)
Nat. Med.
, vol.9
, pp. 653-660
-
-
Carmeliet, P.1
-
43
-
-
0032881898
-
Role of vascular endothelial growth factor in the regulation of angiogenesis
-
FERRARA N: Role of vascular endothelial growth factor in the regulation of angiogenesis. Kidney Int. (1999) 56:794-814.
-
(1999)
Kidney Int.
, vol.56
, pp. 794-814
-
-
Ferrara, N.1
-
44
-
-
0025999033
-
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
-
TISCHER E, MITCHELL R, HARTMAN T et al.: The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J. Biol. Chem. (1991) 266:11947-11954.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11947-11954
-
-
Tischer, E.1
Mitchell, R.2
Hartman, T.3
-
45
-
-
0030614869
-
VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix
-
POLTORAK Z, COHEN T, SIVAN R et al.: VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix. J. Biol. Chem. (1997) 272:7151-7158.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7151-7158
-
-
Poltorak, Z.1
Cohen, T.2
Sivan, R.3
-
46
-
-
0038269097
-
VEGF162, a new heparin-binding vascular endothelial growth factor splice form that is expressed in transformed human cells
-
LANGE T, GUTTMANN-RAVIV N, BARUCH L, MACHLUF M, NEUFELD G: VEGF162, a new heparin-binding vascular endothelial growth factor splice form that is expressed in transformed human cells. J. Biol. Chem. (2003) 278:17164-17169.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17164-17169
-
-
Lange, T.1
Guttmann-Raviv, N.2
Baruch, L.3
Machluf, M.4
Neufeld, G.5
-
47
-
-
0030054913
-
Similarities and differences between the vascular endothelial growth factor (VEGF) splice variants
-
NEUFELD G, COHEN T, GITAY-GOREN H et al.: Similarities and differences between the vascular endothelial growth factor (VEGF) splice variants. Cancer Metastasis Rev. (1996) 15:153-158.
-
(1996)
Cancer Metastasis Rev.
, vol.15
, pp. 153-158
-
-
Neufeld, G.1
Cohen, T.2
Gitay-Goren, H.3
-
48
-
-
0033830523
-
Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature
-
GRUNSTEIN J, MASBAD JJ, HICKEY R, GIORDANO F, JOHNSON RS: Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature. Mol. Cell Biol. (2000) 20:7282-7291.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 7282-7291
-
-
Grunstein, J.1
Masbad, J.J.2
Hickey, R.3
Giordano, F.4
Johnson, R.S.5
-
49
-
-
1142299565
-
Adenovirus-mediated transfer of a minigene expressing multiple isoforms of VEGF is more effective at inducing angiogenesis than comparable vectors expressing individual VEGF cDNAs
-
WHITLOCK PR, HACKETT NR, LEOPOLD PL, ROSENGART TK, CRYSTAL RG: Adenovirus-mediated transfer of a minigene expressing multiple isoforms of VEGF is more effective at inducing angiogenesis than comparable vectors expressing individual VEGF cDNAs. Mol. Ther. (2004) 9:67-75.
-
(2004)
Mol. Ther.
, vol.9
, pp. 67-75
-
-
Whitlock, P.R.1
Hackett, N.R.2
Leopold, P.L.3
Rosengart, T.K.4
Crystal, R.G.5
-
50
-
-
3843103708
-
Transcriptional activation of the endogenous VEGF gene by small molecule regulated engineered transcription factors
-
Washington DC, USA (Abstract 786)
-
DENT CL, LAU G, LIANG Y, CASE CC, PABO CO: Transcriptional activation of the endogenous VEGF gene by small molecule regulated engineered transcription factors. American Society of Gene Therapy.. Washington DC, USA (2003) (Abstract 786).
-
(2003)
American Society of Gene Therapy
-
-
Dent, C.L.1
Lau, G.2
Liang, Y.3
Case, C.C.4
Pabo, C.O.5
-
51
-
-
0033542389
-
Ligand-dependent regulation of plasmid-based transgene expression in vivo
-
ABRUZZESE RV, GODIN D, BURCIN M et al.: Ligand-dependent regulation of plasmid-based transgene expression in vivo. Hum. Gene Ther. (1999) 10:1499-1507.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1499-1507
-
-
Abruzzese, R.V.1
Godin, D.2
Burcin, M.3
-
52
-
-
0035989652
-
Regulation of endogenous gene expression with a small-molecule dimerizer
-
POLLOCK R, GIEL M, LINHER K, CLACKSON T: Regulation of endogenous gene expression with a small-molecule dimerizer. Nat. Biotechnol. (2002) 20:729-733.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 729-733
-
-
Pollock, R.1
Giel, M.2
Linher, K.3
Clackson, T.4
-
53
-
-
0025825895
-
Modular structure of transcription factors: Implications for gene regulation
-
FRANKEL AD, KIM PS: Modular structure of transcription factors: implications for gene regulation. Cell (1991) 65:717-719.
-
(1991)
Cell
, vol.65
, pp. 717-719
-
-
Frankel, A.D.1
Kim, P.S.2
-
54
-
-
0035709610
-
Tissue-specific expression of an anti-proliferative hybrid transgene from the human smooth muscle α-actin promoter suppresses smooth muscle cell proliferation and neointima formation
-
WILLS KN, MANO T, AVANZINI JB et al.: Tissue-specific expression of an anti-proliferative hybrid transgene from the human smooth muscle α-actin promoter suppresses smooth muscle cell proliferation and neointima formation. Gene Ther. (2001) 8:1847-1854.
-
(2001)
Gene Ther.
, vol.8
, pp. 1847-1854
-
-
Wills, K.N.1
Mano, T.2
Avanzini, J.B.3
-
55
-
-
0037459007
-
Conditional expression of a dominant-negative c-Myb in vascular smooth muscle cells inhibits arterial remodeling after injury
-
YOU XM, MUNGRUE IN, KALAIR W et al.: Conditional expression of a dominant-negative c-Myb in vascular smooth muscle cells inhibits arterial remodeling after injury. Circ. Res. (2003) 92:314-321.
-
(2003)
Circ. Res.
, vol.92
, pp. 314-321
-
-
You, X.M.1
Mungrue, I.N.2
Kalair, W.3
-
56
-
-
0033233243
-
2 homeostasis by hypoxia-inducible factor 1
-
2 homeostasis by hypoxia-inducible factor 1. Ann. Rev. Cell. Dev. Biol. (1999) 15:551-578.
-
(1999)
Ann. Rev. Cell. Dev. Biol.
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
59
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
BRUICK RK, McKNIGHT SL: A conserved family of prolyl-4-hydroxylases that modify HIF. Science (2001) 294:1337-1340.
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
60
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
EPSTEIN AC, GLEADLE JM, McNEILL LA et al.: C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell (2001) 107:43-54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.1
Gleadle, J.M.2
McNeill, L.A.3
-
61
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch
-
LANDO D, PEET DJ, WHELAN DA, GORMAN JJ, WHITELAW ML: Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science (2002) 295:858-861.
-
(2002)
Science
, vol.295
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
62
-
-
0034739533
-
Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1α/VP16 hybrid transcription factor
-
VINCENT KA, SHYU KG, LUO Y et al.: Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1α /VP16 hybrid transcription factor. Circulation (2000) 102:2255-2261.
-
(2000)
Circulation
, vol.102
, pp. 2255-2261
-
-
Vincent, K.A.1
Shyu, K.G.2
Luo, Y.3
-
63
-
-
0344874751
-
Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1
-
KELLY BD, HACKETT SF, HIROTA K et al.: Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1. Circ. Res. (2003) 93:1074-1081.
-
(2003)
Circ. Res.
, vol.93
, pp. 1074-1081
-
-
Kelly, B.D.1
Hackett, S.F.2
Hirota, K.3
-
64
-
-
0023697252
-
GAL4-VP16 is an unusually potent transcriptional activator
-
SADOWSKI I, MA J, TRIEZENBERG S, PTASHNE M: GAL4-VP16 is an unusually potent transcriptional activator. Nature (1988) 335:563-564.
-
(1988)
Nature
, vol.335
, pp. 563-564
-
-
Sadowski, I.1
Ma, J.2
Triezenberg, S.3
Ptashne, M.4
-
65
-
-
0024024137
-
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression
-
TRIEZENBERG SJ, KINGSBURY RC, MCKNIGHT SL: Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. Genes Dev. (1988) 2:718-729.
-
(1988)
Genes Dev.
, vol.2
, pp. 718-729
-
-
Triezenberg, S.J.1
Kingsbury, R.C.2
Mcknight, S.L.3
-
66
-
-
18444364209
-
Stabilization of vascular endothelial growth factor mRNA by hypoxia-inducible factor 1
-
LIU LX, LU H, LUO Y et al.: Stabilization of vascular endothelial growth factor mRNA by hypoxia-inducible factor 1. Biochem. Biophys. Res. Commun. (2002) 291:908-914.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.291
, pp. 908-914
-
-
Liu, L.X.1
Lu, H.2
Luo, Y.3
-
67
-
-
0036660804
-
Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: Role of hypoxia inducible factor 1alpha
-
BELANGER AJ, LU H, DATE T et al.: Hypoxia up-regulates expression of peroxisome proliferator-activated receptor gamma angiopoietin-related gene (PGAR) in cardiomyocytes: role of hypoxia inducible factor 1alpha. J. Mol. Cell. Cardiol. (2002) 34:765-774.
-
(2002)
J. Mol. Cell. Cardiol.
, vol.34
, pp. 765-774
-
-
Belanger, A.J.1
Lu, H.2
Date, T.3
-
68
-
-
0141640863
-
Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors
-
YAMAKAWA M, LIU LX, DATE T et al.: Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors. Circ. Res. (2003) 93:664-673.
-
(2003)
Circ. Res.
, vol.93
, pp. 664-673
-
-
Yamakawa, M.1
Liu, L.X.2
Date, T.3
-
69
-
-
0037060621
-
Gene expression profiles in human cardiac cells subjected to hypoxia or expressing a hybrid form of HIF-1α
-
JLANG C, LU H, VINCENT KA et al.: Gene expression profiles in human cardiac cells subjected to hypoxia or expressing a hybrid form of HIF-1α. Physiol. Genomics (2002) 8:23-32.
-
(2002)
Physiol. Genomics
, vol.8
, pp. 23-32
-
-
Jlang, C.1
Lu, H.2
Vincent, K.A.3
-
70
-
-
0036275028
-
Intramyocardial injection of naked DNA encoding HIF-1α/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat
-
SHYU KG, WANG MT, WANG BW et al.: Intramyocardial injection of naked DNA encoding HIF-1α/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat. Cardiovasc. Res. (2002) 54:576-583.
-
(2002)
Cardiovasc. Res.
, vol.54
, pp. 576-583
-
-
Shyu, K.G.1
Wang, M.T.2
Wang, B.W.3
-
71
-
-
3843080756
-
Harnessing the response to hypoxia: Use of a constitutively active hypoxia-inducible factor 1-a transgene in no-option critical limb ischemia patients
-
American Heart Association Scientific Sessions. Orlando, USA (Abstract 2034)
-
RAJAGOPALAN S, DEITCHER S, OLIN J et al.: Harnessing the response to hypoxia: use of a constitutively active hypoxia-inducible factor 1-a transgene in no-option critical limb ischemia patients. American Heart Association Scientific Sessions. Orlando, USA (2003) (Abstract 2034).
-
(2003)
-
-
Rajagopalan, S.1
Deitcher, S.2
Olin, J.3
-
72
-
-
0040215628
-
Repetitive zinc-binding domains in the protein transcription Factor IIIA from Xenopus oocytes
-
MILLER J, McLACHLAN AD, KLUG A: Repetitive zinc-binding domains in the protein transcription Factor IIIA from Xenopus oocytes. EMBO J. (1985) 4:1609-1614.
-
(1985)
EMBO J.
, vol.4
, pp. 1609-1614
-
-
Miller, J.1
McLachlan, A.D.2
Klug, A.3
-
73
-
-
0022421362
-
The primary structure of transcription factor TFIIIA has 12 consecutive repeats
-
BROWN RS, SANDER C, ARGOS P: The primary structure of transcription factor TFIIIA has 12 consecutive repeats. FEBS Lett. (1985) 186:271-274.
-
(1985)
FEBS Lett.
, vol.186
, pp. 271-274
-
-
Brown, R.S.1
Sander, C.2
Argos, P.3
-
74
-
-
0034923498
-
Design and selection of novel Cys2His2 zinc finger proteins
-
PABO CO, PEISACH E, GRANT RA: Design and selection of novel Cys2His2 zinc finger proteins. Ann. Rev. Biochem. (2001) 70:313-340.
-
(2001)
Ann. Rev. Biochem.
, vol.70
, pp. 313-340
-
-
Pabo, C.O.1
Peisach, E.2
Grant, R.A.3
-
75
-
-
0000127073
-
Sequence-specific recognition of double helical nucleic acids by proteins
-
SEEMAN NC, ROSENBERG JM, RICH A: Sequence-specific recognition of double helical nucleic acids by proteins. Proc. Natl. Acad. Sci. USA (1976) 73:804-808.
-
(1976)
Proc. Natl. Acad. Sci. USA
, vol.73
, pp. 804-808
-
-
Seeman, N.C.1
Rosenberg, J.M.2
Rich, A.3
-
76
-
-
0024391088
-
DNA binding site of the growth factor-inducible protein Zif268
-
CHRISTY B, NATHANS D: DNA binding site of the growth factor-inducible protein Zif268. Proc. Natl. Acad. Sci. USA (1989) 86:8737-8741.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 8737-8741
-
-
Christy, B.1
Nathans, D.2
-
77
-
-
0025773296
-
Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1 A
-
PAVLETICH NP, PABO CO: Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A. Science (1991) 252:809-817.
-
(1991)
Science
, vol.252
, pp. 809-817
-
-
Pavletich, N.P.1
Pabo, C.O.2
-
78
-
-
0027401045
-
Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins
-
DESJARLAIS JR, BERG JM: Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins. Proc. Natl. Acad. Sci. USA (1993) 90:2256-2260.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2256-2260
-
-
Desjarlais, J.R.1
Berg, J.M.2
-
79
-
-
0037040240
-
Validated zinc finger protein designs for all 16 GNN DNA triplet rargets
-
LIU Q, XIA Z, ZHONG X, CASE CC: Validated zinc finger protein designs for all 16 GNN DNA triplet rargets. J. Biol. Chem. (2002) 277:3850-3856.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3850-3856
-
-
Liu, Q.1
Xia, Z.2
Zhong, X.3
Case, C.C.4
-
80
-
-
0037335514
-
Human zinc fingers as building blocks in the construction of artificial transcription factors
-
BAE KH, KWON YD, SHIN HC et al.: Human zinc fingers as building blocks in the construction of artificial transcription factors. Nat. Biotechnol. (2003) 21:275-280.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 275-280
-
-
Bae, K.H.1
Kwon, Y.D.2
Shin, H.C.3
-
81
-
-
0028328872
-
Zinc finger phage: Affinity selection of fingers with new DNA-binding specificities
-
REBAR EJ, PABO CO: Zinc finger phage: affinity selection of fingers with new DNA-binding specificities. Science (1994) 263:671-673.
-
(1994)
Science
, vol.263
, pp. 671-673
-
-
Rebar, E.J.1
Pabo, C.O.2
-
82
-
-
0029942895
-
Phage display methods for selecting zinc finger proteins with novel DNA- binding specificities
-
REBAR EJ, GREISMAN RA, PABO CO: Phage display methods for selecting zinc finger proteins with novel DNA- binding specificities. Methods Enzymol. (1996) 267:129-149.
-
(1996)
Methods Enzymol.
, vol.267
, pp. 129-149
-
-
Rebar, E.J.1
Greisman, R.A.2
Pabo, C.O.3
-
83
-
-
0028227930
-
In vitro selection of zinc fingers with altered DNA-binding specificity
-
JAMIESON AC, KIM SH, WELLS JA: In vitro selection of zinc fingers with altered DNA-binding specificity. Biochemistry (1994) 33:5689-5695.
-
(1994)
Biochemistry
, vol.33
, pp. 5689-5695
-
-
Jamieson, A.C.1
Kim, S.H.2
Wells, J.A.3
-
84
-
-
0027994717
-
Toward a code for the interactions of zinc fingers with DNA: Selection of randomized fingers displayed on phage
-
CHOO Y, KLUG A: Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phage. Proc. Natl. Acad. Sci. USA (1994) 91:11163-11167.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11163-11167
-
-
Choo, Y.1
Klug, A.2
-
85
-
-
0034691202
-
A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions
-
JOUNG JK, RAMM EI, PABO CO: A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions. Proc. Natl. Acad. Sci. USA (2000) 97:7382-7387.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7382-7387
-
-
Joung, J.K.1
Ramm, E.I.2
Pabo, C.O.3
-
86
-
-
0032981699
-
Toward controlling gene expression at will: Selection and design of zinc finger domains recognizing each of the 5′ -GNN-3′ DNA target sequences
-
SEGAL DJ, DREIER B, BEERLI RR, BARBAS CF 3rd: Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences. Proc. Natl. Acad. Sci. USA (1999) 96:2758-2763.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2758-2763
-
-
Segal, D.J.1
Dreier, B.2
Beerli, R.R.3
Barbas III, C.F.4
-
87
-
-
0035800769
-
Development of zinc finger domains for recognition of the 5′-ANN-3′ family of DNA sequences and their use in the construction of artificial transcription factors
-
DREIER B, BEERLI RR, SEGAL DJ, FLIPPIN JD, BARBAS CF 3rd: Development of zinc finger domains for recognition of the 5′ -ANN-3′ family of DNA sequences and their use in the construction of artificial transcription factors. J. Biol. Chem. (2001) 276:29466-29478.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29466-29478
-
-
Dreier, B.1
Beerli, R.R.2
Segal, D.J.3
Flippin, J.D.4
Barbas III, C.F.5
-
88
-
-
0031053362
-
A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
-
GREISMAN HA, PABO CO: A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites. Science (1997) 275:657-661.
-
(1997)
Science
, vol.275
, pp. 657-661
-
-
Greisman, H.A.1
Pabo, C.O.2
-
89
-
-
0034930363
-
A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter
-
ISALAN M, KLUG A, CHOO Y: A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter. Nat. Biotechnol. (2001) 19:656-660.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 656-660
-
-
Isalan, M.1
Klug, A.2
Choo, Y.3
-
90
-
-
0035815697
-
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A
-
LIU PQ, REBAR EJ, ZHANG L et al.: Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. J. Biol. Chem. (2001) 276:11323-11334.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11323-11334
-
-
Liu, P.Q.1
Rebar, E.J.2
Zhang, L.3
-
91
-
-
0036912846
-
Induction of angiogenesis in a mouse model using engineered transcription factors
-
REBAR EJ, HUANG Y, HICKEY R et al.: Induction of angiogenesis in a mouse model using engineered transcription factors. Nat. Med. (2002) 8:1427-1432.
-
(2002)
Nat. Med.
, vol.8
, pp. 1427-1432
-
-
Rebar, E.J.1
Huang, Y.2
Hickey, R.3
-
92
-
-
9144250992
-
Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors
-
SNOWDEN AW, ZHANG L, URNOV F et al.: Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors. Cancer Res. (2003) 63:8968-8976.
-
(2003)
Cancer Res.
, vol.63
, pp. 8968-8976
-
-
Snowden, A.W.1
Zhang, L.2
Urnov, F.3
-
93
-
-
0034652141
-
Positive and negative regulation of endogenous genes by designed transcription factors
-
BEERLI RR, DREIER B, BARBAS CF 3rd: Positive and negative regulation of endogenous genes by designed transcription factors. Proc. Natl. Acad. Sci. USA (2000) 97:1495-1500.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1495-1500
-
-
Beerli, R.R.1
Dreier, B.2
Barbas III, C.F.3
-
94
-
-
0034721877
-
Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene
-
ZHANG L, SPRATT SK, LIU Q et al.: Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene. J. Biol. Chem. (2000) 275:33850-33860.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33850-33860
-
-
Zhang, L.1
Spratt, S.K.2
Liu, Q.3
-
95
-
-
0142165907
-
Engineered zinc finger proteins for controlling stem cell fate
-
BARTSEVICH W, MILLER JC, CASE CC, PABO CO: Engineered zinc finger proteins for controlling stem cell fate. Stem Cells (2003) 21:632-637.
-
(2003)
Stem Cells
, vol.21
, pp. 632-637
-
-
Bartsevich, W.1
Miller, J.C.2
Case, C.C.3
Pabo, C.O.4
-
96
-
-
0037315952
-
Design of artificial transcription factors to selectively regulate the pro-apoptotic bar gene
-
FALKE D, FISHER M, YE D, JULIANO RL: Design of artificial transcription factors to selectively regulate the pro-apoptotic bar gene. Nucleic Acids Res. (2003) 31:e10.
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Falke, D.1
Fisher, M.2
Ye, D.3
Juliano, R.L.4
-
97
-
-
0033917833
-
Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries
-
BARTSEVICH VV, JULIANO RL: Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries. Mol. Pharmacol. (2000) 58:1-10.
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 1-10
-
-
Bartsevich, V.V.1
Juliano, R.L.2
-
98
-
-
0344284577
-
Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors
-
JOUVENOT Y, GINJALA V, ZHANG L et al.: Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors. Gene Ther. (2003) 10:513-522.
-
(2003)
Gene Ther.
, vol.10
, pp. 513-522
-
-
Jouvenot, Y.1
Ginjala, V.2
Zhang, L.3
-
99
-
-
0142027810
-
Zinc-finger protein-targeted gene regulation: Genomewide single-gene specificity
-
TAN S, GUSCHIN D, DAVALOS A et al.: Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity. Proc. Natl. Acad. Sci. USA (2003) 100:11997-12002.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11997-12002
-
-
Tan, S.1
Guschin, D.2
Davalos, A.3
-
100
-
-
0037338381
-
Scanning the human genome with combinatorial transcription factor libraries
-
BLANCAFORT P, MAGNENAT L, BARBAS CF 3rd: Scanning the human genome with combinatorial transcription factor libraries. Nat. Biotechnol. (2003) 21:269-274.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 269-274
-
-
Blancafort, P.1
Magnenat, L.2
Barbas III, C.F.3
-
101
-
-
0036007025
-
PPARγ knockdown by engineered transcription factors: Erogenous PPARγ2 but not PPARγ1 reactivates adipogenesis
-
REN D, COLLINGWOOD TN, REBAR EJ, WOLFFE AP, CAMP HS: PPARγ knockdown by engineered transcription factors: erogenous PPARγ2 but not PPARγ1 reactivates adipogenesis. Genes Dev. (2002) 16:27-32.
-
(2002)
Genes Dev.
, vol.16
, pp. 27-32
-
-
Ren, D.1
Collingwood, T.N.2
Rebar, E.J.3
Wolffe, A.P.4
Camp, H.S.5
-
102
-
-
0037205439
-
Activation of vascular endothelial growth factor A transcription in tumorigenic glioblastoma cell lines by an enhancer with cell type-specific DNase I accessibility
-
LIANG Y, LI XY, REBAR EJ et al.: Activation of vascular endothelial growth factor A transcription in tumorigenic glioblastoma cell lines by an enhancer with cell type-specific DNase I accessibility. J. Biol. Chem. (2002) 277:20087-20094.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 20087-20094
-
-
Liang, Y.1
Li, X.Y.2
Rebar, E.J.3
-
103
-
-
3843149434
-
Robust activation of vascular endothelial growth factor a using designed zinc finger protein transcription factors
-
Washington DC, USA (Abstract 1192)
-
REBAR EJ, ZHANG L, DENT C et al.: Robust activation of vascular endothelial growth factor a using designed zinc finger protein transcription factors. American Society ef Gene Therapy. Washington DC, USA (2003) (Abstract 1192).
-
(2003)
American Society of Gene Therapy
-
-
Rebar, E.J.1
Zhang, L.2
Dent, C.3
-
104
-
-
3843052496
-
Induction of angiogenesis in rat skeletal muscle using a designed zinc finger protein transcriptional activator targeted to vascular endothelial growth factor A (VEGF-A)
-
Washington DC, USA (Abstract 603)
-
JOHNSTONE B, VENSTROM K, ZHANG L et al.: Induction of angiogenesis in rat skeletal muscle using a designed zinc finger protein transcriptional activator targeted to vascular endothelial growth factor A (VEGF-A). American Society of Gene Therapy. Washington DC, USA (2003) (Abstract 603).
-
(2003)
American Society of Gene Therapy
-
-
Johnstone, B.1
Venstrom, K.2
Zhang, L.3
-
105
-
-
3843061302
-
A genetically engineered plasmid encoding a zinc finger vegf-activating transcription factor induces angiogenesis in the rabbits with hind-limb ischemia
-
Washington DC, USA (Abstract 855)
-
DAI Q, HUANG J, KLITZMAN B et al.: A genetically engineered plasmid encoding a zinc finger vegf-activating transcription factor induces angiogenesis in the rabbits with hind-limb ischemia. American Society of Gene Therapy. Washington DC, USA (2003) (Abstract 855).
-
(2003)
American Society of Gene Therapy
-
-
Dai, Q.1
Huang, J.2
Klitzman, B.3
-
106
-
-
85047694677
-
Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis
-
OZAWA CR, BANFI A, GLAZER NL et al.: Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis. J. Clin. Invest. (2004) 113:516-527.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 516-527
-
-
Ozawa, C.R.1
Banfi, A.2
Glazer, N.L.3
-
107
-
-
1242339670
-
Contribution of the Per/Arnt/Sim (PAS) domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators
-
CHAPMAN-SMITH A, LUTWYCHE JK, WHITELAW ML: Contribution of the Per/Arnt/Sim (PAS) domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators. J. Biol. Chem. (2004) 279:5353-5362.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5353-5362
-
-
Chapman-Smith, A.1
Lutwyche, J.K.2
Whitelaw, M.L.3
-
108
-
-
0030787469
-
Transactivation and inhibitory domains of hypoxia-inducible factor 1α. Modulation of transcriptional activity by oxygen tension
-
JIANG BH, ZHENG JZ, LEUNG SW, ROE R, SEMENZA GL: Transactivation and inhibitory domains of hypoxia-inducible factor 1α. Modulation of transcriptional activity by oxygen tension. J. Biol. Chem. (1997) 272:19253-19260.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19253-19260
-
-
Jiang, B.H.1
Zheng, J.Z.2
Leung, S.W.3
Roe, R.4
Semenza, G.L.5
-
109
-
-
0030587774
-
Zif268 protein-DNA complex refined at 1.6 A: A model system for understanding zinc finger-DNA interactions
-
ELROD-ERICKSON M, ROULD MA. NEKLUDOVA L, RABO CO: Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions. Structure (1996) 4:1171-1180.
-
(1996)
Structure
, vol.4
, pp. 1171-1180
-
-
Elrod-Erickson, M.1
Rould, M.A.2
Nekludova, L.3
Rabo, C.O.4
|