-
1
-
-
0034655976
-
Pharmacogenetics and future drug development and delivery
-
Roses AD: Pharmacogenetics and future drug development and delivery. Lancet 355, 1358-1361 (2000).
-
(2000)
Lancet
, vol.355
, pp. 1358-1361
-
-
Roses, A.D.1
-
2
-
-
85015078040
-
The double helix in clinical practice
-
Bell JI: The double helix in clinical practice. Nature 421, 414-416 (2003).
-
(2003)
Nature
, vol.421
, pp. 414-416
-
-
Bell, J.I.1
-
3
-
-
0037373275
-
Discovering genotypes underlying human phenotypes: Past successes for Mendelian disease, future approaches for complex diseases
-
Botstein D, Risch N: Discovering genotypes underlying human phenotypes: past successes for Mendelian disease, future approaches for complex diseases. Nature Genet. 33, 228-237 (2003).
-
(2003)
Nature Genet.
, vol.33
, pp. 228-237
-
-
Botstein, D.1
Risch, N.2
-
5
-
-
0742288585
-
The complex interplay among factors that influence allelic association
-
Zondervan KT, Cardon LR: The complex interplay among factors that influence allelic association. Nature Rev. Genet. 5, 89-100 (2003).
-
(2003)
Nature Rev. Genet.
, vol.5
, pp. 89-100
-
-
Zondervan, K.T.1
Cardon, L.R.2
-
6
-
-
18544380387
-
Parameters for reliable results in genetic association studies in common disease
-
Dahlman I, Eaves IA, Kosoy R et al.: Parameters for reliable results in genetic association studies in common disease. Nature Genet. 30, 149-150 (2002).
-
(2002)
Nature Genet.
, vol.30
, pp. 149-150
-
-
Dahlman, I.1
Eaves, I.A.2
Kosoy, R.3
-
7
-
-
0028871202
-
Susceptibility to human type 1 diabetes at IDDM2 is determinied by tandem repeat variation at the insulin gene minisatellite locus
-
Bennett ST, Lucassen AM, Gough SCL et al.: Susceptibility to human type 1 diabetes at IDDM2 is determinied by tandem repeat variation at the insulin gene minisatellite locus. Nature Genet. 9, 284-292 (1995).
-
(1995)
Nature Genet.
, vol.9
, pp. 284-292
-
-
Bennett, S.T.1
Lucassen, A.M.2
Gough, S.C.L.3
-
8
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda H, Howson JMM, Esposito L et al.: Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423, 506-511 (2003).
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.M.2
Esposito, L.3
-
9
-
-
7244234185
-
Differential genetic effects of ESR1 polymorphisms on osteoporosis outcomes
-
Ioannidis JPA, Ralston SH, Bennett ST et al.: Differential genetic effects of ESR1 polymorphisms on osteoporosis outcomes. JAMA 292, 2105-2114 (2004).
-
(2004)
JAMA
, vol.292
, pp. 2105-2114
-
-
Ioannidis, J.P.A.1
Ralston, S.H.2
Bennett, S.T.3
-
10
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
International Genome Sequencing Consortium
-
International Genome Sequencing Consortium: Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
-
11
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW et al.: The sequence of the human genome. Science 291, 1304-1351 (2001).
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
-
12
-
-
0026053092
-
Low nucleotide diversity in man
-
Li WH, Sadler LA: Low nucleotide diversity in man. Genetics 129, 513-523 (1991).
-
(1991)
Genetics
, vol.129
, pp. 513-523
-
-
Li, W.H.1
Sadler, L.A.2
-
13
-
-
0032524383
-
Large-scale identification, mapping, and genotyping of single nucleotide polymorphisms in the human genome
-
Wang DG, Fan JB, Siao CJ et al.: Large-scale identification, mapping, and genotyping of single nucleotide polymorphisms in the human genome. Science 280, 1077-1082 (1998).
-
(1998)
Science
, vol.280
, pp. 1077-1082
-
-
Wang, D.G.1
Fan, J.B.2
Siao, C.J.3
-
14
-
-
0032991552
-
Characterization of single nucleotide polymorphisms in coding regions of human genes
-
Cargill M, Altshuler D, Ireland J et al.: Characterization of single nucleotide polymorphisms in coding regions of human genes. Nature Genet. 22, 231-238 (1991).
-
(1991)
Nature Genet.
, vol.22
, pp. 231-238
-
-
Cargill, M.1
Altshuler, D.2
Ireland, J.3
-
15
-
-
0032990407
-
Patterns of single nucleotide polymorphisms in candidates genes for blood pressure homeostasis
-
Halushka MK, Fan JB, Bentley K et al.: Patterns of single nucleotide polymorphisms in candidates genes for blood pressure homeostasis. Nature Genet. 22, 239-247 (1999).
-
(1999)
Nature Genet.
, vol.22
, pp. 239-247
-
-
Halushka, M.K.1
Fan, J.B.2
Bentley, K.3
-
16
-
-
79959503826
-
The International HapMap Project
-
The International HapMap Consortium
-
The International HapMap Consortium: The International HapMap Project. Nature 426, 789-796 (2003).
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
17
-
-
0027021522
-
Biology and applications of human minisatellites loci
-
Armour JA, Jeffreys AJ: Biology and applications of human minisatellites loci. Curr. Opin. Genet. Dev. 6, 850-856 (1992).
-
(1992)
Curr. Opin. Genet. Dev.
, vol.6
, pp. 850-856
-
-
Armour, J.A.1
Jeffreys, A.J.2
-
18
-
-
0028240980
-
Chromosome-specific microsatellite sets for fluorescence-based, semi-automated genome mapping
-
Reed PW, Davies JL, Copeman JB et al.: Chromosome-specific microsatellite sets for fluorescence-based, semi-automated genome mapping. Nature Genet. 7, 390-395 (1994).
-
(1994)
Nature Genet.
, vol.7
, pp. 390-395
-
-
Reed, P.W.1
Davies, J.L.2
Copeman, J.B.3
-
20
-
-
13844313862
-
Whole-genome patterns of common DNA variation in three human populations
-
Hinds DA, Stuve LL, Nilsen GB et al.: Whole-genome patterns of common DNA variation in three human populations. Science 307, 1072-1079 (2005).
-
(2005)
Science
, vol.307
, pp. 1072-1079
-
-
Hinds, D.A.1
Stuve, L.L.2
Nilsen, G.B.3
-
21
-
-
0034789532
-
Haplotype tagging for the identification of common disease genes
-
Johnson GCL, Esposito L, Barratt BJ et al.: Haplotype tagging for the identification of common disease genes. Nature Genet. 29, 233-237 (2001).
-
(2001)
Nature Genet.
, vol.29
, pp. 233-237
-
-
Johnson, G.C.L.1
Esposito, L.2
Barratt, B.J.3
-
22
-
-
0037447974
-
SNP and haplotype variation in the human genome
-
Salisbury BA, Pungliya M, Choi JY, Jiang R, Sun XJ, Stephens C: SNP and haplotype variation in the human genome. Mutat. Res. 526, 53-61 (2003).
-
(2003)
Mutat. Res.
, vol.526
, pp. 53-61
-
-
Salisbury, B.A.1
Pungliya, M.2
Choi, J.Y.3
Jiang, R.4
Sun, X.J.5
Stephens, C.6
-
23
-
-
0019769456
-
Determination of nucleotide sequences in DNA
-
Sanger F: Determination of nucleotide sequences in DNA. Science 214, 1205-1210 (1981).
-
(1981)
Science
, vol.214
, pp. 1205-1210
-
-
Sanger, F.1
-
24
-
-
21444435888
-
Microfluidic devices for DNA sequencing: Sample preparation and electrophoretic analysis
-
Paegel BM, Blazej RG, Mathies RA: Microfluidic devices for DNA sequencing: sample preparation and electrophoretic analysis. Proc. Natl. Acad. Sci. USA 100, 5926-5931 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5926-5931
-
-
Paegel, B.M.1
Blazej, R.G.2
Mathies, R.A.3
-
25
-
-
1942499454
-
Advanced sequencing technologies: Methods and goals
-
Shendure J, Mitra RD, Varma C, Church GM: Advanced sequencing technologies: methods and goals. Nature Rev. Genet. 5, 335-344 (2004).
-
(2004)
Nature Rev. Genet.
, vol.5
, pp. 335-344
-
-
Shendure, J.1
Mitra, R.D.2
Varma, C.3
Church, G.M.4
-
26
-
-
21444433979
-
The $1,000 Human Genome - Implications for Life Sciences, Healthcare and IT
-
IDC Publishers, Framingham, USA
-
Zimmerman Z: The $1,000 Human Genome - Implications for Life Sciences, Healthcare and IT. IDC Publishers, Framingham, USA (2004).
-
(2004)
-
-
Zimmerman, Z.1
-
27
-
-
0037474152
-
Zero-mode waveguides for single-molecule analysis at high concentrations
-
Levine MJ et al: Zero-mode waveguides for single-molecule analysis at high concentrations. Science 299, 682-686 (2003).
-
(2003)
Science
, vol.299
, pp. 682-686
-
-
Levine, M.J.1
-
28
-
-
0037705455
-
Incorporation of reporter molecule-labeled nucleotides by DNA polymerases II. High-density labelling of natural DNA
-
Tasara T, Angerer B, Damond M et al.: Incorporation of reporter molecule-labeled nucleotides by DNA polymerases II. High-density labelling of natural DNA. Nucleic Acids Res. 31(10), 2636-2646 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, Issue.10
, pp. 2636-2646
-
-
Tasara, T.1
Angerer, B.2
Damond, M.3
-
29
-
-
0035901674
-
High-density labeling of DNA: Preparation and characterization of the target material for single-molecule sequencing
-
Brakmann S, Löbermann S: High-density labeling of DNA: preparation and characterization of the target material for single-molecule sequencing. Angew. Chem. Int. Ed. 40(8), 1427-1429 (2001).
-
(2001)
Angew. Chem. Int. Ed.
, vol.40
, Issue.8
, pp. 1427-1429
-
-
Brakmann, S.1
Löbermann, S.2
-
30
-
-
0034177819
-
Nanopores and nucleic acids: Prospects for ultrarapid sequencing
-
Deamer DW, Akeson M: Nanopores and nucleic acids: prospects for ultrarapid sequencing. Trends Biotechnol. 4, 147-151 (2000).
-
(2000)
Trends Biotechnol.
, vol.4
, pp. 147-151
-
-
Deamer, D.W.1
Akeson, M.2
-
31
-
-
14844290867
-
Recognizing a single base in an individual DNA strand: A step toward DNA sequencing in nanopores
-
Ashkenasy N, Sanchez-Quesada J, Bayley M, Ghadiri MR: Recognizing a single base in an individual DNA strand: a step toward DNA sequencing in nanopores. Angew. Chem. Int. Ed. Engl. 44(9), 1401-1404 (2005).
-
(2005)
Angew Chem. Int. Ed. Engl.
, vol.44
, Issue.9
, pp. 1401-1404
-
-
Ashkenasy, N.1
Sanchez-Quesada, J.2
Bayley, M.3
Ghadiri, M.R.4
-
32
-
-
0037388048
-
Sequence information can be obtained from single DNA molecules
-
Braslavsky I, Hebert B, Kartalov E, Quake SR: Sequence information can be obtained from single DNA molecules. Proc. Natl. Acad. Sci. USA 100, 3960-3964 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3960-3964
-
-
Braslavsky, I.1
Hebert, B.2
Kartalov, E.3
Quake, S.R.4
-
33
-
-
0033573165
-
In situ localized amplification and contact replication of many individual DNA molecules
-
Mitra RD, Church GM: In situ localized amplification and contact replication of many individual DNA molecules. Nucleic Acids Res. 27, e34 (1999).
-
(1999)
Nucleic Acids Res.
, vol.27
-
-
Mitra, R.D.1
Church, G.M.2
-
34
-
-
0038285034
-
Digital genotyping and haplotyping with polymerase colonies
-
Mitra RD, Burry VL, Shendure J, Williams BR, Housman DE, Church GM: Digital genotyping and haplotyping with polymerase colonies. Proc. Natl Acad. Sci. USA 100, 5926-5931 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5926-5931
-
-
Mitra, R.D.1
Burry, V.L.2
Shendure, J.3
Williams, B.R.4
Housman, D.E.5
Church, G.M.6
-
35
-
-
0034667196
-
Solid phase DNA amplification: Characterisation of primer attachment and amplification mechanisms
-
Adessi C, Matton G, Ayala G et al. Solid phase DNA amplification: characterisation of primer attachment and amplification mechanisms. Nucleic Acids Res. 15, e87 (2000).
-
(2000)
Nucleic Acids Res.
, vol.15
-
-
Adessi, C.1
Matton, G.2
Ayala, G.3
-
36
-
-
12944293179
-
In vitro cloning of complex mixtures of DNA on microbeads: Physical separation of diffefentially expressed cDNAs
-
Brenner S, Johnson M, Bridgham J et al.: In vitro cloning of complex mixtures of DNA on microbeads: Physical separation of diffefentially expressed cDNAs. Proc. Natl Acad. Sci. USA 97, 1665-1670 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1665-1670
-
-
Brenner, S.1
Johnson, M.2
Bridgham, J.3
-
37
-
-
0348251333
-
A massively parallel PicoTiterPlate™ based platform for discrete picoliter-scale polymerase chain reactions
-
Leamon JH, Lee WL, Tartaro KR et al.: A massively parallel PicoTiterPlate™ based platform for discrete picoliter-scale polymerase chain reactions. Electrophoresis 24, 3769-3777 (2003).
-
(2003)
Electrophoresis
, vol.24
, pp. 3769-3777
-
-
Leamon, J.H.1
Lee, W.L.2
Tartaro, K.R.3
-
38
-
-
0034130561
-
Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays
-
Brenner S, Johnson M, Bridgham J et al.: Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays. Nature Biotechnol. 6, 630-634 (2000).
-
(2000)
Nature Biotechnol.
, vol.6
, pp. 630-634
-
-
Brenner, S.1
Johnson, M.2
Bridgham, J.3
-
39
-
-
0032784908
-
Interspersed repeats and other mementos of transposable elements in mammalian genomes
-
Smit AFA: Interspersed repeats and other mementos of transposable elements in mammalian genomes. Curr. Opin. Genet. Dev. 9, 657-663 (1999).
-
(1999)
Curr. Opin. Genet. Dev.
, vol.9
, pp. 657-663
-
-
Smit, A.F.A.1
|