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Volumn 259, Issue , 2004, Pages 269-284

Histone deacetylase inhibitors: Development as cancer therapy

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE;

EID: 2942724589     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (79)

References (51)
  • 1
    • 0036746906 scopus 로고    scopus 로고
    • Antineoplastic action of 5-aza-2′-deoxycytidine and phenylbutyrate on human lung carcinoma cells
    • Boivin AJ, Momparler LF, Hurtubise A, Momparler RL 2002 Antineoplastic action of 5-aza-2′-deoxycytidine and phenylbutyrate on human lung carcinoma cells. Anticancer Drugs 13:869-874
    • (2002) Anticancer Drugs , vol.13 , pp. 869-874
    • Boivin, A.J.1    Momparler, L.F.2    Hurtubise, A.3    Momparler, R.L.4
  • 2
    • 0037468554 scopus 로고    scopus 로고
    • Development of potential antitumor agents. Synthesis and biological evaluation of a new set of sulfonamide derivatives as histone deacetylase inhibitors
    • Bouchain G, Leit S, Frechette S et al 2003 Development of potential antitumor agents. Synthesis and biological evaluation of a new set of sulfonamide derivatives as histone deacetylase inhibitors. J Med Chem 46:820-830
    • (2003) J Med Chem , vol.46 , pp. 820-830
    • Bouchain, G.1    Leit, S.2    Frechette, S.3
  • 3
    • 0037015071 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin
    • USA
    • Butler LM, Zhou X, Xu W-S et al 2002 The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin. Proc Natl Acad Sci USA 99:11700-11705
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 11700-11705
    • Butler, L.M.1    Zhou, X.2    Xu, W.-S.3
  • 4
    • 0000403664 scopus 로고    scopus 로고
    • Phenylbutyrate (PB) for refractory solid tumors: Phase I clinical and pharmacologic evaluation of intravenous and oral PB
    • Carducci M, Bowling MK, Eisenberger MA et al 1997 Phenylbutyrate (PB) for refractory solid tumors: phase I clinical and pharmacologic evaluation of intravenous and oral PB. Anticancer Res 17:3972-3973
    • (1997) Anticancer Res , vol.17 , pp. 3972-3973
    • Carducci, M.1    Bowling, M.K.2    Eisenberger, M.A.3
  • 5
    • 0033053292 scopus 로고    scopus 로고
    • Phase II study of phenylacetate in patients with recurrent malignant glioma: A North American Brain Tumor Consortium report
    • Chang SM, Kuhn JG, Robins HI et al 1999 Phase II study of phenylacetate in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report. J Clin Oncol 17:984-990
    • (1999) J Clin Oncol , vol.17 , pp. 984-990
    • Chang, S.M.1    Kuhn, J.G.2    Robins, H.I.3
  • 6
    • 18644362147 scopus 로고    scopus 로고
    • Succinimide hydroxamic acids as potent inhibitors of histone deacetylase (HDAC)
    • Curtin ML, Garland RB, Heyman HR et al 2002 Succinimide hydroxamic acids as potent inhibitors of histone deacetylase (HDAC). Bioorg Med Chem Lett 12:2919-2923
    • (2002) Bioorg Med Chem Lett , vol.12 , pp. 2919-2923
    • Curtin, M.L.1    Garland, R.B.2    Heyman, H.R.3
  • 7
    • 0035933575 scopus 로고    scopus 로고
    • Genes modulated by histone acetylation as new effectors of butyrate activity
    • Della Ragione F, Criniti V, Della-Pietra V 2001 Genes modulated by histone acetylation as new effectors of butyrate activity. FEBS Lett 499:199-204
    • (2001) FEBS Lett , vol.499 , pp. 199-204
    • Della Ragione, F.1    Criniti, V.2    Della-Pietra, V.3
  • 9
    • 0033539092 scopus 로고    scopus 로고
    • Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors
    • Finnin MS, Donigian JR, Cohen A et al 1999 Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors. Nature 401:188-193
    • (1999) Nature , vol.401 , pp. 188-193
    • Finnin, M.S.1    Donigian, J.R.2    Cohen, A.3
  • 10
    • 0037428081 scopus 로고    scopus 로고
    • Regulating the regulators: Lysine modifications make their mark
    • Freiman RN, Tjian R 2003 Regulating the regulators: lysine modifications make their mark. Cell 112:11-17
    • (2003) Cell , vol.112 , pp. 11-17
    • Freiman, R.N.1    Tjian, R.2
  • 11
    • 18644379759 scopus 로고    scopus 로고
    • Trifluoromethyl ketones as inhibitors of histone deacetylase
    • Frey RR, Wada CK, Garland RB et al 2002 Trifluoromethyl ketones as inhibitors of histone deacetylase. Bioorg Med Chem Lett 12:3443-3447
    • (2002) Bioorg Med Chem Lett , vol.12 , pp. 3443-3447
    • Frey, R.R.1    Wada, C.K.2    Garland, R.B.3
  • 12
    • 0035793107 scopus 로고    scopus 로고
    • Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin
    • USA
    • Furumai R, Komatsu Y, Nishino N, Khochbin S, Yoshida M, Horinouchi S 2001 Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin. Proc Natl Acad Sci USA 98:87-92
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 87-92
    • Furumai, R.1    Komatsu, Y.2    Nishino, N.3    Khochbin, S.4    Yoshida, M.5    Horinouchi, S.6
  • 13
    • 0036735385 scopus 로고    scopus 로고
    • FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases
    • Furumai R, Matsuyama A, Kobashi N et al 2002 FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases. Cancer Res 62:4916-4921
    • (2002) Cancer Res , vol.62 , pp. 4916-4921
    • Furumai, R.1    Matsuyama, A.2    Kobashi, N.3
  • 14
    • 0034885248 scopus 로고    scopus 로고
    • A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies
    • Gilbert J, Baker SD, Bowling MK et al 2001 A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies. Clin Cancer Res 7:2292-2300
    • (2001) Clin Cancer Res , vol.7 , pp. 2292-2300
    • Gilbert, J.1    Baker, S.D.2    Bowling, M.K.3
  • 15
    • 18244383806 scopus 로고    scopus 로고
    • Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
    • Gottlicher M, Minucci S, Zhu P et al 2001 Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J 20:6969-6978
    • (2001) EMBO J , vol.20 , pp. 6969-6978
    • Gottlicher, M.1    Minucci, S.2    Zhu, P.3
  • 16
    • 0036008097 scopus 로고    scopus 로고
    • Deacetylase enzymes: Biological functions and the use of small-molecule inhibitors
    • Grozinger CM, Schreiber SL 2002 Deacetylase enzymes: biological functions and the use of small-molecule inhibitors. Chem Biol 9:3-16
    • (2002) Chem Biol , vol.9 , pp. 3-16
    • Grozinger, C.M.1    Schreiber, S.L.2
  • 17
    • 0037111980 scopus 로고    scopus 로고
    • Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure
    • Guan Z, Giustetto M, Lomvardas S et al 2002 Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure. Cell 111:483-493
    • (2002) Cell , vol.111 , pp. 483-493
    • Guan, Z.1    Giustetto, M.2    Lomvardas, S.3
  • 18
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD 2001 Translating the histone code. Science 293:1074-1080
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 19
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB 2002 The fundamental role of epigenetic events in cancer. Nat Rev Genet 3:415-428
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 20
    • 0009759670 scopus 로고    scopus 로고
    • Pivanex activity in refractory non-small cell lung cancer, a phase II study
    • Keer H, Reid T, Sreedharan S 2001 Pivanex activity in refractory non-small cell lung cancer, a phase II study. Proc Am Soc Clin Oncol 314a
    • (2001) Proc Am Soc Clin Oncol
    • Keer, H.1    Reid, T.2    Sreedharan, S.3
  • 21
  • 22
    • 0037905957 scopus 로고    scopus 로고
    • A phase I clinical trial of an oral formulation of the histone deacetylase inhibitor of suberoylanilide hydroxamic acid (SAHA)
    • 14th EORTC-NCI-AACR, November 2002, Frankfurt abstr 286, available
    • Kelly WK, O'Connor O, Richon VM et al 2002b A phase I clinical trial of an oral formulation of the histone deacetylase inhibitor of suberoylanilide hydroxamic acid (SAHA). 14th EORTC-NCI-AACR, November 2002, Frankfurt (abstr 286, available in Eur J Cancer 38:88)
    • (2002) Eur J Cancer , vol.38 , pp. 88
    • Kelly, W.K.1    O'Connor, O.2    Richon, V.M.3
  • 23
    • 12444321545 scopus 로고    scopus 로고
    • Phase I clinical trial of histone deacetylase inhibitor: Suberoylanilide hydroxamic acid (SAHA) administered intravenously
    • Kelly W, Richon VM, O'Connor O et al 2003 Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid (SAHA) administered intravenously. Clin Canc Res 9:3578-3588
    • (2003) Clin Canc Res , vol.9 , pp. 3578-3588
    • Kelly, W.1    Richon, V.M.2    O'Connor, O.3
  • 25
    • 0033561497 scopus 로고    scopus 로고
    • Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase
    • Kim YB, Lee KH, Sugita K, Yoshida M, Horinouchi S 1999 Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase. Oncogene 18:2461-2470
    • (1999) Oncogene , vol.18 , pp. 2461-2470
    • Kim, Y.B.1    Lee, K.H.2    Sugita, K.3    Yoshida, M.4    Horinouchi, S.5
  • 26
    • 0034654011 scopus 로고    scopus 로고
    • Acetylation: A regulatory modification to rival phosphorylation?
    • Kouzarides T 2000 Acetylation: a regulatory modification to rival phosphorylation? EMBO J 19:1176-1179
    • (2000) EMBO J , vol.19 , pp. 1176-1179
    • Kouzarides, T.1
  • 27
    • 18444414332 scopus 로고    scopus 로고
    • Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
    • Lagger G, O'Carroll D, Rembold M et al 2002 Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression. EMBO J 21:2672-2681
    • (2002) EMBO J , vol.21 , pp. 2672-2681
    • Lagger, G.1    O'Carroll, D.2    Rembold, M.3
  • 29
    • 0035480033 scopus 로고    scopus 로고
    • Control of muscle development by dueling HATs and HDACs
    • McKinsey TA, Zhang CL, Olson EN 2001 Control of muscle development by dueling HATs and HDACs. Curr Opin Genet Dev 11:497-504
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 497-504
    • McKinsey, T.A.1    Zhang, C.L.2    Olson, E.N.3
  • 30
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS 2001 Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 276:36734-36741
    • (2001) J Biol Chem , vol.276 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 31
    • 4344679396 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor for the treatment of peripheral or cutaneous T-cell lymphoma
    • Piekarz RL, Robey R, Bakke S, Sandor V, Wilson W, Bates S 2001 Histone deacetylase inhibitor for the treatment of peripheral or cutaneous T-cell lymphoma. ASCO 232b
    • (2001) ASCO
    • Piekarz, R.L.1    Robey, R.2    Bakke, S.3    Sandor, V.4    Wilson, W.5    Bates, S.6
  • 32
    • 0036261826 scopus 로고    scopus 로고
    • The diversity of acctylated proteins
    • REVIEWS0006
    • Polevoda B, Sherman F 2002 The diversity of acctylated proteins. Genome Biol 3:REVIEWS0006
    • (2002) Genome Biol , vol.3
    • Polevoda, B.1    Sherman, F.2
  • 33
    • 0035098155 scopus 로고    scopus 로고
    • Chronic oral administration of CI-994: A phase 1 study
    • Prakash S, Foster BJ, Meyer M et al 2001 Chronic oral administration of CI-994: a phase 1 study. Invest New Drugs 19:1-11
    • (2001) Invest New Drugs , vol.19 , pp. 1-11
    • Prakash, S.1    Foster, B.J.2    Meyer, M.3
  • 34
    • 0032989027 scopus 로고    scopus 로고
    • Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate
    • Qiu L, Kelso MJ, Hansen C, West ML, Fairlie DP, Parsons PG 1999 Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate. Br J Cancer 80:1252-1258
    • (1999) Br J Cancer , vol.80 , pp. 1252-1258
    • Qiu, L.1    Kelso, M.J.2    Hansen, C.3    West, M.L.4    Fairlie, D.P.5    Parsons, P.G.6
  • 35
    • 0032539890 scopus 로고    scopus 로고
    • A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases
    • USA
    • Richon VM, Emiliani S, Verdin E et al 1998 A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc Natl Acad Sci USA 95:3003-3007
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 3003-3007
    • Richon, V.M.1    Emiliani, S.2    Verdin, E.3
  • 36
    • 0034730127 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
    • USA
    • Richon VM, Sandhoff TW, Rifkind RA, Marks PA 2000 Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation. Proc Natl Acad Sci USA 97:10014-10019
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 10014-10019
    • Richon, V.M.1    Sandhoff, T.W.2    Rifkind, R.A.3    Marks, P.A.4
  • 37
    • 0033551152 scopus 로고    scopus 로고
    • A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors
    • USA
    • Saito A, Yamashita T, Mariko Y et al 1999 A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors. Proc Natl Acad Sci USA 96:4592-4597
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 4592-4597
    • Saito, A.1    Yamashita, T.2    Mariko, Y.3
  • 38
    • 0036301281 scopus 로고    scopus 로고
    • Phase I trial of the historic deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms
    • Sandor V, Bakke S, Robey RW et al 2002 Phase I trial of the historic deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms. Clin Cancer Res 8:718-728
    • (2002) Clin Cancer Res , vol.8 , pp. 718-728
    • Sandor, V.1    Bakke, S.2    Robey, R.W.3
  • 39
    • 0037726036 scopus 로고    scopus 로고
    • Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen
    • Scott GK, Marden C, Xu F, Kirk L, Benz CC 2002 Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen. Mol Cancer Ther 1:385-392
    • (2002) Mol Cancer Ther , vol.1 , pp. 385-392
    • Scott, G.K.1    Marden, C.2    Xu, F.3    Kirk, L.4    Benz, C.C.5
  • 40
    • 0037039919 scopus 로고    scopus 로고
    • Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities
    • Singh SB, Zink DL, Liesch JM et al 2002 Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities. J Org Chem 67:815-825
    • (2002) J Org Chem , vol.67 , pp. 815-825
    • Singh, S.B.1    Zink, D.L.2    Liesch, J.M.3
  • 42
    • 0034124166 scopus 로고    scopus 로고
    • A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library
    • Su GH, Sohn TA, Ryu B, Kern SE 2000 A novel histone deacetylase inhibitor identified by high-throughput transcriptional screening of a compound library. Cancer Res 60:3137-3142
    • (2000) Cancer Res , vol.60 , pp. 3137-3142
    • Su, G.H.1    Sohn, T.A.2    Ryu, B.3    Kern, S.E.4
  • 43
    • 0036613250 scopus 로고    scopus 로고
    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    • Suzuki H, Gabrielson E, Chen W et al 2002 A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet 31:141-149
    • (2002) Nat Genet , vol.31 , pp. 141-149
    • Suzuki, H.1    Gabrielson, E.2    Chen, W.3
  • 45
    • 0036850325 scopus 로고    scopus 로고
    • Cellular memory and the histone code
    • Turner BM 2002 Cellular memory and the histone code. Cell 111:285-291
    • (2002) Cell , vol.111 , pp. 285-291
    • Turner, B.M.1
  • 46
    • 0029693220 scopus 로고    scopus 로고
    • The expression of a small fraction of cellular gene is changed in response to histone hyperacetylation
    • Van Lint C, Emiliani S, Verdin E 1996 The expression of a small fraction of cellular gene is changed in response to histone hyperacetylation. Gene Expr 5:245-253
    • (1996) Gene Expr , vol.5 , pp. 245-253
    • Van Lint, C.1    Emiliani, S.2    Verdin, E.3
  • 47
    • 0033604457 scopus 로고    scopus 로고
    • Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53
    • Vrana JA, Decker RH, Johnson CR et al 1999 Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53. Oncogene 18:7016-7025
    • (1999) Oncogene , vol.18 , pp. 7016-7025
    • Vrana, J.A.1    Decker, R.H.2    Johnson, C.R.3
  • 49
    • 3643104150 scopus 로고    scopus 로고
    • Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
    • Warrell RP Jr, He LZ, Richon V, Calleja E, Pandolfi PP 1998 Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase J Natl Cancer Inst 90:1621-1615
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1621-11615
    • Warrell Jr., R.P.1    He, L.Z.2    Richon, V.3    Calleja, E.4    Pandolfi, P.P.5
  • 50
    • 0024996768 scopus 로고
    • Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
    • Yoshida M, Kijima M, Akita M, Beppu T 1990 Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J Biol Chem 265:17174-17179
    • (1990) J Biol Chem , vol.265 , pp. 17174-17179
    • Yoshida, M.1    Kijima, M.2    Akita, M.3    Beppu, T.4
  • 51
    • 0035883954 scopus 로고    scopus 로고
    • Transcription regulation by histone methylation:interplay between different covalent modifications of the core histone tails
    • Zhang Y, Reinberg D 2001 Transcription regulation by histone methylation:interplay between different covalent modifications of the core histone tails. Genes Dev 15:2343-2360
    • (2001) Genes Dev , vol.15 , pp. 2343-2360
    • Zhang, Y.1    Reinberg, D.2


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