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Volumn 193, Issue 1-2, 2008, Pages 1-11

Foxp3+ regulatory T cells in the control of experimental CNS autoimmune disease

Author keywords

Autoimmunity; Immunotherapy; Multiple sclerosis; T regulatory cells; Tolerance

Indexed keywords

TRANSCRIPTION FACTOR FOXP3;

EID: 37849027594     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2007.11.016     Document Type: Review
Times cited : (153)

References (112)
  • 1
    • 0017709840 scopus 로고
    • Evidence for suppressor cells in Lewis rats' experimental allergic encephalomyelitis
    • Adda D.H., Beraud E., and Depieds R. Evidence for suppressor cells in Lewis rats' experimental allergic encephalomyelitis. Eur. J. Immunol. 7 (1977) 620-623
    • (1977) Eur. J. Immunol. , vol.7 , pp. 620-623
    • Adda, D.H.1    Beraud, E.2    Depieds, R.3
  • 3
    • 0035675871 scopus 로고    scopus 로고
    • Peptide-based immunotherapy of autoimmunity: a path of puzzles, paradoxes and possibilities
    • Anderton S.M. Peptide-based immunotherapy of autoimmunity: a path of puzzles, paradoxes and possibilities. Immunology 104 (2001) 367-376
    • (2001) Immunology , vol.104 , pp. 367-376
    • Anderton, S.M.1
  • 4
    • 33646482572 scopus 로고    scopus 로고
    • Avoiding autoimmune disease - T cells know their limits
    • Anderton S.M. Avoiding autoimmune disease - T cells know their limits. Trends Immunol. 27 (2006) 208-214
    • (2006) Trends Immunol. , vol.27 , pp. 208-214
    • Anderton, S.M.1
  • 5
    • 0031966915 scopus 로고    scopus 로고
    • Hierarchy in the ability of T cell epitopes to induce peripheral tolerance to antigens from myelin
    • Anderton S.M., and Wraith D.C. Hierarchy in the ability of T cell epitopes to induce peripheral tolerance to antigens from myelin. Eur. J. Immunol. 28 (1998) 1251-1261
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1251-1261
    • Anderton, S.M.1    Wraith, D.C.2
  • 6
    • 0033141481 scopus 로고    scopus 로고
    • Mechanisms of central and peripheral T-cell tolerance: lessons from experimental models of multiple sclerosis
    • Anderton S., Burkhart C., Metzler B., and Wraith D. Mechanisms of central and peripheral T-cell tolerance: lessons from experimental models of multiple sclerosis. Immunol. Rev. 169 (1999) 123-137
    • (1999) Immunol. Rev. , vol.169 , pp. 123-137
    • Anderton, S.1    Burkhart, C.2    Metzler, B.3    Wraith, D.4
  • 9
    • 2542420993 scopus 로고    scopus 로고
    • In vivo instruction of suppressor commitment in naive T cells
    • Apostolou I., and von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199 (2004) 1401-1408
    • (2004) J. Exp. Med. , vol.199 , pp. 1401-1408
    • Apostolou, I.1    von Boehmer, H.2
  • 10
    • 33845379986 scopus 로고    scopus 로고
    • Rapamycin promotes expansion of functional CD4+CD25 +FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
    • Battaglia M., Stabilini A., Migliavacca B., Horejs-Hoeck J., Kaupper T., and Roncarolo M.G. Rapamycin promotes expansion of functional CD4+CD25 +FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients. J. Immunol. 177 (2006) 8338-8347
    • (2006) J. Immunol. , vol.177 , pp. 8338-8347
    • Battaglia, M.1    Stabilini, A.2    Migliavacca, B.3    Horejs-Hoeck, J.4    Kaupper, T.5    Roncarolo, M.G.6
  • 11
    • 1342303410 scopus 로고    scopus 로고
    • Analysis of autoreactive CD4 T cells in experimental autoimmune encephalomyelitis after primary and secondary challenge using MHC class II tetramers
    • Bischof F., Hofmann M., Schumacher T.N.M., Vyth-Dreese F.A., Weissert R., Schild H., Kruisbeek A.M., and Melms A. Analysis of autoreactive CD4 T cells in experimental autoimmune encephalomyelitis after primary and secondary challenge using MHC class II tetramers. J. Immunol. 172 (2004) 2878-2884
    • (2004) J. Immunol. , vol.172 , pp. 2878-2884
    • Bischof, F.1    Hofmann, M.2    Schumacher, T.N.M.3    Vyth-Dreese, F.A.4    Weissert, R.5    Schild, H.6    Kruisbeek, A.M.7    Melms, A.8
  • 13
    • 33750833099 scopus 로고    scopus 로고
    • Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells
    • Brode S., Raine T., Zaccone P., and Cooke A. Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells. J. Immunol. 177 (2006) 6603-6612
    • (2006) J. Immunol. , vol.177 , pp. 6603-6612
    • Brode, S.1    Raine, T.2    Zaccone, P.3    Cooke, A.4
  • 14
    • 0032821774 scopus 로고    scopus 로고
    • Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10
    • Burkhart C., Liu G.Y., Anderton S.M., Metzler B., and Wraith D.C. Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: a role for IL-10. Int. Immunol. 11 (1999) 1625-1634
    • (1999) Int. Immunol. , vol.11 , pp. 1625-1634
    • Burkhart, C.1    Liu, G.Y.2    Anderton, S.M.3    Metzler, B.4    Wraith, D.C.5
  • 15
    • 15244361536 scopus 로고    scopus 로고
    • CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease
    • Cao D., van Vollenhoven R., Klareskog L., Trollmo C., and Malmstrom V. CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease. Arthritis Res. Ther. 6 (2004) R335-R346
    • (2004) Arthritis Res. Ther. , vol.6
    • Cao, D.1    van Vollenhoven, R.2    Klareskog, L.3    Trollmo, C.4    Malmstrom, V.5
  • 18
    • 27144483896 scopus 로고    scopus 로고
    • CD3-specific antibodies restore self-tolerance: mechanisms and clinical applications
    • Chatenoud L. CD3-specific antibodies restore self-tolerance: mechanisms and clinical applications. Curr. Opin. Immunol. 17 (2005) 632-637
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 632-637
    • Chatenoud, L.1
  • 19
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
    • Chen Y., Kuchroo V.K., Inobe J., Hafler D.A., and Weiner H.L. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265 (1994) 1237-1240
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 20
    • 33747414436 scopus 로고    scopus 로고
    • Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3+CD4+CD25+ T regulatory cells in vivo and enhances their capacity to suppress EAE
    • Chen X., Oppenheim J.J., Winkler-Pickett R.T., Ortaldo J.R., and Howard O.M.Z. Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3+CD4+CD25+ T regulatory cells in vivo and enhances their capacity to suppress EAE. Eur. J. Immunol. 36 (2006) 2139-2149
    • (2006) Eur. J. Immunol. , vol.36 , pp. 2139-2149
    • Chen, X.1    Oppenheim, J.J.2    Winkler-Pickett, R.T.3    Ortaldo, J.R.4    Howard, O.M.Z.5
  • 22
    • 2142806632 scopus 로고    scopus 로고
    • Autoreactive T cells persist in rats protected against experimental autoimmune encephalomyelitis and can be activated through stimulation of innate immunity
    • Conant S.B., and Swanborg R.H. Autoreactive T cells persist in rats protected against experimental autoimmune encephalomyelitis and can be activated through stimulation of innate immunity. J. Immunol. 172 (2004) 5322-5328
    • (2004) J. Immunol. , vol.172 , pp. 5322-5328
    • Conant, S.B.1    Swanborg, R.H.2
  • 23
    • 0035159581 scopus 로고    scopus 로고
    • Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis
    • Cua D.J., Hutchins B., LaFace D.M., Stohlman S.A., and Coffman R.L. Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis. J. Immunol. 166 (2001) 602-608
    • (2001) J. Immunol. , vol.166 , pp. 602-608
    • Cua, D.J.1    Hutchins, B.2    LaFace, D.M.3    Stohlman, S.A.4    Coffman, R.L.5
  • 24
    • 33947644716 scopus 로고    scopus 로고
    • Cutting edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells
    • Davidson T.S., Dipaolo R.J., Andersson J., and Shevach E.M. Cutting edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells. J. Immunol. 178 (2007) 4022-4026
    • (2007) J. Immunol. , vol.178 , pp. 4022-4026
    • Davidson, T.S.1    Dipaolo, R.J.2    Andersson, J.3    Shevach, E.M.4
  • 27
    • 33846817153 scopus 로고    scopus 로고
    • Increased frequency of CD4+ CD25+ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients
    • Feger U., Luther C., Poeschel S., Melms A., Tolosa E., and Wiendl H. Increased frequency of CD4+ CD25+ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients. Clin. Exp. Immunol. 147 (2007) 412-418
    • (2007) Clin. Exp. Immunol. , vol.147 , pp. 412-418
    • Feger, U.1    Luther, C.2    Poeschel, S.3    Melms, A.4    Tolosa, E.5    Wiendl, H.6
  • 28
    • 32944458828 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide induces regulatory T cells during experimental autoimmune encephalomyelitis
    • Fernadez-Martin A., Gonzalez-Rey E., Chorny A., Ganea D., and Delgado M. Vasoactive intestinal peptide induces regulatory T cells during experimental autoimmune encephalomyelitis. Eur. J. Immunol. 36 (2006) 318-326
    • (2006) Eur. J. Immunol. , vol.36 , pp. 318-326
    • Fernadez-Martin, A.1    Gonzalez-Rey, E.2    Chorny, A.3    Ganea, D.4    Delgado, M.5
  • 32
  • 33
    • 0024533021 scopus 로고
    • Molecular mimicry as a mechanism for virus-induced autoimmunity
    • Fujinami R.S., and Oldstone M.B. Molecular mimicry as a mechanism for virus-induced autoimmunity. Immunol. Res. 8 (1989) 3-15
    • (1989) Immunol. Res. , vol.8 , pp. 3-15
    • Fujinami, R.S.1    Oldstone, M.B.2
  • 34
    • 33244469494 scopus 로고    scopus 로고
    • CD25 regulatory T cells determine secondary but not primary remission in EAE: impact on long-term disease progression
    • Gartner D., Hoff H., Gimsa U., Burmester G.R., and Brunner-Weinzierl M.C. CD25 regulatory T cells determine secondary but not primary remission in EAE: impact on long-term disease progression. J. Neuroimmunol. 172 (2006) 73-84
    • (2006) J. Neuroimmunol. , vol.172 , pp. 73-84
    • Gartner, D.1    Hoff, H.2    Gimsa, U.3    Burmester, G.R.4    Brunner-Weinzierl, M.C.5
  • 36
    • 30444445129 scopus 로고    scopus 로고
    • How to drain without lymphatics? Dendritic cells migrate from the cerebrospinal fluid to the B-cell follicles of cervical lymph nodes
    • Hatterer E., Davoust N., Didier-Bazes M., Vuaillat C., Malcus C., Belin M.F., and Nataf S. How to drain without lymphatics? Dendritic cells migrate from the cerebrospinal fluid to the B-cell follicles of cervical lymph nodes. Blood 107 (2006) 806-812
    • (2006) Blood , vol.107 , pp. 806-812
    • Hatterer, E.1    Davoust, N.2    Didier-Bazes, M.3    Vuaillat, C.4    Malcus, C.5    Belin, M.F.6    Nataf, S.7
  • 37
    • 2942523789 scopus 로고    scopus 로고
    • Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo
    • Hawiger D., Masilamani R.F., Bettelli E., Kuchroo V.K., and Nussenzweig M.C. Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo. Immunity 20 (2004) 695-705
    • (2004) Immunity , vol.20 , pp. 695-705
    • Hawiger, D.1    Masilamani, R.F.2    Bettelli, E.3    Kuchroo, V.K.4    Nussenzweig, M.C.5
  • 38
    • 33748624618 scopus 로고    scopus 로고
    • Immunological tolerance using synthetic peptides - basic mechanisms and clinical application
    • Hochweller K., Sweenie C.H., and Anderton S.M. Immunological tolerance using synthetic peptides - basic mechanisms and clinical application. Curr. Mol. Med. 6 (2006) 631-643
    • (2006) Curr. Mol. Med. , vol.6 , pp. 631-643
    • Hochweller, K.1    Sweenie, C.H.2    Anderton, S.M.3
  • 39
    • 0019523739 scopus 로고
    • Regulation of experimental allergic encephalomyelitis. III. Demonstration of effector cells in tolerant rats
    • Holda J.H., and Swanborg R.H. Regulation of experimental allergic encephalomyelitis. III. Demonstration of effector cells in tolerant rats. Eur. J. Immunol. 11 (1981) 338-340
    • (1981) Eur. J. Immunol. , vol.11 , pp. 338-340
    • Holda, J.H.1    Swanborg, R.H.2
  • 41
    • 0033136302 scopus 로고    scopus 로고
    • Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • Itoh M., Takahashi T., Sakaguchi N., Kuniyasu Y., Shimizu J., Otsuka F., and Sakaguchi S. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162 (1999) 5317-5326
    • (1999) J. Immunol. , vol.162 , pp. 5317-5326
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3    Kuniyasu, Y.4    Shimizu, J.5    Otsuka, F.6    Sakaguchi, S.7
  • 42
    • 0024341132 scopus 로고
    • CD4+ suppressor cells differentially affect the production of IFN-gamma by effector cells of experimental autoimmune encephalomyelitis
    • Karpus W.J., and Swanborg R.H. CD4+ suppressor cells differentially affect the production of IFN-gamma by effector cells of experimental autoimmune encephalomyelitis. J. Immunol. 143 (1989) 3492-3497
    • (1989) J. Immunol. , vol.143 , pp. 3492-3497
    • Karpus, W.J.1    Swanborg, R.H.2
  • 43
    • 0025978235 scopus 로고
    • CD4+ suppressor cells inhibit the function of effector cells of experimental autoimmune encephalomyelitis through a mechanism involving transforming growth factor-beta
    • Karpus W.J., and Swanborg R.H. CD4+ suppressor cells inhibit the function of effector cells of experimental autoimmune encephalomyelitis through a mechanism involving transforming growth factor-beta. J. Immunol. 146 (1991) 1163-1168
    • (1991) J. Immunol. , vol.146 , pp. 1163-1168
    • Karpus, W.J.1    Swanborg, R.H.2
  • 44
    • 0026696776 scopus 로고
    • CD4+ suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion
    • Karpus W.J., Gould K.E., and Swanborg R.H. CD4+ suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion. Eur. J. Immunol. 22 (1992) 1757-1763
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1757-1763
    • Karpus, W.J.1    Gould, K.E.2    Swanborg, R.H.3
  • 46
    • 0020463170 scopus 로고
    • Regulation of experimental allergic encephalomyelitis. Part 4. Further characterization of postrecovery suppressor cells
    • Killen J.A., and Swanborg R.H. Regulation of experimental allergic encephalomyelitis. Part 4. Further characterization of postrecovery suppressor cells. J. Neuroimmunol. 3 (1982) 159-166
    • (1982) J. Neuroimmunol. , vol.3 , pp. 159-166
    • Killen, J.A.1    Swanborg, R.H.2
  • 47
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim J.M., Rasmussen J.P., and Rudensky A.Y. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8 (2007) 191-197
    • (2007) Nat. Immunol. , vol.8 , pp. 191-197
    • Kim, J.M.1    Rasmussen, J.P.2    Rudensky, A.Y.3
  • 48
    • 33746930267 scopus 로고    scopus 로고
    • Response to comment on "Cutting Edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells"
    • Kohm A.P., and Miller S.D. Response to comment on "Cutting Edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells". J. Immunol. 177 (2006) 2037-2038
    • (2006) J. Immunol. , vol.177 , pp. 2037-2038
    • Kohm, A.P.1    Miller, S.D.2
  • 49
    • 0036838536 scopus 로고    scopus 로고
    • Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • Kohm A.P., Carpentier P.A., Anger H.A., and Miller S.D. Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. 169 (2002) 4712-4716
    • (2002) J. Immunol. , vol.169 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 50
    • 33644841622 scopus 로고    scopus 로고
    • Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells
    • Kohm A.P., McMahon J.S., Podojil J.R., Begolka W.S., DeGutes M., Kasprowicz D.J., Ziegler S.F., and Miller S.D. Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells. J. Immunol. 176 (2006) 3301-3305
    • (2006) J. Immunol. , vol.176 , pp. 3301-3305
    • Kohm, A.P.1    McMahon, J.S.2    Podojil, J.R.3    Begolka, W.S.4    DeGutes, M.5    Kasprowicz, D.J.6    Ziegler, S.F.7    Miller, S.D.8
  • 53
    • 0028102655 scopus 로고
    • High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
    • Lafaille J.J., Nagashima K., Katsuki M., and Tonegawa S. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell 78 (1994) 399-408
    • (1994) Cell , vol.78 , pp. 399-408
    • Lafaille, J.J.1    Nagashima, K.2    Katsuki, M.3    Tonegawa, S.4
  • 54
    • 0018715997 scopus 로고
    • Effect of cyclophosphamide on suppressor cell activity in mice unresponsive to EAE
    • Lando Z., Teitelbaum D., and Arnon R. Effect of cyclophosphamide on suppressor cell activity in mice unresponsive to EAE. J. Immunol. 123 (1979) 2156-2160
    • (1979) J. Immunol. , vol.123 , pp. 2156-2160
    • Lando, Z.1    Teitelbaum, D.2    Arnon, R.3
  • 55
    • 17644401678 scopus 로고    scopus 로고
    • Peptide-based therapeutic vaccines for allergic and autoimmune diseases
    • Larche M., and Wraith D.C. Peptide-based therapeutic vaccines for allergic and autoimmune diseases. Nat. Med. 11 (2005) S69-S76
    • (2005) Nat. Med. , vol.11
    • Larche, M.1    Wraith, D.C.2
  • 57
    • 33646596928 scopus 로고    scopus 로고
    • Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE
    • Liu Y., Teige I., Birnir B., and Issazadeh-Navikas S. Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE. Nat. Med. 12 (2006) 518-525
    • (2006) Nat. Med. , vol.12 , pp. 518-525
    • Liu, Y.1    Teige, I.2    Birnir, B.3    Issazadeh-Navikas, S.4
  • 58
    • 0022178893 scopus 로고
    • High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61
    • Lowenthal J.W., Corthesy P., Tougne C., Lees R., MacDonald H.R., and Nabholz M. High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61. J. Immunol. 135 (1985) 3988-3994
    • (1985) J. Immunol. , vol.135 , pp. 3988-3994
    • Lowenthal, J.W.1    Corthesy, P.2    Tougne, C.3    Lees, R.4    MacDonald, H.R.5    Nabholz, M.6
  • 59
    • 33947283177 scopus 로고    scopus 로고
    • B cell regulation of CD4+CD25+ T regulatory cells and IL-10 via B7 is essential for recovery from experimental autoimmune encephalomyelitis
    • Mann M.K., Maresz K., Shriver L.P., Tan Y., and Dittel B.N. B cell regulation of CD4+CD25+ T regulatory cells and IL-10 via B7 is essential for recovery from experimental autoimmune encephalomyelitis. J. Immunol. 178 (2007) 3447-3456
    • (2007) J. Immunol. , vol.178 , pp. 3447-3456
    • Mann, M.K.1    Maresz, K.2    Shriver, L.P.3    Tan, Y.4    Dittel, B.N.5
  • 60
    • 17144400393 scopus 로고    scopus 로고
    • TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
    • Marie J.C., Letterio J.J., Gavin M., and Rudensky A.Y. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J. Exp. Med. 201 (2005) 1061-1067
    • (2005) J. Exp. Med. , vol.201 , pp. 1061-1067
    • Marie, J.C.1    Letterio, J.J.2    Gavin, M.3    Rudensky, A.Y.4
  • 61
    • 23844455192 scopus 로고    scopus 로고
    • Expansion of functional endogenous antigen-specific CD4 +CD25+ regulatory T cells from nonobese diabetic mice
    • Masteller E.L., Warner M.R., Tang Q., Tarbell K.V., McDevitt H., and Bluestone J.A. Expansion of functional endogenous antigen-specific CD4 +CD25+ regulatory T cells from nonobese diabetic mice. J. Immunol. 175 (2005) 3053-3059
    • (2005) J. Immunol. , vol.175 , pp. 3053-3059
    • Masteller, E.L.1    Warner, M.R.2    Tang, Q.3    Tarbell, K.V.4    McDevitt, H.5    Bluestone, J.A.6
  • 62
    • 0037450740 scopus 로고    scopus 로고
    • Prevention of arthritis by interleukin 10-producing B cells
    • Mauri C., Gray D., Mushtaq N., and Londei M. Prevention of arthritis by interleukin 10-producing B cells. J. Exp. Med. 197 (2003) 489-501
    • (2003) J. Exp. Med. , vol.197 , pp. 489-501
    • Mauri, C.1    Gray, D.2    Mushtaq, N.3    Londei, M.4
  • 63
    • 4644244732 scopus 로고    scopus 로고
    • Activation thresholds determine susceptibility to peptide-induced tolerance in a heterogeneous myelin-reactive T cell repertoire
    • McCue D., Ryan K.R., Wraith D.C., and Anderton S.M. Activation thresholds determine susceptibility to peptide-induced tolerance in a heterogeneous myelin-reactive T cell repertoire. J. Neuroimmunol. 156 (2004) 96-106
    • (2004) J. Neuroimmunol. , vol.156 , pp. 96-106
    • McCue, D.1    Ryan, K.R.2    Wraith, D.C.3    Anderton, S.M.4
  • 64
    • 0023856205 scopus 로고
    • Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis
    • McDonald A.H., and Swanborg R.H. Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis. J. Immunol. 140 (1988) 1132-1138
    • (1988) J. Immunol. , vol.140 , pp. 1132-1138
    • McDonald, A.H.1    Swanborg, R.H.2
  • 65
    • 23844478869 scopus 로고    scopus 로고
    • Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system
    • McGeachy M.J., Stephens L.A., and Anderton S.M. Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system. J. Immunol. 175 (2005) 3025-3032
    • (2005) J. Immunol. , vol.175 , pp. 3025-3032
    • McGeachy, M.J.1    Stephens, L.A.2    Anderton, S.M.3
  • 66
    • 0036857530 scopus 로고    scopus 로고
    • The role of suppressor T cells in regulation of immune responses
    • McHugh R.S., and Shevach E.M. The role of suppressor T cells in regulation of immune responses. J. Allergy Clin. Immunol 110 (2002) 693-702
    • (2002) J. Allergy Clin. Immunol , vol.110 , pp. 693-702
    • McHugh, R.S.1    Shevach, E.M.2
  • 67
    • 0026542168 scopus 로고
    • Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering
    • Miller A., Lider O., Roberts A.B., Sporn M.B., and Weiner H.L. Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering. Proc. Natl. Acad. Sci. USA 89 (1992) 421-425
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 421-425
    • Miller, A.1    Lider, O.2    Roberts, A.B.3    Sporn, M.B.4    Weiner, H.L.5
  • 68
    • 0036197923 scopus 로고    scopus 로고
    • Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
    • Mizoguchi A., Mizoguchi E., Takedatsu H., Blumberg R.S., and Bhan A.K. Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 16 (2002) 219-230
    • (2002) Immunity , vol.16 , pp. 219-230
    • Mizoguchi, A.1    Mizoguchi, E.2    Takedatsu, H.3    Blumberg, R.S.4    Bhan, A.K.5
  • 69
    • 3242740010 scopus 로고    scopus 로고
    • Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies
    • Montero E., Nussbaum G., Kaye J.F., Perez R., Lage A., Ben-Nun A., and Cohen I.R. Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies. J. Autoimmun. 23 (2004) 1-7
    • (2004) J. Autoimmun. , vol.23 , pp. 1-7
    • Montero, E.1    Nussbaum, G.2    Kaye, J.F.3    Perez, R.4    Lage, A.5    Ben-Nun, A.6    Cohen, I.R.7
  • 70
    • 0021716470 scopus 로고
    • Experimental allergic encephalomyelitis in mice: adoptive transfer of disease is modulated by the presence of natural suppressor cells
    • Montgomery I.N., and Rauch H.C. Experimental allergic encephalomyelitis in mice: adoptive transfer of disease is modulated by the presence of natural suppressor cells. Neurochem. Res. 9 (1984) 1399-1406
    • (1984) Neurochem. Res. , vol.9 , pp. 1399-1406
    • Montgomery, I.N.1    Rauch, H.C.2
  • 71
    • 0028866978 scopus 로고
    • An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis
    • Nicholson L.B., Greer J.M., Sobel R.A., Lees M.B., and Kuchroo V.K. An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis. Immunity 3 (1995) 397-405
    • (1995) Immunity , vol.3 , pp. 397-405
    • Nicholson, L.B.1    Greer, J.M.2    Sobel, R.A.3    Lees, M.B.4    Kuchroo, V.K.5
  • 72
    • 0030797568 scopus 로고    scopus 로고
    • A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens
    • Nicholson L.B., Murtaza A., Hafler B.P., Sette A., and Kuchroo V.K. A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens. Proc. Natl. Acad. Sci. USA 94 (1997) 9279-9284
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9279-9284
    • Nicholson, L.B.1    Murtaza, A.2    Hafler, B.P.3    Sette, A.4    Kuchroo, V.K.5
  • 73
    • 34548734314 scopus 로고    scopus 로고
    • The inflamed central nervous system drives the activation and rapid proliferation of Foxp3+ regulatory T cells
    • O'Connor R.A., Malpass K.H., and Anderton S.M. The inflamed central nervous system drives the activation and rapid proliferation of Foxp3+ regulatory T cells. J. Immunol. 179 (2007) 958-966
    • (2007) J. Immunol. , vol.179 , pp. 958-966
    • O'Connor, R.A.1    Malpass, K.H.2    Anderton, S.M.3
  • 74
    • 33846527540 scopus 로고    scopus 로고
    • Regulatory T cell vaccination without autoantigen protects against experimental autoimmune encephalomyelitis
    • Ochoa-Reparaz J., Riccardi C., Rynda A., Jun S., Callis G., and Pascual D.W. Regulatory T cell vaccination without autoantigen protects against experimental autoimmune encephalomyelitis. J. Immunol. 178 (2007) 1791-1799
    • (2007) J. Immunol. , vol.178 , pp. 1791-1799
    • Ochoa-Reparaz, J.1    Riccardi, C.2    Rynda, A.3    Jun, S.4    Callis, G.5    Pascual, D.W.6
  • 75
    • 0032538918 scopus 로고    scopus 로고
    • Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis
    • Olivares-Villagomez D., Wang Y., and Lafaille J.J. Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. J. Exp. Med. 188 (1998) 1883-1894
    • (1998) J. Exp. Med. , vol.188 , pp. 1883-1894
    • Olivares-Villagomez, D.1    Wang, Y.2    Lafaille, J.J.3
  • 76
    • 28444491405 scopus 로고    scopus 로고
    • Enhanced FoxP3 expression and Treg cell function in pregnant and estrogen-treated mice
    • Polanczyk M.J., Hopke C., Huan J., Vandenbark A.A., and Offner H. Enhanced FoxP3 expression and Treg cell function in pregnant and estrogen-treated mice. J. Neuroimmunol. 170 (2005) 85-92
    • (2005) J. Neuroimmunol. , vol.170 , pp. 85-92
    • Polanczyk, M.J.1    Hopke, C.2    Huan, J.3    Vandenbark, A.A.4    Offner, H.5
  • 77
    • 0033739250 scopus 로고    scopus 로고
    • Detection of autoreactive T cells in H-2u mice using peptide-MHC multimers
    • Radu C.G., Anderton S.M., Firan M., Wraith D.C., and Ward E.S. Detection of autoreactive T cells in H-2u mice using peptide-MHC multimers. Int. Immunol. 12 (2000) 1553-1560
    • (2000) Int. Immunol. , vol.12 , pp. 1553-1560
    • Radu, C.G.1    Anderton, S.M.2    Firan, M.3    Wraith, D.C.4    Ward, E.S.5
  • 78
    • 0037438615 scopus 로고    scopus 로고
    • Detection of autoreactive myelin proteolipid protein 139-151-specific T cells by using MHC II (IAs) tetramers
    • Reddy J., Bettelli E., Nicholson L., Waldner H., Jang M.H., Wucherpfennig K.W., and Kuchroo V.K. Detection of autoreactive myelin proteolipid protein 139-151-specific T cells by using MHC II (IAs) tetramers. J. Immunol. 170 (2003) 870-877
    • (2003) J. Immunol. , vol.170 , pp. 870-877
    • Reddy, J.1    Bettelli, E.2    Nicholson, L.3    Waldner, H.4    Jang, M.H.5    Wucherpfennig, K.W.6    Kuchroo, V.K.7
  • 80
    • 27144480654 scopus 로고    scopus 로고
    • Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis
    • Reddy J., Waldner H., Zhang X., Illes Z., Wucherpfennig K.W., Sobel R.A., and Kuchroo V.K. Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis. J. Immunol. 175 (2005) 5591-5595
    • (2005) J. Immunol. , vol.175 , pp. 5591-5595
    • Reddy, J.1    Waldner, H.2    Zhang, X.3    Illes, Z.4    Wucherpfennig, K.W.5    Sobel, R.A.6    Kuchroo, V.K.7
  • 81
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 6 (2005) 345-352
    • (2005) Nat. Immunol. , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 82
    • 0021997185 scopus 로고
    • Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
    • Sakaguchi S., Fukuma K., Kuribayashi K., and Masuda T. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J. Exp. Med. 161 (1985) 72-87
    • (1985) J. Exp. Med. , vol.161 , pp. 72-87
    • Sakaguchi, S.1    Fukuma, K.2    Kuribayashi, K.3    Masuda, T.4
  • 83
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S., Sakaguchi N., Asano M., Itoh M., and Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155 (1995) 1151-1164
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 84
    • 0023050015 scopus 로고
    • Role of suppressor T cells in regulating passively induced experimental allergic encephalomyelitis
    • Sedgewick J.D. Role of suppressor T cells in regulating passively induced experimental allergic encephalomyelitis. J. Immunol. 137 (1986) 1407
    • (1986) J. Immunol. , vol.137 , pp. 1407
    • Sedgewick, J.D.1
  • 85
    • 0023949135 scopus 로고
    • Long-term depletion of CD8+ T cells in vivo in the rat: no observed role for CD8+ (cytotoxic/suppressor) cells in the immunoregulation of experimental allergic encephalomyelitis
    • Sedgwick J.D. Long-term depletion of CD8+ T cells in vivo in the rat: no observed role for CD8+ (cytotoxic/suppressor) cells in the immunoregulation of experimental allergic encephalomyelitis. Eur. J. Immunol. 18 (1988) 495-502
    • (1988) Eur. J. Immunol. , vol.18 , pp. 495-502
    • Sedgwick, J.D.1
  • 86
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage
    • Steinman L. A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage. Nat. Med. 13 (2007) 139-145
    • (2007) Nat. Med. , vol.13 , pp. 139-145
    • Steinman, L.1
  • 87
    • 33746918744 scopus 로고    scopus 로고
    • Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells"
    • Stephens L.A., and Anderton S.M. Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells". J. Immunol. 177 (2006) 2036-2037
    • (2006) J. Immunol. , vol.177 , pp. 2036-2037
    • Stephens, L.A.1    Anderton, S.M.2
  • 88
    • 28444444122 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity
    • Stephens L.A., Gray D., and Anderton S.M. CD4+CD25+ regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity. Proc. Natl. Acad. Sci. USA 102 (2005) 17418-17423
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17418-17423
    • Stephens, L.A.1    Gray, D.2    Anderton, S.M.3
  • 89
    • 0031939403 scopus 로고    scopus 로고
    • CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
    • Suri-Payer E., Amar A.Z., Thornton A.M., and Shevach E.M. CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol. 160 (1998) 1212-1218
    • (1998) J. Immunol. , vol.160 , pp. 1212-1218
    • Suri-Payer, E.1    Amar, A.Z.2    Thornton, A.M.3    Shevach, E.M.4
  • 90
    • 0016818290 scopus 로고
    • Suppressor cell control of unresponsiveness to experimental allergic encephalomyelitis
    • Swierkosz J.E., and Swanborg R.H. Suppressor cell control of unresponsiveness to experimental allergic encephalomyelitis. J. Immunol. 115 (1975) 631-633
    • (1975) J. Immunol. , vol.115 , pp. 631-633
    • Swierkosz, J.E.1    Swanborg, R.H.2
  • 91
    • 0342812444 scopus 로고
    • Aquired resistance to experimental allergic encephalomyelitis
    • Szvet-Moldavskaya I.A., and Svet-Moldavsky G.J. Aquired resistance to experimental allergic encephalomyelitis. Nature 181 (1958) 1536-1537
    • (1958) Nature , vol.181 , pp. 1536-1537
    • Szvet-Moldavskaya, I.A.1    Svet-Moldavsky, G.J.2
  • 92
    • 0020049299 scopus 로고
    • Transfer of allergic encephalomyelitis with spleen cells from donors sensitized with myelin basic protein in incomplete freunds adjuvant
    • Tadashi N., Richert J.R., Driscoll B.F., Kies M.W., and Alvord E.C. Transfer of allergic encephalomyelitis with spleen cells from donors sensitized with myelin basic protein in incomplete freunds adjuvant. J. Immunol. 128 (1982) 932-934
    • (1982) J. Immunol. , vol.128 , pp. 932-934
    • Tadashi, N.1    Richert, J.R.2    Driscoll, B.F.3    Kies, M.W.4    Alvord, E.C.5
  • 95
    • 0035399985 scopus 로고    scopus 로고
    • Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • Thorstenson K.M., and Khoruts A. Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J. Immunol. 167 (2001) 188-195
    • (2001) J. Immunol. , vol.167 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 99
    • 4444300314 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid
    • Van Amelsfort J.M.R., Jacobs K.M.G., Bijlsma J.W.J., Lafeber F.P.J.G., and Taams L.S. CD4+CD25+ regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid. Arthritis Rheum. 50 (2004) 2775-2785
    • (2004) Arthritis Rheum. , vol.50 , pp. 2775-2785
    • Van Amelsfort, J.M.R.1    Jacobs, K.M.G.2    Bijlsma, J.W.J.3    Lafeber, F.P.J.G.4    Taams, L.S.5
  • 100
    • 33744904725 scopus 로고    scopus 로고
    • Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression
    • Venken K., Hellings N., Hensen K., Rummens J.L., Medaer R., D'Hooghe M.B., Dubois B., Raus J., and Stinissen P. Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression. J. Neurosci. Res. 83 (2006) 1432-1446
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1432-1446
    • Venken, K.1    Hellings, N.2    Hensen, K.3    Rummens, J.L.4    Medaer, R.5    D'Hooghe, M.B.6    Dubois, B.7    Raus, J.8    Stinissen, P.9
  • 101
    • 18244391173 scopus 로고    scopus 로고
    • T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity
    • Verhoef A., Alexander C., Kay A.B., and Larche M. T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity. PLoS Med. 2 (2005) e78
    • (2005) PLoS Med. , vol.2
    • Verhoef, A.1    Alexander, C.2    Kay, A.B.3    Larche, M.4
  • 102
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
    • Viglietta V., Baecher-Allan C., Weiner H.L., and Hafler D.A. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J. Exp. Med. 199 (2004) 971-979
    • (2004) J. Exp. Med. , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 103
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat. Immunol. 6 (2005) 338-344
    • (2005) Nat. Immunol. , vol.6 , pp. 338-344
    • von Boehmer, H.1
  • 104
    • 33746342782 scopus 로고    scopus 로고
    • Infectious tolerance and the long-term acceptance of transplanted tissue
    • Waldmann H., Adams E., Fairchild P.J., and Cobbold S. Infectious tolerance and the long-term acceptance of transplanted tissue. Immunol. Rev. 212 (2006) 301-313
    • (2006) Immunol. Rev. , vol.212 , pp. 301-313
    • Waldmann, H.1    Adams, E.2    Fairchild, P.J.3    Cobbold, S.4
  • 105
    • 0022597552 scopus 로고
    • Immunoregulation of passively induced allergic encephalomyelitis
    • Willenborg D.O., Sjollema P., and Danta G. Immunoregulation of passively induced allergic encephalomyelitis. J. Immunol. 136 (1986) 1676-1679
    • (1986) J. Immunol. , vol.136 , pp. 1676-1679
    • Willenborg, D.O.1    Sjollema, P.2    Danta, G.3
  • 106
    • 0030456897 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice
    • Wolf S.D., Dittel B.N., Hardardottir F., and Janeway Jr. C.A. Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J. Exp. Med. 184 (1996) 2271-2278
    • (1996) J. Exp. Med. , vol.184 , pp. 2271-2278
    • Wolf, S.D.1    Dittel, B.N.2    Hardardottir, F.3    Janeway Jr., C.A.4
  • 107
    • 0024325672 scopus 로고
    • Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy
    • Wraith D.C., Smilek D.E., Mitchell D.J., Steinman L., and McDevitt H.O. Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell 59 (1989) 247-255
    • (1989) Cell , vol.59 , pp. 247-255
    • Wraith, D.C.1    Smilek, D.E.2    Mitchell, D.J.3    Steinman, L.4    McDevitt, H.O.5
  • 108
    • 0026463910 scopus 로고
    • Cross-reactive antigen recognition by an encephalitogenic T cell receptor. Implications for T cell biology and autoimmunity
    • Wraith D.C., Bruun B., and Fairchild P.J. Cross-reactive antigen recognition by an encephalitogenic T cell receptor. Implications for T cell biology and autoimmunity. J. Immunol. 149 (1992) 3765-3770
    • (1992) J. Immunol. , vol.149 , pp. 3765-3770
    • Wraith, D.C.1    Bruun, B.2    Fairchild, P.J.3
  • 110
    • 33746918744 scopus 로고    scopus 로고
    • Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells"
    • Zelenay S., and Demengeot J. Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells". J. Immunol. 177 (2006) 2036-a-2037
    • (2006) J. Immunol. , vol.177
    • Zelenay, S.1    Demengeot, J.2
  • 112
    • 33645225611 scopus 로고    scopus 로고
    • Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells
    • Zhang X., Reddy J., Ochi H., Frenkel D., Kuchroo V.K., and Weiner H.L. Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells. Int. Immunol. 18 (2006) 495-503
    • (2006) Int. Immunol. , vol.18 , pp. 495-503
    • Zhang, X.1    Reddy, J.2    Ochi, H.3    Frenkel, D.4    Kuchroo, V.K.5    Weiner, H.L.6


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