A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease

Journal of Bioinformatics and Computational Biology

Volumn 5, Issue 6, 2007, Pages 1297-1318

  Worth, Catherine L ^a   Bickerton, G Richard J ^a   Schreyer, Adrian ^a   Forman, Julia R ^a   Cheng, Tammy M K ^a   Lee, Semin ^a   Gong, Sungsam ^a   Burke, David F ^a   Blundell, Tom L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Comparative modeling; Disease association; Protein structure; Single nucleotide polymorphism

Indexed keywords

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; COMPUTER PROGRAM; DISEASE ASSOCIATION; DNA DETERMINATION; DNA STRUCTURE; GENETIC VARIABILITY; MEDICAL INFORMATION SYSTEM; MUTATION; NONSYNONYMOUS SINGLE NUCLEOTIDE POLYMORPHISM; PROTEIN DATABASE; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURAL HOMOLOGY;

COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DATABASES, GENETIC; DISEASE; HUMANS; MODELS, MOLECULAR; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN INTERACTION MAPPING; PROTEINS; SOFTWARE;

EID: 38049084041     PISSN: 02197200     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0219720007003120     Document Type: Article

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