메뉴 건너뛰기




Volumn 177, Issue 3, 2006, Pages 1552-1560

Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells

Author keywords

[No Author keywords available]

Indexed keywords

PERTUSSIS TOXIN; TRANSCRIPTION FACTOR FOXP3;

EID: 33746214834     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.3.1552     Document Type: Article
Times cited : (54)

References (73)
  • 1
    • 0021323983 scopus 로고
    • Elicitation of experimental allergic encephalomyelitis (EAE) in mice with the aid of pertussigen
    • Munoz, J. J., C. C. Bernard, and I. R. Mackay. 1984. Elicitation of experimental allergic encephalomyelitis (EAE) in mice with the aid of pertussigen. Cell. Immunol. 83: 92-100.
    • (1984) Cell. Immunol. , vol.83 , pp. 92-100
    • Munoz, J.J.1    Bernard, C.C.2    Mackay, I.R.3
  • 2
    • 0020001747 scopus 로고
    • Development of acute autoimmune encephalomyelitis in mice: Factors regulating the effector phase of the disease
    • Linthicum, D. S. 1982. Development of acute autoimmune encephalomyelitis in mice: factors regulating the effector phase of the disease. Immunobiology 162: 211-220.
    • (1982) Immunobiology , vol.162 , pp. 211-220
    • Linthicum, D.S.1
  • 5
    • 0036341139 scopus 로고    scopus 로고
    • Pertussis toxin alters the innate and the adaptive immune responses in a pertussis-dependent model of autoimmunity
    • Agarwal, R. K., S. H. Sun, S. B. Su, C. C. Chan, and R. R. Caspi. 2002. Pertussis toxin alters the innate and the adaptive immune responses in a pertussis-dependent model of autoimmunity. J. Neuroimmunol. 129: 133-140.
    • (2002) J. Neuroimmunol. , vol.129 , pp. 133-140
    • Agarwal, R.K.1    Sun, S.H.2    Su, S.B.3    Chan, C.C.4    Caspi, R.R.5
  • 9
    • 0036857834 scopus 로고    scopus 로고
    • Bordetella pertussis toxin induces the release of inflammatory cytokines and dendritic cell activation in whole blood: Impaired responses in human newborns
    • Tonon, S., S. Goriely, E. Aksoy, O. Pradier, G. Del Giudice, E. Trannoy, F. Willems, M. Goldman, and D. De Wit. 2002. Bordetella pertussis toxin induces the release of inflammatory cytokines and dendritic cell activation in whole blood: impaired responses in human newborns. Eur. J. Immunol. 32: 3118-3125.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3118-3125
    • Tonon, S.1    Goriely, S.2    Aksoy, E.3    Pradier, O.4    Del Giudice, G.5    Trannoy, E.6    Willems, F.7    Goldman, M.8    De Wit, D.9
  • 11
    • 0023877979 scopus 로고
    • Lectin-like binding of pertussis toxin to a 165-kilodalton Chinese hamster ovary cell glycoprotein
    • Brennan, M. J., J. L. David, J. G. Kenimer, and C. R. Manclark. 1988. Lectin-like binding of pertussis toxin to a 165-kilodalton Chinese hamster ovary cell glycoprotein. J. Biol. Chem. 263: 4895-4899.
    • (1988) J. Biol. Chem. , vol.263 , pp. 4895-4899
    • Brennan, M.J.1    David, J.L.2    Kenimer, J.G.3    Manclark, C.R.4
  • 12
    • 0023689178 scopus 로고
    • Receptor analogs and monoclonal antibodies that inhibit adherence of Bordetella pertussis to human ciliated respiratory epithelial cells
    • Tuomanen, E., H. Towbin, G. Rosenfelder, D. Braun, G. Larson, G. C. Hansson, and R. Hill. 1988. Receptor analogs and monoclonal antibodies that inhibit adherence of Bordetella pertussis to human ciliated respiratory epithelial cells. J. Exp. Med. 168: 267-277.
    • (1988) J. Exp. Med. , vol.168 , pp. 267-277
    • Tuomanen, E.1    Towbin, H.2    Rosenfelder, G.3    Braun, D.4    Larson, G.5    Hansson, G.C.6    Hill, R.7
  • 14
    • 0019990340 scopus 로고
    • Modulation by islet-activating protein of adenylate cyclase activity in C6 glioma cells
    • Katada, T., T. Amano, and M. Ui. 1982. Modulation by islet-activating protein of adenylate cyclase activity in C6 glioma cells. J. Biol. Chem. 257: 3739-3746.
    • (1982) J. Biol. Chem. , vol.257 , pp. 3739-3746
    • Katada, T.1    Amano, T.2    Ui, M.3
  • 15
    • 0020137319 scopus 로고
    • Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein
    • Katada, T., and M. Ui. 1982. Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein. Proc. Natl. Acad. Sci. USA 79: 3129-3133.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 3129-3133
    • Katada, T.1    Ui, M.2
  • 16
    • 0035076244 scopus 로고    scopus 로고
    • Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin
    • Mielċarek, N., E. H. Hornquist, B. R. Johansson, C. Locht, S. N. Abraham, and J. Holmgren. 2001. Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin. Cell Microbiol. 3: 181-188.
    • (2001) Cell Microbiol. , vol.3 , pp. 181-188
    • Mielcarek, N.1    Hornquist, E.H.2    Johansson, B.R.3    Locht, C.4    Abraham, S.N.5    Holmgren, J.6
  • 18
    • 0034193331 scopus 로고    scopus 로고
    • Primary role for Gi protein signaling in the regulation of interleukin 12 production and the induction of T helper cell type 1 responses
    • He, J., S. Gurunathan, A. Iwasaki, B. Ash-Shaheed, and B. L. Kelsall. 2000. Primary role for Gi protein signaling in the regulation of interleukin 12 production and the induction of T helper cell type 1 responses. J. Exp. Med. 191: 1605-1610.
    • (2000) J. Exp. Med. , vol.191 , pp. 1605-1610
    • He, J.1    Gurunathan, S.2    Iwasaki, A.3    Ash-Shaheed, B.4    Kelsall, B.L.5
  • 19
    • 0031920860 scopus 로고    scopus 로고
    • Pertussis toxin potentiates Th1 and Th2 responses to co-injected antigen: Adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28
    • Ryan, M., L. McCarthy, R. Rappuoli, B. P. Mahon, and K. H. Mills. 1998. Pertussis toxin potentiates Th1 and Th2 responses to co-injected antigen: adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28. Int. Immunol. 10: 651-662.
    • (1998) Int. Immunol. , vol.10 , pp. 651-662
    • Ryan, M.1    McCarthy, L.2    Rappuoli, R.3    Mahon, B.P.4    Mills, K.H.5
  • 20
    • 0033838435 scopus 로고    scopus 로고
    • The enhanced antigen-specific production of cytokines induced by pertussis toxin is due to clonal expansion of T cells and not to altered effector functions of long-term memory cells
    • Shive, C. L., H. Hofstetter, L. Arredondo, C. Shaw, and T. G. Forsthuber. 2000. The enhanced antigen-specific production of cytokines induced by pertussis toxin is due to clonal expansion of T cells and not to altered effector functions of long-term memory cells. Eur. J. Immunol. 30: 2422-2431.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2422-2431
    • Shive, C.L.1    Hofstetter, H.2    Arredondo, L.3    Shaw, C.4    Forsthuber, T.G.5
  • 21
    • 0036644294 scopus 로고    scopus 로고
    • Pertussis toxin modulates the immune response to neuroantigens injected in incomplete Freund's adjuvant: Induction of ThI cells and experimental autoimmune encephalomyelitis in the presence of high frequencies of Th2 cells
    • Hofstetter, H. H., C. L. Shive, and T. G. Forsthuber. 2002. Pertussis toxin modulates the immune response to neuroantigens injected in incomplete Freund's adjuvant: induction of ThI cells and experimental autoimmune encephalomyelitis in the presence of high frequencies of Th2 cells. J. Immunol. 169: 117-125.
    • (2002) J. Immunol. , vol.169 , pp. 117-125
    • Hofstetter, H.H.1    Shive, C.L.2    Forsthuber, T.G.3
  • 22
    • 0029094907 scopus 로고
    • Pertussis toxin inhibits migration of B and T lymphocytes into splenic white pulp cords
    • Cyster, J. G., and C. C. Goodnow. 1995. Pertussis toxin inhibits migration of B and T lymphocytes into splenic white pulp cords. J. Exp. Med. 182: 581-586.
    • (1995) J. Exp. Med. , vol.182 , pp. 581-586
    • Cyster, J.G.1    Goodnow, C.C.2
  • 23
    • 0036687120 scopus 로고    scopus 로고
    • Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis
    • Alt, C., M. Laschinger, and B. Engelhardt. 2002. Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis. Eur. J. Immunol. 32: 2133-2144.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2133-2144
    • Alt, C.1    Laschinger, M.2    Engelhardt, B.3
  • 24
    • 0020446988 scopus 로고
    • Acute experimental autoimmune encephalomyelitis in mice. 1. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitization and increased vascular permeability of the central nervous system
    • Linthicum, D. S., J. J. Munoz, and A. Blaskett. 1982. Acute experimental autoimmune encephalomyelitis in mice. 1. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitization and increased vascular permeability of the central nervous system. Cell. Immunol. 73: 299-310.
    • (1982) Cell. Immunol. , vol.73 , pp. 299-310
    • Linthicum, D.S.1    Munoz, J.J.2    Blaskett, A.3
  • 25
    • 0019978357 scopus 로고
    • Acute autoimmune encephalomyelitis in mice. II. Susceptibility is controlled by the combination of H-2 and histamine sensitization genes
    • Linthicum, D. S., and J. A. Frelinger. 1982. Acute autoimmune encephalomyelitis in mice. II. Susceptibility is controlled by the combination of H-2 and histamine sensitization genes. J. Exp. Med. 156: 31-40.
    • (1982) J. Exp. Med. , vol.156 , pp. 31-40
    • Linthicum, D.S.1    Frelinger, J.A.2
  • 26
    • 17544401216 scopus 로고    scopus 로고
    • Permeabilization in a cerebral endothelial barrier model by pertussis toxin involves the PKC effector pathway and is abolished by elevated levels of cAMP
    • Bruckener, K. E., A. el Baya, H. J. Galla, and M. A. Schmidt. 2003. Permeabilization in a cerebral endothelial barrier model by pertussis toxin involves the PKC effector pathway and is abolished by elevated levels of cAMP. J. Cell Sci. 116: 1837-1846.
    • (2003) J. Cell Sci. , vol.116 , pp. 1837-1846
    • Bruckener, K.E.1    El Baya, A.2    Galla, H.J.3    Schmidt, M.A.4
  • 28
    • 19544363581 scopus 로고    scopus 로고
    • PTX cruiser: Driving autoimmunity via TLR4
    • Racke, M. K., W. Hu, and A. E. Lovett-Racke. 2005. PTX cruiser: driving autoimmunity via TLR4. Trends Immunol. 26: 289-291.
    • (2005) Trends Immunol. , vol.26 , pp. 289-291
    • Racke, M.K.1    Hu, W.2    Lovett-Racke, A.E.3
  • 29
    • 0025885799 scopus 로고
    • Pertussis toxin prevents the induction of peripheral T cell anergy and enhances the T cell response to an encephalitogenic peptide of myelin basic protein
    • Kamradt, T., P. D. Soloway, D. L. Perkins, and M. L. Gefter. 1991. Pertussis toxin prevents the induction of peripheral T cell anergy and enhances the T cell response to an encephalitogenic peptide of myelin basic protein. J. Immunol. 147: 3296-3302.
    • (1991) J. Immunol. , vol.147 , pp. 3296-3302
    • Kamradt, T.1    Soloway, P.D.2    Perkins, D.L.3    Gefter, M.L.4
  • 30
    • 2442484053 scopus 로고    scopus 로고
    • + regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • + regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22:531-562.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 33
    • 0036838536 scopus 로고    scopus 로고
    • + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. 169: 4712-4716.
    • (2002) J. Immunol. , vol.169 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 38
    • 0041467655 scopus 로고    scopus 로고
    • Cell-surface bound pertussis toxin induces polyclonal T cell responses with high levels of interferon-γ in the absence of interleukin-12
    • Wakatsuki, A., P. Borrow, K. Rigley, and P. C. Beverley. 2003. Cell-surface bound pertussis toxin induces polyclonal T cell responses with high levels of interferon-γ in the absence of interleukin-12. Eur. J. Immunol. 33: 1859-1868.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1859-1868
    • Wakatsuki, A.1    Borrow, P.2    Rigley, K.3    Beverley, P.C.4
  • 41
    • 28444444122 scopus 로고    scopus 로고
    • + regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity
    • + regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity. Proc. Natl. Acad. Sci. USA 102: 17418-17423.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17418-17423
    • Stephens, L.A.1    Gray, D.2    Anderton, S.M.3
  • 42
    • 0037100384 scopus 로고    scopus 로고
    • Modulation of Fas-dependent apoptosis: A dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells
    • Banz, A., C. Pontoux, and M. Papiernik. 2002. Modulation of Fas-dependent apoptosis: a dynamic process controlling both the persistence and death of CD4 regulatory T cells and effector T cells. J. Immunol. 169: 750-757.
    • (2002) J. Immunol. , vol.169 , pp. 750-757
    • Banz, A.1    Pontoux, C.2    Papiernik, M.3
  • 49
    • 27544446622 scopus 로고    scopus 로고
    • + regulatory T cells in the absence of interleukin 2 signaling
    • + regulatory T cells in the absence of interleukin 2 signaling. Nat. Immunol. 6: 1152-1159.
    • (2005) Nat. Immunol. , vol.6 , pp. 1152-1159
    • D'Cruz, L.M.1    Klein, L.2
  • 50
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot, J. D., J. P. Rasmussen, M. A. Gavin, and A. Y. Rudensky. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6: 1142-1151.
    • (2005) Nat. Immunol. , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 51
    • 0023140087 scopus 로고
    • Stimulation of specific GTP binding and hydrolysis activities in lymphocyte membrane by interleukin-2
    • Evans, S. W., S. K. Beckner, and W. L. Farrar. 1987. Stimulation of specific GTP binding and hydrolysis activities in lymphocyte membrane by interleukin-2. Nature 325: 166-168.
    • (1987) Nature , vol.325 , pp. 166-168
    • Evans, S.W.1    Beckner, S.K.2    Farrar, W.L.3
  • 52
    • 0037270978 scopus 로고    scopus 로고
    • Hepatic T cells and liver tolerance
    • Crispe, I. N. 2003. Hepatic T cells and liver tolerance. Nat. Rev. Immunol. 3: 51-62.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 51-62
    • Crispe, I.N.1
  • 57
    • 0036721772 scopus 로고    scopus 로고
    • + splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7
    • + splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7. J. Immunol. 169: 2461-2465.
    • (2002) J. Immunol. , vol.169 , pp. 2461-2465
    • Szanya, V.1    Ermann, J.2    Taylor, C.3    Holness, C.4    Fathman, C.G.5
  • 58
    • 0035399951 scopus 로고    scopus 로고
    • Pertussis toxin inhibits induction of tissue-specific autoimmune disease by disrupting G protein-coupled signals
    • Su, S. B., P. B. Silver, M. Zhang, C. C. Chan, and R. R. Caspi. 2001. Pertussis toxin inhibits induction of tissue-specific autoimmune disease by disrupting G protein-coupled signals. J. Immunol. 167: 250-256.
    • (2001) J. Immunol. , vol.167 , pp. 250-256
    • Su, S.B.1    Silver, P.B.2    Zhang, M.3    Chan, C.C.4    Caspi, R.R.5
  • 59
    • 0037111201 scopus 로고    scopus 로고
    • G protein-coupled chemokine receptors induce both survival and apoptotic signaling pathways
    • Vlahakis, S. R., A. Villasis-Keever, T. Gomez, M. Vanegas, N. Vlahakis, and C. V. Paya. 2002. G protein-coupled chemokine receptors induce both survival and apoptotic signaling pathways. J. Immunol. 169: 5546-5554.
    • (2002) J. Immunol. , vol.169 , pp. 5546-5554
    • Vlahakis, S.R.1    Villasis-Keever, A.2    Gomez, T.3    Vanegas, M.4    Vlahakis, N.5    Paya, C.V.6
  • 60
    • 2542428442 scopus 로고    scopus 로고
    • Chemokines in innate and adaptive host defense: Basic chemokinese grammar for immune cells
    • Rot, A., and U. H. von Andrian. 2004. Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells. Annu. Rev. Immunol. 22: 891-928.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 891-928
    • Rot, A.1    Von Andrian, U.H.2
  • 61
    • 21844457949 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and its receptors: An autocrine and paracrine network
    • Rosen, H., and E. J. Goetzl. 2005. Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network. Nat. Rev. Immunol. 5: 560-570.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 560-570
    • Rosen, H.1    Goetzl, E.J.2
  • 64
    • 0031179652 scopus 로고    scopus 로고
    • Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis
    • Brabb, T., A. W. Goldrath, P. von Dassow, A. Paez, H. D. Liggitt, and J. Goverman. 1997. Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis. J. Immunol. 159: 497-507.
    • (1997) J. Immunol. , vol.159 , pp. 497-507
    • Brabb, T.1    Goldrath, A.W.2    Von Dassow, P.3    Paez, A.4    Liggitt, H.D.5    Goverman, J.6
  • 65
    • 0035217962 scopus 로고    scopus 로고
    • Modes of action of Freund's adjuvants in experimental models of autoimmune diseases
    • Billiau, A., and P. Matthys. 2001. Modes of action of Freund's adjuvants in experimental models of autoimmune diseases. J. Leukocyte Biol. 70: 849-860.
    • (2001) J. Leukocyte Biol. , vol.70 , pp. 849-860
    • Billiau, A.1    Matthys, P.2
  • 66
    • 2142821465 scopus 로고    scopus 로고
    • Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease
    • Waldner, H., M. Collins, and V. K. Kuchroo. 2004. Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease. J. Clin. Invest. 113: 990-997.
    • (2004) J. Clin. Invest. , vol.113 , pp. 990-997
    • Waldner, H.1    Collins, M.2    Kuchroo, V.K.3
  • 68
    • 0037450804 scopus 로고    scopus 로고
    • Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide
    • Caramalho, I., T. Lopes-Carvalho, D. Ostler, S. Zelenay, M. Haury, and J. Demengeot. 2003. Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide. J. Exp. Med. 197: 403-411.
    • (2003) J. Exp. Med. , vol.197 , pp. 403-411
    • Caramalho, I.1    Lopes-Carvalho, T.2    Ostler, D.3    Zelenay, S.4    Haury, M.5    Demengeot, J.6
  • 70
    • 0037436119 scopus 로고    scopus 로고
    • + T cell-mediated suppression by dendritic cells
    • + T cell-mediated suppression by dendritic cells. Science 299: 1033-1036.
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 71
    • 10344233176 scopus 로고    scopus 로고
    • Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells
    • Kubo, T., R. D. Hatton, J. Oliver, X. Liu, C. O. Elson, and C. T. Weaver. 2004. Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells. J. Immunol. 173: 7249-7258.
    • (2004) J. Immunol. , vol.173 , pp. 7249-7258
    • Kubo, T.1    Hatton, R.D.2    Oliver, J.3    Liu, X.4    Elson, C.O.5    Weaver, C.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.