메뉴 건너뛰기




Volumn 163, Issue 8, 1999, Pages 4383-4391

Functional synergism of STAT6 with either NF-κB or PU.1 to mediate IL- 4-induced activation of IgE germline gene transcription

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 4; STAT6 PROTEIN; TRANSCRIPTION FACTOR;

EID: 0345062267     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (89)

References (47)
  • 1
    • 0027372064 scopus 로고
    • Mechanism and regulation of immunoglobulin isotype switching
    • Coffman, R. L., D. A. Lebmann, and P. Rothman. 1993. Mechanism and regulation of immunoglobulin isotype switching. Adv. Immunol. 54:229.
    • (1993) Adv. Immunol. , vol.54 , pp. 229
    • Coffman, R.L.1    Lebmann, D.A.2    Rothman, P.3
  • 2
    • 0030933777 scopus 로고    scopus 로고
    • The immunoglobulin class switch: Beyond "accessibility"
    • Snapper, C. M., K. B. Marcu, and P, Zelazowski. 1997. The immunoglobulin class switch: beyond "accessibility". Immunity 6:217.
    • (1997) Immunity , vol.6 , pp. 217
    • Snapper, C.M.1    Marcu, K.B.2    Zelazowski, P.3
  • 3
    • 0029931447 scopus 로고    scopus 로고
    • Immunoglobulin class switching
    • Stavnezer, J. 1996. Immunoglobulin class switching. Curr. Opin. Immunol. 8:199.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 199
    • Stavnezer, J.1
  • 4
    • 0028023208 scopus 로고
    • A bifunctional control element in the human IgE germline promoter involved in repression and IL-4 activation
    • Albrecht, B., S. Peiritsch, and M. Woisetschlaeger. 1994. A bifunctional control element in the human IgE germline promoter involved in repression and IL-4 activation. Int. Immunol. 6:1143.
    • (1994) Int. Immunol. , vol.6 , pp. 1143
    • Albrecht, B.1    Peiritsch, S.2    Woisetschlaeger, M.3
  • 5
    • 0027173826 scopus 로고
    • Regulation of the expression of human C∈ germline transcript: Identification of a novel IL-4 responsive element
    • Ichiki, T., W. Takahashi, and T. Watanabe. 1993. Regulation of the expression of human C∈ germline transcript: identification of a novel IL-4 responsive element. J. Immunol. 150:5408.
    • (1993) J. Immunol. , vol.150 , pp. 5408
    • Ichiki, T.1    Takahashi, W.2    Watanabe, T.3
  • 6
    • 0027331547 scopus 로고
    • Allergy-associated I ∈ and Fc∈ receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element
    • Kohler, I., and E. P. Rieber. 1993. Allergy-associated I ∈ and Fc∈ receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element. Eur. J. Immunol. 23:3066.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3066
    • Kohler, I.1    Rieber, E.P.2
  • 7
    • 0025942519 scopus 로고
    • Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line ∈; transcripts
    • Rothman, P., S. C. Li, B. Gorham, L. Glimcher, F. W. Alt, and M. Boothby. 1991. Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line ∈; transcripts. Mol. Cell. Biol. 11:5551.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5551
    • Rothman, P.1    Li, S.C.2    Gorham, B.3    Glimcher, L.4    Alt, F.W.5    Boothby, M.6
  • 8
    • 0028262965 scopus 로고
    • STF-IL-4: A novel IL-4-induced signal transducing factor
    • Schindler, C., H. Kashleva, A. Pemis, R. Pine, and P. Rothman. 1994. STF-IL-4: a novel IL-4-induced signal transducing factor. EMBO J. 13:1350.
    • (1994) EMBO J. , vol.13 , pp. 1350
    • Schindler, C.1    Kashleva, H.2    Pemis, A.3    Pine, R.4    Rothman, P.5
  • 9
    • 0029093023 scopus 로고
    • Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-γ activation site-like sequence upstream of the I∈ exon in a human B cell line: Evidence for the involvement of Janus kinase 3 and interleukin-4 stat
    • Fenghao, X., A. Saxon, A. Nguyen, Z. Ke, D. Diaz-Sanchez, and A. Nel. 1995. Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-γ activation site-like sequence upstream of the I∈ exon in a human B cell line: evidence for the involvement of Janus kinase 3 and interleukin-4 Stat. J. Clin. Invest. 96:907.
    • (1995) J. Clin. Invest. , vol.96 , pp. 907
    • Fenghao, X.1    Saxon, A.2    Nguyen, A.3    Ke, Z.4    Diaz-Sanchez, D.5    Nel, A.6
  • 11
    • 0030586670 scopus 로고    scopus 로고
    • The transcription factor B cell-specific activator protein is not involved in the IL-4-induced activation of the human IgE germline promoter
    • Albrecht, B., S. Peiritsch, B. Messner, and M. Woisetschläger. 1996. The transcription factor B cell-specific activator protein is not involved in the IL-4-induced activation of the human IgE germline promoter. J. Immunol 157:1538.
    • (1996) J. Immunol , vol.157 , pp. 1538
    • Albrecht, B.1    Peiritsch, S.2    Messner, B.3    Woisetschläger, M.4
  • 12
    • 0028258916 scopus 로고
    • The transcription factor BSAP (NF-HB) is essential for immunoglobulin germ-line ∈ transcription
    • Liao, F., B. K. Birshtein, M. Busslinger, and P. Rothman. 1994. The transcription factor BSAP (NF-HB) is essential for immunoglobulin germ-line ∈ transcription. J. Immunol. 152:2904.
    • (1994) J. Immunol. , vol.152 , pp. 2904
    • Liao, F.1    Birshtein, B.K.2    Busslinger, M.3    Rothman, P.4
  • 13
    • 0031570410 scopus 로고    scopus 로고
    • The transcription factor B cell-specific activator protein (BSAP) enhances both IL-4- and CD40-mediated activation of the human ∈ germline promoter
    • Thienes, C. P., L. de Monte, S. Monticelli, M. Busslinger, H. J Gould, and D. Vercelli. 1997. The transcription factor B cell-specific activator protein (BSAP) enhances both IL-4- and CD40-mediated activation of the human ∈ germline promoter. J. Immunol. 158:5874.
    • (1997) J. Immunol. , vol.158 , pp. 5874
    • Thienes, C.P.1    De Monte, L.2    Monticelli, S.3    Busslinger, M.4    Gould, H.J.5    Vercelli, D.6
  • 14
    • 0028917885 scopus 로고
    • Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline ∈ promoter: Regulation by NF-IL-4, a C/EBP family member and NF-κB/pSO
    • Delphin, S., and J. Stavnezer. 1995. Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline ∈ promoter: regulation by NF-IL-4, a C/EBP family member and NF-κB/pSO. J. Exp. Med. 181: 181.
    • (1995) J. Exp. Med. , vol.181 , pp. 181
    • Delphin, S.1    Stavnezer, J.2
  • 15
    • 0032529415 scopus 로고    scopus 로고
    • Synergistic activation of the germline ∈ promoter mediated by Stat6 and C/EBPβ
    • Mikita, T., M. Kurama, and U. Schindler. 1998. Synergistic activation of the germline ∈ promoter mediated by Stat6 and C/EBPβ. J. Immunol. 161:1822.
    • (1998) J. Immunol. , vol.161 , pp. 1822
    • Mikita, T.1    Kurama, M.2    Schindler, U.3
  • 16
    • 0031252357 scopus 로고    scopus 로고
    • Cooperation of binding sites for STAT6 and NFκB/rel in the IL-4-induced up-regulation of the human IgE germline promoter
    • Messner, B., A. M. Stütz, B. Albrecht, S. Peiritsch, and M. Woisetschläger. 1997. Cooperation of binding sites for STAT6 and NFκB/rel in the IL-4-induced up-regulation of the human IgE germline promoter. J. Immunol. 159:3330.
    • (1997) J. Immunol. , vol.159 , pp. 3330
    • Messner, B.1    Stütz, A.M.2    Albrecht, B.3    Peiritsch, S.4    Woisetschläger, M.5
  • 17
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51.
    • (1989) Gene , vol.77 , pp. 51
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 18
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 20
    • 0027494858 scopus 로고
    • PU.1 is a component of a multiprotein complex which binds an essential site in the immunoglobulin λ2-4 enhancer
    • Eisenbeis, C. F., H. Singh, and U. Storb. 1993. PU.1 is a component of a multiprotein complex which binds an essential site in the immunoglobulin λ2-4 enhancer. Mol. Cell. Biol. 13:6452.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6452
    • Eisenbeis, C.F.1    Singh, H.2    Storb, U.3
  • 21
    • 0025809504 scopus 로고
    • The c-Ets oncoprotein activates the stromylesin promoter through the same elements as several non-nuclear oncoproteins
    • Wasylyk, C., A. Gutman, R. Nicholson, and B. Wasylyk. 1991. The c-Ets oncoprotein activates the stromylesin promoter through the same elements as several non-nuclear oncoproteins. EMBO J. 10:1127.
    • (1991) EMBO J. , vol.10 , pp. 1127
    • Wasylyk, C.1    Gutman, A.2    Nicholson, R.3    Wasylyk, B.4
  • 22
    • 0030587128 scopus 로고    scopus 로고
    • Induction of the TNF-α promoter in the murine dendritic cell line 18 and the murine mast cell line CPII is differently regulated
    • Prieschl, E. E., G. G. Pendl, A. Elbe, E. Serfling, N. E. Harrer, G. Stingl, and T. Baumruker. 1996. Induction of the TNF-α promoter in the murine dendritic cell line 18 and the murine mast cell line CPII is differently regulated. J. Immunol. 157:2645.
    • (1996) J. Immunol. , vol.157 , pp. 2645
    • Prieschl, E.E.1    Pendl, G.G.2    Elbe, A.3    Serfling, E.4    Harrer, N.E.5    Stingl, G.6    Baumruker, T.7
  • 23
    • 0030966101 scopus 로고    scopus 로고
    • The role of Ets transcription factors in the development and function of the mammalian immune system
    • Bassuk, A. G., and J. M. Leiden. 1997. The role of Ets transcription factors in the development and function of the mammalian immune system. Adv. Immunol. 64:65.
    • (1997) Adv. Immunol. , vol.64 , pp. 65
    • Bassuk, A.G.1    Leiden, J.M.2
  • 24
    • 0031204428 scopus 로고    scopus 로고
    • Identification of a STAT6 domain required for IL-4-induced activation of transcription
    • Lu, B., M. Reichel, D. A. Fisher, J. F. Smith, and P. Rothman. 1997. Identification of a STAT6 domain required for IL-4-induced activation of transcription. J. Immunol. 159:1255.
    • (1997) J. Immunol. , vol.159 , pp. 1255
    • Lu, B.1    Reichel, M.2    Fisher, D.A.3    Smith, J.F.4    Rothman, P.5
  • 25
    • 0031570029 scopus 로고    scopus 로고
    • CD40 cross-linking induces Ig∈ germline transcripts in B cells via activation of NF-κB
    • Iciek, L. A., S. A. Delphin, and J. Stavnezer. 1997. CD40 cross-linking induces Ig∈ germline transcripts in B cells via activation of NF-κB. J. Immunol. 158: 4769.
    • (1997) J. Immunol. , vol.158 , pp. 4769
    • Iciek, L.A.1    Delphin, S.A.2    Stavnezer, J.3
  • 26
    • 0029073345 scopus 로고
    • Pip, a novel IRF family member, is a lymphoid specific, PU.1-dependent transcriptional activator
    • Eisenbeis, C. F., H. Singh, and U. Storb. 1995. Pip, a novel IRF family member, is a lymphoid specific, PU.1-dependent transcriptional activator. Genes Dev. 9:1377.
    • (1995) Genes Dev. , vol.9 , pp. 1377
    • Eisenbeis, C.F.1    Singh, H.2    Storb, U.3
  • 28
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    • Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity 4:313.
    • (1996) Immunity , vol.4 , pp. 313
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 29
    • 0031859134 scopus 로고    scopus 로고
    • STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination
    • Linehan, L. A., W. D. Warren, P. A. Thompson, M. J. Grusby, and M. T. Berton. 1998. STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination. J. Immunol 161:302.
    • (1998) J. Immunol , vol.161 , pp. 302
    • Linehan, L.A.1    Warren, W.D.2    Thompson, P.A.3    Grusby, M.J.4    Berton, M.T.5
  • 32
    • 0029099389 scopus 로고
    • Evidence for a CD40 response element, distinct from the IL-4 response element, in the germline ∈ promoter
    • Fujita, K., M. D. Jumper, K. Meek, and P. E. Lipsky. 1995. Evidence for a CD40 response element, distinct from the IL-4 response element, in the germline ∈ promoter. Int. Immunol. 7:1529.
    • (1995) Int. Immunol. , vol.7 , pp. 1529
    • Fujita, K.1    Jumper, M.D.2    Meek, K.3    Lipsky, P.E.4
  • 33
    • 0342378078 scopus 로고    scopus 로고
    • PU.1 negatively regulates the CD1 lc integrin gene promoter through recognition of the major transcriptional start site
    • Lopez-Rodriguez, C., and A. L. Corbi. 1997. PU.1 negatively regulates the CD1 lc integrin gene promoter through recognition of the major transcriptional start site. Eur. J. Immunol 27:1843.
    • (1997) Eur. J. Immunol , vol.27 , pp. 1843
    • Lopez-Rodriguez, C.1    Corbi, A.L.2
  • 34
    • 0030780188 scopus 로고    scopus 로고
    • PU.1/Pip and basic helix loop helix zipper transcription factors interact with binding sites in the CD20 promoter to help confer lineage- and stage-specific expression of CD20 in B-lymphocytes
    • Himmelmann, A., A. Riva, G. L. Wilson, B. P. Lucas, C. Thevenin, and J. H. Kehrl. 1997. PU.1/Pip and basic helix loop helix zipper transcription factors interact with binding sites in the CD20 promoter to help confer lineage- and stage-specific expression of CD20 in B-lymphocytes. Blood 90:3984.
    • (1997) Blood , vol.90 , pp. 3984
    • Himmelmann, A.1    Riva, A.2    Wilson, G.L.3    Lucas, B.P.4    Thevenin, C.5    Kehrl, J.H.6
  • 35
    • 0032031411 scopus 로고    scopus 로고
    • PU.1/Spi-1 is essential for the B cell-specific activity of the mouse CD72 promoter
    • Ying, H., J.-F. Chang, and J. R. Pames. 1998. PU.1/Spi-1 is essential for the B cell-specific activity of the mouse CD72 promoter. J, Immunol. 160:2287.
    • (1998) J, Immunol. , vol.160 , pp. 2287
    • Ying, H.1    Chang, J.-F.2    Pames, J.R.3
  • 36
    • 0028361784 scopus 로고
    • Restriction of Interferon γ responsiveness and basal expression of the myeloid human FcγR1b gene is mediated by a functional PU.1 site and a transcription initiator consensus
    • Eichbaum, Q. G., R. Iyer, D. P. Raven, C. Mathieu, and R. A. B. Ezekowitz. 1994. Restriction of Interferon γ responsiveness and basal expression of the myeloid human FcγR1b gene is mediated by a functional PU.1 site and a transcription initiator consensus. J. Exp. Med. 179:1985.
    • (1994) J. Exp. Med. , vol.179 , pp. 1985
    • Eichbaum, Q.G.1    Iyer, R.2    Raven, D.P.3    Mathieu, C.4    Ezekowitz, R.A.B.5
  • 37
    • 0029002732 scopus 로고
    • Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: Potential role of Ets family members
    • Lundgren, M., L. Ström, L.-O. Bergquist, S. Skog, T. Heiden, J. Stavnezer, and E. Severinson. 1995. Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members. Eur. J. Immunol. 25:2042.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2042
    • Lundgren, M.1    Ström, L.2    Bergquist, L.-O.3    Skog, S.4    Heiden, T.5    Stavnezer, J.6    Severinson, E.7
  • 38
    • 0025032511 scopus 로고
    • Structure and expression of germline ∈ transcripts in human B cells induced by interleukin 4 to switch to IgE production
    • Gauchat, J. F., D. A. Lebman, R. L. Coffman, H. Gascan, and J. E. De Vries. 1990. Structure and expression of germline ∈ transcripts in human B cells induced by interleukin 4 to switch to IgE production. J. Exp. Med. 172:463.
    • (1990) J. Exp. Med. , vol.172 , pp. 463
    • Gauchat, J.F.1    Lebman, D.A.2    Coffman, R.L.3    Gascan, H.4    De Vries, J.E.5
  • 39
    • 0027511495 scopus 로고
    • The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB
    • Hagemeier, C., A. Bannister, A. Cook, and T. Kouzarides. 1993. The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB. Proc. Natl. Acad. Sci. USA 90:1580.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1580
    • Hagemeier, C.1    Bannister, A.2    Cook, A.3    Kouzarides, T.4
  • 40
    • 0028813664 scopus 로고
    • A direct physical association between ETS and AP-1 transcription factors in normal human T cells
    • Bassuk, A. G., and J. M. Leiden. 1995. A direct physical association between ETS and AP-1 transcription factors in normal human T cells. Immunity. 3:223.
    • (1995) Immunity , vol.3 , pp. 223
    • Bassuk, A.G.1    Leiden, J.M.2
  • 41
    • 0028792116 scopus 로고
    • Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6β (C/EBPδ, CRP3)
    • Nagulapalli, S., J. M. R. Pongupala, and M. L. Atchison. 1995. Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6β (C/EBPδ, CRP3). J. Immunol. 155:4330.
    • (1995) J. Immunol. , vol.155 , pp. 4330
    • Nagulapalli, S.1    Pongupala, J.M.R.2    Atchison, M.L.3
  • 42
    • 0031842614 scopus 로고    scopus 로고
    • Interaction of Stat6 and NF-κB : Direct association and synergistic activation of interleukin-4-induced transcription
    • Shen, C.-H., and J. Stavnezer. 1998. Interaction of Stat6 and NF-κB : Direct association and synergistic activation of interleukin-4-induced transcription. Mol. Cell. Biol. 18:3395.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3395
    • Shen, C.-H.1    Stavnezer, J.2
  • 44
    • 0025086042 scopus 로고
    • The NF-κB transcription factor induces DNA bending which is modulated by its 65-kD subunit
    • Schreck, R., H. Zorbas, E.-L. Winnacker, and P. A. Baeuerle. 1990. The NF-κB transcription factor induces DNA bending which is modulated by its 65-kD subunit. Nucleic Acids Res. 18:6497.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 6497
    • Schreck, R.1    Zorbas, H.2    Winnacker, E.-L.3    Baeuerle, P.A.4
  • 45
    • 0028152658 scopus 로고
    • Cross-linking CD40 on B cells rapidly activates nuclear factor-κB
    • Berberich, I., G. L. Shu, and E. A. Clark. 1994. Cross-linking CD40 on B cells rapidly activates nuclear factor-κB. J. Immunol. 153:4357.
    • (1994) J. Immunol. , vol.153 , pp. 4357
    • Berberich, I.1    Shu, G.L.2    Clark, E.A.3
  • 46
    • 0026568296 scopus 로고
    • Modulation of IL-4 induced germline ∈ RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE production
    • Gauchat, J.-F., G. G. Aversa, H. Gascan, and J. E. de Vries. 1992. Modulation of IL-4 induced germline ∈ RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE production. Int. Immunol. 4:397.
    • (1992) Int. Immunol. , vol.4 , pp. 397
    • Gauchat, J.-F.1    Aversa, G.G.2    Gascan, H.3    De Vries, J.E.4
  • 47
    • 0031803277 scopus 로고    scopus 로고
    • Both PU.1 and nuclear factor-κB mediate lipopolysaccharide-induced HIV-1 long terminal repeat transcription in macrophages
    • Lodie, T. A., M. Reiner, S. Coniglio, G. Viglianti, and M. J. Fenton. 1998. Both PU.1 and nuclear factor-κB mediate lipopolysaccharide-induced HIV-1 long terminal repeat transcription in macrophages. J. Immunol. 161:268.
    • (1998) J. Immunol. , vol.161 , pp. 268
    • Lodie, T.A.1    Reiner, M.2    Coniglio, S.3    Viglianti, G.4    Fenton, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.