Where did the BLOSUM62 alignment score matrix come from?

Nature Biotechnology

Volumn 22, Issue 8, 2004, Pages 1035-1036

  Eddy, Sean R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIX ALGEBRA; NATURAL SCIENCES;

SEQUENCE ALIGNMENT;

BIOTECHNOLOGY;

AMINO ACID SUBSTITUTION; CALCULATION; GENE FREQUENCY; PRIORITY JOURNAL; SCORING SYSTEM; SEQUENCE ALIGNMENT; SHORT SURVEY; STATISTICAL ANALYSIS;

ALGORITHMS; PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 3543047963     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0804-1035     Document Type: Short Survey

References (3)

1. Henikoff, J.G. Amino acid substitution matrices from protein blocks. Proc. Natl. Acad. Sci. USA 89, 10915-10919 (1992).
2. Karlin, S. & Altschul, S.F. Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes. Proc. Natl. Acad. Sci. USA 87, 2264-2268 (1990).
3. Altschul, S.F. Amino acid substitution matrices from an information theoretic perspective. J. Mol. Biol. 219, 555-565 (1991).