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Volumn 35, Issue 21, 2007, Pages 7128-7139

Aminoglycoside binding to the HIV-1 RNA dimerization initiation site: Thermodynamics and effect on the kissing-loop to duplex conversion

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; APRAMYCIN; BACTERIAL RNA; HUMAN IMMUNODEFICIENCY VIRUS 1 RNA; LIVIDOMYCIN; NEAMINE; NEOMYCIN; PAROMOMYCIN; RIBOSTAMYCIN; RNA 16S; TOBRAMYCIN; UNCLASSIFIED DRUG;

EID: 37549003235     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm856     Document Type: Article
Times cited : (45)

References (55)
  • 1
    • 20444495201 scopus 로고    scopus 로고
    • Drugs targeting the ribosome
    • Hermann,T. (2005) Drugs targeting the ribosome. Curr. Opin. Struct. Biol., 15, 355-366.
    • (2005) Curr. Opin. Struct. Biol , vol.15 , pp. 355-366
    • Hermann, T.1
  • 2
    • 0142011647 scopus 로고    scopus 로고
    • Targeting RNA with small molecules
    • Tor,Y. (2003) Targeting RNA with small molecules. Chembiochem, 4, 998-1007.
    • (2003) Chembiochem , vol.4 , pp. 998-1007
    • Tor, Y.1
  • 3
    • 0142106950 scopus 로고    scopus 로고
    • RNA as a drug target: The case of aminoglycosides
    • Vicens,Q. and Westhof,E. (2003) RNA as a drug target: The case of aminoglycosides. Chembiochem, 4, 1018-1023.
    • (2003) Chembiochem , vol.4 , pp. 1018-1023
    • Vicens, Q.1    Westhof, E.2
  • 4
    • 0032554635 scopus 로고    scopus 로고
    • Binding of neomycin to the TAR element of HIV-1 RNA induces dissociation of Tat protein by an allosteric mechanism
    • Wang,S., Huber,P.W., Cui,M., Czarnik,A.W. and Mei,H.Y. (1998) Binding of neomycin to the TAR element of HIV-1 RNA induces dissociation of Tat protein by an allosteric mechanism. Biochemistry, 37, 5549-5557.
    • (1998) Biochemistry , vol.37 , pp. 5549-5557
    • Wang, S.1    Huber, P.W.2    Cui, M.3    Czarnik, A.W.4    Mei, H.Y.5
  • 5
    • 0027370433 scopus 로고
    • Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production
    • Zapp,M.L., Stern,S. and Green,M.R. (1993) Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production. Cell, 74, 969-978.
    • (1993) Cell , vol.74 , pp. 969-978
    • Zapp, M.L.1    Stern, S.2    Green, M.R.3
  • 6
    • 0029900161 scopus 로고    scopus 로고
    • Evidence that a kissing loop structure facilitates genomic RNA dimerisation in HIV-1
    • Haddrick,M., Lear,A.L., Cann,A.J. and Heaphy,S. (1996) Evidence that a kissing loop structure facilitates genomic RNA dimerisation in HIV-1. J. Mol. Biol., 259, 58-68.
    • (1996) J. Mol. Biol , vol.259 , pp. 58-68
    • Haddrick, M.1    Lear, A.L.2    Cann, A.J.3    Heaphy, S.4
  • 7
    • 0029861557 scopus 로고    scopus 로고
    • A dual role of the dimerization initiation site of HIV-1 in genomic RNA packaging and proviral DNA synthesis
    • Paillart,J.-C., Berthoux,L., Ottmann,M., Darlix,J.-L., Marquet,R., Ehresmann,C. and Ehresmann,B. (1996) A dual role of the dimerization initiation site of HIV-1 in genomic RNA packaging and proviral DNA synthesis. J. Virol., 70, 8348-8354.
    • (1996) J. Virol , vol.70 , pp. 8348-8354
    • Paillart, J.-C.1    Berthoux, L.2    Ottmann, M.3    Darlix, J.-L.4    Marquet, R.5    Ehresmann, C.6    Ehresmann, B.7
  • 8
    • 0035965239 scopus 로고    scopus 로고
    • The kissing hairpin sequence promotes recombination within the HIV-I 5′ leader region
    • Balakrishnan,M., Fay,P.J. and Bambara,R.A. (2001) The kissing hairpin sequence promotes recombination within the HIV-I 5′ leader region. J. Biol. Chem., 276, 36482-36492.
    • (2001) J. Biol. Chem , vol.276 , pp. 36482-36492
    • Balakrishnan, M.1    Fay, P.J.2    Bambara, R.A.3
  • 9
    • 21144446779 scopus 로고    scopus 로고
    • Identification of a major restriction in HIV-1 intersubtype recombination
    • Chin,M.P., Rhodes,T.D., Chen,J., Fu,W. and Hu,W.S. (2005) Identification of a major restriction in HIV-1 intersubtype recombination. Proc. Natl Acad. Sci. USA, 102, 9002-9007.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 9002-9007
    • Chin, M.P.1    Rhodes, T.D.2    Chen, J.3    Fu, W.4    Hu, W.S.5
  • 10
    • 0029796006 scopus 로고    scopus 로고
    • Role of the DIS hairpin in replication of human immunodeficiency virus type 1
    • Berkhout,B. and van Wamel,J.L. (1996) Role of the DIS hairpin in replication of human immunodeficiency virus type 1. J. Virol., 70, 6723-6732.
    • (1996) J. Virol , vol.70 , pp. 6723-6732
    • Berkhout, B.1    van Wamel, J.L.2
  • 11
    • 0034074812 scopus 로고    scopus 로고
    • Impact of human immunodeficiency virus type 1 RNA dimerization on viral infectivity and of stem-loop B on RNA dimerization and reverse transcription and dissociation of dimerization from packaging
    • Shen,N., Jette,L., Liang,C., Wainberg,M.A. and Laughrea,M. (2000) Impact of human immunodeficiency virus type 1 RNA dimerization on viral infectivity and of stem-loop B on RNA dimerization and reverse transcription and dissociation of dimerization from packaging. J. Virol., 74, 5729-5735.
    • (2000) J. Virol , vol.74 , pp. 5729-5735
    • Shen, N.1    Jette, L.2    Liang, C.3    Wainberg, M.A.4    Laughrea, M.5
  • 12
    • 0028027708 scopus 로고
    • A 19-nucleotide sequence upstream of the 5′ major splice donor site is part of the dimerization domain of human immunodeficiency virus 1 genomic RNA
    • Laughrea,M. and Jetté,L. (1994) A 19-nucleotide sequence upstream of the 5′ major splice donor site is part of the dimerization domain of human immunodeficiency virus 1 genomic RNA. Biochemistry, 33 13464-13474.
    • (1994) Biochemistry , vol.33 , pp. 13464-13474
    • Laughrea, M.1    Jetté, L.2
  • 14
  • 15
    • 0028239204 scopus 로고
    • Identification of the primary site of the human immunodeficiency virus type 1 RNA dimerization in vitro
    • Skripkin,E., Paillart,J.C., Marquet,R., Ehresmann,B. and Ehresmann,C. (1994) Identification of the primary site of the human immunodeficiency virus type 1 RNA dimerization in vitro. Proc. Natl Acad. Sci. USA, 91, 4945-4949.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 4945-4949
    • Skripkin, E.1    Paillart, J.C.2    Marquet, R.3    Ehresmann, B.4    Ehresmann, C.5
  • 16
    • 9444271764 scopus 로고    scopus 로고
    • Requirements for kissing-loop-mediated dimerization of human immunodeficiency virus RNA
    • Clever,J.L., Wong,M.L. and Parslow,T.G. (1996) Requirements for kissing-loop-mediated dimerization of human immunodeficiency virus RNA. J. Virol., 70, 5902-5908.
    • (1996) J. Virol , vol.70 , pp. 5902-5908
    • Clever, J.L.1    Wong, M.L.2    Parslow, T.G.3
  • 17
    • 0031552595 scopus 로고    scopus 로고
    • Non-canonical interactions in a kissing loop complex: The dimerization initiation site of HIV-1 genomic RNA
    • Paillart,J.C., Westhof,E., Ehresmann,C., Ehresmann,B. and Marquet,R. (1997) Non-canonical interactions in a kissing loop complex: The dimerization initiation site of HIV-1 genomic RNA. J. Mol. Biol., 270, 36-49.
    • (1997) J. Mol. Biol , vol.270 , pp. 36-49
    • Paillart, J.C.1    Westhof, E.2    Ehresmann, C.3    Ehresmann, B.4    Marquet, R.5
  • 18
    • 0030480326 scopus 로고    scopus 로고
    • NCP7 activates HIV-1 Lai RNA dimerization by converting a transient loop-loop complex into a stable dimer
    • Muriaux,D., Rocquigny,H.D., Roques,B.P. and Paoletti,J. (1996) NCP7 activates HIV-1 Lai RNA dimerization by converting a transient loop-loop complex into a stable dimer. J. Biol. Chem., 271, 33686-33692.
    • (1996) J. Biol. Chem , vol.271 , pp. 33686-33692
    • Muriaux, D.1    Rocquigny, H.D.2    Roques, B.P.3    Paoletti, J.4
  • 19
    • 0037126724 scopus 로고    scopus 로고
    • Mechanism of nucleocapsid protein catalyzed structural isomerization of the dimerization initiation site of HIV-1
    • Rist,M.J. and Marino,J.P. (2002) Mechanism of nucleocapsid protein catalyzed structural isomerization of the dimerization initiation site of HIV-1. Biochemistry, 41, 14762-14770.
    • (2002) Biochemistry , vol.41 , pp. 14762-14770
    • Rist, M.J.1    Marino, J.P.2
  • 20
    • 0033959583 scopus 로고    scopus 로고
    • Structural requirement for the two-step dimerization of human immunodeficiency virus type 1 genome
    • Takahashi,K.I., Baba,S., Chattopadhyay,P., Koyanagi,Y., Yamamoto,N., Takaku,H. and Kawai,G. (2000) Structural requirement for the two-step dimerization of human immunodeficiency virus type 1 genome. RNA, 6, 96-102.
    • (2000) RNA , vol.6 , pp. 96-102
    • Takahashi, K.I.1    Baba, S.2    Chattopadhyay, P.3    Koyanagi, Y.4    Yamamoto, N.5    Takaku, H.6    Kawai, G.7
  • 21
    • 0033571104 scopus 로고    scopus 로고
    • The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges
    • Ennifar,E., Yusupov,M., Walter,P., Marquet,R., Ehresmann,B., Ehresmann,C. and Dumas,P. (1999) The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges. Structure, 7, 1439-1449.
    • (1999) Structure , vol.7 , pp. 1439-1449
    • Ennifar, E.1    Yusupov, M.2    Walter, P.3    Marquet, R.4    Ehresmann, B.5    Ehresmann, C.6    Dumas, P.7
  • 22
    • 31344481887 scopus 로고    scopus 로고
    • Polymorphism of bulged-out residues in HIV-1 RNA DIS kissing complex and structure comparison with solution studies
    • Ennifar,E. and Dumas,P. (2006) Polymorphism of bulged-out residues in HIV-1 RNA DIS kissing complex and structure comparison with solution studies. J. Mol. Biol., 356, 771-782.
    • (2006) J. Mol. Biol , vol.356 , pp. 771-782
    • Ennifar, E.1    Dumas, P.2
  • 23
    • 0035184520 scopus 로고    scopus 로고
    • Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site
    • Ennifar,E., Walter,P., Ehresmann,B., Ehresmann,C. and Dumas,P. (2001) Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site. Nat. Struct. Biol., 8, 1064-1068.
    • (2001) Nat. Struct. Biol , vol.8 , pp. 1064-1068
    • Ennifar, E.1    Walter, P.2    Ehresmann, B.3    Ehresmann, C.4    Dumas, P.5
  • 24
    • 0037462818 scopus 로고    scopus 로고
    • HIV-1 RNA dimerization initiation site is structurally similar to the ribosomal A site and binds aminoglycoside antibiotics
    • Ennifar,E., Paillart,J.C., Marquet,R., Ehresmann,B., Ehresmann,C., Dumas,P. and Walter,P. (2003) HIV-1 RNA dimerization initiation site is structurally similar to the ribosomal A site and binds aminoglycoside antibiotics. J. Biol. Chem., 278, 2723-2730.
    • (2003) J. Biol. Chem , vol.278 , pp. 2723-2730
    • Ennifar, E.1    Paillart, J.C.2    Marquet, R.3    Ehresmann, B.4    Ehresmann, C.5    Dumas, P.6    Walter, P.7
  • 27
    • 0018141671 scopus 로고
    • Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes
    • Gonzalez,A., Jimenez,A., Vazquez,D., Davies,J.E. and Schindler,D. (1978) Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes. Biochim. Biophys. Acta, 521, 459-469.
    • (1978) Biochim. Biophys. Acta , vol.521 , pp. 459-469
    • Gonzalez, A.1    Jimenez, A.2    Vazquez, D.3    Davies, J.E.4    Schindler, D.5
  • 28
    • 0018717499 scopus 로고
    • Effects of apramycin, a novel aminoglycoside antibiotic on bacterial protein synthesis
    • Perzynski,S., Cannon,M., Cundliffe,E., Chahwala,S.B. and Davies,J. (1979) Effects of apramycin, a novel aminoglycoside antibiotic on bacterial protein synthesis. Eur. J. Biochem., 99, 623-628.
    • (1979) Eur. J. Biochem , vol.99 , pp. 623-628
    • Perzynski, S.1    Cannon, M.2    Cundliffe, E.3    Chahwala, S.B.4    Davies, J.5
  • 29
    • 0029905917 scopus 로고    scopus 로고
    • Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: Use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the HIV RNA rev responsive element
    • Park,W.K.C., Auer,M., Jaksche,H. and Wong,C.H. (1996) Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: Use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the HIV RNA rev responsive element. J. Am. Chem. Soc. 118, 10150-10155.
    • (1996) J. Am. Chem. Soc , vol.118 , pp. 10150-10155
    • Park, W.K.C.1    Auer, M.2    Jaksche, H.3    Wong, C.H.4
  • 30
    • 28844509141 scopus 로고    scopus 로고
    • Mechanism of hairpin-duplex conversion for the HIV-1 dimerization initiation site
    • Bernacchi,S., Ennifar,E., Toth,K., Walter,P., Langowski,J. and Dumas,P. (2005) Mechanism of hairpin-duplex conversion for the HIV-1 dimerization initiation site. J. Biol. Chem., 280, 40112-40121.
    • (2005) J. Biol. Chem , vol.280 , pp. 40112-40121
    • Bernacchi, S.1    Ennifar, E.2    Toth, K.3    Walter, P.4    Langowski, J.5    Dumas, P.6
  • 31
    • 0034886697 scopus 로고    scopus 로고
    • Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site
    • Vicens,Q. and Westhof,E. (2001) Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site. Structure Fold Des. 9, 647-658.
    • (2001) Structure Fold Des , vol.9 , pp. 647-658
    • Vicens, Q.1    Westhof, E.2
  • 32
    • 0000356656 scopus 로고
    • A graphic model building and refinement system for macromolecules
    • Jones,T.A. (1978) A graphic model building and refinement system for macromolecules. J. Appl. Crystallogr., 11, 268-272.
    • (1978) J. Appl. Crystallogr , vol.11 , pp. 268-272
    • Jones, T.A.1
  • 34
    • 14744271960 scopus 로고    scopus 로고
    • ITC in the post-genomic era...? Priceless
    • Velazquez Campoy,A. and Freire,E. (2005) ITC in the post-genomic era...? Priceless. Biophys. Chem., 115, 115-124.
    • (2005) Biophys. Chem , vol.115 , pp. 115-124
    • Velazquez Campoy, A.1    Freire, E.2
  • 35
    • 0037424612 scopus 로고    scopus 로고
    • Coupling of drug protonation to the specific binding of aminoglycosides to the A site of 16 S rRNA: Elucidation of the number of drug amino groups involved and their identities
    • Kaul,M., Barbieri,C.M., Kerrigan,J.E. and Pilch,D.S. (2003) Coupling of drug protonation to the specific binding of aminoglycosides to the A site of 16 S rRNA: Elucidation of the number of drug amino groups involved and their identities. J. Mol. Biol., 326, 1373-1387.
    • (2003) J. Mol. Biol , vol.326 , pp. 1373-1387
    • Kaul, M.1    Barbieri, C.M.2    Kerrigan, J.E.3    Pilch, D.S.4
  • 36
    • 0031670461 scopus 로고    scopus 로고
    • Enthalpy and heat capacity changes for the proton dissociation of various buffer components in 0.1 M potassium chloride
    • Fukada,H. and Takahashi,K. (1998) Enthalpy and heat capacity changes for the proton dissociation of various buffer components in 0.1 M potassium chloride. Proteins, 33, 159-166.
    • (1998) Proteins , vol.33 , pp. 159-166
    • Fukada, H.1    Takahashi, K.2
  • 37
    • 0037129948 scopus 로고    scopus 로고
    • Thermodynamics of aminoglycoside-rRNA recognition: The binding of neomycin-class aminoglycosides to the A site of 16S rRNA
    • Kaul,M. and Pilch,D.S. (2002) Thermodynamics of aminoglycoside-rRNA recognition: The binding of neomycin-class aminoglycosides to the A site of 16S rRNA. Biochemistry, 41, 7695-7706.
    • (2002) Biochemistry , vol.41 , pp. 7695-7706
    • Kaul, M.1    Pilch, D.S.2
  • 38
    • 33947405176 scopus 로고    scopus 로고
    • Fluorescent HIV-1 dimerization initiation site: Design, properties, and use for ligand discovery
    • Tam,V.K., Kwong,D. and Tor,Y. (2007) Fluorescent HIV-1 dimerization initiation site: Design, properties, and use for ligand discovery. J. Am. Chem. Soc., 129, 3257-3266.
    • (2007) J. Am. Chem. Soc , vol.129 , pp. 3257-3266
    • Tam, V.K.1    Kwong, D.2    Tor, Y.3
  • 40
    • 0034704217 scopus 로고    scopus 로고
    • The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit
    • Brodersen,D.E., Clemons,W.M.Jr, Carter,A.P., Morgan-Warren,R.J., Wimberly,B.T. and Ramakrishnan,V. (2000) The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell, 103, 1143-1154.
    • (2000) Cell , vol.103 , pp. 1143-1154
    • Brodersen, D.E.1    Clemons Jr, W.M.2    Carter, A.P.3    Morgan-Warren, R.J.4    Wimberly, B.T.5    Ramakrishnan, V.6
  • 41
    • 12344275674 scopus 로고    scopus 로고
    • Defining the basis for the specificity of aminoglycoside-rRNA recognition: A comparative study of drug binding to the A sites of Escherichia coli and human rRNA
    • Kaul,M., Barbieri,C.M. and Pilch,D.S. (2005) Defining the basis for the specificity of aminoglycoside-rRNA recognition: A comparative study of drug binding to the A sites of Escherichia coli and human rRNA. J. Mol. Biol., 346, 119-134.
    • (2005) J. Mol. Biol , vol.346 , pp. 119-134
    • Kaul, M.1    Barbieri, C.M.2    Pilch, D.S.3
  • 42
    • 31944443056 scopus 로고    scopus 로고
    • Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity
    • Kaul,M., Barbieri,C.M. and Pilch,D.S. (2006) Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity. J. Am. Chem. Soc., 128, 1261-1271.
    • (2006) J. Am. Chem. Soc , vol.128 , pp. 1261-1271
    • Kaul, M.1    Barbieri, C.M.2    Pilch, D.S.3
  • 44
    • 0032126750 scopus 로고    scopus 로고
    • Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA
    • Wong,C.H., Hendrix,M., Priestley,E.S. and Greenberg,W.A. (1998) Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA. Chem. Biol., 5, 397-406.
    • (1998) Chem. Biol , vol.5 , pp. 397-406
    • Wong, C.H.1    Hendrix, M.2    Priestley, E.S.3    Greenberg, W.A.4
  • 46
    • 0032507263 scopus 로고    scopus 로고
    • Probing the specificity of aminoglycoside-ribosomal RNA interactions with designed synthetic analogs
    • Alper,P.B., Hendrix,M., Sears,P. and Wong,C.-H. (1998) Probing the specificity of aminoglycoside-ribosomal RNA interactions with designed synthetic analogs. J. Am. Chem. Soc., 120, 1965-1978.
    • (1998) J. Am. Chem. Soc , vol.120 , pp. 1965-1978
    • Alper, P.B.1    Hendrix, M.2    Sears, P.3    Wong, C.-H.4
  • 47
    • 0037138652 scopus 로고    scopus 로고
    • Binding of aminoglycoside antibiotics to the small ribosomal subunit: A continuum electrostatics investigation
    • Ma,C., Baker,N.A., Joseph,S. and McCammon,J.A. (2002) Binding of aminoglycoside antibiotics to the small ribosomal subunit: A continuum electrostatics investigation. J. Am. Chem. Soc., 124, 1438-1442.
    • (2002) J. Am. Chem. Soc , vol.124 , pp. 1438-1442
    • Ma, C.1    Baker, N.A.2    Joseph, S.3    McCammon, J.A.4
  • 48
    • 0024804759 scopus 로고
    • Absorbance melting curves of RNA
    • Puglisi,J.D. and Tinoco,I.Jr. (1989) Absorbance melting curves of RNA. Methods Enzymol., 180, 304-325.
    • (1989) Methods Enzymol , vol.180 , pp. 304-325
    • Puglisi, J.D.1    Tinoco Jr., I.2
  • 49
    • 0030019828 scopus 로고    scopus 로고
    • Kissing-loop model of HIV-1 genome dimerization: HIV-1 RNA can assume alternative dimeric forms, and all sequences upstream or downstream of hairpin 248-271 are dispensable for dimer formation
    • Laughrea,M. and Jetté,L. (1996) Kissing-loop model of HIV-1 genome dimerization: HIV-1 RNA can assume alternative dimeric forms, and all sequences upstream or downstream of hairpin 248-271 are dispensable for dimer formation. Biochemistry, 35, 1589-1598.
    • (1996) Biochemistry , vol.35 , pp. 1589-1598
    • Laughrea, M.1    Jetté, L.2
  • 52
    • 0034071970 scopus 로고    scopus 로고
    • The HIV-1(Lai) RNA dimerization. Thermodynamic parameters associated with the transition from the kissing complex to the extended dimer
    • Theilleux-Delalande,V., Girard,F., Huynh-Dinh,T., Lancelot,G. and Paoletti,J. (2000) The HIV-1(Lai) RNA dimerization. Thermodynamic parameters associated with the transition from the kissing complex to the extended dimer. Eur. J. Biochem., 267, 2711-2719.
    • (2000) Eur. J. Biochem , vol.267 , pp. 2711-2719
    • Theilleux-Delalande, V.1    Girard, F.2    Huynh-Dinh, T.3    Lancelot, G.4    Paoletti, J.5
  • 54
    • 0346341029 scopus 로고    scopus 로고
    • TectoRNA and 'kissing-loop' RNA: Atomic force microscopy of self-assembling RNA structures
    • Hansma,H.G., Oroudjev,E., Baudrey,S. and Jaeger,L. (2003) TectoRNA and 'kissing-loop' RNA: Atomic force microscopy of self-assembling RNA structures. J. Microsc., 212, 273-279.
    • (2003) J. Microsc , vol.212 , pp. 273-279
    • Hansma, H.G.1    Oroudjev, E.2    Baudrey, S.3    Jaeger, L.4
  • 55
    • 0042631224 scopus 로고    scopus 로고
    • RNA LEGO: Magnesium-dependent formation of specific RNA assemblies through kissing interactions
    • Horiya,S., Li,X., Kawai,G., Saito,R., Katoh,A., Kobayashi,K. and Harada,K. (2003) RNA LEGO: Magnesium-dependent formation of specific RNA assemblies through kissing interactions. Chem. Biol., 10, 645-654.
    • (2003) Chem. Biol , vol.10 , pp. 645-654
    • Horiya, S.1    Li, X.2    Kawai, G.3    Saito, R.4    Katoh, A.5    Kobayashi, K.6    Harada, K.7


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