Using model proteins to quantify the effects of pathogenic mutations in Ig-like proteins

Journal of Biological Chemistry

Volumn 281, Issue 34, 2006, Pages 24216-24226

  Randles, Lucy G ^a   Lappalainen, Ilkka ^a   Fowler, Susan B ^a   Moore, Benjamin ^a,b   Hamill, Stefan J ^a   Clarke, Jane ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOMEDICAL ENGINEERING; CHARACTERIZATION; CYTOLOGY; DISEASES; MUTAGENESIS;

BIOPHYSICAL CHARACTERIZATION; DISEASE CAUSING MUTATIONS; MUTATIONS; PATHOGENIC MUTATIONS;

PROTEINS;

IMMUNOGLOBULIN; MUTANT PROTEIN; PROTEIN IL2R GAMMA; PROTEIN L1; UNCLASSIFIED DRUG;

ARTICLE; DISEASE SEVERITY; LIGAND BINDING; MUTATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; THERMOSTABILITY;

GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNOGLOBULINS; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; MODELS, MOLECULAR; MUTATION; NEURAL CELL ADHESION MOLECULE L1; PREDICTIVE VALUE OF TESTS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN; SEQUENCE ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33747736184     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603593200     Document Type: Article

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